Information on EC 5.1.1.12 - ornithine racemase

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The expected taxonomic range for this enzyme is: Acetoanaerobium sticklandii

EC NUMBER
COMMENTARY hide
5.1.1.12
-
RECOMMENDED NAME
GeneOntology No.
ornithine racemase
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
L-ornithine = D-ornithine
show the reaction diagram
-
-
-
-
REACTION TYPE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
racemization
-
-
-
-
PATHWAY
BRENDA Link
KEGG Link
MetaCyc Link
D-Arginine and D-ornithine metabolism
-
-
L-ornithine degradation II (Stickland reaction)
-
-
urea cycle
-
-
SYSTEMATIC NAME
IUBMB Comments
ornithine racemase
-
CAS REGISTRY NUMBER
COMMENTARY hide
62213-28-9
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
metabolism
catalyzes the first step in the ornithine fermentation pathway
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
D-alanine
L-alanine
show the reaction diagram
conversion is lower than 10% compared to conversion of L-ornithine
-
-
r
L-asparagine
D-asparagine
show the reaction diagram
conversion is lower than 10% compared to conversion of L-ornithine
-
-
r
L-Ornithine
D-Ornithine
show the reaction diagram
L-serine
D-serine
show the reaction diagram
conversion is 10% compared to conversion of L-ornithine
-
-
r
NATURAL SUBSTRATES
NATURAL PRODUCTS
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
L-Ornithine
D-Ornithine
show the reaction diagram
C1FW08
-
-
-
r
COFACTOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
pyridoxal 5'-phosphate
-
KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.52 - 0.77
L-ornithine
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
980 - 1660
L-ornithine
kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
3192
L-ornithine
Clostridium sticklandii
C1FW08
-
192
SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
21500
2 * 21500, gel filtration
46800
-
2 * 46800, SDS-PAGE
92000
-
gel filtration
SUBUNITS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
dimer
-
2 * 46800, SDS-PAGE
homodimer
2 * 21500, gel filtration
Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expressed His-tagged recombinant protein
Show AA Sequence (144 entries)
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