Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | - |
Escherichia coli | |
Mn2+ | - |
Escherichia coli | |
Zn2+ | - |
Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
isoform AroG | - |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate | product release is rate-limiting, rate constant for product formation is higher with Mn2+ than with Zn2+ or Cu2+. Role of metal ion is to position the amino acids with the appropriate geometry required to coordinate and activate the water molecule | Escherichia coli |