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Literature summary for 3.4.21.35 extracted from

  • Dominek, P.; Campagnolo, P.; H-Zadeh, M.; Kraenkel, N.; Chilosi, M.; Sharman, J.A.; Caporali, A.; Mangialardi, G.; Spinetti, G.; Emanueli, C.; Pignatelli, M.; Madeddu, P.
    Role of human tissue kallikrein in gastrointestinal stromal tumour invasion (2010), Br. J. Cancer, 103, 1422-1431.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.35

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
kininogen + H2O Homo sapiens
-
 kinin + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gastrointestinal stromal tumor cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-Val-Leu-Arg-4-nitroanilide + H2O
-
 Homo sapiens D-Val-Leu-Arg + 4-nitroaniline
-
 ?
kininogen + H2O
-
 Homo sapiens kinin + ?
-
 ?

Synonyms

Synonyms Comment Organism
HK1
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function human tissue kallikrein is produced and released by gastrointestinal stromal tumor and participates in tumor invasion. Human tissue kallikrein released by gastrointestinal stromal tumor cells promotes endothelial cell migration and network formation through kinin-dependent mechanisms Homo sapiens