Cloned (Comment) | Organism |
---|---|
mutant GG117H is expressed in CHO cells | Homo sapiens |
Crystallization (Comment) | Organism |
---|---|
mutant enzyme G117H without additives and bound to MgF3-, sulfate, echothiophate, or VX, hanging drop vapor diffusion method | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
G117H | the mutation leads to the creation of organophosphylate hydrolase activity | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P06276 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
echothiophate + H2O | substrate for mutant enzyme G117H | Homo sapiens | ? | - |
? | |
ethyl ([2-[bis(propan-2-yl)amino]ethyl]-sulfanyl)(methyl)phosphinate + H2O | substrate for mutant enzyme G117H | Homo sapiens | ? | - |
? | |
sarin + H2O | substrate for mutant enzyme G117H | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
BChE | - |
Homo sapiens |
butyrylcholinesterase | - |
Homo sapiens |