Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Escherichia coli |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amoxicillin | - |
Escherichia coli | |
ampicillin | - |
Escherichia coli | |
cefaclor | - |
Escherichia coli | |
cefadroxil | - |
Escherichia coli | |
cefalexin | - |
Escherichia coli | |
cefalothin | - |
Escherichia coli | |
penicillin G | - |
Escherichia coli | |
piperacillin | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
strains K-12 and 2443 | - |
Purification (Comment) | Organism |
---|---|
ampicillin-affinity chromatography | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Nalpha,Nepsilon-diacetyl-L-Lys-D-Ala-D-Ala + H2O | - |
Escherichia coli | Nalpha,Nepsilon-diacetyl-L-Lys-D-Ala + D-alanine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DD-Carboxypeptidase | - |
Escherichia coli |
DD-CPase | - |
Escherichia coli |
PBP5 | - |
Escherichia coli |
penicillin binding protein 5 | - |
Escherichia coli |
General Information | Comment | Organism |
---|---|---|
malfunction | loss of penicillin-binding protein 5 enhances beta-lactam susceptibility, the observed susceptibilities for ampicillin, piperacillin, amoxicillin, penicillin G, cefadroxil and cefalexin are enhanced by 4fold and for cefalothin and cefaclor the susceptibilities are at least 8fold higher in the mutants | Escherichia coli |