Literature summary for 3.2.1.31 extracted from

Ce, J.; Rodrigues, M.T.; Kaefer, E.T.; da Costa Moraes, V.; Coelho, J.C.
Beta-glucuronidase activity in dried blood spots Reduced technique with biochemical parameters determined (2017), Clin. Biochem., 50, 1243-1248 .

Search for more literature for 3.2.1.31

Application

Application	Comment	Organism
diagnostics	a technique for MPS VII diagnosis is adapted for smaller amounts of sample and reagents. That will facilitate the use of smaller amounts of samples, which may be used for other techniques and to save material. Given the importance of early MPS VII diagnosis due to the severity of the disease, using reliable diagnostic techniques in dried blood spots is essential	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.25	-	4-methylumbelliferyl-beta-D-glucuronic acid	pH and temperature not specified in the publication	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P08236	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
blood	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-methylumbelliferyl-beta-D-glucuronic acid + H2O	-	Homo sapiens	4-methylumbelliferone + beta-D-glucuronic acid	-	?

Synonyms

Synonyms	Comment	Organism
GusB	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	mucopolysaccharidosis VII (MPS VII), called Sly syndrome, is caused by deficiency of the beta-glucuronidase	Homo sapiens

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Release 2023.1 (January 2023)