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show all sequences of 1.1.1.173

Identification and characterization of 2-keto-3-deoxy-L-rhamnonate dehydrogenase belonging to the MDR superfamily from the thermoacidophilic bacterium Sulfobacillus thermosulfidooxidans: implications to L-rhamnose metabolism in archaea

Bae, J.; Kim, S.M.; Lee, S.B.; Extremophiles 19, 469-478 (2015)

Data extracted from this reference:

Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Sulfobacillus thermosulfidooxidans
-
-
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.11
-
substrate L-rhamnose, cosubstrate NADP+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
1.22
-
substrate L-mannose, cosubstrate NAD+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
22
-
substrate L-lyxose, cosubstrate NAD+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
33
-
substrate L-rhamnose, cosubstrate NAD+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-lyxose + NAD+
-
733813
Sulfobacillus thermosulfidooxidans
? + NADH
-
-
-
?
L-mannose + NAD+
-
733813
Sulfobacillus thermosulfidooxidans
? + NADH
-
-
-
?
L-rhamnose + NAD+
-
733813
Sulfobacillus thermosulfidooxidans
L-rhamno-1,4-lactone + NADH
-
-
-
?
L-rhamnose + NADP+
-
733813
Sulfobacillus thermosulfidooxidans
L-rhamno-1,4-lactone + NADPH
-
-
-
?
additional information
no substrates are: D-glucose, D-mannose, D-galactose, D-fructose, D-xylose, D-fucose, D-arabinose, D-lyxose, D-ribose, D-fucose, L-fucose, L-xylose, L-arabinose, L-sorbose, sorbitol, mannitol, xylitol, 2,3-butanediol, 2-dehydro-3-deoxy-L-rhamnonate, and L-rhamnonate
733813
Sulfobacillus thermosulfidooxidans
?
-
-
-
-
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
60
-
-
Sulfobacillus thermosulfidooxidans
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.5
-
-
Sulfobacillus thermosulfidooxidans
Cofactor
Cofactor
Commentary
Organism
Structure
NAD+
NAD+ is preferred over NADP+
Sulfobacillus thermosulfidooxidans
NADP+
about 30fold less activity than with NAD+
Sulfobacillus thermosulfidooxidans
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NAD+
NAD+ is preferred over NADP+
Sulfobacillus thermosulfidooxidans
NADP+
about 30fold less activity than with NAD+
Sulfobacillus thermosulfidooxidans
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
1.11
-
substrate L-rhamnose, cosubstrate NADP+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
1.22
-
substrate L-mannose, cosubstrate NAD+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
22
-
substrate L-lyxose, cosubstrate NAD+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
33
-
substrate L-rhamnose, cosubstrate NAD+, pH 9.5, 50°C
Sulfobacillus thermosulfidooxidans
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-lyxose + NAD+
-
733813
Sulfobacillus thermosulfidooxidans
? + NADH
-
-
-
?
L-mannose + NAD+
-
733813
Sulfobacillus thermosulfidooxidans
? + NADH
-
-
-
?
L-rhamnose + NAD+
-
733813
Sulfobacillus thermosulfidooxidans
L-rhamno-1,4-lactone + NADH
-
-
-
?
L-rhamnose + NADP+
-
733813
Sulfobacillus thermosulfidooxidans
L-rhamno-1,4-lactone + NADPH
-
-
-
?
additional information
no substrates are: D-glucose, D-mannose, D-galactose, D-fructose, D-xylose, D-fucose, D-arabinose, D-lyxose, D-ribose, D-fucose, L-fucose, L-xylose, L-arabinose, L-sorbose, sorbitol, mannitol, xylitol, 2,3-butanediol, 2-dehydro-3-deoxy-L-rhamnonate, and L-rhamnonate
733813
Sulfobacillus thermosulfidooxidans
?
-
-
-
-
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
60
-
-
Sulfobacillus thermosulfidooxidans
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
9.5
-
-
Sulfobacillus thermosulfidooxidans
Other publictions for EC 1.1.1.173
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
733813
Bae
Identification and characteriz ...
Sulfobacillus thermosulfidooxidans
Extremophiles
19
469-478
2015
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5
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4
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5
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1
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1
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686697
Koivistoinen
Identification in the yeast Pi ...
Scheffersomyces stipitis, Scheffersomyces stipitis NRC5568
FEBS J.
275
2482-2488
2008
1
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1
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1
4
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1
2
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6
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1
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1
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10
1
1
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1
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3
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1
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1
3
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1
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4
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1
2
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1
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1
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10
1
1
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1
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687737
Watanabe
Eukaryotic and bacterial gene ...
Debaryomyces hansenii, Debaryomyces hansenii NBRC0083, Scheffersomyces stipitis
J. Biol. Chem.
283
20372-20382
2008
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2
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2
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1
3
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10
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2
2
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3
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3
1
2
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2
2
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4
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2
4
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2
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1
3
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2
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3
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3
1
2
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2
2
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286118
Mostad
The stereospecificity of hydro ...
Aureobasidium pullulans
Biochem. Biophys. Res. Commun.
233
681-686
1997
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1
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1
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347736
Twerdochlib
-
L-Rhamnose metabolism in Pichi ...
Scheffersomyces stipitis
Can. J. Microbiol.
40
896-902
1994
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2
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1
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2
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2
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2
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347735
Pardo
-
Pichia stipitis L-rhamnose deh ...
Scheffersomyces stipitis
Can. J. Microbiol.
38
417-422
1992
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1
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1
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1
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347732
Pittner
-
The application of immobilized ...
Aureobasidium pullulans
Appl. Biochem. Biotechnol.
16
15-24
1987
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2
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1
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1
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1
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1
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1
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2
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2
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1
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1
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1
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1
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347733
Rigo
L-Rhamnose dehydrogenase of pu ...
Aureobasidium pullulans
Biochim. Biophys. Acta
445
286-293
1976
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6
2
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1
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1
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1
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1
1
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1
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2
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6
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2
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1
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1
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1
1
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1
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