Cloned (Comment) | Organism |
---|---|
- |
Tetrahymena thermophila |
Protein Variants | Comment | Organism |
---|---|---|
C232A | mutation in CP2 motif, modest defect in RNA binding | Tetrahymena thermophila |
F230A | mutation in CP2 motif, no effect on RNA binding | Tetrahymena thermophila |
H234A | mutation in CP2 motif, modest defect in RNA binding | Tetrahymena thermophila |
I229A | mutation in CP2 motif, modest defect in RNA binding | Tetrahymena thermophila |
R226A | mutation in CP2 motif, strong defect in RNA binding | Tetrahymena thermophila |
R237A | mutation in CP2 motif, strong defect in RNA binding | Tetrahymena thermophila |
Y231A | mutation in CP2 motif, no effect on RNA binding | Tetrahymena thermophila |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
40000 | - |
gel filtration | Tetrahymena thermophila |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tetrahymena thermophila | O77448 | - |
- |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 40000, SDS-PAGE | Tetrahymena thermophila |
General Information | Comment | Organism |
---|---|---|
physiological function | the CP2 motif is in close proximity to a conserved region known as the template boundary element and acts as a RNA binding determinant. The CP2 motif binds the template boundary element to strictly define which telomerase RNA nucleotides can be reverse transcribed | Tetrahymena thermophila |