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Literature summary for 1.3.3.4 extracted from

  • Liang, L.; Yu, S.; Li, Q.; Wang, X.; Wang, D.; Xi, Z.
    Design, synthesis, and molecular simulation studies of N-phenyltetrahydroquinazolinones as protoporphyrinogen IX oxidase inhibitors (2021), Bioorg. Med. Chem., 39, 116165 .
    View publication on PubMed
Search for more literature for 1.3.3.4

Inhibitors

Inhibitors Comment Organism Structure
1-(allyloxy)-1-oxopropan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
1-(tert-butoxy)-1-oxopropan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
1-ethoxy-1-oxopropan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
1-oxo-1-(prop-2-yn-1-yloxy)propan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
2-(allyloxy)-2-oxoethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
2-(tert-butoxy)-2-oxoethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
2-chloro-N-(cyanomethyl)-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzenesulfonamide
-
 Nicotiana tabacum
2-ethoxy-2-oxoethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
2-oxo-2-(prop-2-yn-1-yloxy)ethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
allyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
bencarbazone
-
 Nicotiana tabacum
benzyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
bifenox
-
 Nicotiana tabacum
butafenacil
-
 Nicotiana tabacum
butyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
ethoxyfen-ethyl
-
 Nicotiana tabacum
ethyl ((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)alaninate
-
 Nicotiana tabacum
ethyl ((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)glycinate
-
 Nicotiana tabacum
ethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
fluazolate
-
 Nicotiana tabacum
flumioxazin
-
 Nicotiana tabacum
fluoroglycofen-ethyl
-
 Nicotiana tabacum
formesafen
-
 Nicotiana tabacum
halosafen
-
 Nicotiana tabacum
isopropyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
lactofen
-
 Nicotiana tabacum
methyl ((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)glycinate
-
 Nicotiana tabacum
methyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
profluazol
-
 Nicotiana tabacum
prop-2-yn-1-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
propyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate
-
 Nicotiana tabacum
saflufenacil
-
 Nicotiana tabacum
sulfentrazone
-
 Nicotiana tabacum
tert-butyl((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)glycinate
-
 Nicotiana tabacum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protoporphyrinogen IX + 3 O2 Nicotiana tabacum
-
 protoporphyrin IX + 3 H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Nicotiana tabacum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protoporphyrinogen IX + 3 O2
-
 Nicotiana tabacum protoporphyrin IX + 3 H2O2
-
 ?

Synonyms

Synonyms Comment Organism
PPO
-
 Nicotiana tabacum
protoporphyrinogen IX oxidase
-
 Nicotiana tabacum

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.000004
-
 1-(tert-butoxy)-1-oxopropan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000005
-
 2-(tert-butoxy)-2-oxoethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000005
-
 ethyl ((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)alaninate pH and temperature not specified in the publication Nicotiana tabacum
0.000006
-
 1-ethoxy-1-oxopropan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000006
-
 ethyl ((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)glycinate pH and temperature not specified in the publication Nicotiana tabacum
0.000007
-
 butyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000008
-
 propyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000009
-
 ethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.00001
-
 2-(allyloxy)-2-oxoethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.00001
-
 methyl ((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)glycinate pH and temperature not specified in the publication Nicotiana tabacum
0.000011
-
 1-(allyloxy)-1-oxopropan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000012
-
 1-oxo-1-(prop-2-yn-1-yloxy)propan-2-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000012
-
 isopropyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000013
-
 2-chloro-N-(cyanomethyl)-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzenesulfonamide pH and temperature not specified in the publication Nicotiana tabacum
0.000014
-
 2-oxo-2-(prop-2-yn-1-yloxy)ethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000014
-
 prop-2-yn-1-yl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000014
-
 tert-butyl((2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)phenyl)sulfonyl)glycinate pH and temperature not specified in the publication Nicotiana tabacum
0.000015
-
 benzyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000015
-
 methyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000019
-
 2-ethoxy-2-oxoethyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.00002
-
 allyl 2-chloro-4-fluoro-5-(4-oxo-5,6,7,8-tetrahydroquinazolin-3(4H)-yl)benzoate pH and temperature not specified in the publication Nicotiana tabacum
0.000046
-
 flumioxazin pH and temperature not specified in the publication Nicotiana tabacum