Inhibitors | Comment | Organism | Structure |
---|---|---|---|
[(1E)-7-bromo-2-carboxyhept-1-en-1-yl]phosphonate | inhibitor based on vinyl phosphonate, designed to fit into the binding sites of both phosphoenolpyruvate and D-erythrose 4-phosphate substrates simultaneously. Competitive with respect to phosphoenolpyruvate | Escherichia coli | |
[2-carboxy-7-(phosphonatooxy)hept-1-en-1-yl]phosphonate | inhibitor based on vinyl phosphonate ratio Z:E enantiomer 1:1. Inhibitor is designed to fit into the binding sites of both phosphoenolpyruvate and D-erythrose 4-phosphate substrates simultaneously. Competitive with respect to phosphoenolpyruvate | Escherichia coli | |
[2-carboxy-7-(phosphonatooxy)hept-2-en-1-yl]phosphonate | inhibitor based on allyl phosphonate, ratio Z:E enantiomer 7:3. Inhibitor is designed to fit into the binding sites of both phosphoenolpyruvate and D-erythrose 4-phosphate substrates simultaneously. Competitive with respect to phosphoenolpyruvate | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0036 | - |
pH not specified in the publication, temperature not specified in the publication | Escherichia coli | [(1E)-7-bromo-2-carboxyhept-1-en-1-yl]phosphonate | |
0.0053 | - |
pH not specified in the publication, temperature not specified in the publication | Escherichia coli | [2-carboxy-7-(phosphonatooxy)hept-1-en-1-yl]phosphonate | |
0.154 | - |
pH not specified in the publication, temperature not specified in the publication | Escherichia coli | [2-carboxy-7-(phosphonatooxy)hept-2-en-1-yl]phosphonate |