Inhibitors | Comment | Organism | Structure |
---|---|---|---|
chlorfenvinphos | IC50 at pH 7.4, 37°C: 1386 nM | Sus scrofa | |
chlorpyrifos-methyl oxon | IC50 at pH 7.4, 37°C: 18.3 nM | Sus scrofa | |
DFP | IC50 at pH 7.4, 37°C: 22.5 nM | Sus scrofa | |
diazoxon | IC50 at pH 7.4, 37°C: 1386 nM | Sus scrofa | |
dichlorvos | IC50 at pH 7.4, 37°C: 118.6 nM | Sus scrofa | |
malaoxon | IC50 at pH 7.4, 37°C: 1400000 nM | Sus scrofa | |
Mipafox | IC50 at pH 7.4, 37°C: 3013 nM | Sus scrofa | |
paraoxon | IC50 at pH 7.4, 37°C: 3805 nM | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Sus scrofa | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Sus scrofa | the enzyme may be involved in regulation of neuropeptide turnover | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme may be involved in regulation of neuropeptide turnover | Sus scrofa | ? | - |
? | |
N-acetyl-Ala-p-nitroanilide + H2O | - |
Sus scrofa | N-acetyl-Ala + p-nitroaniline | - |
? |
Synonyms | Comment | Organism |
---|---|---|
acylpeptide hydrolase | - |
Sus scrofa |
OP85 | - |
Sus scrofa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000183 | - |
IC50 at pH 7.4, 37°C: 18.3 nM | Sus scrofa | chlorpyrifos-methyl oxon | |
0.0000225 | - |
IC50 at pH 7.4, 37°C: 22.5 nM | Sus scrofa | DFP | |
0.0001186 | - |
IC50 at pH 7.4, 37°C: 118.6 nM | Sus scrofa | dichlorvos | |
0.001386 | - |
IC50 at pH 7.4, 37°C: 1386 nM | Sus scrofa | diazoxon | |
0.001386 | - |
IC50 at pH 7.4, 37°C: 1386 nM | Sus scrofa | chlorfenvinphos | |
0.003013 | - |
IC50 at pH 7.4, 37°C: 3013 nM | Sus scrofa | Mipafox | |
0.003805 | - |
IC50 at pH 7.4, 37°C: 3805 nM | Sus scrofa | paraoxon | |
1.4 | - |
IC50 at pH 7.4, 37°C: 1400000 nM | Sus scrofa | malaoxon |