Application | Comment | Organism |
---|---|---|
diagnostics | GART expression is associated with glioma grade and high GART protein expression might be related to poor outcome | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | silencing of GART expression by RNA interference | Homo sapiens |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
lometrexol | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P22102 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | enzyme immunohistochemic analysis in 70 cases of human gliomas and normal brain tissues, overview | Homo sapiens | - |
glioblastoma cell | - |
Homo sapiens | - |
glioma cell | the enzyme is frequently overexpressed in glioma, enzyme immunohistochemic analysis in 70 cases of human gliomas and normal brain tissues, overview | Homo sapiens | - |
H-4 cell | - |
Homo sapiens | - |
U87-MG cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
GART | - |
Homo sapiens |
glycinamide ribonucleotide formyl transferase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | transfecting cells with GART-siRNA suppresses proliferation and enhances temozolomide-induced apoptosis in glioma cells | Homo sapiens |
physiological function | glycinamide ribonucleotide formyl transferase is frequently overexpressed in glioma and critically regulates the proliferation of glioma cells | Homo sapiens |