Inhibitors | Comment | Organism | Structure |
---|---|---|---|
amastatin | - |
Mus musculus | |
amastatin | - |
Rattus norvegicus | |
puromycin | - |
Mus musculus | |
puromycin | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00095 | - |
Met-enkephalin | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
cytosol | 80% of the PSA resides in the cytosol | Mus musculus | 5829 | - |
membrane | 20% of the PSA is associated with the membrane | Mus musculus | 16020 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | Mg2+ restores the activity of the apoenzyme | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
110000 | - |
SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Mus musculus | - |
brain | - |
Rattus norvegicus | - |
cerebral cortex | - |
Mus musculus | - |
hippocampus | - |
Mus musculus | - |
hippocampus | - |
Rattus norvegicus | - |
hypothalamus | - |
Mus musculus | - |
thalamus | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Arg-enkephalin + H2O | - |
Mus musculus | L-Arg + enkephalin | - |
? | |
Met-enkephalin + H2O | - |
Rattus norvegicus | ? | releases only the N-terminal tyrosine | ? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 110000, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
GenePSA-dependent puromycin-sensitive aminopeptidase | - |
Mus musculus |
NAP | - |
Mus musculus |
NAP | - |
Rattus norvegicus |
NPEPPS | - |
Mus musculus |
PSA | - |
Mus musculus |
puromycin-sensitive aminopeptidase | - |
Mus musculus |
puromycin-sensitive neuron-aminopeptidase | - |
Mus musculus |
puromycin-sensitive neuron-aminopeptidase | - |
Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00004 | - |
amastatin | - |
Rattus norvegicus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Rattus norvegicus | isoelectric focusing | - |
5.25 |