Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | SecTRAPs (selenium compromised thioredoxin reductase-derived apoptotic proteins) can be formed from the selenoprotein thioredoxin reductase by targeting of its selenocysteine residue with electrophiles, or by its removal through C-terminal truncation. SecTRAPs are devoid of thioredoxin reductase activity but can induce rapid cell death in cultured cancer cell lines by a gain of function. Human and rat SecTRAPs induce cell death in human A549 and HeLa cells | Homo sapiens | |
additional information | SecTRAPs (selenium compromised thioredoxin reductase-derived apoptotic proteins) can be formed from the selenoprotein thioredoxin reductase by targeting of its selenocysteine residue with electrophiles, or by its removal through C-terminal truncation. SecTRAPs are devoid of thioredoxin reductase activity but can induce rapid cell death in cultured cancer cell lines by a gain of function. Human and rat SecTRAPs induce cell death in human A549 and HeLa cells | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | O89049 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
TrxR | - |
Homo sapiens |
TrxR1 | - |
Rattus norvegicus |