Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.2.1 extracted from

  • Wood, T.C.; Aksoy, I.A.; Aksoy, S.; Weinshilboum, R.M.
    Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization (1994), Biochem. Biophys. Res. Commun., 198, 1119-1127.
    View publication on PubMed
Search for more literature for 2.8.2.1

Cloned(Commentary)

Cloned (Comment) Organism
TL-PST, DNA and amino acid sequence determination, in vitro transcription and translation, and expression in COS-1 cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35500
-
 x * 35500, recombinant TL-PST, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + a phenol Homo sapiens sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds adenosine 3',5'-bisphosphate + an aryl sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 2 forms: thermolabile TL, thermostable TS
-

Purification (Commentary)

Purification (Comment) Organism
TL-PST Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain TL-PST Homo sapiens
-
jejunum mucosa, TL-PST Homo sapiens
-
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + a phenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
 ?
3'-phosphoadenylylsulfate + 4-nitrophenol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
 ?
3'-phosphoadenylylsulfate + a phenol sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
 ?
3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
 Homo sapiens adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
 ?
3'-phosphoadenylylsulfate + dopamine
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?

Subunits

Subunits Comment Organism
? x * 35500, recombinant TL-PST, SDS-PAGE Homo sapiens

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37.6
-
 liver TL-PST, 50% inactivation at Homo sapiens
40.4
-
 liver TS-PST, 50% inactivation at Homo sapiens