KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.038 | - |
L-pyroglutamyl-p-nitroanilide | 37°C, pH 7.4 | Homo sapiens | |
0.038 | - |
L-pyroglutamyl-p-nitroanilide | 37°C, pH 7.4 | Mus musculus | |
0.041 | - |
thyrotropin-releasing hormone | 37°C, pH 7.4 | Mus musculus | |
0.046 | - |
thyrotropin-releasing hormone | 37°C, pH 7.4 | Homo sapiens | |
0.054 | - |
L-pyroglutamyl-p-nitroanilide | 37°C, pH 7.4 | Rattus norvegicus | |
0.056 | - |
thyrotropin-releasing hormone | 37°C, pH 7.4 | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the enzyme might not be dominantly involved in the degradation of thyrotropin-releasing hormone in rats | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9NXJ5 | recombinant | - |
Mus musculus | Q9ESW8 | recombinant | - |
Rattus norvegicus | Q76IC5 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
renal proximal tubule | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-pyroglutamyl-p-nitroanilide + H2O | - |
Homo sapiens | L-pyroglutamate + p-nitroaniline | - |
? | |
L-pyroglutamyl-p-nitroanilide + H2O | - |
Mus musculus | L-pyroglutamate + p-nitroaniline | - |
? | |
L-pyroglutamyl-p-nitroanilide + H2O | - |
Rattus norvegicus | L-pyroglutamate + p-nitroaniline | - |
? | |
additional information | the enzyme might not be dominantly involved in the degradation of thyrotropin-releasing hormone in rats | Rattus norvegicus | ? | - |
? | |
thyrotropin-releasing hormone + H2O | - |
Homo sapiens | ? | - |
? | |
thyrotropin-releasing hormone + H2O | - |
Mus musculus | ? | - |
? | |
thyrotropin-releasing hormone + H2O | - |
Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAP-I | - |
Homo sapiens |
PAP-I | - |
Mus musculus |
PAP-I | - |
Rattus norvegicus |
pyroglutamyl aminopeptidase I | - |
Homo sapiens |
pyroglutamyl aminopeptidase I | - |
Mus musculus |
pyroglutamyl aminopeptidase I | - |
Rattus norvegicus |