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Literature summary for 2.7.3.1 extracted from

  • Pradel, L.A.; Kassab, R.; van Thoai, N.
    On ATP:guanidinoacetate N-phosphotransferase (1964), Biochim. Biophys. Acta, 81, 86-95.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Chloroacetophenone
-
Nephtys caeca
iodoacetic acid
-
Nephtys caeca
N-ethylmaleimide
-
Nephtys caeca
NH2OH
-
Nephtys caeca
p-chloromercuribenzoate
-
Nephtys caeca
phenylhydrazine inhibits phosphorylation of ADP Nephtys caeca

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.33
-
Guanidinoacetate
-
Nephtys caeca
3.3
-
ATP
-
Nephtys caeca
6.8
-
phosphoguanidinoacetate
-
Nephtys caeca
10
-
ADP
-
Nephtys caeca

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ slightly Nephtys caeca
Mg2+
-
Nephtys caeca
Mn2+
-
Nephtys caeca

Organism

Organism UniProt Comment Textmining
Nephtys caeca
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
Nephtys caeca
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADP + phosphocreatine poor substrate Nephtys caeca ATP + ?
-
?
ADP + phosphoguanidinoacetate
-
Nephtys caeca ATP + guanidinoacetate
-
?
ATP + guanidinoacetate not: arginine, creatine, lombricine Nephtys caeca ADP + phosphoguanidinoacetate
-
r

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
phosphorylation of guanidinoacetate Nephtys caeca
40
-
optimum above, phosphorylation of ADP Nephtys caeca

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
16 32 less than 50% of maximal activity above and below, phosphorylation of guanidinoacetate Nephtys caeca

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
phosphorylation of ADP Nephtys caeca
8.9
-
phosphorylation of guanidinoacetate Nephtys caeca