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Literature summary for 2.5.1.54 extracted from

  • Kim, K.J.
    Regulation of 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP) synthase of Bacillus sp. B-6 producing phenazine-1-carboxylic acid (2001), J. Biochem. Mol. Biol., 34, 299-304.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
chorismate 50% at 0.12 mM; feedback inhibition, noncompetitive against D-erythrose 4-phosphate and phosphoenolpyruvate Bacillus sp. (in: Bacteria)
additional information no inhibition by aromatic amino acids, folic acid, phenazine 1-carboxylic acid, anthranilic acid, shikimic acid, p-aminobenzoic acid and 3-hydroxyanthranilic acid Bacillus sp. (in: Bacteria)
prephenate 50% at 0.02 mM; feedback inhibition, noncompetitive against D-erythrose 4-phosphate and phosphoenolpyruvate Bacillus sp. (in: Bacteria)

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O Bacillus sp. (in: Bacteria) first enzyme of aromatic amino acids, folic acid and phenazine 1-carboxylic acid biosynthesis pathways 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O Bacillus sp. (in: Bacteria) B-6 first enzyme of aromatic amino acids, folic acid and phenazine 1-carboxylic acid biosynthesis pathways 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Bacillus sp. (in: Bacteria)
-
-
-
Bacillus sp. (in: Bacteria) B-6
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Bacillus sp. (in: Bacteria) 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O first enzyme of aromatic amino acids, folic acid and phenazine 1-carboxylic acid biosynthesis pathways Bacillus sp. (in: Bacteria) 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
Bacillus sp. (in: Bacteria) B-6 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?
phosphoenolpyruvate + D-erythrose 4-phosphate + H2O first enzyme of aromatic amino acids, folic acid and phenazine 1-carboxylic acid biosynthesis pathways Bacillus sp. (in: Bacteria) B-6 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
assay at Bacillus sp. (in: Bacteria)

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Bacillus sp. (in: Bacteria)