Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21-CodonPlus (DE3)-RIL cells | Dermanyssus gallinae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-nitrobenzyl chloride | 50.8% inhibition of isoform GST-1 at 1 mM, 18.1% inhibition of isoform GST-2 at 1 mM, 33.3% inhibition of isoform GST-3 at 1 mM | Dermanyssus gallinae | |
abamectin | 17% inhibition of isoform GST-1 at 0.1 mM | Dermanyssus gallinae | |
additional information | isoforms GST-2 and GST-3 are not inhibited by permethrin and abamectin. Isoforms GST-1, GST-2, and GST3 are not inhibited by spinosad | Dermanyssus gallinae | |
permethrin | 35% inhibition of isoform GST-1 at 0.1 mM | Dermanyssus gallinae | |
phoxim | 56% inhibition of isoform GST-1 at 0.1 mM, 14.8% inhibition of isoform GST-2 at 0.1 mM, 20.6% inhibition of isoform GST-3 at 0.1 mM | Dermanyssus gallinae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dermanyssus gallinae | - |
poultry red mite | - |
Purification (Comment) | Organism |
---|---|
affinity column chromatography | Dermanyssus gallinae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-chloro-2,4-dinitrobenzene + glutathione | isoform GST-1 is 18.3times more active than GST-2 and 26.8times more active than GST-3 | Dermanyssus gallinae | S-(2,4-dinitrophenyl)glutathione + HCl | - |
? |
Synonyms | Comment | Organism |
---|---|---|
glutathione S-transferase | - |
Dermanyssus gallinae |
GST-1 | isoform | Dermanyssus gallinae |
GST-2 | isoform | Dermanyssus gallinae |
GST-3 | isoform | Dermanyssus gallinae |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme isoforms play important roles in the detoxification of pesticides | Dermanyssus gallinae |