Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2S)-2'-methoxykurarinone | potent inhibitor of rat lens aldose reductase | Rattus norvegicus | |
(2S)-3beta,7,4'-trihydroxy-5-methoxy-8-(gamma,gamma-dimethylallyl)-flavanone | - |
Homo sapiens | |
(2S)-3beta,7,4'-trihydroxy-5-methoxy-8-(gamma,gamma-dimethylallyl)-flavanone | - |
Rattus norvegicus | |
(2S)-7,4'-dihydroxy-5-methoxy-8-(gamma,gamma-dimethylallyl)-flavanone | potent inhibitor of recombinant human aldose reductase | Homo sapiens | |
8-lavandulylkaempferol | potent inhibitor of recombinant human aldose reductase | Homo sapiens | |
8-lavandulylkaempferol | potent inhibitor of rat lens aldose reductase | Rattus norvegicus | |
desmethylanhydroicaritin | potent inhibitor of recombinant human aldose reductase | Homo sapiens | |
desmethylanhydroicaritin | potent inhibitor of rat lens aldose reductase | Rattus norvegicus | |
epalrestat | - |
Homo sapiens | |
kuraridin | potent inhibitor of recombinant human aldose reductase | Homo sapiens | |
kurarinol | potent inhibitor of rat lens aldose reductase | Rattus norvegicus | |
kurarinone | potent inhibitor of rat lens aldose reductase | Rattus norvegicus | |
kushenol E | potent inhibitor of recombinant human aldose reductase | Homo sapiens | |
kushenol E | potent inhibitor of rat lens aldose reductase | Rattus norvegicus | |
quercetin | potent inhibitor of recombinant human aldose reductase | Homo sapiens | |
quercetin | potent inhibitor of rat lens aldose reductase | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lens | - |
Rattus norvegicus | - |
Synonyms | Comment | Organism |
---|---|---|
aldose reductase | - |
Homo sapiens |
aldose reductase | - |
Rattus norvegicus |
RLAR | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00027 | - |
- |
Homo sapiens | kuraridin | |
0.00028 | - |
- |
Homo sapiens | epalrestat | |
0.00037 | - |
- |
Homo sapiens | (2S)-7,4'-dihydroxy-5-methoxy-8-(gamma,gamma-dimethylallyl)-flavanone | |
0.00045 | - |
- |
Homo sapiens | desmethylanhydroicaritin | |
0.00079 | - |
- |
Homo sapiens | 8-lavandulylkaempferol | |
0.00085 | - |
- |
Homo sapiens | kushenol E | |
0.00095 | - |
- |
Rattus norvegicus | desmethylanhydroicaritin | |
0.00213 | - |
- |
Rattus norvegicus | kurarinol | |
0.00254 | - |
- |
Homo sapiens | quercetin | |
0.00299 | - |
- |
Rattus norvegicus | kurarinone | |
0.00363 | - |
- |
Rattus norvegicus | (2S)-3beta,7,4'-trihydroxy-5-methoxy-8-(gamma,gamma-dimethylallyl)-flavanone | |
0.00377 | - |
- |
Rattus norvegicus | (2S)-2'-methoxykurarinone | |
0.0038 | - |
- |
Rattus norvegicus | 8-lavandulylkaempferol | |
0.00773 | - |
- |
Rattus norvegicus | quercetin | |
0.00774 | - |
- |
Rattus norvegicus | kushenol E |