Inhibitors | Comment | Organism | Structure |
---|---|---|---|
auranofin | 5-10 nM, 50% inhibition, complete inhibition above 15 nM | Rattus norvegicus | |
gold acetate | 500 nM, 50% inhibition | Rattus norvegicus | |
gold sodium thiomalate | 500 nM, 50% inhibition | Rattus norvegicus | |
sodium aurothiosulfate | 100 nM, 50% inhibition | Rattus norvegicus | |
triphenyl phosphine gold chloride | 75 nM, 50% inhibition | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
5,5'-dithiobis(2-nitrobenzoic acid) + NADPH | - |
Rattus norvegicus | 2-nitro-5-thiobenzoate + NADP+ | - |
? | |
thioredoxin + NADP+ | - |
Rattus norvegicus | thioredoxin disulfide + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
thioredoxin reductase | - |
Rattus norvegicus |
TrxR1 | - |
Rattus norvegicus |