Inhibitors | Comment | Organism | Structure |
---|---|---|---|
mixed-sequence RNAs | only a small fraction of the mixed-sequence RNA is cleaved by RNase P | Saccharomyces cerevisiae | |
poly(U) RNA | binding and structure analysis, overview | Saccharomyces cerevisiae | |
unstructured, single-stranded RNA | inhibits RNase P in a size-dependent manner, binding and structure analysis, overview | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | - |
Saccharomyces cerevisiae | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | only a small fraction of the mixed-sequence RNA is cleaved by RNase P. Binding and cleavage of unstructured RNA by nuclear RNase P, overview | Saccharomyces cerevisiae | ? | - |
? | |
pre-tRNATyr + H2O | - |
Saccharomyces cerevisiae | tRNATyr + 5' leader of tRNA | - |
? |
Synonyms | Comment | Organism |
---|---|---|
RNase P | - |
Saccharomyces cerevisiae |
General Information | Comment | Organism |
---|---|---|
physiological function | RNase P is an essential endoribonuclease processing the 59 leader of pre-tRNAs. Compared to bacterial RNase P, which contains a single small protein subunit and a large catalytic RNA subunit, eukaryotic nuclear RNase P is more complex, containing nine proteins and an RNA subunit in Saccharomyces cerevisiae. Nuclear RNase P has been shown to possess unique RNA binding capabilities, molecular recognition of nuclear RNase P, overview. Multiple interactions are required for high affinity binding | Saccharomyces cerevisiae |