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BRENDA support

Literature summary for 2.3.1.87 extracted from

  • Alkozi, H.; de Lara, M.; Sanchez-Naves, J.; Pintor, J.
    TRPV4 stimulation induced melatonin secretion by increasing arylalkymine N-acetyltransferase (AANAT) protein level (2017), Int. J. Mol. Sci., 18, 746 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Homo sapiens Q16613
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Source Tissue

Source Tissue Comment Organism Textmining
ciliary body
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 Homo sapiens
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epithelium ciliar body epithelial cells Homo sapiens
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Expression

Organism Comment Expression
Homo sapiens after 18 h incubation with TRPV4 channel agonist GSK1016790A, AANAT level increases 2.4fold up

General Information

General Information Comment Organism
physiological function AANAT levels and melatonin synthesis increase after TRPV4 channel stimulation in ciliary body epithelium Homo sapiens