Cloned (Comment) | Organism |
---|---|
OCH1 gene encodes Och1p, an alpha-1,6-mannosyltransferase | Saccharomyces cerevisiae |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Saccharomyces cerevisiae | Och1p is essential for the outer chain elongation of N-linked oligosaccharides | ? | - |
? | |
additional information | Saccharomyces cerevisiae Och1p | Och1p is essential for the outer chain elongation of N-linked oligosaccharides | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
Och1p | - |
Saccharomyces cerevisiae Och1p | - |
Och1p | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GDP-mannose + Man8GlcNAc2-PA | best acceptor for Och1p, initiation-specific alpha-1,6-mannosyltransferase that requires the intact structure of Man8GlcNAc for efficient mannose outer chain initiation | Saccharomyces cerevisiae | GDP + Man9GlcNAc2-PA | additional Man is attached with an alpha-1,6-linkage at the site where mannose outer chain elongation initiates | ? | |
GDP-mannose + Man8GlcNAc2-PA | best acceptor for Och1p, initiation-specific alpha-1,6-mannosyltransferase that requires the intact structure of Man8GlcNAc for efficient mannose outer chain initiation | Saccharomyces cerevisiae Och1p | GDP + Man9GlcNAc2-PA | additional Man is attached with an alpha-1,6-linkage at the site where mannose outer chain elongation initiates | ? | |
GDP-mannose + pyridylaminated oligosaccharide acceptor | substrate specificity | Saccharomyces cerevisiae | ? | - |
? | |
GDP-mannose + pyridylaminated oligosaccharide acceptor | various high mannose-type oligosaccharides as acceptors, Man8GlcNAc2-PA is the best acceptor, the loss of 1 or 2 alpha-1,2-mannoses from Man8GlcNAc2 reduces the activity | Saccharomyces cerevisiae | ? | - |
? | |
GDP-mannose + pyridylaminated oligosaccharide acceptor | substrate specificity | Saccharomyces cerevisiae Och1p | ? | - |
? | |
GDP-mannose + pyridylaminated oligosaccharide acceptor | various high mannose-type oligosaccharides as acceptors, Man8GlcNAc2-PA is the best acceptor, the loss of 1 or 2 alpha-1,2-mannoses from Man8GlcNAc2 reduces the activity | Saccharomyces cerevisiae Och1p | ? | - |
? | |
additional information | no acceptors for Och1p: Man5GlcNAc2 completely lacking alpha-1,2-Man, Man8GlcNAcOH | Saccharomyces cerevisiae | ? | - |
? | |
additional information | Och1p is essential for the outer chain elongation of N-linked oligosaccharides | Saccharomyces cerevisiae | ? | - |
? | |
additional information | no acceptors for Och1p: Man5GlcNAc2 completely lacking alpha-1,2-Man, Man8GlcNAcOH | Saccharomyces cerevisiae Och1p | ? | - |
? | |
additional information | Och1p is essential for the outer chain elongation of N-linked oligosaccharides | Saccharomyces cerevisiae Och1p | ? | - |
? |