Literature summary for 3.1.6.18 extracted from

Dhamale, O.P.; Lawrence, R.; Wiegmann, E.M.; Shah, B.A.; Al-Mafraji, K.; Lamanna, W.C.; Luebke, T.; Dierks, T.; Boons, G.J.; Esko, J.D.
Arylsulfatase K is the lysosomal 2-sulfoglucuronate sulfatase (2017), ACS Chem. Biol., 12, 367-373 .

Search for more literature for 3.1.6.18

Cloned(Commentary)

Cloned (Comment)	Organism
expression in HEK-293 cell	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
C80A	active site mutant lacking formylglycine, is not active with substrate 2-sulfoglucuronate-N-acetylglucosamine	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q6UWY0	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-sulfoglucuronate-N-acetylglucosamine + H2O	-	Homo sapiens	D-glucuronic acid N-acetylglucosamine + sulfate	-	?
2-sulfoglucuronate-N-sulfoglucosamine + H2O	-	Homo sapiens	D-glucuronic acid N-sulfoglucosamine + sulfate	-	?
additional information	arylsulfatase K acts selectively on 2-sulfoglucuronate and lacks activity against 2-sulfoiduronate	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
ARSK	-	Homo sapiens
arylsulfatase K	-	Homo sapiens

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Release 2023.1 (January 2023)