Activating Compound | Comment | Organism | Structure |
---|---|---|---|
phosphatidylcholine | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
5,5'-dithiobis(2-nitro-benzoate) | - |
Rattus norvegicus | |
acyl-CoA | strong substrate inhibition | Rattus norvegicus | |
N-ethylmaleimide | - |
Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.2 | - |
sn-glycerol 3-phosphate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Rattus norvegicus | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Rattus norvegicus | |
Co2+ | at high concentrations | Rattus norvegicus | |
Mg2+ | activation, slightly less than Ca2+ | Rattus norvegicus | |
Mn2+ | less effective than Ca2+ | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male | - |
Rattus norvegicus | - |
Wistar strain | - |
Rattus norvegicus Wistar | - |
Wistar strain | - |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0022 | - |
- |
Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acyl-CoA + sn-glycerol 3-phosphate | exclusively acylates glycerol 3-phosphate at the C-1-position | Rattus norvegicus | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
acyl-CoA + sn-glycerol 3-phosphate | exclusively acylates glycerol 3-phosphate at the C-1-position | Rattus norvegicus Wistar | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
arachidonoyl-CoA + sn-glycerol 3-phosphate | poor substrate | Rattus norvegicus | CoA + 1-arachidonoyl-sn-glycerol 3-phosphate | - |
? | |
linoleoyl-CoA + sn-glycerol 3-phosphate | poor substrate | Rattus norvegicus | CoA + 1-linoleoyl-sn-glycerol 3-phosphate | - |
? | |
linoleoyl-CoA + sn-glycerol 3-phosphate | poor substrate | Rattus norvegicus Wistar | CoA + 1-linoleoyl-sn-glycerol 3-phosphate | - |
? | |
oleoyl-CoA + sn-glycerol 3-phosphate | poor substrate | Rattus norvegicus | CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
? | |
oleoyl-CoA + sn-glycerol 3-phosphate | poor substrate | Rattus norvegicus Wistar | CoA + 1-oleoyl-sn-glycerol 3-phosphate | - |
? | |
palmitoyl-CoA + sn-glycerol 3-phosphate | best acyl donor | Rattus norvegicus | CoA + 1-palmitoyl-sn-glycerol 3-phosphate | - |
? | |
palmitoyl-CoA + sn-glycerol 3-phosphate | best acyl donor | Rattus norvegicus Wistar | CoA + 1-palmitoyl-sn-glycerol 3-phosphate | - |
? | |
stearoyl-CoA + sn-glycerol 3-phosphate | - |
Rattus norvegicus | CoA + 1-stearoyl-sn-glycerol 3-phosphate | - |
? | |
stearoyl-CoA + sn-glycerol 3-phosphate | - |
Rattus norvegicus Wistar | CoA + 1-stearoyl-sn-glycerol 3-phosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.6 | 9 | both microsomal and mitochondrial enzymes exhibit a broad optimum | Rattus norvegicus |