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Literature summary for 3.4.19.1 extracted from

  • Santhoshkumar, P.; Xie, L.; Raju, M.; Reneker, L.; Sharma, K.K.
    Lens crystallin modifications and cataract in transgenic mice overexpressing acylpeptide hydrolase (2014), J. Biol. Chem., 289, 9039-9052.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-Ala-4-nitroanilide + H2O
-
Mus musculus acetyl-Ala + 4-nitroaniline
-
?

Synonyms

Synonyms Comment Organism
APH
-
Mus musculus

General Information

General Information Comment Organism
malfunction transgenic overexpression of APH results in crystallin cleavage, impaired lens development, and cataract Mus musculus
physiological function APH is involved in the generation of peptides that have the potential to induce protein aggregation Mus musculus