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Literature summary for 2.5.1.54 extracted from

  • Helmstaedt, K.; Strittmatter, A.; Lipscomb, W.N.; Braus, G.H.
    Evolution of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae (2005), Proc. Natl. Acad. Sci. USA, 102, 9784-9789.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
P165G inhibited by tryptophan Saccharomyces cerevisiae
Q302R inhibited by tryptophan Saccharomyces cerevisiae
S195A inhibited by tryptophan Saccharomyces cerevisiae

Inhibitors

Inhibitors Comment Organism Structure
L-tyrosine almost complete inhibition at 0.5 mM Saccharomyces cerevisiae
additional information not inhibited by tryptophan Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Saccharomyces cerevisiae 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?

Synonyms

Synonyms Comment Organism
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase
-
Saccharomyces cerevisiae
Aro4p
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Saccharomyces cerevisiae
DAHP synthase
-
Saccharomyces cerevisiae