Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2,5-hexanedione | CDK5 contents and activities in sciatic nerve of rats treated with 200 or 400 mg/kg 2,5-hexanedione are significantly increased in both the cytosolic and membrane fractions, increase of CDK5 content in both the cytosolic and membrane fractions of spinal cord in 200 and 400 mg/kg 2,5-hexanedione-treated rats are observed | Rattus norvegicus | |
p35 | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,5-hexanedione | activities of CDK5 in cerebral cortex of 200 or 400 mg/kg 2,5-hexanedione-treated rats are significantly decreased in both the cytosolic and membrane fractions, CDK5 activities are significantly decreased in the cytosolic fraction of spinal cord cord in 200 and 400 mg/kg 2,5-hexanedione-treated rats | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
membrane | - |
Rattus norvegicus | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
cerebral cortex | - |
Rattus norvegicus | - |
sciatic nerve | - |
Rattus norvegicus | - |
spinal cord | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + histone H1 | - |
Rattus norvegicus | ADP + phosphorylated histone H1 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cdk5 | - |
Rattus norvegicus |
cyclin-dependent kinase 5 | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cyclin | - |
Rattus norvegicus |