Information on EC 2.8.2.1 - aryl sulfotransferase

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The expected taxonomic range for this enzyme is: Eukaryota

EC NUMBER
COMMENTARY hide
2.8.2.1
-
RECOMMENDED NAME
GeneOntology No.
aryl sulfotransferase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
3'-phosphoadenylyl sulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate
show the reaction diagram
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
sulfate group transfer
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
dopamine degradation
-
-
melatonin degradation I
-
-
serotonin degradation
-
-
thyroid hormone metabolism II (via conjugation and/or degradation)
-
-
SYSTEMATIC NAME
IUBMB Comments
3'-phosphoadenylyl-sulfate:phenol sulfotransferase
A number of aromatic compounds can act as acceptors. Organic hydroxylamines are not substrates (cf. EC 2.8.2.9 tyrosine-ester sulfotransferase).
CAS REGISTRY NUMBER
COMMENTARY hide
9026-09-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
-
-
-
Manually annotated by BRENDA team
channel catfish
-
-
Manually annotated by BRENDA team
ST1A9
SwissProt
Manually annotated by BRENDA team
ST1A9
SwissProt
Manually annotated by BRENDA team
-
-
-
Manually annotated by BRENDA team
Mus musculus BALB/c
Balb/c mice
-
-
Manually annotated by BRENDA team
ST1a4
-
-
Manually annotated by BRENDA team
ST1c4
SwissProt
Manually annotated by BRENDA team
ST1A8
SwissProt
Manually annotated by BRENDA team
ST1C5
SwissProt
Manually annotated by BRENDA team
-
UniProt
Manually annotated by BRENDA team
-
SwissProt
Manually annotated by BRENDA team
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
-
sulfonation, catalyzed by PAPS-sulfotransferases, especially SULT2A1,is one major phase II pathways for polychlorobiphenylols conjugation and for elimination of the potentially toxic compounds, overview
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2 3'-phosphoadenylyl sulfate + 2 dopamine
2 adenosine 3',5'-bisphosphate + dopamine 3-O-sulfate + dopamine 4-O-sulfate
show the reaction diagram
SULT1A3
NMR product structure analysis, dopamine 3-O-sulfate is the main product, overview
-
?
3'-phosphoadenosine 5'-phosphosulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 1-naphthol
adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 17alpha-ethinylestradiol
?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + 17beta-estradiol
?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + 17beta-estradiol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + 2,3,3',5,5',6-hexachlorobiphenyl-4'-yl
adenosine 3',5'-bisphosphate + 2,2',3,3',5,5'-hexachlorobiphenyl-4'-yl sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + 2,3,5,5',6-pentachlorobiphenyl-4'-yl
adenosine 3',5'-bisphosphate + 2,2',3,3',5'-pentachlorobiphenyl-4'-yl sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + 2,6-dichloro-4-nitrophenol
adenosine 3',5'-bisphosphate + 2,6-dichloro-4-nitrophenyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 2-aminophenol
adenosine 3',5'-bisphosphate + 2-aminophenyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 2-methoxyestradiol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + 2-naphthol
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 2-naphthylamine
adenosine 3',5'-bisphosphate + 2-naphthylamine sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 2-naphthylamine
adenosine 3',5'-bisphosphate + naphthalen-2-ylsulfamic acid
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + 3',4',5-trichlorobiphenyl-2-yl
adenosine 3',5'-bisphosphate + 3',4',5-trichlorobiphenyl-2-yl sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + 3,4-dihydroxyphenylacetic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + 3-cyano-7-hydroxycoumarin
?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + 3-nitro-L-tyrosine
adenosine 3',5'-bisphosphate + 3-nitro-O-sulfo-L-tyrosine
show the reaction diagram
specific reaction of SULT1A3, not performed by other SULT isozymes
-
-
?
3'-phosphoadenylyl sulfate + 3-nitro-L-tyrosine
adenosine 3',5'-bisphosphate + 3-nitro-O4-sulfo-L-tyrosine
show the reaction diagram
sulfation serves as a pathway for the metabolism/regulation of nitrotyrosine, nitrotyrosine O-sulfate is released into the medium of Hep-G2 hepatoma cells
-
-
?
3'-phosphoadenylyl sulfate + 3alpha-hydroxytibolone
adenosine 3',5'-bisphosphate + 3alpha-sulfooxytibolone O-sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 3beta-hydroxytibolone
adenosine 3',5'-bisphosphate + 3beta-sulfooxytibolone O-sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 4-chlorobiphenyl-3'-ol
adenosine 3',5'-bisphosphate + 4'-chlorobiphenyl-3-yl sulfate
show the reaction diagram
low activity
-
-
?
3'-phosphoadenylyl sulfate + 4-chlorobiphenyl-4'-ol
adenosine 3',5'-bisphosphate + 4'-chlorobiphenyl-4-yl sulfate
show the reaction diagram
low activity
-
-
?
3'-phosphoadenylyl sulfate + 4-hydroxytamoxifen
adenosine 3',5'-bisphosphate + 4-(sulfooxy)tamoxifen
show the reaction diagram
3'-phosphoadenylyl sulfate + 4-methylumbelliferone
adenosine 3',5'-bisphosphate + 4-methylumbelliferyl sulfate
show the reaction diagram
-
-
-
-
r
3'-phosphoadenylyl sulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 5-amino-2-(4-amino-3-fluorophenyl)-6,8-difluoro-7-methyl-4H-1-benzopyran-4-one
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + 5-chloro-7-iodo-8-quinolinol
adenosine 3',5'-bisphosphate + 5-chloro-7-iodo-8-quinolinyl sulfate
show the reaction diagram
-
isoform SULT1A3 is responsible for the 5-chloro-7-iodo-8-quinolinol sulfation in human jejunum
-
-
?
3'-phosphoadenylyl sulfate + 6-hydroxydopamine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + 7-hydroxycoumarin
adenosine 3',5'-bisphosphate + 7-hydroxycoumarin sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + 7-hydroxyserotonin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + a phenol
adenosine 3',5'-bisphosphate + an aryl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + acetaminophen
adenosine 3',5'-bisphosphate + 4-(acetylamino)phenylsulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + apigenin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + aristolochic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + beta-estradiol
adenosine 3',5'-bisphosphate + beta-estradiol 3-sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + beta-naphthol
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + bisphenol A
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
isoform ST3 also shows sulfating activity toward bisphenol A
-
-
?
3'-phosphoadenylyl sulfate + butylated hydroxyanisole
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + butylparaben
adenosine 3',5'-bisphosphate + butylparaben sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + caffeic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + catechin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + catechol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + chrysin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
substrate of allozyme SULT1A1*1
-
-
?
3'-phosphoadenylyl sulfate + daidzein
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + desipramine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + DL-3-hydroxyphenylalanine
adenosine 3',5'-bisphosphate + DL-3-(sulfooxy)phenylalanine
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + dopamine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + dopamine
adenosine 3',5'-bisphosphate + dopamine sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + dopamine
adenosine 3',5'-bisphosphate + dopaminyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + epicatechin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + epigallocatechin gallate
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + estradiol
adenosine 3',5'-bisphosphate + estradiol sulfate
show the reaction diagram
-
the enzyme also performs the reaction of EC 2.8.2.4, estrone sulfotransferase, with low activity
-
-
?
3'-phosphoadenylyl sulfate + fenoterol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
as fenoterol hydrobromide
-
-
?
3'-phosphoadenylyl sulfate + genistein
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + isoproterenol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
as isoproterenol hydrochloride
-
-
?
3'-phosphoadenylyl sulfate + isoproterenol
adenosine 3',5'-bisphosphate + isoproterenol sulfate
show the reaction diagram
as isoproterenol hydrochloride
-
-
?
3'-phosphoadenylyl sulfate + kaempferol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + L-DOPA
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + L-triiodothyronine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + L-tyrosine
adenosine 3',5'-bisphosphate + O-sulfo-L-tyrosine
show the reaction diagram
low activity
-
-
?
3'-phosphoadenylyl sulfate + minoxidil
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + myricetin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + N-hydroxy-4-aminobiphenyl
adenosine 3',5'-bisphosphate + N-(sulfooxy)biphenyl 4-amine
show the reaction diagram
3'-phosphoadenylyl sulfate + N-hydroxy-4-aminobiphenyl
adenosine 3',5'-bisphosphate + N-(sulfooxy)biphenyl-4-amine
show the reaction diagram
SULT1C*2
-
-
?
3'-phosphoadenylyl sulfate + n-propyl gallate
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + nonyl phenol
adenosine 3',5'-bisphosphate + nonyl phenyl sulfate
show the reaction diagram
low activity
-
-
?
3'-phosphoadenylyl sulfate + octyl phenol
adenosine 3',5'-bisphosphate + octyl phenyl sulfate
show the reaction diagram
low activity
-
-
?
3'-phosphoadenylyl sulfate + p-nitrophenol
adenosine 3',5'-bisphosphate + p-nitrophenyl sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + pentachlorophenol
adenosine 3',5'-bisphosphate + pentachlorophenyl sulfate
show the reaction diagram
3'-phosphoadenylyl sulfate + phenol
adenosine 3',5'-bisphosphate + phenyl sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + quercetin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylyl sulfate + resveratrol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + resveratrol
adenosine 3',5'-bisphosphate + trans-resveratrol-3-O sulfate
show the reaction diagram
-
3,4',5-trihydroxy-trans-stilbene
-
-
?
3'-phosphoadenylyl sulfate + ritodrine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
as ritodrine hydrochloride
-
-
?
3'-phosphoadenylyl sulfate + salbutamol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
as salbutamol hemisulfate
-
-
?
3'-phosphoadenylyl sulfate + serotonin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylyl sulfate + silybin B
adenosine 3',5'-bisphosphate + silybin B 20-O-sulfate
show the reaction diagram
-
-
-
?
3'-phosphoadenylyl sulfate + terbutaline
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
as terbutaline hemisulfate
-
-
?
3'-phosphoadenylyl sulfate + trans-4-hydroxytamoxifen
adenosine 3',5'-bisphosphate + trans-4-(sulfooxy)tamoxifen
show the reaction diagram
substrate of the allozymes SULT1A1*2 and SULT1A1*1
-
-
?
3'-phosphoadenylyl sulfate + vanillin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
vanillin is the best substrate for isoforms ST1 and ST3
-
-
?
3'-phosphoadenylyl sulfate + xanthurenic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + (+/-)isoproterenol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST and M-PST
-
-
?
3'-phosphoadenylylsulfate + (+/-)metoprolol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST, not M-PST
-
-
?
3'-phosphoadenylylsulfate + (+/-)salbutamol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST and M-PST
-
-
?
3'-phosphoadenylylsulfate + (+/-)sotalol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST, not M-PST
-
-
?
3'-phosphoadenylylsulfate + (-)-(1R,2R)-pseudoephedrine
adenosine 3',5'-bisphosphate + 2-(methylamino)-1-phenylpropyl sulfate
show the reaction diagram
-
absolute stereospecificity
-
-
?
3'-phosphoadenylylsulfate + (-)-(1R,2S)-ephedrine
adenosine 3',5'-bisphosphate + 2-(methylamino)-1-phenylpropyl sulfate
show the reaction diagram
-
absolute stereospecificity
-
-
?
3'-phosphoadenylylsulfate + (-)-(S)-2-methyl-1-phenyl-1-propanol
adenosine 3',5'-bisphosphate + 2-methyl-1-phenylpropyl 1-sulfate
show the reaction diagram
-
absolute stereospecificity
-
-
?
3'-phosphoadenylylsulfate + 1,2,3,4-tetrahydro-1-naphthol
adenosine 3',5'-bisphosphate + 1,2,3,4-tetrahydronaphthyl 1-sulfate
show the reaction diagram
-
only the (-)-(R)-enantiomer is active as substrate
-
-
?
3'-phosphoadenylylsulfate + 1-naphthol
adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 1-phenylethanol
adenosine 3',5'-bisphosphate + 1-phenylethyl sulfate
show the reaction diagram
-
(+)-(R)- and (-)-(S)-
-
-
?
3'-phosphoadenylylsulfate + 2-amino-4'-hydroxy-1-methyl-6-phenylimidazo[4,5-b]pyridine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 2-chlorophenol
adenosine 3',5'-bisphosphate + 2-chlorophenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 2-ethylphenol
adenosine 3',5'-bisphosphate + 2-ethylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 2-hydroxyestradiol
adenosine 3',5'-bisphosphate + estradiol 2-sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 2-hydroxyestrone
adenosine 3',5'-bisphosphate + estrone 2-sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 2-methylphenol
adenosine 3',5'-bisphosphate + 2-methylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 2-naphthol
adenosine 3',5'-bisphosphate + 2-naphthyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 2-naphthol
adenosine 3',5'-bisphosphate + 2-naphthylsulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 2-naphthylamine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
SULT-N
-
-
?
3'-phosphoadenylylsulfate + 2-nitrophenol
adenosine 3',5'-bisphosphate + 2-nitrophenyl sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 3,3',5'-triiodo-L-thyronine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 3,3',5-triiodo-D-thyronine
adenosine 3',5'-bisphosphate + 3,3',5-triiodo-D-thyronine 4'-sulfate
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + 3,3',5-triiodo-D-thyronine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 3,3',5-triiodo-L-thyronine
adenosine 3',5'-bisphosphate + 3,3',5-triiodo-L-thyronine 4'-sulfate
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + 3,3',5-triiodo-L-thyronine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 3,3'-diiodo-L-thyronine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 3,4-dihydroxyphenylacetate
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 3,4-dihydroxyphenylacetic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 3,4-dihydroxyphenylglycol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 3,5-diiodo-L-thyronine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 3-chlorophenol
adenosine 3',5'-bisphosphate + 3-chlorophenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 3-ethylphenol
adenosine 3',5'-bisphosphate + 3-ethylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 3-hydroxybenzo[a]pyrene
adenosine 3',5'-bisphosphate + benzo[a]pyrene 3-sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 3-hydroxyindole
adenosine 3',5'-bisphosphate + 3-indoxyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 3-methoxy-4-hydroxyphenylethyleneglycol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 3-methoxy-4-hydroxyphenylglycol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 3-methylphenol
adenosine 3',5'-bisphosphate + 3-methylphenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 3-nitrophenol
adenosine 3',5'-bisphosphate + 3-nitrophenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 4-acetamidophenol
adenosine 3',5'-bisphosphate + 4-acetamidophenyl sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-chlorocatechol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 4-chlorophenol
adenosine 3',5'-bisphosphate + 4-chlorophenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 4-ethylphenol
adenosine 3',5'-bisphosphate + 4-ethylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 4-hydroxy-3-methoxyphenylglycol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 4-isopropylcatechol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 4-methoxyphenol
adenosine 3',5'-bisphosphate + 4-methoxyphenyl sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-methoxytyramine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 4-methylcatechol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 4-methylphenol
adenosine 3',5'-bisphosphate + 4-methylphenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 4-methylumbelliferone
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 4-n-amylphenol
adenosine 3',5'-bisphosphate + 4-n-amylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 4-n-butylphenol
adenosine 3',5'-bisphosphate + 4-n-butylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 4-n-propylphenol
adenosine 3',5'-bisphosphate + 4-n-propylphenyl sulfate
show the reaction diagram
-
SULT1A1/2
-
-
?
3'-phosphoadenylylsulfate + 4-nitrophenol
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 4-nonylphenol
adenosine 3',5'-bisphosphate + 4-nonylphenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 4-octylphenol
adenosine 3',5'-bisphosphate + 4-octylphenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 5,7-dihydroxyflavanone
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 5-(hydroxyphenyl)-5-(p-tolyl)-hydantoin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 5-hydroxyindole
adenosine 3',5'-bisphosphate + 5-indoxyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 5-hydroxytryptamine
adenosine 3',5'-bisphosphate + 3-(2-aminoethyl)-5-indoxyl sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 5-hydroxytryptophol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + 6-hydroxymelatonin
adenosine 3',5'-bisphosphate + melatonin 6-sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + 7-(hydroxymethyl)-12-methylbenz[a]anthracene
adenosine 3',5'-bisphosphate + sulfuric acid mono-(12-methyl-benzo[a]anthracen-7ylmethyl)ester
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 7-hydroxybenzo[a]pyrene
adenosine 3',5'-bisphosphate + benzo[a]pyrene 7-sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + 9-hydroxybenzo[a]pyrene
adenosine 3',5'-bisphosphate + benzo[a]pyrene 9-sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + a phenol
adenosine 3',5'-bisphosphate + an aryl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + acebutolol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST, not M-PST
-
-
?
3'-phosphoadenylylsulfate + acetaminophen
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + adrenaline
adenosine 3',5'-bisphosphate + adrenaline sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + beta-estradiol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + bisphenol A
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + bupivacaine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST, not M-PST
-
-
?
3'-phosphoadenylylsulfate + butylated hydroxyanisole
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + caffeic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + catechin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + catechol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + catecholamine metabolites
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
deaminated and (or) O-methylated
-
-
?
3'-phosphoadenylylsulfate + chlorogenic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + cinnamyl alcohol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + D-3,4-dihydroxyphenylalanine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + D-tyrosine
adenosine 3',5'-bisphosphate + D-tyrosyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + daidzein
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + daidzein
adenosine 3',5'-bisphosphate + daidzein 4'-sulfate
show the reaction diagram
-
enzyme form SULT1A3
-
-
?
3'-phosphoadenylylsulfate + daidzein
adenosine 3',5'-bisphosphate + daidzein 7-sulfate + daidzein 4'-sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + daidzein 4'-sulfate
adenosine 3',5'-bisphosphate + daidzein 4',7-disulfate
show the reaction diagram
3'-phosphoadenylylsulfate + daidzein 7-sulfate
adenosine 3',5'-bisphosphate + daidzein 4',7-disulfate
show the reaction diagram
3'-phosphoadenylylsulfate + dehydroepiandrosterone
adenosine 3',5'-bisphosphate + dehydroepiandrosterone sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + dexamethasone
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST, not M-PST
-
-
?
3'-phosphoadenylylsulfate + DL-propanolol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST, not M-PST
-
-
?
3'-phosphoadenylylsulfate + DL-tyrosine
adenosine 3',5'-bisphosphate + DL-tyrosyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + dobutamine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST and M-PST
-
-
?
3'-phosphoadenylylsulfate + dopamine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + epinephrine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
enzyme form SULT1A3
-
-
?
3'-phosphoadenylylsulfate + epinephrine
adenosine 3',5'-bisphosphate + epinephrine sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + gallic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + genistein
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + genistein
adenosine 3',5'-bisphosphate + genistein 4'-sulfate
show the reaction diagram
-
enzyme form SULT1A3
-
-
?
3'-phosphoadenylylsulfate + genistein
adenosine 3',5'-bisphosphate + genistein 7-sulfate + genistein 4'-sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + genistein 4'-sulfate
adenosine 3',5'-bisphosphate + genistein 4',7-disulfate
show the reaction diagram
3'-phosphoadenylylsulfate + genistein 7-sulfate
adenosine 3',5'-bisphosphate + genistein 4',7-disulfate
show the reaction diagram
3'-phosphoadenylylsulfate + guaiacol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
ST1c4
-
-
?
3'-phosphoadenylylsulfate + harmol
adenosine 3',5'-bisphosphate + harmol sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + homovanillic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + hydroquinone
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + hydroxybiphenyl
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + kaempferol
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + L-3,4-dihydroxyphenylalanine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + L-4-hydroxyphenylglycine
adenosine 3',5'-bisphosphate + (2S)-amino[4-(sulfooxy)phenyl]ethanoic acid
show the reaction diagram
-
no activity with the D-isomer
-
-
?
3'-phosphoadenylylsulfate + L-thyroxine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + L-thyroxine
adenosine 3',5'-bisphosphate + L-thyroxine 4'-sulfate
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + L-tyrosine
adenosine 3',5'-bisphosphate + L-tyrosyl O4-sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + lidocaine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
P-PST and M-PST
-
-
?
3'-phosphoadenylylsulfate + minoxidil
adenosine 3',5'-bisphosphate + minoxidil sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + myricetin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + n-propyl gallate
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + naringenin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + norepinephrine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
enzyme form SULT1A3
-
-
?
3'-phosphoadenylylsulfate + norepinephrine
adenosine 3',5'-bisphosphate + norepinephrine sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + normetanephrine
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + phenol
adenosine 3',5'-bisphosphate + phenyl sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + phentolamine
adenosine 3',5'-bisphosphate + phentolamine sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + quercetin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
recombinant enzyme form SULT1 ST5
-
-
?
3'-phosphoadenylylsulfate + ritodrine
adenosine 3',5'-bisphosphate + ritodrine sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + sakuranetin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + salicylamide
adenosine 3',5'-bisphosphate + 2-sulfooxybenzamide
show the reaction diagram
3'-phosphoadenylylsulfate + serotonin
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + troglitazone
adenosine 3',5'-bisphosphate + troglitazone sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + tyramine
adenosine 3',5'-bisphosphate + tyramine O-sulfate
show the reaction diagram
3'-phosphoadenylylsulfate + umbelliferone
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
3'-phosphoadenylylsulfate + vanillin
adenosine 3',5'-bisphosphate + 3-methoxybenzaldehyde 4-sulfate
show the reaction diagram
-
-
-
-
?
3'-phosphoadenylylsulfate + vanillylmandelic acid
adenosine 3',5'-bisphosphate + ?
show the reaction diagram
-
-
-
-
?
adenosine 2',3'-cyclic phosphate 5'-phosphate + 4-nitrophenyl sulfate
adenosine 2',3'-cyclic phosphate 5'-phosphate 5'-sulfate + 4-nitrophenol
show the reaction diagram
-
sulfation at 5'-position
-
?
adenosine 2',5'-bisphosphate + 4-nitrophenyl sulfate
adenosine 2'-phosphate 5'-phosphate 5'-sulfate + 4-nitrophenol
show the reaction diagram
-
sulfation at 5'-position
-
?
adenosine 3',5'-bisphosphate + 4-methylumbelliferyl sulfate
3'-phosphoadenylyl sulfate + 4-methylumbelliferone
show the reaction diagram
-
-
-
-
r
adenosine 3',5'-bisphosphate + dopamine sulfate
3'-phosphoadenylyl sulfate + dopamine
show the reaction diagram
-
-
-
-
r
AMP + 4-nitrophenyl sulfate
adenosine 5'-phosphate 5'-sulfate + 4-nitrophenol
show the reaction diagram
-
sulfation at 5'-position
-
?
additional information
?
-