Cloned (Comment) | Organism |
---|---|
overexpression in Escherichia coli BL21 (DE3) Codon Plus RP cells | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(4-methyl)zymosterone + NADPH + H+ | Homo sapiens | cholesterol pathway | (4-methyl)zymosterol + NADP+ | - |
? | |
dihydrotestosterone + NADPH + H+ | Homo sapiens | steroid hormone pathway | 5alpha-androstane-3beta,17beta-diol + NADP+ | - |
? | |
progesterone + NADPH + H+ | Homo sapiens | steroid hormone pathway | 4-pregnen-3beta-ol-20-one + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P56937 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(4-methyl)zymosterone + NADPH + H+ | - |
Homo sapiens | (4-methyl)zymosterol + NADP+ | - |
? | |
(4-methyl)zymosterone + NADPH + H+ | cholesterol pathway | Homo sapiens | (4-methyl)zymosterol + NADP+ | - |
? | |
dihydrotestosterone + NADPH + H+ | - |
Homo sapiens | 5alpha-androstane-3beta,17beta-diol + NADP+ | - |
? | |
dihydrotestosterone + NADPH + H+ | steroid hormone pathway | Homo sapiens | 5alpha-androstane-3beta,17beta-diol + NADP+ | - |
? | |
progesterone + NADPH + H+ | - |
Homo sapiens | 4-pregnen-3beta-ol-20-one + NADP+ | - |
? | |
progesterone + NADPH + H+ | steroid hormone pathway | Homo sapiens | 4-pregnen-3beta-ol-20-one + NADP+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HSD17B7 | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | the enzyme is involved in the metabolism of steroid hormones and in the biosynthesis of cholesterol | Homo sapiens |