Application | Comment | Organism |
---|---|---|
medicine | GPAT3 may be useful as a target for the treatment of obesity | Mus musculus |
medicine | GPAT3 may be useful as a target for the treatment of obesity | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
GPAT3 is localized to the endoplasmic reticulum when overexpressed in COS-7 cells | Mus musculus |
GPAT3 is localized to the endoplasmic reticulum when overexpressed in COS-7 cells | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Mus musculus | 5783 | - |
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + sn-glycerol 3-phosphate | Mus musculus | key enzyme in de novo triacylglycerol synthesis | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
acyl-CoA + sn-glycerol 3-phosphate | Homo sapiens | key enzyme in de novo triacylglycerol synthesis | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adipocyte | GPAT3 mRNA is dramatically upregulated during adipocyte differentiation | Mus musculus | - |
adipocyte | GPAT3 mRNA is dramatically upregulated during adipocyte differentiation | Homo sapiens | - |
adipose tissue | - |
Homo sapiens | - |
brown adipose tissue | - |
Mus musculus | - |
colon | - |
Mus musculus | - |
heart | - |
Mus musculus | - |
heart | - |
Homo sapiens | - |
kidney | - |
Mus musculus | - |
kidney | - |
Homo sapiens | - |
lung | - |
Homo sapiens | - |
skeletal muscle | - |
Homo sapiens | - |
small intestine | - |
Mus musculus | - |
testis | - |
Homo sapiens | - |
thyroid gland | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + sn-glycerol 3-phosphate | key enzyme in de novo triacylglycerol synthesis | Mus musculus | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
acyl-CoA + sn-glycerol 3-phosphate | key enzyme in de novo triacylglycerol synthesis | Homo sapiens | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
lauroyl-CoA + sn-glycerol 3-phosphate | - |
Mus musculus | CoA + 1-lauroyl-sn-glycerol 3-phosphate | - |
? | |
lauroyl-CoA + sn-glycerol 3-phosphate | - |
Homo sapiens | CoA + 1-lauroyl-sn-glycerol 3-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ER-associated GPAT | - |
Mus musculus |
ER-associated GPAT | - |
Homo sapiens |
GPAT3 | - |
Mus musculus |
GPAT3 | - |
Homo sapiens |