Information on EC 4.2.3.115 - alpha-terpinene synthase

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The expected taxonomic range for this enzyme is: Dysphania ambrosioides

EC NUMBER
COMMENTARY hide
4.2.3.115
-
RECOMMENDED NAME
GeneOntology No.
alpha-terpinene synthase
-
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranyl diphosphate = alpha-terpinene + diphosphate
show the reaction diagram
SYSTEMATIC NAME
IUBMB Comments
geranyl-diphosphate diphosphate-lyase (cyclizing, alpha-terpinene-forming)
The enzyme has been characterized from Dysphania ambrosioides (American wormseed). Requires Mg2+. Mn2+ is less effective. The enzyme will also use (3R)-linalyl diphosphate. The reaction involves a 1,2-hydride shift. The 1-pro-S hydrogen of geranyl diphosphate is lost.
CAS REGISTRY NUMBER
COMMENTARY hide
155807-66-2
-
ORGANISM
COMMENTARY hide
LITERATURE
UNIPROT
SEQUENCE DB
SOURCE
SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
geranyl diphosphate
alpha-terpinene + diphosphate
show the reaction diagram
-
-
the isomerization-cyclization involves a 1,2-hydride shift in the terpinyl cation to the terpin-4-yl-cation
-
?
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
LOCALIZATION
ORGANISM
UNIPROT
COMMENTARY hide
GeneOntology No.
LITERATURE
SOURCE