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Disease on EC 3.5.2.17 - hydroxyisourate hydrolase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Abortion, Spontaneous
Proteomic analysis on the alteration of protein expression in the placental villous tissue of early pregnancy loss.
Acquired Immunodeficiency Syndrome
Micronutrient levels in HIV-1-infected children.
MicroRNA regulation of Transthyretin in trophoblast differentiation and Intra-Uterine Growth Restriction.
Nutritional status in patients with HIV infection and AIDS.
The acute-phase protein response to human immunodeficiency virus infection in human subjects.
Acute Kidney Injury
Gene Microarray Integrated with High-Throughput Proteomics for the Discovery of Transthyretin in Rhabdomyolysis-Induced Acute Kidney Injury.
Adenocarcinoma
Identification and verification of transthyretin as a potential biomarker for pancreatic ductal adenocarcinoma.
Immunohistochemical Assessment of Transthyretin Association with Colorectal Adenocarcinoma.
Serum biomarker panels for the diagnosis of gastric adenocarcinoma.
Adenocarcinoma of Lung
CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain.
Adenoma
Detection of colorectal adenoma and cancer based on transthyretin and C3a-desArg serum levels.
Albuminuria
Albumin/creatinine (uACR) and protein/creatinine (uPCR) ratios in spot urine samples can be used to evaluate albuminuria and proteinuria in hereditary transthyretin amyloidosis patients.
Alzheimer Disease
A highly sensitive fluorescent probe that quantifies transthyretin in human plasma as an early diagnostic tool of Alzheimer's disease.
A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation.
A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition.
Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC.
An aberrant protein complex in CSF as a biomarker of Alzheimer disease.
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Apolipoprotein E, transthyretin and actin in the CSF of Alzheimer's patients: relation with the senile plaques and cytoskeleton biochemistry.
Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families.
Asymmetric expression patterns of brain transthyretin in normal mice and a transgenic mouse model of Alzheimer's disease.
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.
Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, A? Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.
Cerebrospinal fluid transthyretin: aging and late onset Alzheimer's disease.
Chromolaena odorata (Siam weed): A natural reservoir of bioactive compounds with potent anti-fibrillogenic, antioxidative, and cytocompatible properties.
Concurrent cardiac transthyretin and brain ? amyloid accumulation among the older adults: The Hisayama study.
Copper mediated amyloid-? binding to Transthyretin.
Crystal and molecular structure of piceatannol; scavenging features of resveratrol and piceatannol on hydroxyl and peroxyl radicals and docking with transthyretin.
Differential post-translational modifications of transthyretin in Alzheimer's disease: A study of the cerebral spinal fluid.
Distinct transthyretin oxidation isoform profile in spinal fluid from patients with Alzheimer's disease and mild cognitive impairment.
Effect of Red Wine Polyphenols on the Expression of Transthyretin in Murine Choroid Plexus.
Effects on transthyretin in plasma and cerebrospinal fluid by DHA-rich n - 3 fatty acid supplementation in patients with Alzheimer's disease: the OmegAD study.
Elevated risks for amyotrophic lateral sclerosis and blood disorders in Ashkenazi schizophrenic pedigrees suggest new candidate genes in schizophrenia.
Evidence for synergistic action of transthyretin and IGF-I over the IGF-I receptor.
Exploring the Physiological Role of Transthyretin in Glucose Metabolism in the Liver.
Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins.
Gender-Dependent Transthyretin Modulation of Brain Amyloid-? Levels: Evidence from a Mouse Model of Alzheimer's Disease.
Human Serum Transthyretin Levels Correlate Inversely with Alzheimer's Disease.
Immunoglobulin light chains, glycosaminoglycans, and amyloid.
Increased protein glycation in cerebrospinal fluid of Alzheimer's disease.
Isolated atrial amyloidosis and the importance of molecular classification.
Mechanisms of transthyretin inhibition of ?-amyloid aggregation in vitro.
Mitochondria-targeted catalase reduces abnormal APP processing, amyloid ? production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension.
Molecular biology of brain aging and neurodegenerative disorders.
Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?
Neuroprotection in early stages of Alzheimer's disease is promoted by transthyretin angiogenic properties.
Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization.
Plasma transthyretin as a candidate marker for Alzheimer's disease.
Possible involvement of transthyretin in hippocampal beta-amyloid burden and learning behaviors in a mouse model of Alzheimer's disease (TgCRND8).
Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions.
Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia.
Radiofrequency Fields, Transthyretin, and Alzheimer's Disease.
Rare Genetic Variants of the Transthyretin Gene Are Associated with Alzheimer's Disease in Han Chinese.
Serum and cerebrospinal fluid levels of transthyretin in Lewy body disorders with and without dementia.
Serum levels of proteins involved in amyloid-? clearance are related to cognitive decline and neuroimaging changes in mild cognitive impairment.
Serum transthyretin and risk of cognitive decline and dementia: 22-year longitudinal study.
Stability of the transthyretin molecule as a key factor in the interaction with a-beta peptide--relevance in Alzheimer's disease.
Sustained choroid plexus function in human elderly and Alzheimer's disease patients.
Targeted Nuclear Imaging Probes for Cardiac Amyloidosis.
The effects of age, apolipoprotein E phenotype and gender on the concentration of amyloid-beta (A beta) 40, A beta 4242, apolipoprotein E and transthyretin in human cerebrospinal fluid.
The Function of Transthyretin Complexes with Metallothionein in Alzheimer's Disease.
The protease activity of transthyretin reverses the effect of pH on the amyloid-? protein/heparan sulfate proteoglycan interaction: a biochromatographic study.
The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.
The Ultrastructure of Tissue Damage by Amyloid Fibrils.
Transthyretin accelerates vascular Abeta deposition in a mouse model of Alzheimer's disease.
Transthyretin and Alzheimer's disease: where in the brain?
Transthyretin and the brain re-visited: is neuronal synthesis of transthyretin protective in Alzheimer's disease?
Transthyretin as a potential CSF biomarker for Alzheimer's disease and dementia with Lewy bodies: effects of treatment with cholinesterase inhibitors.
Transthyretin binding to A-Beta peptide - Impact on A-Beta fibrillogenesis and toxicity.
Transthyretin gene in Alzheimer's disease patients.
Transthyretin inhibition of amyloid beta aggregation and toxicity.
Transthyretin neuroprotection in Alzheimer's disease is dependent on proteolysis.
Transthyretin stability is critical in assisting beta amyloid clearance- Relevance of transthyretin stabilization in Alzheimer's disease.
Transthyretin stabilization by iododiflunisal promotes amyloid-? peptide clearance, decreases its deposition, and ameliorates cognitive deficits in an Alzheimer's disease mouse model.
Undiscovered Roles for Transthyretin: From a Transporter Protein to a New Therapeutic Target for Alzheimer's Disease.
[Identification of transthyretin posttranslational modifications 1n human blood using mass-spectrometric methods].
[Transthyretin levels in serum and cerebrospinal fluid sustain the nutrio-viral hypothesis of the Cuban epidemic neuropathy]
Amyloid Neuropathies
A comprehensive safety profile of tafamidis in patients with transthyretin amyloid polyneuropathy.
A novel transthyretin mutation V32A in a Chinese man with late-onset amyloid polyneuropathy.
Amyloid and peripheral nervous system disease.
Amyloid Neuropathy with Transthyretin Mutations: Overview and Unique Ala97Ser in Taiwan.
Amyloid Polyneuropathy and Myocardial Amyloidosis 10 Years after Domino Liver Transplantation from a Patient with a Transthyretin Ser50Arg Mutation.
Amyloid Polyneuropathy Caused By Wild-Type Transthyretin.
Amyloid polyneuropathy in two German-American families: a new transthyretin variant (Val 107).
Amyloid polyneuropathy with transthyretin Arg50 in a Japanese case from Osaka.
An amyotrophic lateral sclerosis-like syndrome revealing an amyloid polyneuropathy associated with a novel transthyretin mutation.
Applying an artificial neural network model for developing a severity score for patients with hereditary amyloid polyneuropathy.
Autonomic dysfunction in peripheral nerve disease.
C1q ablation exacerbates amyloid deposition: A study in a transgenic mouse model of ATTRV30M amyloid neuropathy.
Cardiac phenotype and clinical outcome of familial amyloid polyneuropathy associated with transthyretin alanine 60 variant.
Clinical presentations and skin denervation in amyloid neuropathy due to transthyretin Ala97Ser.
Coexistence of familial transthyretin amyloidosis ATTR Val30Met and spinocerebellar ataxia type 1 in a Japanese family--a follow-up autopsy report.
Contribution of wild-type transthyretin to hereditary peripheral nerve amyloid.
Cutaneous Manifestations of Familial Transthyretin Amyloid Polyneuropathy.
Diagnosis of amyloid neuropathy.
Diagnosis of small fiber neuropathy: A comparative study of five neurophysiological tests.
Diflunisal compassive use in transthyretin hereditary amyloid polyneuropathy: report of a first Spanish experience.
Early intervention with tafamidis provides long-term (5.5-year) delay of neurologic progression in transthyretin hereditary amyloid polyneuropathy.
Early skin denervation in hereditary and iatrogenic transthyretin amyloid neuropathy.
Endoplasmic reticulum stress associated with extracellular aggregates. Evidence from transthyretin deposition in familial amyloid polyneuropathy.
Epidemiological and clinical characteristics of persons with transthyretin hereditary amyloid polyneuropathy: a global synthesis of 532 cases.
Epidemiological and clinical characteristics of symptomatic hereditary transthyretin amyloid polyneuropathy: a global case series.
Estimating the annual economic burden for the management of patients with transthyretin amyloid polyneuropathy in Spain.
Expression of a synthetic gene encoding human transthyretin in Escherichia coli.
Familial amyloid polyneuropathy: alanine-for-threonine substitution in the transthyretin (prealbumin) molecule.
Feasibility of assessing progression of transthyretin amyloid polyneuropathy using nerve conduction studies: Findings from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Follow-up in transthyretin familial amyloid polyneuropathy: Useful investigations.
Genetic study of transthyretin amyloid neuropathies: carrier risks among French and Portuguese families.
Genotype-phenotype correlation and course of transthyretin familial amyloid polyneuropathies in France.
Global epidemiology of transthyretin hereditary amyloid polyneuropathy: a systematic review.
Hard to swallow: atypical transthyretin amyloid neuropathy mistaken for CIDP.
Hereditary amyloid neuropathy by transthyretin Val107 mutation in a patient of African origin.
Hereditary neuropathies: An update.
Historical overview of analytical methods for the measurement of transthyretin.
Iatrogenic amyloid polyneuropathy after domino liver transplantation.
Identification of a new transthyretin variant (Ile49) in familial amyloidotic polyneuropathy using electrospray ionization mass spectrometry and nonisotopic RNase cleavage assay.
Immunoassay for transthyretin variants associated with amyloid neuropathy.
Impact of Non-Cardiac Clinicopathologic Characteristics on Survival in Transthyretin Amyloid Polyneuropathy.
Influence of baseline neurologic severity on disease progression and the associated disease-modifying effects of tafamidis in patients with transthyretin amyloid polyneuropathy.
Late-onset Transthyretin (TTR)-familial Amyloid Polyneuropathy (FAP) with a Long Disease Duration from Non-endemic Areas in Japan.
Long-term safety and efficacy of tafamidis for the treatment of hereditary transthyretin amyloid polyneuropathy: results up to 6 years.
Low erythropoietin production in familial amyloidosis TTR V30M is not related with renal congophilic amyloid deposition. A clinicopathologic study of twelve cases.
Metabolic turn over of amyloid fibrils and post-treatment regression of amyloid deposits in systemic amyloidosis with polyneuropathy.
Molecular genetics of peripheral neuropathies.
Neurophysiological techniques to detect early small-fiber dysfunction in transthyretin amyloid polyneuropathy.
New structural information and update on liver transplantation in transthyretin-associated amyloidosis. Report from the 4th International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders & the 3rd International Workshop on Liver Transplantation in Familial Amyloid Polyneuropathy, Umeå Sweden, June 1999.
New transthyretin mutation V28M in a Portuguese kindred with amyloid polyneuropathy.
Paraproteinemias and Peripheral Nerve Disease.
Parent-of-origin effect in transthyretin related amyloid polyneuropathy.
Parenteral nutrition improves nutritional status, autonomic symptoms and quality of life in transthyretin amyloid polyneuropathy.
Patient and family experience with transthyretin amyloid cardiomyopathy (ATTR-CM) and polyneuropathy (ATTR-PN) amyloidosis: results of two focus groups.
PEL: an unbiased method for estimating age-dependent genetic disease risk from pedigree data unselected for family history.
Phenotypes of Late-Onset Transthyretin Amyloid Neuropathy: A Diagnostic Challenge.
Poor outcome after liver transplantation for transthyretin amyloid neuropathy in a family with an Ala36Pro transthyretin mutation: case report.
Population pharmacokinetic modelling and simulation of tafamidis in healthy subjects and patients with transthyretin amyloidosis.
Prevalence of hereditary transthyretin amyloid polyneuropathy in idiopathic progressive neuropathy in conurban areas.
Progression of transthyretin amyloid neuropathy after liver transplantation.
Quantified sensory abnormalities in early genetically verified transthyretin amyloid polyneuropathy.
Quantitative sensation and autonomic test abnormalities in transthyretin amyloidosis polyneuropathy.
Rapidly progressive amyloid polyneuropathy associated with a novel variant transthyretin serine 25.
Refine penetrance estimates in the main pathogenic variants of transthyretin hereditary (familial) amyloid polyneuropathy (TTR-FAP) using a new non-parametric approach (NPSE).
Retrospective study of a TTR FAP cohort to modify NIS+7 for therapeutic trials.
Sudomotor innervation in transthyretin amyloid neuropathy: Pathology and functional correlates.
Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease.
Systemic amyloidosis in laying Japanese quail.
Tafamidis for a Transplant Patient with Transthyretin Amyloid Polyneuropathy.
The clinical and biochemical spectrum of hereditary amyloidosis.
The liver in systemic amyloidosis: insights from 123I serum amyloid P component scintigraphy in 484 patients.
Transthyretin amyloid neuropathy has earlier neural involvement but better prognosis than primary amyloid counterpart: an answer to the paradox?
Transthyretin Amyloid Neuropathy: The Schwann Cell Hypothesis.
Transthyretin amyloid polyneuropathies mimicking a demyelinating polyneuropathy.
Transthyretin amyloidosis presenting with multifocal demyelinating mononeuropathies.
Transthyretin gene mutations in British and French patients with amyloid neuropathy.
Transthyretin V122I amyloidosis with clinical and histological evidence of amyloid neuropathy and myopathy.
Transthyretin Val 107 in a Japanese patient with familial amyloid polyneuropathy.
Treatment of hereditary and acquired forms of transthyretin amyloidosis in the era of personalized medicine: the role of randomized controlled trials.
Unravelling the colourful tapestry of hereditary transthyretin amyloid polyneuropathy in Poland.
[Aged onset of amyloidosis caused by transthyretin gene mutations]
[Amyloid neuropathy resulting from an unknown protein.]
[Amyloidoses].
[Autonomic peripheral neuropathy].
[Ocular involvement in familial amyloid polyneuropathy].
[Transthyretin familial amyloid polyneuropathy].
[Two elderly cases of transthyretin amyloid polyneuropathy without a family history].
Amyloid Neuropathies, Familial
"Red-flag" symptom clusters in transthyretin familial amyloid polyneuropathy.
1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy.
A case of familial amyloid polyneuropathy (FAP ATTR Ile107Val) with proximal muscle weakness in the lower extremities.
A case of familial amyloid polyneuropathy due to Phe33Val TTR with vitreous involvement as the initial manifestation.
A case of familial amyloid polyneuropathy homozygous for the transthyretin Val30Met gene with motor-dominant sensorimotor polyneuropathy and unusual sural nerve pathological findings.
A case of hereditary amyloidosis transthyretin variant Met 30 with amyloid cardiomyopathy, less polyneuropathy, and the presence of giant cells.
A European family with histidine 58 transthyretin mutation in familial amyloid polyneuropathy.
A homozygote case of familial amyloid polyneuropathy amyloidgenic transthyretin Val30Met in a non-endemic area.
A look into amyloid formation by transthyretin: aggregation pathway and a novel kinetic model.
A low amyloidogenic E61K transthyretin mutation may cause familial amyloid polyneuropathy.
A Missense Variant p.Ala117Ser in the Transthyretin Gene of a Han Chinese Family with Familial Amyloid Polyneuropathy.
A new mutant transthyretin (Arg 10) associated with familial amyloid polyneuropathy.
A new prion disease: relationship with central and peripheral amyloidoses.
A new transthyretin variant (Ser 24) associated with familial amyloid polyneuropathy.
A novel transthyretin variant p.H110D (H90D) as a cause of familial amyloid polyneuropathy in a large Irish kindred.
A peripheral pathway to restless legs syndrome? Clues from familial amyloid polyneuropathy.
A prospective, observational study of patients with uncommon distal symmetric painful small-fiber neuropathy.
A selective transthyretin-adsorption column for the treatment of patients with familial amyloid polyneuropathy.
A woman with a rare p.Glu74Gly transthyretin mutation presenting exclusively with a rapidly progressive neuropathy: a case report.
ABO-incompatible auxiliary partial orthotopic liver transplant for late-onset familial amyloid polyneuropathy.
Ala97Ser mutation is common among ethnic Chinese Malaysians with transthyretin familial amyloid polyneuropathy.
Alanine-to-threonine substitutions and amyloid diseases: Butyrylcholinesterase as a case study.
Ambulatory Medicines Cost With Transthyretin Familial Amyloid Polyneuropathy In Portugal.
Amyloid fibril protein in familial amyloidosis with cranial neuropathy and corneal lattice dystrophy (FAP type IV) is related to transthyretin.
Amyloidogenic transthyretin Val30Met homozygote showing unusually early-onset familial amyloid polyneuropathy.
An aggressive form of familial amyloid polyneuropathy caused by a Glu54Gly mutation in the transthyretin gene.
An Isolated Case of Late-onset Amyloidogenic Transthyretin Type Familial Amyloid Polyneuropathy Associated with a Mutant Transthyretin Substituting Methionine for Valine at Position 30 Showing Latent Progressive Cardiac Involvement Confirmed by Serial Annual Electrocardiograms.
Annual electrocardiograms consistent with silent progression of cardiac involvement in sporadic familial amyloid polyneuropathy: a case report.
Arrhythmia--a pitfall in tests of cardiac autonomic function after liver transplantation for familial amyloidotic polyneuropathy: a long-term follow-up of Swedish patients.
Assessment of autonomic innervation of the foot in familial amyloid polyneuropathy.
Asymptomatic homozygous gene carrier in a family with type I familial amyloid polyneuropathy.
Author response: Natural history and survival in stage 1 Val30Met transthyretin familial amyloid polyneuropathy.
Autonomic involvement in hereditary transthyretin amyloidosis (hATTR amyloidosis).
Autosomal-dominant transthyretin (TTR)-related amyloidosis is not a frequent CMT2 neuropathy "in disguise".
Baerveldt glaucoma drainage implant surgery for secondary glaucoma in patients with transthyretin-related familial amyloid polyneuropathy.
Baseline disease characteristics in Brazilian patients enrolled in Transthyretin Amyloidosis Outcome Survey (THAOS).
Binding and stabilization of transthyretin by curcumin.
Biophysical characterization and modulation of Transthyretin Ala97Ser.
Birth of two healthy females after preimplantation genetic diagnosis for familial amyloid polyneuropathy.
Brazilian consensus for diagnosis, management and treatment of transthyretin familial amyloid polyneuropathy.
C1QA and C1QC modify age-at-onset in familial amyloid polyneuropathy patients.
Cardiac amyloid in patients with familial amyloid polyneuropathy consists of abundant wild-type transthyretin.
Cardiac and peripheral vasomotor autonomic functions in late-onset transthyretin Val30Met familial amyloid polyneuropathy.
Cardiac phenotype and clinical outcome of familial amyloid polyneuropathy associated with transthyretin alanine 60 variant.
Cardiac sympathetic denervation in familial amyloid polyneuropathy assessed by iodine-123 metaiodobenzylguanidine scintigraphy and heart rate variability.
Cause of death analysis and temporal trends in survival after liver transplantation for transthyretin familial amyloid polyneuropathy.
Changes in renal function in patients with familial amyloid polyneuropathy treated with orthotopic liver transplantation.
Characterisation and management of vitreous and nerve amyloid in familial amyloid polyneuropathy due to variant transthyretin, Phe33Val.
Characteristics of Patients with Hereditary Transthyretin Amyloidosis and an Evaluation of the Safety of Tafamidis Meglumine in Japan: An Interim Analysis of an All-case Postmarketing Surveillance.
Characterization of a transthyretin-related amyloid fibril protein from cerebral amyloid angiopathy in type I familial amyloid polyneuropathy.
Characterization of Pain in Familial Amyloid Polyneuropathy.
Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation.
Characterizing the High Disease Burden of Transthyretin Amyloidosis for Patients and Caregivers.
Clinical and biochemical outcome of hepatorenal transplantation for hereditary systemic amyloidosis associated with apolipoprotein AI Gly26Arg.
Clinical and genetic findings in eight Israeli patients with transthyretin-associated familial amyloid polyneuropathy.
Clinical and pathological findings in familial amyloid polyneuropathy caused by a transthyretin E61K mutation.
Clinical and pathological studies of cardiac amyloidosis in transthyretin type familial amyloid polyneuropathy.
Clinical features of familial amyloid polyneuropathy carrying transthyretin mutations in four Chinese kindreds.
Clinical features of TTR-FAP in Portugal.
Clinical measures in transthyretin familial amyloid polyneuropathy.
Clinical presentations and skin denervation in amyloid neuropathy due to transthyretin Ala97Ser.
Clinicopathological correlations of sural nerve biopsies in TTR Val30Met familial amyloid polyneuropathy.
Coexistence of transthyretin familial amyloid polyneuropathy and hereditary neuropathy with liability to pressure palsy.
Comparison Between 99mTc-Diphosphonate Imaging and MRI With Late Gadolinium Enhancement in Evaluating Cardiac Involvement in Patients With Transthyretin Familial Amyloid Polyneuropathy.
Comparison of lethal and nonlethal transthyretin variants and their relationship to amyloid disease.
Contributions of Animal Models to the Mechanisms and Therapies of Transthyretin Amyloidosis.
Corneal sub-basal whorl-like nerve plexus: a landmark for early and follow-up evaluation in transthyretin familial amyloid polyneuropathy.
Correction to: Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm.
Curcumin could reduce the monomer of TTR with Tyr114Cys mutation via autophagy in cell model of familial amyloid polyneuropathy.
Current and Future Treatment Approaches in Transthyretin Familial Amyloid Polyneuropathy.
Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy.
Deposition and passage of transthyretin through the blood-nerve barrier in recipients of familial amyloid polyneuropathy livers.
Design and Rationale of the Phase 3 ATTR-ACT Clinical Trial (Tafamidis in Transthyretin Cardiomyopathy Clinical Trial).
Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening.
Diagnosis and management of sensory polyneuropathy.
Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm.
Diagnosis of sporadic transthyretin Val30Met familial amyloid polyneuropathy: a practical analysis.
Diagnostic hallmarks and pitfalls in late-onset progressive transthyretin-related amyloid-neuropathy.
Diagnostic pitfalls in sporadic transthyretin familial amyloid polyneuropathy (TTR-FAP).
Diffuse metabolic changes in the brain of patients with familial amyloid polyneuropathy. A proton MRSI study.
Diflunisal stabilizes familial amyloid polyneuropathy-associated transthyretin variant tetramers in serum against dissociation required for amyloidogenesis.
Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
Distinct characteristics of amyloid deposits in early- and late-onset transthyretin Val30Met familial amyloid polyneuropathy.
Domino liver transplantation: a practical option in the face of the organ shortage.
Early detection of sympathetic myocardial denervation in patients with familial amyloid polyneuropathy type I.
Early diagnosis in patients with transthyretin familial amyloid polyneuropathy: A comparative study.
Early intervention with tafamidis provides long-term (5.5-year) delay of neurologic progression in transthyretin hereditary amyloid polyneuropathy.
Editors' note: Natural history and survival in stage 1 Val30Met transthyretin familial amyloid polyneuropathy.
Effect on disability and safety of Tafamidis in late onset of Met30 transthyretin familial amyloid polyneuropathy.
Effects of tafamidis treatment on transthyretin (TTR) stabilization, efficacy, and safety in Japanese patients with familial amyloid polyneuropathy (TTR-FAP) with Val30Met and non-Varl30Met: A phase III, open-label study.
Efficiency of silencing RNA for removal of transthyretin V30M in a TTR leptomeningeal animal model.
Electromyographic findings in transthyretin (TTR)-related familial amyloid polyneuropathy (FAP).
Electrophysiological features of familial amyloid polyneuropathy in endemic area.
Electrophysiological features of late-onset transthyretin Met30 familial amyloid polyneuropathy unrelated to endemic foci.
Electrophysiological parameters that contribute to the pathogenesis of familial amyloid polyneuropathy caused by transthyretin mutations.
Endoplasmic reticulum stress associated with extracellular aggregates. Evidence from transthyretin deposition in familial amyloid polyneuropathy.
Endoscopic Findings of Small-Bowel Lesions in Familial Amyloid Polyneuropathy: A Case Report.
Epidemiology of Transthyretin Familial Amyloid Polyneuropathy in Portugal: A Nationwide Study.
Epidemiology of transthyretin-associated familial amyloid polyneuropathy in the Majorcan area: Son Llàtzer Hospital descriptive study.
Estimating the global prevalence of transthyretin familial amyloid polyneuropathy.
Evaluating the binding selectivity of transthyretin amyloid fibril inhibitors in blood plasma.
Evaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells.
Extended phenotype in the transthyretin Tyr77 familial amyloid polyneuropathy.
Extremely Early Onset Transthyretin Familial Amyloid Polyneuropathy with a Leu55Pro Mutation: A Pediatric Case Report and Literature Review.
Familial amyloid polyneuropathy associated with the novel transthyretin variant Arg34Gly.
Familial amyloid polyneuropathy associated with the transthyretin Cys114 gene in a Japanese kindred.
Familial amyloid polyneuropathy associated with transthyretin Gly42 mutation: a quantitative light and electron microscopic study of the peripheral nervous system.
Familial amyloid polyneuropathy in a Spanish family with a transthyretin deletion (deltaVal 122) presenting with carpal tunnel syndrome.
Familial amyloid polyneuropathy in Taiwan: identification of transthyretin variant (Leu55-->Pro).
Familial amyloid polyneuropathy involving a homozygous Val30Met mutation in the amyloidogenic transthyretin gene presenting with superficial siderosis: a case report.
Familial amyloid polyneuropathy related to transthyretin Gly42 in a Japanese family.
Familial amyloid polyneuropathy related to transthyretin mutation Val30 to Leu in a Japanese family.
Familial amyloid polyneuropathy type I (Portuguese): distribution and characterization of renal amyloid deposits.
Familial amyloid polyneuropathy with chronic paroxysmal dry cough in Mainland China: A Chinese family with a proven heterozygous missense mutation c.349G>T in the transthyretin gene.
Familial amyloid polyneuropathy with genetic anticipation associated to a gly47glu transthyretin variant in an Italian kindred.
Familial amyloid polyneuropathy.
Familial Amyloid Polyneuropathy.
Familial amyloid polyneuropathy: a clinico-pathologic study.
Familial amyloid polyneuropathy: alanine-for-threonine substitution in the transthyretin (prealbumin) molecule.
Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways.
Familial amyloid polyneuropathy: When does it stop to be asymptomatic and need a treatment?
Familial amyloidotic polyneuropathy: current and emerging treatment options for transthyretin-mediated amyloidosis.
Familial ATTR amyloidosis: microalbuminuria as a predictor of symptomatic disease and clinical nephropathy.
FAP neuropathy and emerging treatments.
First European consensus for diagnosis, management, and treatment of transthyretin familial amyloid polyneuropathy.
Follow-up in transthyretin familial amyloid polyneuropathy: Useful investigations.
Formulation of Sustained Release Hydrophilic Matrix Tablets of Tolcapone with the Application of Sedem Diagram: Influence of Tolcapone's Particle Size on Sustained Release.
FRET studies of various conformational states adopted by transthyretin.
Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis.
Genotype-phenotype correlation and course of transthyretin familial amyloid polyneuropathies in France.
Genotypic and phenotypic presentation of transthyretin-related familial amyloid polyneuropathy (TTR-FAP) in Turkey.
Haplotypes and DNA sequence variation within and surrounding the transthyretin gene: genotype-phenotype correlations in familial amyloid polyneuropathy (V30M) in Portugal and Sweden.
Health-Related Quality of Life In Patients With Transthyretin Familial Amyloid Polyneuropathy.
Hepatocyte-like cells reveal novel role of SERPINA1 in transthyretin amyloidosis.
Heterogeneity of penetrance in familial amyloid polyneuropathy, ATTR Val30Met, in the Swedish population.
High hydrostatic pressure dissociates early aggregates of TTR105-115, but not the mature amyloid fibrils.
Hsf-1 affects podocyte markers NPHS1, NPHS2 and WT1 in a transgenic mouse model of TTRVal30Met-related amyloidosis.
Immunostaining images of vitreous transthyretin amyloid.
Impact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathy.
In vivo detection of nerve injury in familial amyloid polyneuropathy by magnetic resonance neurography.
Ineffectiveness of dialysis in transthyretin (TTR) clearance in familial amyloid polyneuropathy type I, in spite of lower stability of the TTR Met30 variant.
Inflammatory profiling of patients with familial amyloid polyneuropathy.
Inflammatory state exists in familial amyloid polyneuropathy that may be triggered by mutated transthyretin.
Inhibiting transthyretin amyloid fibril formation via protein stabilization.
Inhibition of human transthyretin aggregation by non-steroidal anti-inflammatory compounds: a structural and thermodynamic analysis.
Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.
Involvement of Macrophages in the Pathogenesis of Familial Amyloid Polyneuropathy and Efficacy of Human iPS Cell-Derived Macrophages in Its Treatment.
Kidney and anemia in familial amyloidosis type I.
Large normal alleles of ATXN2 decrease age at onset in transthyretin familial amyloid polyneuropathy Val30Met patients.
Late-onset and fast progressive neuropathy and cardiomyopathy in Val32Ala transthyretin gene mutation.
Late-onset familial amyloid polyneuropathy (FAP) Val30Met without family history.
Late-onset familial amyloid polyneuropathy in Japan.
Late-onset familial amyloid polyneuropathy: an autopsy study of two Japanese brothers.
Late-onset Transthyretin (TTR)-familial Amyloid Polyneuropathy (FAP) with a Long Disease Duration from Non-endemic Areas in Japan.
Liver transplantation and anemia in familial amyloidosis ATTR V30M.
Liver transplantation as treatment for neurological disorders.
Liver transplantation in transthyretin familial amyloid polyneuropathy: first report from Argentina.
Liver transplantation in transthyretin-related familial amyloid polyneuropathy.
Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy.
Long-term follow-up of survival of liver transplant recipients with familial amyloid polyneuropathy (Portuguese type).
Long-term quantitative evaluation of liver transplantation in familial amyloid polyneuropathy (Portuguese V30M).
Long-term survival after liver transplantation in patients with familial amyloid polyneuropathy.
Long-term treatment of transthyretin familial amyloid polyneuropathy with tafamidis: a clinical and neurophysiological study.
Lower kinetic limit to protein thermal stability: a proposal regarding protein stability in vivo and its relation with misfolding diseases.
Macular and optic disc edema and retinal vascular leakage in familial amyloid polyneuropathy with a transthyretin Val30Met mutation: a case report.
Management of asymptomatic gene carriers of transthyretin familial amyloid polyneuropathy.
Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity.
Modulating conformational factors in transthyretin amyloid.
Molecular genetics of amyloid neuropathy in Europe.
Motor excitability measurements in early stage familial amyloid polyneuropathy: The influence of tafamidis treatment.
MRI of cardiac involvement in transthyretin familial amyloid polyneuropathy.
Multimodal retinal imaging in a Chinese kindred with familial amyloid polyneuropathy secondary to transthyretin Ile107Met mutation.
Multimodal retinal imaging of familial amyloid polyneuropathy.
Muscular amyloid angiopathy with amyloidgenic transthyretin Ser50Ile and Tyr114Cys.
Myopathic phenotype of familial amyloid polyneuropathy with a rare transthyretin variant: ATTR Ala45Asp.
Natural history and survival in stage 1 Val30Met transthyretin familial amyloid polyneuropathy.
Natural history of transthyretin Val30Met familial amyloid polyneuropathy: analysis of late-onset cases from non-endemic areas.
Nerve Ultrasound Comparison Between Transthyretin Familial Amyloid Polyneuropathy and Chronic Inflammatory Demyelinating Polyneuropathy.
Neurodegeneration in familial amyloid polyneuropathy: from pathology to molecular signaling.
Neurophysiological markers of small fibre neuropathy in TTR-FAP mutation carriers.
Neurophysiological techniques to detect early small-fiber dysfunction in transthyretin amyloid polyneuropathy.
New structural information and update on liver transplantation in transthyretin-associated amyloidosis. Report from the 4th International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders & the 3rd International Workshop on Liver Transplantation in Familial Amyloid Polyneuropathy, Umeå Sweden, June 1999.
Norfolk QOL-DN: validation of a patient reported outcome measure in transthyretin familial amyloid polyneuropathy.
Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization.
Occupational and other risk factors for clinically overt familial amyloid polyneuropathy.
Ocular amyloidosis and secondary glaucoma.
On the origin of the transthyretin Val30Met familial amyloid polyneuropathy.
Ophthalmic manifestations in a Chinese family with familial amyloid polyneuropathy due to a TTR Gly83Arg mutation.
Optimizing the management of transthyretin familial amyloid polyneuropathy in Europe: early diagnosis and effective care.
Origin of sporadic late-onset hereditary ATTR Val30Met amyloidosis in Japan.
Parenteral nutrition improves nutritional status, autonomic symptoms and quality of life in transthyretin amyloid polyneuropathy.
Pathology and functional diagnosis of small-fiber painful neuropathy.
Patient-reported outcomes on familial amyloid polyneuropathy (FAP).
Penetrance estimation of TTR familial amyloid polyneuropathy (type I) in Brazilian families.
Pharmacological treatment for familial amyloid polyneuropathy.
Phenotypic expression of familial amyloid polyneuropathy in Brazil.
Phenotypic heterogeneity in a family with FAP due to a TTR Leu58Arg mutation: a clinicopathologic study.
Polymer-doxycycline conjugates as fibril disrupters: an approach towards the treatment of a rare amyloidotic disease.
Poor Yield of Routine Transthyretin Screening in Patients with Idiopathic Neuropathy.
Portuguese-type amyloidosis (transthyretin amyloidosis, ATTR V30M).
Positive Effectiveness of Tafamidis in Delaying Disease Progression in Transthyretin Familial Amyloid Polyneuropathy up to 2 Years: An Analysis from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Post hoc analysis of nutritional status in patients with transthyretin familial amyloid polyneuropathy: impact of tafamidis.
Postmortem findings in a familial amyloid polyneuropathy patient with homozygosity of the mutant Val30Met transthyretin gene.
Potential Role of In Vivo Confocal Microscopy for Imaging Corneal Nerves in Transthyretin Familial Amyloid Polyneuropathy.
Presence of N-glycosylated transthyretin in plasma of V30M carriers in familial amyloidotic polyneuropathy: an escape from ERAD.
Prevalence of Transthyretin Familial Amyloid Polyneuropathy In Portugal.
Progression of myocardial sympathetic denervation assessed by (123)I-MIBG imaging in familial amyloid polyneuropathy and the effect of liver transplantation.
Progression of transthyretin (TTR) amyloidosis in donors and recipients after domino liver transplantation-a prospective single-center cohort study.
Progressive cardiac amyloidosis following liver transplantation for familial amyloid polyneuropathy: implications for amyloid fibrillogenesis.
Progressive wild-type transthyretin deposition after liver transplantation preferentially occurs onto myocardium in FAP patients.
Psychopathological Dimensions in Portuguese Subjects with Transthyretin Familial Amyloid Polyneuropathy.
Quantitative sudomotor test helps differentiate transthyretin familial amyloid polyneuropathy from chronic inflammatory demyelinating polyneuropathy.
Rapid detection of wild-type and mutated transthyretins.
Rational design of potent human transthyretin amyloid disease inhibitors.
Reader response: Natural history and survival in stage 1 Val30Met transthyretin familial amyloid polyneuropathy.
Recent advances in familial amyloid polyneuropathy.
Recommendations for presymptomatic genetic testing and management of individuals at risk for hereditary transthyretin amyloidosis.
Recurrent syncope as persistently isolated feature of transthyretin amyloidotic polyneuropathy.
Reduced myocardial 123-iodine metaiodobenzylguanidine uptake: a prognostic marker in familial amyloid polyneuropathy.
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.
Results of liver transplantation for familial amyloid polyneuropathy type I in Brazil.
Retrospective Mapping of SAR Data for TTR Protein in Chemico-Biological Space Using Ligand Efficiency Indices as a Guide to Drug Discovery Strategies.
Risk of transmission of systemic transthyretin amyloidosis after domino liver transplantation.
S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.
Schwann cell and endothelial cell damage in transthyretin familial amyloid polyneuropathy.
Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Sensory nerve degeneration in a mouse model mimicking early manifestations of familial amyloid polyneuropathy due to transthyretin Ala97Ser.
Sequential (domino) transplantation of the liver in a transthyretin-50 familial amyloid polyneuropathy. Special reference to cardiological diagnosis and complications.
Serum amyloid P component scintigraphy in familial amyloid polyneuropathy: regression of visceral amyloid following liver transplantation.
Serum transthyretin monomer in patients with familial amyloid polyneuropathy.
Severe amyloid deposition in mammary glands of familial amyloid polyneuropathy patients.
Severe heart disease in an unusual case of familial amyloid polyneuropathy type I.
Single-centre experience on transthyretin familial amyloid polyneuropathy: case series and literature review.
Sixty years of transthyretin familial amyloid polyneuropathy (TTR-FAP) in Europe: where are we now? A European network approach to defining the epidemiology and management patterns for TTR-FAP.
Skin Nerve Pathology: Biomarkers of Premanifest and Manifest Amyloid Neuropathy.
Somatostatin analogues for refractory diarrhoea in familial amyloid polyneuropathy.
Spinal cord stimulation markedly ameliorated refractory neuropathic pain in transthyretin Val30Met familial amyloid polyneuropathy.
Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione.
Sudomotor innervation in transthyretin amyloid neuropathy: Pathology and functional correlates.
Support for the multigenic hypothesis of amyloidosis: the binding stoichiometry of retinol-binding protein, vitamin A, and thyroid hormone influences transthyretin amyloidogenicity in vitro.
Sural nerve injury in familial amyloid polyneuropathy: MR neurography vs clinicopathologic tools.
Susceptibility and modifier genes in Portuguese transthyretin V30M amyloid polyneuropathy: complexity in a single-gene disease.
Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
Tafamidis delays disease progression in patients with early stage transthyretin familial amyloid polyneuropathy: additional supportive analyses from the pivotal trial.
Tafamidis delays neurological progression comparably across Val30Met and non-Val30Met genotypes in transthyretin familial amyloid polyneuropathy.
Tafamidis for transthyretin amyloidosis.
Tafamidis for transthyretin familial amyloid polyneuropathy: A randomized, controlled trial.
Tafamidis for transthyretin familial amyloid polyneuropathy: a randomized, controlled trial.
Tafamidis, a Noninvasive Therapy for Delaying Transthyretin Familial Amyloid Polyneuropathy: Systematic Review and Meta-Analysis.
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
Tafamidis: a review of its use in familial amyloid polyneuropathy.
The course and prognostic factors of familial amyloid polyneuropathy after liver transplantation.
The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site.
The diagnostic accuracy of Sudoscan in transthyretin familial amyloid polyneuropathy.
The diagnostic utility of neurophysiologic tests for early diagnostic of transthyretin familial amyloid polyneuropathy.
The effect of tafamidis on the QTC interval in healthy subjects.
The Endoplasmic Reticulum-associated Degradation of Transthyretin Variants Is Negatively Regulated by BiP in Mammalian Cells.
The first Transthyretin Familial Amyloid Polyneuropathy gait quantification study - preliminary results.
The identification of a transthyretin variant p.D38G in a Chinese family with early-onset leptomeningeal amyloidosis.
The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.
The pathological and biochemical identification of possible seed-lesions of transmitted transthyretin amyloidosis after domino liver transplantation.
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies.
The significance of carpal tunnel syndrome in transthyretin Val30Met familial amyloid polyneuropathy.
The Temporal Profiles of Changes in Nerve Excitability Indices in Familial Amyloid Polyneuropathy.
The value of electrochemical skin conductance measurement using Sudoscan® in the assessment of patients with familial amyloid polyneuropathy.
Therapeutic Oligonucleotides Targeting Liver Disease: TTR Amyloidosis.
Three Turkish families with different transthyretin mutations.
Tongue atrophy and fasciculations in transthyretin familial amyloid neuropathy: An ALS mimicker.
Toward the discovery of functional transthyretin amyloid inhibitors: application of virtual screening methods.
Transthyretin Ala97Ser in Chinese-Taiwanese patients with familial amyloid polyneuropathy: genetic studies and phenotype expression.
Transthyretin amyloid polyneuropathies mimicking a demyelinating polyneuropathy.
Transthyretin chemical chaperoning by flavonoids: Structure-activity insights towards the design of potent amyloidosis inhibitors.
Transthyretin enhances nerve regeneration.
Transthyretin familial amyloid polyneuropathy (TTR-FAP) in Mallorca: A comparison between late- and early-onset disease.
Transthyretin familial amyloid polyneuropathy (TTR-FAP): Parameters for early diagnosis.
Transthyretin familial amyloid polyneuropathy due to lle107Val mutation mimicking atypical chronic inflammatory demyelinating polyneuropathy: case report.
Transthyretin Familial Amyloid Polyneuropathy Impact on Health-Related Quality of Life.
Transthyretin familial amyloid polyneuropathy.
Transthyretin familial amyloid polyneuropathy: an update.
Transthyretin gene analysis in European patients with suspected familial amyloid polyneuropathy.
Transthyretin gene mutations in British and French patients with amyloid neuropathy.
Transthyretin Ile84Thr is associated with familial amyloid polyneuropathy.
Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy.
Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity.
Transthyretin is up-regulated by sex hormones in mice liver.
Transthyretin mutation (serine 84) associated with familial amyloid polyneuropathy in a Hungarian family.
Transthyretin mutation (TTRGly47Ala) associated with familial amyloid polyneuropathy in a French family.
Transthyretin mutation Leu-55-Pro significantly alters tetramer stability and increases amyloidogenicity.
Transthyretin related familial amyloid polyneuropathy.
Transthyretin Tyr77 familial amyloid polyneuropathy: a clinicopathological study of a large kindred.
Transthyretin Val 107 in a Japanese patient with familial amyloid polyneuropathy.
Transthyretin Val30Met familial amyloid polyneuropathy: a considerably different clinical picture and natural course in endemic and non-endemic areas.
Transthyretin-Related Familial Amyloid Polyneuropathy (TTR-FAP): A Single-Center Experience in Sicily, an Italian Endemic Area.
Treatment of amyloidosis.
Treatment of transthyretin familial amyloid polyneuropathy with tafamidis: a case report.
Trigger finger as an initial manifestation of familial amyloid polyneuropathy in a patient with Ile107Val TTR.
TTR familial amyloid polyneuropathy: does a mitochondrial polymorphism entirely explain the parent-of-origin difference in penetrance?
TTR kinetic stabilizers and TTR gene silencing: a new era in therapy for familial amyloidotic polyneuropathies.
TTR-familial amyloid polyneuropathy--neurological aspects.
TTR-FAP Progression Evaluation Based on Gait Analysis Using a Single RGB-D Camera.
TTR-related amyloid neuropathy: clinical, electrophysiological and pathological findings in 15 unrelated patients.
Twenty Years of a Pre-Symptomatic Testing Protocol for Late-Onset Neurological Diseases in Portugal.
Two cases of late onset familial amyloid polyneuropathy with a Glu61Lys transthyretin variant.
Type I familial amyloid polyneuropathy. A pathological study of the peripheral nervous system.
Ultrasound evaluation in transthyretin-related amyloid neuropathy.
Unwanted road to anaemia in transthyretin familial amyloid polyneuropathy may continue irrespective of tafamidis treatment.
Up-regulation of the extracellular matrix remodeling genes, biglycan, neutrophil gelatinase-associated lipocalin, and matrix metalloproteinase-9 in familial amyloid polyneuropathy.
Update in the diagnosis and management of transthyretin familial amyloid polyneuropathy.
Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy.
Usefulness of combined nerve and muscle biopsy in the diagnosis of amyloid neuropathy--a study of 6 new cases.
Usefulness of MALDI/TOF mass spectrometry of immunoprecipitated serum variant transthyretin in the diagnosis of familial amyloid polyneuropathy.
Validation of a Single RGB-D Camera for Gait Assessment of Polyneuropathy Patients.
Variants in RBP4 and AR genes modulate age at onset in familial amyloid polyneuropathy (FAP ATTRV30M).
Vitreous amyloidosis after liver transplantation in patients with familial amyloid polyneuropathy: ocular synthesis of mutant transthyretin.
Vitreous Amyloidosis: Ocular, Systemic, and Genetic Insights.
Widespread Cardiac and Vasomotor Autonomic Dysfunction in Non-Val30Met Hereditary Transthyretin Amyloidosis.
Wild-type transthyretin significantly contributes to the formation of amyloid fibrils in familial amyloid polyneuropathy patients with amyloidogenic transthyretin Val30Met.
[Aged onset of amyloidosis caused by transthyretin gene mutations]
[Case report of transthyretin Val30Met familial amyloid polyneuropathy presenting hydrocephalus].
[Clinical and genetic heterogeneity in familial amyloidotic polyneuropathy associated with variant transthyretin]
[Demonstration of genetic mutation in most of the amyloid neuropathies with sporadic occurrence]
[Diagnosis of familial amyloid polyneuropathy type I in Argentina]
[Familial amyloid neuropathy associated with the Cys114 mutation of the transthyretin gene in a Russian family]
[Familial amyloid polyneuropathy: liver transplantation as first-line therapy].
[Familial amyloid polyneuropathy].
[Familial amyloidotic polyneuropathies].
[Genetic analysis and a new therapy for a hereditary disease: familial amyloid polyneuropathy]
[Identification of transthyretin posttranslational modifications 1n human blood using mass-spectrometric methods].
[Liver transplantation in familial amyloid polyneuropathy. Case report and review of the literature]
[Ocular involvement in familial amyloid polyneuropathy].
[Perioperative management for liver transplant in a patient with familial amyloid polyneuropathy with heart involvement.]
[Presentations of transthyretin associated familial amyloid polyneuropathy in Argentina].
[Severe hypocupremia and familial amyloid polyneuropathy].
[The ocular involvement in the transthyretin-related familial amyloid polyneuropathy].
[Transthyretin and familial amyloid polyneuropathies]
[Transthyretin familial amyloid polyneuropathy - three Hungarian cases with rare mutations (His88Arg and Phe33Leu)].
[Two elderly cases of transthyretin amyloid polyneuropathy without a family history].
[Variant transthyretin genes associated with familial amyloid polyneuropathy]
[What's new in hereditary neuropathies ?].
Amyloidosis
(99m)Tc-DPD uptake reflects amyloid fibril composition in hereditary transthyretin amyloidosis.
(99m)Tc-HMDP scintigraphy rectifies wrong diagnosis of AL amyloidosis.
18F-Florbetaben: A New Tool for Amyloidosis Staging?
18F-Florbetapir Binds Specifically to Myocardial Light Chain and Transthyretin Amyloid Deposits: Autoradiography Study.
18F-flutemetamol positron emission tomography in cardiac amyloidosis.
1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy.
2021 Advocacy Statements for the Role of 99mTc-Pyrophosphate Scintigraphy in the Diagnosis of Transthyretin Cardiac Amyloidosis: A Report of the Taiwan Society of Cardiology and the Society of Nuclear Medicine of the Republic of China.
6MWT performance correlates with peripheral neuropathy but not with cardiac involvement in patients with hereditary transthyretin amyloidosis (hATTR).
99mTc DPD is the preferential bone tracer for diagnosis of cardiac transthyretin amyloidosis.
99mTc-DPD scintigraphy in immunoglobulin light chain (AL) cardiac amyloidosis.
99mTc-Pyrophosphate Retention in Atelectatic Pulmonary Tissues of a Patient With Transthyretin Cardiac Amyloidosis.
99mTechnetium pyrophosphate scintigraphy with cadmium zinc telluride cameras is a highly sensitive and specific imaging modality to diagnose transthyretin cardiac amyloidosis.
?-Synuclein aggregation in the saliva of familial transthyretin amyloidosis: a potential biomarker.
A case of a senile systemic amyloidosis patient presenting with angina pectoris and dilated cardiomyopathy.
A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation.
A case of cardiac amyloidosis in an elderly Japanese patient with amyloidogenic transthyretin Val122Ile variant.
A case of cardiac amyloidosis incidentally detected by bone scintigraphy.
A case of late onset cardiac amyloidosis with a new transthyretin variant (lysine 92).
A Case of Late-onset Hereditary ATTR Amyloidosis with a Novel p.P63S (P43S) Transthyretin Variant.
A case of transthyretin amyloidosis with myopathy, neuropathy, and cardiomyopathy resulting from an exceedingly rare mutation transthyretin Ala120Ser (c.418G?>?T, p.Ala140Ser).
A case of unilateral shoulder joint hydrarthrosis with wild-type amyloidogenic transthyretin amyloidosis.
A case of vitreous amyloidosis without systemic symptoms in familial amyloidotic polyneuropathy.
A case of wild-type transthyretin amyloidosis associated with organizing pneumonia.
A case of wild-type transthyretin cardiac amyloidosis with rheumatoid arthritis.
A case report of an uncommon presentation of 99mtechnetium pyrophosphate scintigraphy in transthyretin cardiac amyloidosis: A potential diagnostic pitfall, pseudo-positive or pseudo-negative?
A case report of osteoarthritis associated with hereditary transthyretin amyloidosis ATTRV30M.
A case study of likely wild-type cardiac transthyretin amyloidosis causing rapid deterioration.
A cell-based high-throughput screening method to directly examine transthyretin amyloid fibril formation at neutral pH.
A challenging road to diagnosing transthyretin cardiac amyloidosis and using technetium-99m pyrophosphate bone scintigraphy in nuclear cardiology - A case report.
A circulating, disease-specific, mechanism-linked biomarker for ATTR polyneuropathy diagnosis and response to therapy prediction.
A complex equilibrium among partially unfolded conformations in monomeric transthyretin.
A compound T60A and V122I heterozygosity in the transthyretin gene causing early onset severe cardiac amyloidosis.
A comprehensive safety profile of tafamidis in patients with transthyretin amyloid polyneuropathy.
A current pharmacologic agent versus the promise of next generation therapeutics to ameliorate protein misfolding and/or aggregation diseases.
A deceptive case of amyloid myopathy: clinical and magnetic resonance imaging features.
A Descriptive Analysis of ATTR Amyloidosis in Spain from the Transthyretin Amyloidosis Outcomes Survey.
A Focused Review on the Pathophysiology, Diagnosis, and Management of Cardiac Amyloidosis.
A genealogical and clinical study of the phenotypical variation within the Swedish transthyretin His88Arg (p. His108Arg) amyloidosis family.
A Heart too Stiff to Beat: A Case of Familial Transthyretin Amyloidosis Cardiomyopathy.
A homozygous transthyretin variant associated with senile systemic amyloidosis: evidence for a late-onset disease of genetic etiology.
A late-onset case of hereditary transthyretin amyloidosis with a novel compound heterozygous mutation.
A library of ATTR amyloidosis patient-specific induced pluripotent stem cells for disease modelling and in vitro testing of novel therapeutics.
A look into amyloid formation by transthyretin: aggregation pathway and a novel kinetic model.
A machine learning model for identifying patients at risk for wild-type transthyretin amyloid cardiomyopathy.
A molecular correlate of clinicopathology in transthyretin amyloidosis.
A molecular mechanism for transthyretin amyloidogenesis.
A mouse model of a novel missense mutation (Gly83Arg) in a Chinese kindred manifesting vitreous amyloidosis only.
A multi-modal diagnostic model improves detection of cardiac amyloidosis among patients with diagnostic confirmation by cardiac biopsy.
A Mutation in NPAS3 That Segregates with Schizophrenia in a Small Family Leads to Protein Aggregation.
A Narrative Review of the Role of Transthyretin in Health and Disease.
A new amyloidogenic transthyretin variant (Val122Ala) found in a compound heterozygous patient.
A new amyloidogenic transthyretin variant, [D38A], detected by electrospray ionization/mass spectrometry.
A New Arg54Gly Transthyretin Gene Mutation Associated with Vitreous Amyloidosis in Chinese.
A new crystal form of human transthyretin obtained with a curcumin derived ligand.
A new diagnostic procedure to detect unknown transthyretin (TTR) mutations in familial amyloidotic polyneuropathy (FAP).
A new human hereditary amyloidosis: the result of a stop-codon mutation in the apolipoprotein AII gene.
A new isoleucine substitution of Val-20 in transthyretin tetramers selectively impairs dimer-dimer contacts and causes systemic amyloidosis.
A new prion disease: relationship with central and peripheral amyloidoses.
A new simple and rapid screening method for variant transthyretin-related amyloidosis.
A new staging system for cardiac transthyretin amyloidosis.
A new therapy for transthyretin amyloidosis, no longer an orphan condition.
A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis.
A new transthyretin mutation associated with amyloidotic vitreous opacities. Asparagine for isoleucine at position 84.
A new transthyretin mutation associated with leptomeningeal amyloidosis.
A new transthyretin variant Leu55Gln in a patient with systemic amyloidosis.
A novel amyloidogenic transthyretin variant, Gly53Ala, associated with intermittent headaches and ataxia.
A novel bis-furan scaffold for transthyretin stabilization and amyloid inhibition.
A novel risk score to predict survival in advanced heart failure due to cardiac amyloidosis.
A novel tool for detecting amyloid deposits in systemic amyloidosis in vitro and in vivo.
A novel transthyretin Lys70Glu (p.Lys90Glu) mutation presenting with vitreous amyloidosis and carpal tunnel syndrome.
A novel transthyretin variant p.H110D (H90D) as a cause of familial amyloid polyneuropathy in a large Irish kindred.
A novel type of familial transthyretin amyloidosis, ATTR Asn124Ser, with co-localization of kappa light chains.
A novel variant of transthyretin (Glu42Asp) associated with sporadic late-onset cardiac amyloidosis.
A novel variant of transthyretin, 59Thr-->Lys, associated with autosomal dominant cardiac amyloidosis in an Italian family.
A pair of peptides inhibits seeding of the hormone transporter transthyretin into amyloid fibrils.
A Patient With Hereditary ATTR and a Novel AGel p.Ala578Pro Amyloidosis.
A phase II, open-label, extension study of long-term patisiran treatment in patients with hereditary transthyretin-mediated (hATTR) amyloidosis.
A practical approach to the diagnosis of systemic amyloidoses.
A Proteomic Atlas of Cardiac Amyloid Plaques.
A rare transthyretin mutation (Asp18Glu) associated with cardiomyopathy.
A rare variant of transthyretin-related amyloidosis associated with exclusive cardiomyopathy in a Hong Kong Chinese patient.
A representative case of hereditary transthyretin amyloidosis complicated by intramyocardial hemorrhage.
A Review of Novel Agents and Clinical Considerations in Patients With ATTR Cardiac Amyloidosis.
A Review of Patisiran (ONPATTRO®) for the Treatment of Polyneuropathy in People with Hereditary Transthyretin Amyloidosis.
A Review of Tafamidis for the Treatment of Transthyretin-Related Amyloidosis.
A review of the amyloidoses that infiltrate the heart.
A serine protease secreted from Bacillus subtilis cleaves human plasma transthyretin to generate an amyloidogenic fragment.
A simple and reliable method of detecting variant transthyretins by multidimensional liquid chromatography coupled to electrospray ionization mass spectrometry.
A simple core dataset and disease severity score for hereditary transthyretin (ATTRv) amyloidosis.
A simple screening test for variant transthyretins associated with familial transthyretin amyloidosis using isoelectric focusing.
A specific test for transthyretin 122 (Val----Ile), based on PCR-primer-introduced restriction analysis (PCR-PIRA): confirmation of the gene frequency in blacks.
A sporadic case of late-onset familial amyloid polyneuropathy with a monoclonal gammopathy.
A Statement on the Appropriate Administration of Tafamidis in Patients With Transthyretin Cardiac Amyloidosis.
A study of the neuropathy associated with transthyretin amyloidosis (ATTR) in the UK.
A transthyretin mutation (Tyr78Phe) associated with peripheral neuropathy, carpal tunnel syndrome and skin amyloidosis.
Abdominal fat pad biopsies exhibit good diagnostic accuracy in patients with suspected transthyretin amyloidosis.
Abdominal fat pad excisional biopsy for the diagnosis and typing of systemic amyloidosis.
Abnormal Coronary Flow Velocity Reserve and Decreased Myocardial Contractile Reserve Are Main Factors in Relation to Physical Exercise Capacity in Cardiac Amyloidosis.
Abnormal small bowel motility in patients with hereditary transthyretin amyloidosis.
Accuracy of 99mTc-Hydroxymethylene diphosphonate scintigraphy for diagnosis of transthyretin cardiac amyloidosis.
Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC.
Acidic pH-induced conformational changes in amyloidogenic mutant transthyretin.
Acquired and inherited amyloidosis: Knowledge driving patients' care.
Acquired transthyretin amyloidosis after domino liver transplant: Phenotypic correlation, implication of liver retransplantation.
Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis.
Acute cardiac failure secondary to senile systemic amyloidosis.
Addressing Common Questions Encountered in the Diagnosis and Management of Cardiac Amyloidosis.
Advances in Diagnosis and Treatment of Cardiac and Renal Amyloidosis.
Advances in PET-Based Cardiac Amyloid Radiotracers.
Advances in the diagnosis and treatment of transthyretin amyloidosis with cardiac involvement.
Advances in the Treatment of Cardiac Amyloidosis.
Advances in the treatment of hereditary transthyretin amyloidosis: A review.
Advances in Treatment of ATTRv Amyloidosis: State of the Art and Future Prospects.
Advances in Treatment of Cardiac Amyloid.
Advantages and Emerging Problems of Novel Treatments for Transthyretin Cardiac Amyloidosis.
Affinity capillary electrophoresis is a powerful tool to identify transthyretin binding drugs for potential therapeutic use in amyloidosis.
AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin.
Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis.
Age-related amyloidosis outside the brain: A state-of-the-art review.
Age-related oxidative modifications of transthyretin modulate its amyloidogenicity.
Aged vervet monkeys developing transthyretin amyloidosis with the human disease-causing Ile122 allele: a valid pathological model of the human disease.
Ageing and amyloid fibrillogenesis: lessons from apolipoprotein AI, transthyretin and islet amyloid polypeptide.
Aging and transthyretin-related amyloidosis: pathologic examinations in pulmonary amyloidosis.
Ahmed valve for secondary glaucoma in patients with hereditary transthyretin amyloidosis.
Albumin/creatinine (uACR) and protein/creatinine (uPCR) ratios in spot urine samples can be used to evaluate albuminuria and proteinuria in hereditary transthyretin amyloidosis patients.
Allele specific expression of the transthyretin gene in swedish patients with hereditary transthyretin amyloidosis (ATTR V30M) is similar between the two alleles.
Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: a possible model for senile systemic amyloidosis.
Amyloid and peripheral nervous system disease.
Amyloid cardiomyopathy in a large integrated health care system.
Amyloid Cardiomyopathy in Hereditary Transthyretin V30M Amyloidosis - Impact of Sex and Amyloid Fibril Composition.
Amyloid cardiomyopathy.
Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology.
Amyloid diseases of the heart: current and future therapies.
Amyloid fibril composition and transthyretin gene structure in senile systemic amyloidosis.
Amyloid Fibril Composition as a Predictor of Development of Cardiomyopathy After Liver Transplantation for Hereditary Transthyretin Amyloidosis.
Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis.
Amyloid fibril composition within hereditary Val30Met (p. Val50Met) transthyretin amyloidosis families.
Amyloid fibril protein in familial amyloidosis with cranial neuropathy and corneal lattice dystrophy (FAP type IV) is related to transthyretin.
Amyloid localized to tenosynovium at carpal tunnel release. Immunohistochemical identification of amyloid type.
Amyloid PET imaging in cardiac amyloidosis: a pilot study using 18F-flutemetamol positron emission tomography.
Amyloid Polyneuropathy and Myocardial Amyloidosis 10 Years after Domino Liver Transplantation from a Patient with a Transthyretin Ser50Arg Mutation.
Amyloid Polyneuropathy Caused By Wild-Type Transthyretin.
Amyloid polyneuropathy with transthyretin Arg50 in a Japanese case from Osaka.
Amyloid proteins and amyloidoses: complexity updated.
Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition.
Amyloid transthyretin cardiac amyloidosis: diagnosis and management.
Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue.
Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage.
Amyloidosis and cardiovascular diseases: A clinical insight.
Amyloidosis and Ocular Involvement: an Overview.
Amyloidosis and Unexpected Death: A Review of Seven Cases.
Amyloidosis as a Systemic Disease in Context.
Amyloidosis cardiomyopathy: update in the diagnosis and treatment of the most common types.
Amyloidosis Diagnosed in Solid Organ Transplant Recipients.
Amyloidosis in Heart Failure.
Amyloidosis of the gastrointestinal tract: a 13-year single center referral experience.
Amyloidosis with Cardiac Involvement: Identification, Characterization, and Management.
Amyloidosis: diagnosis and new therapies for a misunderstood and misdiagnosed disease.
Amyloidosis: Multisystem Spectrum of Disease with Pathologic Correlation.
Amyloidotic breast nodule in hereditary transthyretin amyloidosis (hATTR): a case report.
An aggressive form of transthyretin amyloidosis.
An autopsy case of leptomeningeal amyloidosis associated with transthyretin Gly47Arg mutation.
An Exploratory Study of Cognitive Involvement in Hereditary Transthyretin Amyloidosis.
An optimized imaging protocol for [99mTc]Tc-DPD scintigraphy and SPECT/CT quantification in cardiac transthyretin (ATTR) amyloidosis.
An unusual case of hereditary transthyretin-related amyloidosis and ulcerative colitis in a young Indian girl.
Analysis of serum transthyretin by on-line immunoaffinity solid-phase extraction capillary electrophoresis mass spectrometry using magnetic beads.
Analysis of the TTR gene in the investigation of amyloidosis: A 25-year single UK center experience.
Analysis of transthyretin in human serum by capillary zone electrophoresis electrospray ionization time-of-flight mass spectrometry. Application to familial amyloidotic polyneuropathy type I.
Angiographic Signatures of the Predominant Form of Familial Transthyretin Amyloidosis (Val30Met Mutation).
Animal models of human amyloidoses: are transgenic mice worth the time and trouble?
Anion shielding of electrostatic repulsions in transthyretin modulates stability and amyloidosis: insight into the chaotrope unfolding dichotomy.
Anterior Chamber Flare as an Objective and Quantitative Noninvasive Method for Oculopathy in Transthyretin V30M Amyloidosis Patients.
Anticipation on age at onset in kindreds with hereditary ATTRV30M amyloidosis from the Majorcan cluster.
Anticoagulation with warfarin compared to novel oral anticoagulants for atrial fibrillation in adults with transthyretin cardiac amyloidosis: comparison of thromboembolic events and major bleeding.
Aortic Stenosis and Cardiac Amyloidosis: JACC Review Topic of the Week.
Aortic stenosis and transthyretin cardiac amyloidosis: the chicken or the egg?
Aortic stenosis, transcatheter aortic valve replacement and transthyretin cardiac amyloidosis: are we progressively unraveling the tangle?
Aortic Valve Calcium in Patients With Transthyretin Cardiac Amyloidosis: A Propensity-Matched Analysis.
Apical sparing pattern of left ventricular myocardial (99m)Tc-HMDP uptake in patients with transthyretin cardiac amyloidosis.
Apical Sparing Pattern of Longitudinal Strain and Positive Bone Scintigraphy in Metastatic Myocardial Calcification.
APOE polymorphism in ATTR amyloidosis patients treated with lipid nanoparticle siRNA.
Apolipoprotein AI and transthyretin as components of amyloid fibrils in a kindred with apoAI Leu178His amyloidosis.
Applications of gene therapy for familial amyloidotic polyneuropathy.
Applying an artificial neural network model for developing a severity score for patients with hereditary amyloid polyneuropathy.
Are cardiomyocytes able to generate pre-amyloid peptides?
Arrhythmia--a pitfall in tests of cardiac autonomic function after liver transplantation for familial amyloidotic polyneuropathy: a long-term follow-up of Swedish patients.
Arrhythmias in Cardiac Amyloidosis.
Asp58Ala is the Predominant Mutation of the TTR Gene in Korean Patients with Hereditary Transthyretin-Related Amyloidosis.
Assessment of patients with hereditary transthyretin amyloidosis - understanding the impact of management and disease progression.
Association between a point mutation at the -743-bp region of the transthyretin (TTR) gene and familial vitreous amyloidosis.
Association between aortic stenosis and hereditary transthyretin amyloidosis.
Association between hearing loss and hereditary ATTR amyloidosis.
Association Between Ruptured Distal Biceps Tendon and Wild-Type Transthyretin Cardiac Amyloidosis.
Association of Carpal Tunnel Syndrome With Amyloidosis, Heart Failure, and Adverse Cardiovascular Outcomes.
Association of Low Plasma Transthyretin Concentration With Risk of Heart Failure in the General Population.
Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis: The APOLLO Study.
Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry.
Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry.
Association of the V122I Transthyretin Amyloidosis Genetic Variant With Cardiac Structure and Function in Middle-aged Black Adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study.
Atrial fibrillation ablation in patients with transthyretin cardiac amyloidosis.
Atrial Fibrillation and Central Nervous Complications in Liver Transplanted Hereditary Transthyretin Amyloidosis Patients.
Atrial fibrillation and subtype of atrial fibrillation in cardiac amyloidosis: clinical and echocardiographic features, impact on mortality.
Atrial Fibrillation in Transthyretin Cardiac Amyloidosis: Predictors, Prevalence, and Efficacy of Rhythm Control Strategies.
Atrial Fibrillation in Transthyretin Cardiac Amyloidosis: The Growing Need to Look Forward.
Atrial impairment in transthyretin cardiac amyloidosis: an early marker of cardiac involvement and a prognostic factor.
ATTR amyloidosis during the COVID-19 pandemic: insights from a global medical roundtable.
ATTRv in Lazio-Italy: A High-Prevalence Region in a Non-Endemic Country.
Atypical presentation of transthyretin amyloidosis in a non-endemic area.
Autonomic involvement in hereditary transthyretin amyloidosis (hATTR amyloidosis).
Autonomic neuropathies.
Autopsy evaluation of the implantation site of a His bundle pacing lead demonstrating selective capture.
Autosomal-dominant transthyretin (TTR)-related amyloidosis is not a frequent CMT2 neuropathy "in disguise".
Avoiding misdiagnosis: expert consensus recommendations for the suspicion and diagnosis of transthyretin amyloidosis for the general practitioner.
Baseline disease characteristics in Brazilian patients enrolled in Transthyretin Amyloidosis Outcome Survey (THAOS).
Baseline ECG Features and Arrhythmic Profile in Transthyretin Versus Light Chain Cardiac Amyloidosis.
Becoming familiar with hereditary transthyretin amyloidosis, a treatable neuropathy.
Beneficial Effect of Pimobendan for Severe Heart Failure Due to Transthyretin Cardiac Amyloidosis.
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.
Best Practices in Specialized Amyloidosis Centers in the United States: A Survey of Cardiologists, Nurses, Patients, and Patient Advocates.
Beyond Val30Met transthyretin (TTR): variants associated with age-at-onset in hereditary ATTRv amyloidosis.
Bifunctional crosslinking ligands for transthyretin.
Binding and stabilization of transthyretin by curcumin.
Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short- and Long-Distance Conformational Changes.
Binding site asymmetry in human transthyretin: insights from a joint neutron and X-ray crystallographic analysis using perdeuterated protein.
Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes.
Biochemical characteristics of variant transthyretins causing hereditary leptomeningeal amyloidosis.
Biochemical characterization of vitreous and cardiac amyloid in Ile84Ser transthyretin amyloidosis.
Biophysical analysis of normal transthyretin: implications for fibril formation in senile systemic amyloidosis.
Biopsy Evidence of Sequential Transthyretin and Immunoglobulin Light-Chain Cardiac Amyloidosis in the Same Patient.
Blood pressure and orthostatic hypotension as measures of autonomic dysfunction in patients from the transthyretin amyloidosis outcomes survey (THAOS).
Blood-based microRNA profiling in patients with cardiac amyloidosis.
Bone scintigraphy for early detection of transthyretin cardiac amyloidosis.
Bone Scintigraphy Imaging for Transthyretin Cardiac Amyloidosis: Still Much to Learn.
Burden of hereditary transthyretin amyloidosis on quality of life.
Can echocardiography and ECG discriminate hereditary transthyretin V30M amyloidosis from hypertrophic cardiomyopathy?
Can Nuclear Imaging Techniques Predict Patient Outcome and Guide Medical Management in Hereditary Transthyretin Cardiac Amyloidosis?
Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis.
Canadian Guidelines for Hereditary Transthyretin Amyloidosis Polyneuropathy Management.
Cardiac AA amyloidosis in a patient with obstructive hypertrophic cardiomyopathy.
Cardiac amyloidosis associated with a novel transthyretin aspartic acid-18 glutamic acid de novo mutation.
Cardiac Amyloidosis Associated With Amyloidogenic Transthyretin V122I Variant in an Elderly Japanese Woman.
Cardiac amyloidosis associated with the transthyretin Ile122 mutation in a Caucasian family.
Cardiac Amyloidosis Detected on Imaging of Patients with Heart Failure.
Cardiac amyloidosis detection by early bisphosphonate (99mTc-HMDP) scintigraphy.
Cardiac Amyloidosis for the Primary Care Provider: A Practical Review to Promote Earlier Recognition of Disease.
Cardiac amyloidosis imaging with amyloid positron emission tomography: A systematic review and meta-analysis.
Cardiac amyloidosis in African Americans: comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis.
Cardiac amyloidosis in non-transplant cardiac surgery.
Cardiac amyloidosis is associated with increased aortic stiffness.
Cardiac Amyloidosis Phenotype Associated With a Glu89Lys Transthyretin Mutation.
Cardiac Amyloidosis Presenting as Biventricular Systolic Heart Failure.
Cardiac amyloidosis, a monoclonal gammopathy and a potentially misleading mutation.
Cardiac amyloidosis-A review of current literature for the practicing physician.
Cardiac Amyloidosis-Challenging Diagnosis and Unclear Clinical Picture.
Cardiac amyloidosis.
Cardiac amyloidosis: a review and report of a new transthyretin (prealbumin) variant.
Cardiac amyloidosis: An underdiagnosed/underappreciated disease.
Cardiac amyloidosis: An update on diagnosis and treatment.
Cardiac amyloidosis: An update on pathophysiology, diagnosis, and treatment.
Cardiac Amyloidosis: Diagnosis and Treatment Strategies.
Cardiac amyloidosis: diagnostic challenges and recent advancement in the treatment of transthyretin amyloidosis (ATTR).
Cardiac amyloidosis: do not forget to look for it.
Cardiac amyloidosis: evolving approach to diagnosis and management.
Cardiac amyloidosis: heterogenous pathogenic backgrounds.
Cardiac amyloidosis: in search of the ideal diagnostic tool.
Cardiac Amyloidosis: Multimodal Imaging of Disease Activity and Response to Treatment.
Cardiac Amyloidosis: Overlooked, Underappreciated, and Treatable.
Cardiac Amyloidosis: Presentations, Diagnostic Work-up and Collaborative Approach for Comprehensive Clinical Management.
Cardiac amyloidosis: report of a patient heterozygous for the transthyretin isoleucine 122 variant.
Cardiac amyloidosis: the need for early diagnosis.
Cardiac amyloidosis: Updates in diagnosis and management.
Cardiac Amyloidosis: Updates in Imaging.
Cardiac amyloidosis: where are we today?
Cardiac and peripheral vasomotor autonomic functions in hereditary transthyretin amyloidosis with non-Val30Met mutation.
Cardiac Care of Patients with Cardiac Amyloidosis.
Cardiac denervation evidenced by MIBG occurs earlier than amyloid deposits detection by diphosphonate scintigraphy in TTR mutation carriers.
Cardiac devices in patients with transthyretin amyloidosis: Impact on functional class, left ventricular function, mitral regurgitation, and mortality.
Cardiac Dysautonomia and Survival in Hereditary Transthyretin Amyloidosis.
Cardiac Dysautonomia Predicts Long-Term Survival in Hereditary Transthyretin Amyloidosis After Liver Transplantation.
Cardiac Findings and Events Observed in an Open-Label Clinical Trial of Tafamidis in Patients with non-Val30Met and non-Val122Ile Hereditary Transthyretin Amyloidosis.
Cardiac involvement after liver transplantation in patients with Val30Met transthyretin amyloidosis from Majorca focus.
Cardiac involvement in a large cohort of patients with Val30Met transthyretin amyloidosis from Majorca focus.
Cardiac Involvement in a Patient Cohort With Val30Met Mutation Transthyretin Amyloidosis.
Cardiac Involvement Secondary to a Familial Form of Transthyretin Amyloidosis Resulting From the Glu54Gln Mutation.
Cardiac involvement, morbidity and mortality in hereditary transthyretin amyloidosis because of p.Glu89Gln mutation.
Cardiac manifestations and prognostic implications of hereditary transthyretin amyloidosis associated with transthyretin Ala97Ser.
Cardiac Resynchronization Therapy for Transthyretin Cardiac Amyloidosis.
Cardiac scintigraphy with 99mTc-diphosphonates in cardiac amyloidosis.
Cardiac Structural and Functional Consequences of Amyloid Deposition by Cardiac Magnetic Resonance and Echocardiography and Their Prognostic Roles.
Cardiac sympathetic denervation in familial amyloid polyneuropathy assessed by iodine-123 metaiodobenzylguanidine scintigraphy and heart rate variability.
Cardiac sympathetic denervation in wild-type transthyretin amyloidosis.
Cardiac transthyretin amyloidosis 99mTc-DPD SPECT correlates with strain echocardiography and biomarkers.
Cardiac transthyretin amyloidosis.
Cardiac Transthyretin Amyloidosis: A Nuclear Medicine Leading Role. Situation in a Spanish Center and "State of the Art" in Nuclear Medicine.
Cardiomyopathy in a Japanese family with the Glu61Lys transthyretin variant: a new phenotype.
Cardiovascular autonomic functions in late-onset hereditary transthyretin amyloidosis with Val30Met mutation.
Carpal tunnel syndrome and associated symptoms as first manifestation of hATTR amyloidosis.
Carpal tunnel syndrome and spinal canal stenosis: harbingers of transthyretin amyloid cardiomyopathy?
Carpal Tunnel Syndrome Due to Iatrogenic Amyloidosis After Domino Liver Transplantation From Hereditary Transthyretin Amyloidosis: A Case Report.
Carpal tunnel syndrome in cardiac amyloidosis: implications for early diagnosis and prognostic role across the spectrum of aetiologies.
Carpal Tunnel Syndrome in Transthyretin Cardiac Amyloidosis: Implications and Protocol for Diagnosis and Treatment.
Carpal tunnel syndrome is associated with high fibrinogen and fibrinogen deposits.
Carpal Tunnel Syndrome: A Potential Early, Red-Flag Sign of Amyloidosis.
Case report of a young patient with transthyretin amyloidosis associated with Gly67Ala mutation.
Cases from a busy nuclear cardiology laboratory: Potential pitfalls in the interpretation of cardiac scintigraphy for ATTR cardiac amyloidosis.
Catheter Ablation for Atrial Arrhythmias in Patients With Cardiac Amyloidosis.
Cause of death analysis and temporal trends in survival after liver transplantation for transthyretin familial amyloid polyneuropathy.
Causes and Consequences of Longitudinal LV Dysfunction Assessed by 2D Strain Echocardiography in Cardiac Amyloidosis.
Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgitation, SGLT2 Inhibitors, ARNI in HFpEF, and Tafamidis in Amyloidosis.
Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.
Cellular secretion and cytotoxicity of transthyretin mutant proteins underlie late-onset amyloidosis and neurodegeneration.
Cerebral embolism secondary to cardiac amyloidosis: A case report and literature review.
Cerebrospinal fluid and vitreous body exposure to orally administered tafamidis in hereditary ATTRV30M (p.TTRV50M) amyloidosis patients.
Cervicomedullary compression as the main manifestation of wild-type transthyretin amyloidosis.
Challenges and Strategies in the Diagnosis of Cardiac Amyloidosis.
Chance or challenge, spoilt for choice? New recommendations on diagnostic and therapeutic considerations in hereditary transthyretin amyloidosis with polyneuropathy: the German/Austrian position and review of the literature.
Change in N-terminal pro-B-type natriuretic peptide at 1 year predicts mortality in wild-type transthyretin amyloid cardiomyopathy.
Changes in nerve excitability indices in hereditary transthyretin amyloidosis.
Changes in the perceived epidemiology of amyloidosis: 20 year-experience from a Tertiary Referral Centre in Tuscany.
Changes in tissue proteome associated with ATTR amyloidosis: insights into pathogenesis.
Characterisation of serum transthyretin by electrospray ionisation-ion mobility mass spectrometry: Application to familial amyloidotic polyneuropathy type I (FAP-I).
Characteristics of acquired transthyretin amyloidosis: A case series and review of the literature.
Characteristics of Patients with Hereditary Transthyretin Amyloidosis and an Evaluation of the Safety of Tafamidis Meglumine in Japan: An Interim Analysis of an All-case Postmarketing Surveillance.
Characteristics of Patients with Late- vs. Early-Onset Val30Met Transthyretin Amyloidosis from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Characteristics of South Korean Patients with Hereditary Transthyretin Amyloidosis.
Characterization of end-stage renal disease after liver transplantation in transthyretin amyloidosis (ATTR V30M).
Characterization of population genetic structure of hereditary transthyretin amyloidosis in Bulgaria.
Characterization of the transthyretin acid denaturation pathways by analytical ultracentrifugation: implications for wild-type, V30M, and L55P amyloid fibril formation.
Characterization of transthyretin mutants from serum using immunoprecipitation, HPLC/electrospray ionization and matrix-assisted laser desorption/ionization mass spectrometry.
Characterization of transthyretin variants in familial transthyretin amyloidosis by mass spectrometric peptide mapping and DNA sequence analysis.
Characterization of untyped cardiac amyloidosis by mass spectrometry in a patient with Gly6Ser transthyretin polymorphism in fatal cardiogenic shock.
Characterizing the High Disease Burden of Transthyretin Amyloidosis for Patients and Caregivers.
Charcot-Marie-Tooth Disease and Other Hereditary Neuropathies.
Chinese familial transthyretin amyloidosis with vitreous involvement is associated with the transthyretin mutation Gly83Arg: a case report and literature review.
Choroidal Neovascularization in Familial Transthyretin Amyloidosis.
Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.
Chromolaena odorata (Siam weed): A natural reservoir of bioactive compounds with potent anti-fibrillogenic, antioxidative, and cytocompatible properties.
Circulating matrix metalloproteinases and tissue inhibitors of metalloproteinases in cardiac amyloidosis.
Circulating microRNAs Profile in Patients With Transthyretin Variant Amyloidosis.
Clearance of extracellular misfolded proteins in systemic amyloidosis: Experience with transthyretin.
Clinical 3-D Gait Assessment of Patients With Polyneuropathy Associated With Hereditary Transthyretin Amyloidosis.
Clinical and echocardiographic characteristics for differentiating between transthyretin-related and light-chain cardiac amyloidoses.
Clinical and genetic profiles of hereditary transthyretin amyloidosis in Taiwan.
Clinical and pathological findings in familial amyloid polyneuropathy caused by a transthyretin E61K mutation.
Clinical and pathological studies of cardiac amyloidosis in transthyretin type familial amyloid polyneuropathy.
Clinical approach to genetic testing in amyloid cardiomyopathy: from mechanism to effective therapies.
Clinical characteristics and prognosis of cardiac amyloidosis defined by mass spectrometry-based proteomics in an Australian cohort.
Clinical characteristics in patients with hereditary amyloidosis with Glu54Gln transthyretin identified in the Romanian population.
Clinical characteristics of wild-type transthyretin cardiac amyloidosis: disproving myths.
Clinical comparison of V122I genotypic variant of transthyretin amyloid cardiomyopathy with wild-type and other hereditary variants: a systematic review.
Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy.
Clinical diagnosis and typing of systemic amyloidosis in subcutaneous fat aspirates by mass spectrometry-based proteomics.
Clinical Experience With the Use of Doxycycline and Ursodeoxycholic Acid for the Treatment of Transthyretin Cardiac Amyloidosis.
Clinical features and survival in senile systemic amyloidosis: comparison to familial transthyretin cardiomyopathy.
Clinical Images: Carpal tunnel biopsy identifying transthyretin amyloidosis.
Clinical improvement and amyloid regression after liver transplantation in hereditary transthyretin amyloidosis.
Clinical Phenotyping of Transthyretin Cardiac Amyloidosis with Bone-Seeking Radiotracers in Heart Failure with Preserved Ejection Fraction.
Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology.
Clinical Presentation, Diagnosis and Treatment of TTR Amyloidosis.
Clinical symptomatic de novo systemic transthyretin amyloidosis 9 years after domino liver transplantation.
Clinical, ECG and echocardiographic clues to the diagnosis of TTR-related cardiomyopathy.
Clinicopathological and biochemical findings of late-onset hereditary transthyretin amyloidosis 16 years after liver transplantation: an autopsy case study.
Clinicopathological and biochemical findings of thyroid amyloid in hereditary transthyretin amyloidosis with and without liver transplantation.
Clinicopathological correlations of sural nerve biopsies in TTR Val30Met familial amyloid polyneuropathy.
Clinicopathological features of clinically undiagnosed sporadic transthyretin cardiac amyloidosis: a forensic autopsy-based series.
Clinicopathological features of senile systemic amyloidosis: an ante- and post-mortem study.
Clusterin regulates transthyretin amyloidosis.
CNS involvement in V30M transthyretin amyloidosis: clinical, neuropathological and biochemical findings.
Codeposition of apolipoprotein A-IV and transthyretin in senile systemic (ATTR) amyloidosis.
Coexistence of aortic valve stenosis and cardiac amyloidosis: echocardiographic and clinical significance.
Coexistence of familial transthyretin amyloidosis ATTR Val30Met and spinocerebellar ataxia type 1 in a Japanese family--a follow-up autopsy report.
Coexistence of transthyretin- and A?-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis.
Coexistent asymptomatic myeloma and hereditary cardiac amyloidosis: an unusual case of heart failure.
Combination of Commonly Examined Parameters Is a Useful Predictor of Positive 99 mTc-Labeled Pyrophosphate Scintigraphy Findings in Elderly Patients With Suspected Transthyretin Cardiac Amyloidosis.
Combined heart and liver transplantation for familial amyloidotic neuropathy.
Combining ECG and echocardiography to identify transthyretin cardiac amyloidosis in heart failure.
Comments on pupillometry: An objective test to assess endocular hereditary transthyretin amyloidosis.
Common clinicopathological features in late-onset hereditary transthyretin amyloidosis (Ala97Gly, Val94Gly and Val30Met).
Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin.
Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils.
Comparison of 18F-sodium fluoride positron emission tomography imaging and 99mTc-pyrophosphate in cardiac amyloidosis.
Comparison of capillary electrophoresis and capillary liquid chromatography coupled to mass spectrometry for the analysis of transthyretin in human serum.
Comparison of cardiac amyloidosis due to wild-type and V122I transthyretin in older adults referred to an academic medical center.
Comparison of different types of cardiac amyloidosis by cardiac magnetic resonance imaging.
Comparison of planar with tomographic pyrophosphate scintigraphy for transthyretin cardiac amyloidosis: Perils and pitfalls.
Comparison of quantitative sensory testing and heart rate variability in Swedish Val30Met ATTR.
Comparison of the standard and speckle tracking echocardiographic features of wild-type and mutated transthyretin cardiac amyloidoses.
Comparison of the United Kingdom and United States approaches to approval of new neuromuscular therapies.
Computational studies on transthyretin.
Confirming the Diagnosis of Amyloidosis.
Conjunctival lymphangiectasia as a biomarker of severe systemic disease in Ser77Tyr hereditary transthyretin amyloidosis.
Conjunctival lymphangiectasia: a novel ocular manifestation of hereditary transthyretin amyloidosis.
Considerably Unfolded Transthyretin Monomers Preceed and Exchange with Dynamically Structured Amyloid Protofibrils.
Considering amyloidosis in patients with clinically unresponsive vitreous inflammation (Oculoleptomeningeal amyloidosis in 3 individuals with transthyretin variant Tyr69His. Vol. 44[3]).
Content Validation of the ATTR Amyloidosis Patient Symptom Survey: Findings from Patient and Clinician Cognitive Debriefing Interviews.
Contribution of wild-type transthyretin to hereditary peripheral nerve amyloid.
Contributions of Animal Models to the Mechanisms and Therapies of Transthyretin Amyloidosis.
Conventional Molecular Dynamics and Metadynamics Simulation Studies of the Binding and Unbinding Mechanism of TTR Stabilizers AG10 and Tafamidis.
Correction to: A Review of Patisiran (ONPATTRO®) for the Treatment of Polyneuropathy in People with Hereditary Transthyretin Amyloidosis.
Correction to: Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis.
Corrigendum to: A new therapy for Transthyretin amyloidosis, no longer an orphan condition.
Corrigendum: Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses.
CORRIGENDUM: Utility of 99 mTc-Pyrophosphate Scintigraphy in Diagnosing Transthyretin Cardiac Amyloidosis in Real-World Practice.
Cost-Effectiveness of Tafamidis Therapy for Transthyretin Amyloid Cardiomyopathy.
Cost-effectiveness of technetium pyrophosphate scintigraphy versus heart biopsy for the diagnosis of transthyretin amyloidosis.
CRISPR-Cas9 In Vivo Gene Editing for Transthyretin Amyloidosis.
Curcumin: A multi-target disease-modifying agent for late-stage transthyretin amyloidosis.
Current and future treatment of amyloid diseases.
Current Challenges of Cardiac Amyloidosis Awareness among Romanian Cardiologists.
Current perspectives on cardiac amyloidosis.
Current Review of Leptomeningeal Amyloidosis Associated With Transthyretin Mutations.
Current treatment in cardiac amyloidosis.
Current trends in diagnosis and management of cardiac amyloidosis.
Cutaneous lymphatic amyloid deposits in "Hungarian-type" familial transthyretin amyloidosis: a case report.
Cyclodextrin, a novel therapeutic tool for suppressing amyloidogenic transthyretin misfolding in transthyretin-related amyloidosis.
Cys-10 mixed disulfide modifications exacerbate transthyretin familial variant amyloidogenicity: a likely explanation for variable clinical expression of amyloidosis and the lack of pathology in C10S/V30M transgenic mice?
Cys10 mixed disulfides make transthyretin more amyloidogenic under mildly acidic conditions.
Cysteine 10 is a key residue in amyloidogenesis of human transthyretin Val30Met.
D18G transthyretin is monomeric, aggregation prone, and not detectable in plasma and cerebrospinal fluid: a prescription for central nervous system amyloidosis?
Dangerous relationships: aortic stenosis and transthyretin cardiac amyloidosis.
Days alive and outside of hospital from diagnosis of transthyretin vs. light chain cardiac amyloidosis.
Delayed diagnosis of transthyretin amyloidosis with a novel mutation (c.210T>A) in the transthyretin gene.
Deleterious effect of right ventricular pacing in patients with cardiac transthyretin amyloidosis: potential clinical benefit of cardiac resynchronization therapy.
Demyelinating Neuropathy in a Patient Treated With Revusiran for Transthyretin (Thr60Ala) Amyloidosis.
Derivatization strategies for CE-LIF analysis of biomarkers: Toward a clinical diagnostic of familial transthyretin amyloidosis.
Description of a large cohort of Caucasian patients with V122I ATTRv amyloidosis: Neurological and cardiological features.
Design and Rationale of the Global Phase 3 NEURO-TTRansform Study of Antisense Oligonucleotide AKCEA-TTR-LRx (ION-682884-CS3) in Hereditary Transthyretin-Mediated Amyloid Polyneuropathy.
Design and Rationale of the Phase 3 ATTR-ACT Clinical Trial (Tafamidis in Transthyretin Cardiomyopathy Clinical Trial).
Design of mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and new structural templates.
Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy.
Detection of genetic variants of transthyretin by liquid chromatography-dual electrospray ionization fourier-transform ion-cyclotron-resonance mass spectrometry.
Detection of high-molecular-weight amyloid serum protein complexes using biological on-line tracer sedimentation.
Detection of serum amyloid A-derived proteins in formalin-fixed paraffin-embedded tissues: reliability of the method and expansion of its spectrum.
Determinants and Prognostic Significance of Serial Right Heart Function Changes in Patients With Cardiac Amyloidosis.
Development and Clinical Applications of Antisense Oligonucleotide Gapmers.
Development and validation of a liquid chromatography-tandem mass spectrometry method for the assay of tafamidis in rat plasma: Application to a pharmacokinetic study in rats.
Development and validation of a TTR-specific copy number screening tool, and application to potentially relevant patient cohorts.
Development of cardiomyopathy after liver transplantation in Swedish hereditary transthyretin amyloidosis (ATTR) patients.
Development of late amyloid cardiomyopathy following liver transplantation for hereditary Val30Met transthyretin amyloidosis.
Development of measures of polyneuropathy impairment in hATTR amyloidosis: From NIS to mNIS?+?7.
Development of siRNA Therapeutics for the Treatment of Liver Diseases.
Development of transgenic Caenorhabditis elegans expressing human transthyretin as a model for drug screening.
Diagnosing Transthyretin Cardiac Amyloidosis by Technetium Tc 99m Pyrophosphate: A Test in Evolution.
Diagnosis and Screening of Patients with Hereditary Transthyretin Amyloidosis (hATTR): Current Strategies and Guidelines.
Diagnosis and therapeutic approaches to transthyretin amyloidosis.
Diagnosis and treatment of cardiac amyloidosis: an interdisciplinary consensus statement.
Diagnosis and treatment of cardiac amyloidosis: position statement of the German Cardiac Society (DGK).
Diagnosis and treatment of gastrointestinal dysfunction in hereditary TTR amyloidosis.
Diagnosis and treatment of heart failure in hereditary transthyretin amyloidosis.
Diagnosis and Treatment of Hereditary Transthyretin Amyloidosis (hATTR) Polyneuropathy: Current Perspectives on Improving Patient Care.
Diagnosis and Treatment of Transthyretin Cardiac Amyloidosis. Progress and Hope.
Diagnosis of amyloid neuropathy.
Diagnosis of Amyloidosis: A Survey of Current Awareness and Clinical Challenges Among Cardiologists in Switzerland.
Diagnosis of cardiac amyloidosis by magnetic resonance imaging due to a new mutation in the transthyretin gene.
Diagnosis of cardiac amyloidosis: a systematic review on the role of imaging and biomarkers.
Diagnosis of cardiac transthyretin amyloidosis based on multimodality imaging.
Diagnosis of genetic amyloidosis through the analysis of transthyretin gene mutation using high-resolution melting.
Diagnosis of transthyretin cardiac amyloidosis with cadmium zinc telluride cameras: Is it feasible?
Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis.
Diagnostic and prognostic value of cardiac imaging in amyloidosis.
Diagnostic and prognostic value of Technetium-99m pyrophosphate uptake quantitation for transthyretin cardiac amyloidosis.
Diagnostic challenges in hereditary transthyretin amyloidosis with polyneuropathy: avoiding misdiagnosis of a treatable hereditary neuropathy.
Diagnostic delay in wild type transthyretin cardiac amyloidosis - A clinical challenge.
Diagnostic Performance of Abnormal Nulling on Cardiac Magnetic Resonance Imaging Look Locker Inversion Time Sequence in Differentiating Cardiac Amyloidosis Types.
Diagnostic performance of imaging investigations in detecting and differentiating cardiac amyloidosis: a systematic review and meta-analysis.
Diagnostic performance of transthyretin measurement in fat tissue of patients with ATTR amyloidosis.
Diagnostic utility of cardiac troponin T level in patients with cardiac amyloidosis.
Diagnostic value of cardiovascular magnetic resonance in comparison to endomyocardial biopsy in cardiac amyloidosis: a multi-centre study.
Dietary curcumin counteracts extracellular transthyretin deposition: insights on the mechanism of amyloid inhibition.
Differences in the characteristics and contemporary cardiac outcomes of patients with light-chain versus transthyretin cardiac amyloidosis.
Different NT-proBNP circulating levels for different types of cardiac amyloidosis.
Differential expression of Cathepsin E in transthyretin amyloidosis: from neuropathology to the immune system.
Differential Myocyte Responses in Patients with Cardiac Transthyretin Amyloidosis and Light-Chain Amyloidosis: A Cardiac MR Imaging Study.
Diffuse Alveolar Septal Amyloidosis with Wild-Type Transthyretin with Spontaneous Lung Hematoma.
Diffusion Tensor Cardiovascular Magnetic Resonance in Cardiac Amyloidosis.
Diflunisal for ATTR Cardiac Amyloidosis.
Diflunisal tolerability in transthyretin cardiac amyloidosis: a single center's experience.
Diphenyl-Methane Based Thyromimetic Inhibitors for Transthyretin Amyloidosis.
Diphosphonate single-photon emission computed tomography in cardiac transthyretin amyloidosis.
Direct Tissue Evaluation via Immunofluorescence: in the Diagnosis of Hereditary Transthyretin Cardiac Amyloidosis.
Discordant Findings on 18F-NaF and 99mTc-HDP Bone Scans in a Patient With ATTR Cardiac Amyloidosis.
Discordant phenotype in monozygotic female twins with Lys35Thr TTR familial amyloidotic polyneuropathy.
DISCOVERY: prevalence of transthyretin (TTR) mutations in a US-centric patient population suspected of having cardiac amyloidosis.
DISCOVERY: prevalence of transthyretin (TTR) mutations in a US-centric patient population suspected of having cardiac amyloidosis: a comment.
Disease Modifying Treatments for Transthyretin Amyloidosis.
Disease profile and differential diagnosis of hereditary transthyretin-related amyloidosis with exclusively cardiac phenotype: an Italian perspective.
Disease progression in cardiac transthyretin amyloidosis is indicated by serial calculation of National Amyloidosis Centre transthyretin amyloidosis stage.
Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
Disease-Modifying Therapy for Transthyretin Amyloidosis: Where to Start? Where to Stop?
Disease-Specific Biomarkers in Transthyretin Cardiac Amyloidosis.
Disparities, Uncertainties, and Societal Cost: Precision Medicine and Transthyretin Amyloidosis.
Disruption of blood-nerve barriers in hereditary transthyretin (ATTR) amyloidosis.
Dissecting the structure, thermodynamic stability, and aggregation properties of the A25T transthyretin (A25T-TTR) variant involved in leptomeningeal amyloidosis: identifying protein partners that co-aggregate during A25T-TTR fibrillogenesis in cerebrospinal fluid.
Dissociation of amyloid fibrils of alpha-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities.
Diuretic Dose and NYHA Functional Class Are Independent Predictors of Mortality in Patients With Transthyretin Cardiac Amyloidosis.
Domino liver transplantation: full-length transthyretin in donor and recipient patients with ATTR Val30Met amyloidosis.
Doxycycline plus tauroursodeoxycholic acid for transthyretin amyloidosis: a phase II study.
Drug Discovery and Development in Rare Diseases: Taking a Closer Look at the Tafamidis Story.
Drug discovery targeted at transthyretin cardiac amyloidosis: rational design, synthesis, and biological activity of new transthyretin amyloid inhibitors.
Early cardiac involvement in senile systemic amyloidosis: a case report.
Early changes of nerve integrity in preclinical carriers of hereditary transthyretin Ala117Ser amyloidosis with polyneuropathy.
Early data on long-term efficacy and safety of inotersen in patients with hereditary transthyretin amyloidosis: a 2-year update from the open-label extension of the NEURO-TTR trial.
Early Data on Long-term Impact of Inotersen on Quality-of-Life in Patients with Hereditary Transthyretin Amyloidosis Polyneuropathy: Open-Label Extension of NEURO-TTR.
Early destructive spondyloarthropathy from combined beta2-microglobulin and transthyretin Met30 amyloidosis in a dialysed patient.
Early Diagnosis and Outcome in Patients With Wild-Type Transthyretin Cardiac Amyloidosis.
Early diagnosis of ATTR amyloidosis through targeted follow-up of identified carriers of TTR gene mutations.
Early Impairment of Right Ventricular Morphology and Function in Transthyretin-Related Cardiac Amyloidosis.
Early onset vitreous amyloidosis in familial amyloidotic polyneuropathy with a transthyretin Glu54Gly mutation is associated with elevated vitreous VEGF.
Early Progression of Aortic Stenosis Associated With Iatrogenic Variant Transthyretin Amyloidosis After Domino Liver Transplantation.
Early skin denervation in hereditary and iatrogenic transthyretin amyloid neuropathy.
Early-Onset of Transthyretin Amyloidosis in a Young Afro-Caribbean Woman With Thr60Ala Mutation.
Echocardiographic and Biohumoral Characteristics in Patients With AL and TTR Amyloidosis at Diagnosis.
Echocardiographic and pathologic findings of wild-type transthyretin senile systemic amyloidosis developed in early 50s.
Echocardiographic phenotype and prognosis in transthyretin cardiac amyloidosis.
Editorial response to Aimo et al Quality-of-life assessment in amyloid transthyretin amyloidosis.
Editorial: Transthyretin: a small protein in the big world of amyloidoses.
Effect of age and sex differences on wild-type transthyretin amyloid formation in familial amyloidotic polyneuropathy: a proteomic approach.
Effect of cyclodextrins on transthyretin amyloid formation in transthyretin-related amyloidosis.
Effect of doxycycline and ursodeoxycholic acid on transthyretin amyloidosis.
Effect of nitric oxide in amyloid fibril formation on transthyretin-related amyloidosis.
Effects of Chronic Stress on Prefrontal Cortex Transcriptome in Mice Displaying Different Genetic Backgrounds.
Effects of liver transplantation and tafamidis in hereditary transthyretin amyloidosis caused by transthyretin Leu55Pro mutation: a case report.
Effects of sporadic transthyretin amyloidosis frequently on the gallbladder and the correlation between amyloid deposition in the gallbladder and heart: A forensic autopsy-based histopathological evaluation.
Effects of Tafamidis on Transthyretin Stabilization and Clinical Outcomes in Patients with Non-Val30Met Transthyretin Amyloidosis.
Efficacy and safety of patisiran for familial amyloidotic polyneuropathy: a phase II multi-dose study.
Efficacy of Tafamidis in Patients With Hereditary and Wild-Type Transthyretin Amyloid Cardiomyopathy: Further Analyses From ATTR-ACT.
Efficient 1-Hour Technetium-99 m Pyrophosphate Imaging Protocol for the Diagnosis of Transthyretin Cardiac Amyloidosis.
Elderly onset vitreous opacities as the initial manifestation in hereditary transthyretin (ATTR Val30Met) carries.
Electro-clinical presentation of hereditary transthyretin related amyloidosis when presenting as a polyneuropathy of unknown origin in northern France.
Elevated interleukin-6 levels are associated with impaired outcome in cardiac transthyretin amyloidosis.
Emerging Advances in the Management of Cardiac Amyloidosis.
Emerging Therapeutics for the Treatment of Light Chain and Transthyretin Amyloidosis.
Emerging Therapies for Transthyretin Cardiac Amyloidosis.
Emerging therapies in transthyretin amyloidosis - a new wave of hope after years of stagnancy?
End-stage renal failure due to transthyretin amyloidosis after liver transplantation: outcomes in 19 registry cases.
Endomyocardial Biopsy Characterization of Heart Failure With Preserved Ejection Fraction and Prevalence of Cardiac Amyloidosis.
Endoplasmic reticulum quality control regulates the fate of transthyretin variants in the cell.
Enhanced amyloidogenicity of sulfonated transthyretin in vitro, a hypothetical etiology of senile amyloidosis.
Enhanced detection of ATTR amyloid using a nanofibril-based assay.
Enhanced transthyretin tetramer stability following expression of an amyloid disease transsuppressor variant in mammalian cells.
Enthalpic Forces Correlate with the Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma.
Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.
Epigenetic profiling of Italian patients identified methylation sites associated with hereditary transthyretin amyloidosis.
Epigenomic Profiles of African-American Transthyretin Val122Ile Carriers Reveals Putatively Dysregulated Amyloid Mechanisms.
Erratum to: Monitoring effectiveness and safety of Tafamidis in transthyretin amyloidosis in Italy: a longitudinal multicenter study in a non-endemic area.
Established and candidate transthyretin amyloidosis variants identified in the Saudi population by data mining.
Establishment of an induced pluripotent stem cell line from a patient with hereditary transthyretin amyloidosis carrying transthyretin (TTR) mutation p.Phe53Val.
Establishment of an induced pluripotent stem cell line PUMCHi004-A from a hereditary transthyretin amyloid cardiomyopathy patient with transthyretin (TTR) p.Asp38Asn mutation.
Estimating cancer risk from 99mTc pyrophosphate imaging for transthyretin cardiac amyloidosis.
Estimating the Gender Distribution of Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy: A Systematic Review and Meta-Analysis.
Estimating the prevalence of allelic variants in the transthyretin gene by analysing large-scale sequencing data.
Estimation of prevalence of transthyretin (ATTR) cardiac amyloidosis in an Australian subpopulation using bone scans with echocardiography and clinical correlation.
Etiology of Amyloidosis Determines Myocardial 99mTc-DPD Uptake in Amyloidotic Cardiomyopathy.
Evaluating the binding selectivity of transthyretin amyloid fibril inhibitors in blood plasma.
Evaluation of Mortality During Long-Term Treatment with Tafamidis for Transthyretin Amyloidosis with Polyneuropathy: Clinical Trial Results up to 8.5 Years.
Evidence of the presence of amyloid substance in the blood of familial amyloidotic polyneuropathy patients with ATTR Val30Met mutation.
Evidence that glial cells attenuate G47R transthyretin accumulation in the central nervous system.
Evolution of amyloid fibrils in hereditary transthyretin amyloidosis: an ultrastructural study.
Evolutionary changes to transthyretin: structure-function relationships.
Evolving landscape in the management of transthyretin amyloidosis.
Examining the sensitivity of 18F-NaF PET for the imaging of cardiac amyloidosis.
Excisional goniotomy with Kahook Dual Blade in a patient with glaucoma secondary to Transthyretin Amyloidosis.
Exome analysis of connective tissue dysplasia: Death and rebirth of clinical genetics?
Expanding the spectrum of transthyretin amyloidosis.
Experience of patisiran with transthyretin stabilizers in patients with hereditary transthyretin-mediated amyloidosis.
Experimental Inhibition of Fibrillogenesis and Neurotoxicity by amyloid-beta (A?) and Other Disease-Related Peptides/Proteins by Plant Extracts and Herbal Compounds.
Expert consensus on the monitoring of transthyretin amyloid cardiomyopathy.
Expert Consensus Recommendations for the Suspicion and Diagnosis of Transthyretin Cardiac Amyloidosis.
Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy.
Exploration of the Misfolding Mechanism of Transthyretin Monomer: Insights from Hybrid-Resolution Simulations and Markov State Model Analysis.
EXPRESS: Riociguat for the treatment of transthyretin cardiac amyloidosis - Data from a named patient use program in Austria.
Expression of a synthetic gene encoding human transthyretin in Escherichia coli.
Expression of Amyloidogenic Transthyretin Drives Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease.
Expression, purification, and in vitro cysteine-10 modification of native sequence recombinant human transthyretin.
Extensive intracranial microbleeds in transthyretin amyloidosis.
Extracardiac 18F-florbetapir imaging in patients with systemic amyloidosis: more than hearts and minds.
Extracardiac Accumulation of Technetium-99m-Pyrophosphate in Transthyretin Cardiac Amyloidosis.
Extracardiac soft tissue uptake, evidenced on early 99mTc-HMDP SPECT/CT, helps typing cardiac amyloidosis and demonstrates high prognostic value.
Extracellular remodeling in patients with wild-type amyloidosis consuming epigallocatechin-3-gallate: preliminary results of T1 mapping by cardiac magnetic resonance imaging in a small single center study.
Factors associated with changes in serum transthyretin after treatment with tafamidis and outcomes in transthyretin cardiac amyloidosis.
Failure of Tafamidis to Halt Progression of Ala36Pro TTR Oculomeningovascular Amyloidosis.
False positive technetium-99m pyrophosphate scintigraphy in a patient with cardiac amyloidosis light chain: Case report.
False-positive bone scintigraphy denoting transthyretin amyloid in elderly hypertrophic cardiomyopathy.
Familial amyloid cardiomyopathy masquerading as chronic Guillain-Barre syndrome: things are not always what they seem.
Familial amyloid polyneuropathy type I (Portuguese): distribution and characterization of renal amyloid deposits.
Familial amyloid polyneuropathy.
Familial amyloidosis in a large Spanish kindred resulting from a D38V mutation in the transthyretin gene.
Familial amyloidosis with polyneuropathy associated with TTR Ser50Arg mutation.
Familial amyloidotic polyneuropathy and transthyretin.
Familial amyloidotic polyneuropathy type 1 in Brazil is associated with the transthyretin Val30Met variant.
Familial Amyloidotic Polyneuropathy Type 1: A Hereditary Legacy.
Familial amyloidotic polyneuropathy: a new transthyretin position 30 mutation (alanine for valine) in a family of German descent.
Familial amyloidotic polyneuropathy: protein aggregation in the peripheral nervous system.
Familial Approach in Hereditary Transthyretin Cardiac Amyloidosis.
Familial approach in hereditary transthyretin cardiac amyloidosis.
Familial ATTR amyloidosis: microalbuminuria as a predictor of symptomatic disease and clinical nephropathy.
Familial leptomeningeal amyloidosis with a transthyretin variant Asp18Gly representing repeated subarachnoid haemorrhages with superficial siderosis.
Familial meningocerebrovascular amyloidosis, Hungarian type, with mutant transthyretin (TTR Asp18Gly)
Familial Oculo-Leptomeningeal Transthyretin Amyloidosis Caused by Leu55Arg Mutation.
Familial Transthyretin Amyloidosis with Variant Asp38Ala Presenting with Orthostatic Hypotension and Chronic Diarrhea.
Familial vitreous amyloidosis resulting from transthyretin variant Gly83Arg.
Family studies of the genetic abnormality in transthyretin (prealbumin) in Portuguese patients with familial amyloidotic polyneuropathy.
Fatal cerebral haemorrhage after liver transplantation in a patient with transthyretin variant (gly53glu) amyloidosis.
FDA approves patisiran to treat hereditary transthyretin amyloidosis.
Feasibility of assessing progression of transthyretin amyloid polyneuropathy using nerve conduction studies: Findings from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience.
Fecal calprotectin concentrations in patients with hereditary transthyretin amyloidosis and gastrointestinal symptoms.
Fecal calprotectin levels are elevated in transthyretin amyloidosis patients with gastrointestinal manifestations.
Fibril in senile systemic amyloidosis is derived from normal transthyretin.
Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis.
First in man: gene editing for the treatment of transthyretin amyloidosis.
First report of a rare mutation in a Polish patient with painful late-onset transthyretin amyloidosis.
First-in-Human Study of AG10, a Novel, Oral, Specific, Selective, and Potent Transthyretin Stabilizer for the Treatment of Transthyretin Amyloidosis: A Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study in Healthy Adult Volunteers.
Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis.
Fluorotryptophan incorporation modulates the structure and stability of transthyretin in a site-specific manner.
Founder effect of the Glu89Gln TTR mutation in the Bulgarian population.
Frailty in Wild-Type Transthyretin Cardiac Amyloidosis: The Tip of the Iceberg.
Frequency and genetic background of the position 122 (Val----Ile) variant transthyretin gene in the black population.
Frequency of ClinVar Pathogenic Variants in Chronic Kidney Disease Patients Surveyed for Return of Research Results at a Cleveland Public Hospital.
FRET studies of various conformational states adopted by transthyretin.
From Clinical Clues to Final Diagnosis: The Return of Detective Work to Clinical Medicine in Cardiac Amyloidosis.
From hypertrophic cardiomyopathy to transthyretin amyloidosis: an unusual case and challenging diagnosis.
From renal amyloid deposits to the identification of the culprit genes.
Functional Amyloid Signaling via the Inflammasome, Necrosome, and Signalosome: New Therapeutic Targets in Heart Failure.
Functional variation of the transthyretin gene among human populations and its correlation with amyloidosis phenotypes.
Gastric emptying in hereditary transthyretin amyloidosis: the impact of autonomic neuropathy.
Gastric peroral endoscopic myotomy for transthyretin amyloidosis gastroparesis.
Gastrointestinal amyloidosis associated with transthyretin Phe64Ser mutation.
Gastrointestinal Manifestations in Hereditary Transthyretin Amyloidosis associated with Glu89Gln Mutation.
Gastrointestinal Manifestations in Hereditary Transthyretin Amyloidosis: a Single-Centre Experience.
Gastrointestinal Tract Amyloidosis Presenting With Pneumatosis Intestinalis.
Gateway and journey of patients with cardiac amyloidosis.
Gene expression profile in hereditary transthyretin amyloidosis: differences in targeted and source organs.
Gene-targeting pharmaceuticals for single-gene disorders.
Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis.
Genetic and clinical characteristics of hereditary transthyretin amyloidosis in endemic and non-endemic areas: experience from a single-referral center in Japan.
Genetic anticipation in Portuguese kindreds with familial amyloidotic polyneuropathy is unlikely to be caused by triplet repeat expansions.
Genetic microheterogeneity of human transthyretin detected by IEF.
Genetic neuromuscular disorders: living the era of a therapeutic revolution. Part 1: peripheral neuropathies.
Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy.
Genetic testing improves identification of transthyretin amyloid (ATTR) subtype in cardiac amyloidosis.
Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt).
Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis.
Genomic Screening Identifies Individuals at High Risk for Hereditary Transthyretin Amyloidosis.
Genotype and Phenotype of Transthyretin Cardiac Amyloidosis: THAOS (Transthyretin Amyloid Outcome Survey).
Genotype, echocardiography, and survival in familial transthyretin amyloidosis.
Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study.
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report.
Gross hematuria: An unusual presenting symptom of systemic wild-type transthyretinamyloidosis.
Guideline of transthyretin-related hereditary amyloidosis for clinicians.
hATTR Pathology: Nerve Biopsy Results from Italian Referral Centers.
Health and economic impact of the correct diagnosis of transthyretin cardiac amyloidosis in Spain.
Health-related quality of life in hereditary transthyretin amyloidosis polyneuropathy: a prospective, observational study.
Heart complications in familial transthyretin amyloidosis: impact of age and gender.
Heart failure and cardiac involvement as isolated manifestation of familial form of transthyretin amyloidosis resulting from Val30Met mutation with no clinical signs of polyneuropathy.
Heart failure caused by a novel amyloidogenic mutation of the transthyretin gene: ATTR Ala45Ser.
Heart Failure Complicated by Alveolar Hemorrhage due to Vascular Collapse and Amyloid Deposits in Wild-Type Transthyretin Amyloidosis.
Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study.
Heart failure with preserved ejection fraction, atrial fibrillation, and the role of senile amyloidosis.
Heart transplantation for homozygous familial transthyretin (TTR) V122I cardiac amyloidosis.
Heart transplantation in a 68-year-old patient with senile systemic amyloidosis.
Heart transplantation in cardiac amyloidosis.
Heavy and light chain (AHL)-type cardiac amyloidosis: first histopathologic-proven case illustrating involvement of the heart.
Hemodynamic Profiles and Their Prognostic Relevance in Cardiac Amyloidosis.
Hepatocyte-like cells reveal novel role of SERPINA1 in transthyretin amyloidosis.
Hepatocyte-Targeted Delivery of siRNA Polyplex with PEG-Modified Lactosylated Dendrimer/Cyclodextrin Conjugates for Transthyretin-Related Amyloidosis Therapy.
Hereditary amyloid cardiomyopathy caused by a variant apolipoprotein A1.
Hereditary ATTR Amyloidosis in Austria: Prevalence and Epidemiological Hot Spots.
Hereditary ATTR Amyloidosis with Cardiomyopathy Caused by the Novel Variant Transthyretin Y114S (p.Y134S).
Hereditary ATTR amyloidosis: a single-institution experience with 266 patients.
Hereditary cardiac amyloidosis associated with Pro24Ser transthyretin mutation: a case report.
Hereditary cardiac amyloidosis associated with the transthyretin Ile122 mutation in a white man.
Hereditary transthyretin amyloidosis associated with a transthyretin variant Thr59Arg.
Hereditary transthyretin amyloidosis caused by the rare Phe33Leu mutation.
Hereditary transthyretin amyloidosis from a Scandinavian perspective.
Hereditary Transthyretin Amyloidosis in Eight Chinese Families.
Hereditary transthyretin amyloidosis in mainland China: a unicentric retrospective study.
Hereditary transthyretin amyloidosis in multi-ethnic Malaysians.
Hereditary transthyretin amyloidosis overview.
Hereditary Transthyretin Amyloidosis- Clinical and Genetic Characteristics of a Multiracial South-East Asian Cohort in Singapore.
Hereditary transthyretin amyloidosis: a model of medical progress for a fatal disease.
Hereditary transthyretin amyloidosis: baseline characteristics of patients in the NEURO-TTR trial.
Hereditary Transthyretin Amyloidosis: Clinical Presentation and Management Updates.
Hereditary transthyretin amyloidosis: current treatment.
Hereditary transthyretin amyloidosis: molecular basis and therapeutical strategies.
Hereditary Transthyretin Cardiac Amyloidosis in Refractory Spinal Canal Stenosis: Genetic and Pathologic Analysis.
High prevalence of heart failure with reduced ejection fraction in patients with transthyretin cardiac amyloidosis.
High prevalence of wild-type transthyretin deposition in patients with idiopathic carpal tunnel syndrome: a common cause of carpal tunnel syndrome in the elderly.
Highly selective leptomeningeal amyloidosis with transthyretin variant Ala25Thr.
Hip and knee arthroplasty are common among patients with transthyretin cardiac amyloidosis, occurring years before cardiac amyloid diagnosis: can we identify affected patients earlier?
Homozygosity for the V122I mutation in transthyretin is associated with earlier onset of cardiac amyloidosis in the African American population in the seventh decade of life.
Homozygous transthyretin mutation in an African American Male.
How to Identify Transthyretin Cardiac Amyloidosis at an Early Stage.
How to Image Cardiac Amyloidosis: A Practical Approach.
How to suspect transthyretin cardiac amyloidosis during daily clinical practice.
How your ears can tell what is hidden in your heart: wild-type transthyretin amyloidosis as potential cause of sensorineural hearing loss inelderly-AmyloDEAFNESS pilot study.
Human TTRV30M localization within podocytes in a transgenic mouse model of transthyretin related amyloidosis: does the environment play a role?
Human-murine transthyretin heterotetramers are kinetically stable and non-amyloidogenic. A lesson in the generation of transgenic models of diseases involving oligomeric proteins.
Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease.
Hydrogen-bond network and pH sensitivity in transthyretin: Neutron crystal structure of human transthyretin.
Hydroxymethylene diphosphonate for imaging transthyretin cardiac amyloidosis.
Iatrogenic amyloid polyneuropathy after domino liver transplantation.
Identification of a novel transthyretin Thr59Lys/Arg104His. A case of compound heterozygosity in a Chinese patient diagnosed with familial transthyretin amyloidosis.
Identification of a novel TTR Gly67Glu mutant and the first case series of familial transthyretin amyloidosis in Hong Kong Chinese.
Identification of prognostic markers in transthyretin and AL cardiac amyloidosis.
Identification of S-sulfonation and S-thiolation of a novel transthyretin Phe33Cys variant from a patient diagnosed with familial transthyretin amyloidosis.
Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model.
Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction: Potential Novel Therapeutics for Macular Degeneration, Transthyretin Amyloidosis, and Their Common Age-Related Comorbidities.
Identification of Wild-Type Transthyretin Cardiac Amyloidosis by Quantifying Myocardial Extracellular Volume Using Cardiac Computed Tomography in Atrial Arrhythmias.
Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging.
Imaging cardiac innervation in hereditary transthyretin (ATTRm) amyloidosis: A marker for neuropathy or cardiomyopathy in case of heart failure?
Imaging in systemic amyloidosis.
Imaging of cardiac amyloidosis by (99m)Tc-PYP scintigraphy.
Imaging Techniques As An Aid In The Early Detection Of Cardiac Amyloidosis.
Immunoaffinity chromatographic and immunoprecipitation methods combined with mass spectrometry for characterization of circulating transthyretin.
Immunogenicity Assessment of Inotersen, a 2'-O-(2-Methoxyethyl) Antisense Oligonucleotide in Animals and Humans: Effect on Pharmacokinetics, Pharmacodynamics, and Safety.
Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients.
Immunostaining images of vitreous transthyretin amyloid.
Impact of afterload and infiltration on coexisting aortic stenosis and transthyretin amyloidosis.
Impact of age and amyloidosis on thiol conjugation of transthyretin in hereditary transthyretin amyloidosis.
Impact of aging on the progression of neuropathy after liver transplantation in transthyretin Val30Met amyloidosis.
Impact of clinical and echocardiographic characteristics on occurrence of cardiac events in cardiac amyloidosis as proven by endomyocardial biopsy.
Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses.
Impact of Genetic Testing in Transthyretin (ATTR) Cardiac Amyloidosis.
Impact of genotype and phenotype on cardiac biomarkers in patients with transthyretin amyloidosis - Report from the Transthyretin Amyloidosis Outcome Survey (THAOS).
Impact of liver transplantation on cardiac autonomic denervation in familial amyloid polyneuropathy.
Impact of liver transplantation on familial amyloidotic polyneuropathy (FAP) patients' symptoms and complications.
Impact of liver transplantation on the natural history of oculopathy in Portuguese patients with transthyretin (V30M) amyloidosis.
Impact of Non-Cardiac Clinicopathologic Characteristics on Survival in Transthyretin Amyloid Polyneuropathy.
Impaired in vitro growth response of plasma-treated cardiomyocytes predicts poor outcome in patients with transthyretin amyloidosis.
Impairment of autophagy by TTR V30M aggregates: in vivo reversal by TUDCA and curcumin.
Implementing genomic screening in diverse populations.
Importance of Genetic Testing in the Diagnosis of Transthyretin Cardiac Amyloidosis.
Improved electrochemical detection of a transthyretin synthetic peptide in the nanomolar range with a two-electrode system integrated in a glass/PDMS microchip.
Improved outcomes after heart transplantation for cardiac amyloidosis in the modern era.
Improving strategies for the diagnosis of cardiac amyloidosis.
In silico analysis of TTR gene (coding and non-coding regions, and interactive network) and its implications in transthyretin-related amyloidosis.
In the midst of a dangerous intersection with unclear therapeutic strategies: a challenging case of severe aortic stenosis.
In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis.
In vivo molecular imaging of peripheral amyloidosis using heparin-binding peptides.
Inborn errors of apolipoprotein A-I metabolism: implications for disease, research and development.
Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele.
Inconsistency between hepatic expression and serum concentration of transthyretin in mice humanized at the transthyretin locus.
Increased Risk of Multiple Outpatient Surgeries in African-American Carriers of Transthyretin Val122Ile Mutation Is Modulated by Non-Coding Variants.
Increased thickness of lumbar spine ligamentum flavum in wild-type transthyretin amyloidosis.
Increasing the accuracy of proteomic typing by decellularisation of amyloid tissue biopsies.
Indications and diagnostic yield of endomyocardial biopsies for unexplained cardiomyopathy, a single center experience.
Indications for liver transplantation in patients with amyloidosis: a single-center experience with 11 cases.
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis.
Ineffectiveness of dialysis in transthyretin (TTR) clearance in familial amyloid polyneuropathy type I, in spite of lower stability of the TTR Met30 variant.
Inflammatory and Molecular Pathways in Heart Failure-Ischemia, HFpEF and Transthyretin Cardiac Amyloidosis.
Inflammatory profiling of patients with familial amyloid polyneuropathy.
Inhibiting transthyretin amyloid fibril formation via protein stabilization.
Inhibition of human transthyretin aggregation by non-steroidal anti-inflammatory compounds: a structural and thermodynamic analysis.
Inhibition of the Amyloidogenesis of Transthyretin by Natural Products and Synthetic Compounds.
Inhibition of transthyretin-met30 expression using Inosine(15.1)-Hammerhead ribozymes in cell culture.
Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.
Inhibitory activities of propolis and its promising component, caffeic acid phenethyl ester, against amyloidogenesis of human transthyretin.
Inotersen (transthyretin-specific antisense oligonucleotide) for treatment of transthyretin amyloidosis.
Inotersen for the Treatment of Hereditary Transthyretin Amyloidosis.
Inotersen preserves or improves quality of life in hereditary transthyretin amyloidosis.
Inotersen therapy of transthyretin amyloid cardiomyopathy.
Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis.
Inotersen: First Global Approval.
Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis.
Inotropic myocardial reserve deficiency is the predominant feature of exercise haemodynamics in cardiac amyloidosis.
Integrated diagnostic approach to wild-type transthyretin cardiac amyloidosis with the use of high-sensitivity cardiac troponin T measurement and 99mTc-pyrophosphate scintigraphy.
Inter-observer reproducibility and intra-observer repeatability in 99mTc-pyrophosphate scan interpretation for diagnosis of transthyretin cardiac amyloidosis.
Interactions amongst plasma retinol-binding protein, transthyretin and their ligands: implications in vitamin A homeostasis and transthyretin amyloidosis.
Interleukin-1 signaling pathway as a therapeutic target in transthyretin amyloidosis.
Intermediate-term outcomes of heart transplantation for cardiac amyloidosis in the current era.
Interpreting technetium-99m pyrophosphate cardiac scans to diagnose transthyretin cardiac amyloidosis: Need for due diligence.
Interstitial amyloidosis in sporadic inclusion body myositis.
Intracardiac thrombosis and anticoagulation therapy in cardiac amyloidosis.
Intracranial and systemic manifestations of familial leptomeningeal amyloidosis, as seen on CT and MRI.
Intramyocardial inflammation predicts adverse outcome in patients with cardiac AL amyloidosis.
Intrinsic versus mutation dependent instability/flexibility: a comparative analysis of the structure and dynamics of wild-type transthyretin and its pathogenic variants.
Investigation into thiol conjugation of transthyretin in hereditary transthyretin amyloidosis.
Investigation of AGE, their receptor and NF-kappaB activation and apoptosis in patients with ATTR and Gelsolin amyloidosis.
Iodination of salicylic acid improves its binding to transthyretin.
Is Transthyretin a Regulator of Ubc9 SUMOylation?
Isolated atrial amyloidosis and the importance of molecular classification.
Isolated atrial amyloidosis suspected by electrophysiological voltage mapping and diagnosed by 99m Tc-DPD scintigraphy.
Isolated heart transplantation for familial transthyretin (TTR) V122I cardiac amyloidosis.
Isolated vitreoretinal amyloidosis in the absence of transthyretin mutations.
Keys to early diagnosis of cardiac amyloidosis: red flags from clinical, laboratory and imaging findings.
Kind and distribution of cutaneous sensation loss in hereditary transthyretin amyloidosis with polyneuropathy.
Kinetic analysis of the multistep aggregation pathway of human transthyretin.
Kinetic assay for high-throughput screening of in vitro transthyretin amyloid fibrillogenesis inhibitors.
Kinetic stabilization of an oligomeric protein under physiological conditions demonstrated by a lack of subunit exchange: implications for transthyretin amyloidosis.
L55P transthyretin accelerates subunit exchange and leads to rapid formation of hybrid tetramers.
Laboratory assessment of transthyretin amyloidosis.
Late-onset hereditary ATTR V30M amyloidosis with polyneuropathy: Characterization of Brazilian subjects from the THAOS registry.
Late-onset peripheral neuropathy in patients with wild type transthyretin amyloidosis (wtATTR).
Latent Class Analysis to Classify Patients with Transthyretin Amyloidosis by Signs and Symptoms.
Leading RNA Interference Therapeutics Part 1: Silencing Hereditary Transthyretin Amyloidosis, with a Focus on Patisiran.
LEFT ATRIAL FUNCTION AND VOLUME BY MAGNETIC RESONANCE IN PATIENTS WITH HEREDITARY AMYLOIDOSIS.
Left Atrial Morphology, Size and Function in Patients With Transthyretin Cardiac Amyloidosis and Primary Hypertrophic Cardiomyopathy?- Comparative Strain Imaging Study.
Left atrial structure and function in cardiac amyloidosis.
Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block.
Left Ventricular Structure and Function in TTR-Related versus AL Cardiac Amyloidosis.
Length-dependent truncal A?-fiber dysfunction in hereditary transthyretin amyloidosis: An intra-epidermal electrical stimulation study.
Leukocyte Chemotactic Factor 2 (LECT2)-Associated Renal Amyloidosis: A Case Series.
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data.
Light chain and transthyretin cardiac amyloidosis: Clinical characteristics, natural history and prognostic factors.
Light-chain and transthyretin cardiac amyloidosis in severe aortic stenosis: prevalence, screening possibilities, and outcome.
Light-chain cardiac amyloidosis.
Lipid Nanoparticle Technology for Clinical Translation of siRNA Therapeutics.
Liver biopsy discloses a new apolipoprotein A-I hereditary amyloidosis in several unrelated Italian families.
Liver transplantation and transthyretin amyloidosis.
Liver transplantation for familial amyloidotic polyneuropathy in Australia.
Liver transplantation for hereditary transthyretin amyloidosis.
Liver Transplantation for Hereditary Transthyretin Amyloidosis: After 20 Years Still the Best Therapeutic Alternative?
Liver transplantation in familial amyloidotic polyneuropathy. Follow-up of the first 20 Swedish patients.
Liver transplantation in transthyretin amyloidoses. When the neurological benefit outweighs the risk.
Liver transplantation in transthyretin amyloidosis: Characteristics and management related to kidney disease.
Liver transplantation in transthyretin amyloidosis: Issues and challenges.
Localized amyloidosis: A diagnostic pitfall in breast pathology.
Long-term follow-up of survival of liver transplant recipients with familial amyloid polyneuropathy (Portuguese type).
Long-term outcome in patients treated with combined heart and liver transplantation for familial amyloidotic cardiomyopathy.
Long-term outcome of patients with hereditary transthyretin V30M amyloidosis with polyneuropathy after liver transplantation.
Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study.
Loss of gastric interstitial cells of Cajal in patients with hereditary transthyretin amyloidosis.
Low plasma apolipoprotein AII levels in human and mouse amyloidosis with mutant transthyretin (Met-30) gene.
Low Prevalence of Clinically Apparent Cardiac Amyloidosis Among Carriers of Transthyretin V122I Variant in a Large Electronic Medical Record.
Low Sensitivity of Bone Scintigraphy in Detecting Phe64Leu Mutation-Related Transthyretin Cardiac Amyloidosis.
Lumbosacral stenosis in Labrador retriever military working dogs - an exomic exploratory study.
Lysozyme amyloidosis: report of 4 cases and a review of the literature.
Macroglossia - not always AL amyloidosis.
Magnetic Resonance in Transthyretin Cardiac Amyloidosis.
Magnetization transfer ratio quantifies polyneuropathy in hereditary transthyretin amyloidosis.
Management of Cardiac Amyloidosis: Do's and Don'ts.
Management of complications of cardiac amyloidosis: 10 questions and answers.
Management of gastrointestinal complications in hereditary transthyretin amyloidosis: a single-center experience over 40 years.
Management Strategies for Atrial Fibrillation and Flutter in Patients with Transthyretin Cardiac Amyloidosis.
Marked Systemic Amyloid Angiopathy in Patients With Val 107 Transthyretin Mutation.
Markers of nutritional status and inflammation in transthyretin cardiac amyloidosis: association with outcomes and the clinical phenotype.
Mass Spectrometric-Based Proteomic Analysis of Amyloid Neuropathy Type in Nerve Tissue.
Massive leptomeningeal amyloidosis associated with a Val30Met transthyretin gene.
Matrix metalloproteinases and their tissue inhibitors in cardiac amyloidosis: relationship to structural, functional myocardial changes and to light chain amyloid deposition.
Measurement of myocardial amyloid deposition in systemic amyloidosis: insights from cardiovascular magnetic resonance imaging.
Mechanism of Action and Clinical Application of Tafamidis in Hereditary Transthyretin Amyloidosis.
Mechanisms of heart failure in transthyretin vs. light chain amyloidosis.
Mechanisms of transthyretin aggregation and toxicity.
Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations.
Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs.
Medullary amyloidosis associated with apolipoprotein A-IV deposition.
Meningocerebrovascular amyloidosis associated with a novel transthyretin mis-sense mutation at codon 18 (TTRD 18G)
Metabolic turn over of amyloid fibrils and post-treatment regression of amyloid deposits in systemic amyloidosis with polyneuropathy.
Metabolism of amyloid proteins.
Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis.
Methods to evaluate the inhibition of TTR fibrillogenesis induced by small ligands.
Misdiagnosis of hereditary amyloidosis as AL (primary) amyloidosis.
Misfolded transthyretin causes behavioral changes in a Drosophila model for transthyretin-associated amyloidosis.
Mispacking of the Phe87 side chain reduces the kinetic stability of human transthyretin.
Mitochondrial haplogroup is associated with the phenotype of familial amyloidosis with polyneuropathy in Swedish and French patients.
mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin-mediated amyloidosis.
Modeling familial amyloidotic polyneuropathy (Transthyretin V30M) in Drosophila melanogaster.
Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity.
Modulating inhibitors of transthyretin fibrillogenesis via sulfation: Polychlorinated biphenyl sulfates as models.
Modulation of the Mechanisms Driving Transthyretin Amyloidosis.
Molecular Imaging of Cardiac Amyloidosis.
Molecular Tweezers Targeting Transthyretin Amyloidosis.
Monitoring effectiveness and safety of Tafamidis in transthyretin amyloidosis in Italy: a longitudinal multicenter study in a non-endemic area.
Monitoring of asymptomatic family members at risk of hereditary transthyretin amyloidosis for early intervention with disease-modifying therapies.
Monitoring treatment response to tafamidis by serial native T1 and extracellular volume in transthyretin amyloid cardiomyopathy.
Monoclonal Gammopathy of Uncertain Significance and Transthyretin Cardiac Amyloidosis.
Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR).
Most recent common ancestor of TTR Val30Met mutation in Italian population and its potential role in genotype-phenotype correlation.
Mucocutaneous manifestations in systemic amyloidosis A retrospective analytical study in a tertiary care center.
Multicenter Study of Planar Technetium 99m Pyrophosphate Cardiac Imaging: Predicting Survival for Patients With ATTR Cardiac Amyloidosis.
Multidisciplinary Approaches for Transthyretin Amyloidosis.
Multimodality Imaging in Cardiac Amyloidosis.
Multimodality Imaging of Cardiac Transthyretin Amyloidosis 16 years after a Domino Liver Transplantation.
Multisystemic Disease Modeling of Liver-Derived Protein Folding Disorders Using Induced Pluripotent Stem Cells (iPSCs).
Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery.
Mutation p.G83R in the transthyretin gene is associated with hereditary vitreous amyloidosis in Han Chinese families.
Myocardial Amyloidosis: The Exemplar Interstitial Disease.
Myocardial Contraction Fraction by M-Mode Echocardiography Is Superior to Ejection Fraction in Predicting Mortality in Transthyretin Amyloidosis.
Myocardial Edema and Prognosis in Amyloidosis.
Myocardial hypertrophy and function are related to age at onset in familial amyloidotic polyneuropathy.
Myocardial native T2 measurement to differentiate light-chain and transthyretin cardiac amyloidosis and assess prognosis.
Myocardial Oxygen Consumption and Efficiency in Patients With Cardiac Amyloidosis.
National patterns in imaging utilization for diagnosis of cardiac amyloidosis: A focus on Tc99m-pyrophosphate scintigraphy.
Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses.
Native state stabilization by NSAIDs inhibits transthyretin amyloidogenesis from the most common familial disease variants.
Native T1 and Extracellular Volume in Transthyretin Amyloidosis.
Native T1 mapping in transthyretin amyloidosis.
Natural compounds as inhibitors of transthyretin amyloidosis and neuroprotective agents: analysis of structural data for future drug design.
Natural history and impact of treatment with tafamidis on major cardiovascular outcome-free survival time in a cohort of patients with transthyretin amyloidosis.
Natural History of Wild-Type Transthyretin Cardiac Amyloidosis and Risk Stratification Using a Novel Staging System.
Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis.
Negative bone scintigraphy in wild-type transthyretin cardiac amyloidosis.
Nerve ultrasonography features in hereditary transthyretin amyloidosis with V30M mutation and polyneuropathy.
Nerve ultrasonography findings as possible pitfall in differential diagnosis between hereditary transthyretin amyloidosis with polyneuropathy and chronic inflammatory demyelinating polyneuropathy.
Nerve ultrasound in hereditary transthyretin amyloidosis: red flags and possible progression biomarkers.
Neuroarthropathy secondary to transthyretin amyloidosis (ATTR V30M).
Neurofilament light chain, a biomarker for polyneuropathy in systemic amyloidosis.
Neuromuscular amyloidosis: Unmasking the master of disguise.
Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?
Neuropathy Associated with Systemic Amyloidosis.
Neuropathy symptom and change: Inotersen treatment of hereditary transthyretin amyloidosis.
Neuroradiologic and clinicopathologic features of oculoleptomeningeal type amyloidosis.
Neutron diffraction experiment with the Y116S variant of transthyretin using iBIX at J-PARC: application of a new integration method.
Neutrophil proteases associated with amyloid fibrils.
New data on the genetic profile and penetrance of hereditary Val30Met transthyretin amyloidosis in Sweden.
New effective treatment options reinforce disease awareness: the case of transthyretin cardiac amyloidosis.
New insights into the clinical evaluation of hereditary transthyretin amyloidosis patients: a single center's experience.
New Medications in the Treatment of Hereditary Transthyretin Amyloidosis.
New pathological insights into cardiac amyloidosis: implications for non-invasive diagnosis.
New sequence variants in patients affected by amyloidosis show transthyretin instability by isoelectric focusing.
New simple and quick method to analyze serum variant transthyretins: direct MALDI method for the screening of hereditary transthyretin amyloidosis.
New structural information and update on liver transplantation in transthyretin-associated amyloidosis. Report from the 4th International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders & the 3rd International Workshop on Liver Transplantation in Familial Amyloid Polyneuropathy, Umeå Sweden, June 1999.
Newer Therapies for Amyloid Cardiomyopathy.
No association between apolipoprotein E epsilon4 allele and the age of onset in type I familial amyloid polyneuropathy.
No Association Between CHADS-VASc Score and Left Atrial Appendage Thrombus in Patients With Transthyretin Amyloidosis.
Nodular cutaneous amyloidosis and carpal tunnel syndrome due to the amyloidogenic transthyretin His 114 variant.
Nodular senile pulmonary amyloidosis: a unique case confirmed by immunohistochemistry, mass spectrometry, and genetic study.
Non-cardiac biopsy sites with high frequency of transthyretin amyloidosis.
Non-cardiac uptake of technetium-99m pyrophosphate in transthyretin cardiac amyloidosis.
Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.
Non-invasive cardiac imaging methods in transthyretin amyloidosis.
Non-invasive detection and differentiation of cardiac amyloidosis using 99mTc-pyrophosphate scintigraphy and 11C-Pittsburgh compound B PET imaging.
Non-invasive evaluation of the myocardial substrate of cardiac amyloidosis by gadolinium cardiac magnetic resonance.
Non-invasive predictors of survival in cardiac amyloidosis.
Non-senile wild-type transthyretin systemic amyloidosis presenting as bilateral carpal tunnel syndrome.
Non-Val30Met mutation, septal hypertrophy, and cardiac denervation in patients with mutant transthyretin amyloidosis.
Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.
Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission.
Noncontrast Magnetic Resonance for the Diagnosis of Cardiac Amyloidosis.
Noninvasive Detection of Cardiac Amyloid With 11C-Pittsburgh Compound B PET/CT and 99mTc-PYP Scintigraphy.
Noninvasive detection of cardiac involvement in patients with hereditary transthyretin associated amyloidosis using cardiac magnetic resonance imaging: a prospective study.
Noninvasive diagnosis of hereditary transthyretin-related cardiac amyloidosis: A case report.
Noninvasive Diagnostic Modalities in an Isolated Case of Cardiac Amyloidosis.
Noninvasive etiologic diagnosis of cardiac amyloidosis using 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid scintigraphy.
Noninvasive Mapping of the Electrophysiological Substrate in Cardiac Amyloidosis and Its Relationship to Structural Abnormalities.
Noninvasive Risk Stratification of Patients With Transthyretin Amyloidosis.
Normal scores of deep breathing tests: beware of dysrhythmia in transthyretin amyloidosis.
Normal transthyretin and synthetic transthyretin fragments form amyloid-like fibrils in vitro.
Not All Heart Uptakes on 99mTc-DPD Scintigraphy Are Amyloidosis: Chloroquine-Induced Cardiomyopathy.
Novel Antibody for the Treatment of Transthyretin Amyloidosis.
Novel Cardiovascular Magnetic Resonance Model to Distinguish Immunoglobulin Light Chain From Transthyretin Cardiac Amyloidosis.
Novel conformation-specific monoclonal antibodies against amyloidogenic forms of transthyretin.
Novel drugs targeting transthyretin amyloidosis.
Novel insights into rare cardiomyopathies: arrhythmogenic cardiomyopathy, non-compaction, and transthyretin amyloidosis.
Novel methods for detecting amyloidogenic proteins in transthyretin related amyloidosis.
Novel pharmacotherapies for cardiac amyloidosis.
Novel screening for transthyretin amyloidosis by using fat ultrasonography.
Novel transthyretin missense mutation (Thr34) in an Italian family with hereditary amyloidosis.
Novel variant transthyretin gene (Ser50 to Ile) in familial cardiac amyloidosis.
Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol-binding protein recognition.
Nuclear Imaging for Cardiac Amyloidosis: Bone Scan, SPECT/CT, and Amyloid-Targeting PET.
Nuclear Imaging for the Diagnosis of Cardiac Amyloidosis in 2021.
Nuclear tracers for transthyretin cardiac amyloidosis: time to bone up?
Occult Transthyretin Cardiac Amyloid in Severe Calcific Aortic Stenosis: Prevalence and Prognosis in Patients Undergoing Surgical Aortic Valve Replacement.
Occurrence factors and clinical picture of iatrogenic transthyretin amyloidosis after domino liver transplantation.
Ocular amyloidosis, with special reference to the hereditary forms with vitreous involvement.
Ocular angiographic features in Japanese patients with Val30Met hereditary transthyretin amyloidosis.
Ocular Involvement in Hereditary Amyloidosis.
Ocular Involvement in Hereditary Transthyretin Amyloidosis: A Case Series Describing Novel Potential Biomarkers.
Ocular manifestations in hereditary transthyretin Gly67Glu amyloidosis.
OCULAR MANIFESTATIONS OF ASP38ALA AND THR59LYS FAMILIAL TRANSTHYRETIN AMYLOIDOSIS.
Ocular Manifestations of Familial Transthyretin Amyloidosis.
Oculoleptomeningeal amyloidosis associated with a new transthyretin variant Ser64.
Oculoleptomeningeal Amyloidosis associated with transthyretin Leu12Pro in an African patient.
Oculoleptomeningeal Amyloidosis Due to Transthyretin p.Y89H (Y69H) Variant.
Oculoleptomeningeal amyloidosis in 3 individuals with the transthyretin variant Tyr69His.
Oculoleptomeningeal amyloidosis in a large kindred with a new transthyretin variant Tyr69His.
Oculoleptomeningeal amyloidosis in a patient with a TTR Val30Gly mutation in the transthyretin gene.
Oculoleptomeningeal Amyloidosis Secondary to the Rare Transthyretin c.381T>G (p.Ile127Met) Mutation.
Old men and thickened hearts.
Oligomeric TTR V30M aggregates compromise cell viability, erythropoietin gene expression and promoter activity in the human hepatoma cell line Hep3B.
Oligonucleotide Drugs for Transthyretin Amyloidosis.
On-a-chip tryptic digestion of transthyretin: a step toward an integrated microfluidic system for the follow-up of familial transthyretin amyloidosis.
On-line immunoaffinity solid-phase extraction capillary electrophoresis mass spectrometry using Fab´antibody fragments for the analysis of serum transthyretin.
One mutation, two distinct disease variants: unravelling the impact of transthyretin amyloid fibril composition.
Optimization of Serum Immunoglobulin Free Light Chain Analysis for Subclassification of Cardiac Amyloidosis.
Optimizing 99mTc-DPD scintigraphy: Adding value to the diagnosis and treatment of cardiac transthyretin amyloidosis.
Origin of sporadic late-onset hereditary ATTR Val30Met amyloidosis in Japan.
Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management.
Orthotopic liver transplantation for familial amyloidotic polyneuropathy: a pathological study.
Osteo-articular manifestations of amyloidosis.
Ostertag revisited: the inherited systemic amyloidoses without neuropathy.
Outcome in patients treated with isolated liver transplantation for familial transthyretin amyloidosis to prevent cardiomyopathy.
Outcome of exercise electrocardiography in familial amyloidotic polyneuropathy patients, Portuguese type, under evaluation for liver transplantation.
Outcome of gastric emptying and gastrointestinal symptoms after liver transplantation for hereditary transthyretin amyloidosis.
Outcome of liver transplantation for transthyretin amyloidosis: follow-up of Japanese familial amyloidotic polyneuropathy patients.
Outcomes After Cardiac Transplant for Wild Type Transthyretin Amyloidosis.
Outcomes in patients with cardiac amyloidosis and implantable cardioverter-defibrillator.
Outcomes in Patients With Cardiac Amyloidosis Undergoing Heart Transplantation.
Outcomes of Patients With Familial Transthyretin Amyloidosis After Liver Transplantation.
Overview of treatments used in transthyretin-related hereditary amyloidosis: a systematic review.
Paraproteinemias and Peripheral Nerve Disease.
Parenteral nutrition improves nutritional status, autonomic symptoms and quality of life in transthyretin amyloid polyneuropathy.
Pathogenesis of and therapeutic strategies to ameliorate the transthyretin amyloidoses.
Pathogenesis of transthyretin amyloidosis.
Pathological changes long after liver transplantation in a familial amyloidotic polyneuropathy patient.
Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis.
Patient and family experience with transthyretin amyloid cardiomyopathy (ATTR-CM) and polyneuropathy (ATTR-PN) amyloidosis: results of two focus groups.
Patient-reported burden of hereditary transthyretin amyloidosis on functioning and well-being.
Patisiran for advanced heart failure with hereditary transthyretin cardiac amyloidosis.
Patisiran for the treatment of hereditary transthyretin-mediated amyloidosis.
Patisiran Pharmacokinetics, Pharmacodynamics, and Exposure-Response Analyses in the Phase 3 APOLLO Trial in Patients With Hereditary Transthyretin-Mediated (hATTR) Amyloidosis.
Patisiran, an RNAi therapeutic for the treatment of hereditary transthyretin-mediated amyloidosis.
Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.
Pattern of myocardial 99mTc-HMDP uptake and impact on myocardial function in patients with transthyretin cardiac amyloidosis.
Pearls & Oy-sters: Number, Weaker, and Dizzier Due to Transthyretin Amyloidosis After 2 Liver Transplants.
Periorbital ecchymosis and shoulder pad sign in transthyretin amyloidosis.
Peripheral Blood Cell Gene Expression Diagnostic for Identifying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures.
Peripheral nerve ultrasonography in patients with transthyretin amyloidosis.
Peripheral neuropathy symptoms in wild type transthyretin amyloidosis.
Persistent Troponin Elevation in a Patient with Cardiac Amyloidosis.
Personalized medicine approach for optimizing the dose of tafamidis to potentially ameliorate wild-type transthyretin amyloidosis (cardiomyopathy).
Pharmacokinetics of Patisiran, the First Approved RNA Interference Therapy in Patients With Hereditary Transthyretin-Mediated Amyloidosis.
Pharmacokinetics of Tafamidis, a Transthyretin Amyloidosis Drug, in Rats.
Pharmacological Stimulation of Phagocytosis Enhances Amyloid Plaque Clearance; Evidence from a Transgenic Mouse Model of ATTR Neuropathy.
Pharmacotherapy review: Emerging treatment modalities in transthyretin cardiac amyloidosis.
Phase 3 Multicenter Study of Revusiran in Patients with Hereditary Transthyretin-Mediated (hATTR) Amyloidosis with Cardiomyopathy (ENDEAVOUR).
Phenome-wide association study of TTR and RBP4 genes in 361,194 individuals reveals novel insights in the genetics of hereditary and wildtype transthyretin amyloidoses.
Phenotypes of Late-Onset Transthyretin Amyloid Neuropathy: A Diagnostic Challenge.
Phenotypic characterization of late onset cardiac amyloidosis caused by the transthyretin mutation TTRA45S, p.(Ala65Ser).
Phenotypic Differences of Glu89Gln Genotype in ATTR Amyloidosis From Endemic Loci: Update From THAOS.
Phenotypic expression of familial amyloid polyneuropathy in Brazil.
Phenotypic expressions of hereditary Transthyretin Ala97Ser related Amyloidosis (ATTR) in Taiwanese.
Phenotypic profile of Ile68Leu transthyretin amyloidosis: an underdiagnosed cause of heart failure.
Physiological IgM class catalytic antibodies selective for transthyretin amyloid.
Pieter Cullis' quest for a lipid-based, fusogenic delivery system for nucleic acid therapeutics: success with siRNA so what about mRNA?
Pilot Study of F18-Florbetapir in the Early Evaluation of Cardiac Amyloidosis.
Plasma growth differentiation factor 15: a novel tool to detect early changes of hereditary transthyretin amyloidosis.
Plasma Hepatocyte Growth Factor for Diagnosis and Prognosis in Light Chain and Transthyretin Cardiac Amyloidosis.
Plasma hepatocyte growth factor is a novel marker of AL cardiac amyloidosis.
Plasma neurofilament light chain concentration is increased and correlates with the severity of neuropathy in hereditary transthyretin amyloidosis.
Plasma neurofilament light chain: an early biomarker for hereditary ATTR amyloid polyneuropathy.
Pompe Disease Could Mimic Exam Findings of Amyloidosis: Two Rare Diagnoses Bona Fide.
Population diversity of the genetically determined TTR expression in human tissues and its implications in TTR amyloidosis.
Population pharmacokinetic modelling and simulation of tafamidis in healthy subjects and patients with transthyretin amyloidosis.
Population Pharmacokinetic-Pharmacodynamic Model of Serum Transthyretin Following Patisiran Administration.
Population Pharmacokinetic-Pharmacodynamic Modeling of Inotersen, an Antisense Oligonucleotide for Treatment of Patients with Hereditary Transthyretin Amyloidosis.
Positive Effectiveness of Tafamidis in Delaying Disease Progression in Transthyretin Familial Amyloid Polyneuropathy up to 2 Years: An Analysis from the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Positron emission tomography (PET) utilizing Pittsburgh compound B (PIB) for detection of amyloid heart deposits in hereditary transthyretin amyloidosis (ATTR).
Potential Cardiac Amyloid PET/CT Imaging Targets for Differentiating Immunoglobulin Light Chain From Transthyretin Amyloidosis.
Potential treatment of transthyretin-type amyloidoses by sulfite.
Practical recommendations for the diagnosis and management of transthyretin cardiac amyloidosis.
Preclinical evaluation of RNAi as a treatment for transthyretin-mediated amyloidosis.
Prediction of long-term survival after liver transplantation for familial transthyretin amyloidosis.
Prediction of Medium-Term Mortality in Japanese Patients With Wild-Type Transthyretin Amyloidosis.
Predictive model of response to tafamidis in hereditary ATTR polyneuropathy.
Predictors of survival stratification in patients with wild-type cardiac amyloidosis.
Prenatal diagnosis of hereditary amyloidosis in a Portuguese family living in France.
Presence of val30Met and val122ile mutations in a patient with hereditary amyloidosis.
Pressure-Volume Relationships in Patients With Transthyretin (ATTR) Cardiac Amyloidosis Secondary to V122I Mutations and Wild-Type Transthyretin: Transthyretin Cardiac Amyloid Study (TRACS).
Prevalence and origin of amyloid in kidney biopsies.
Prevalence and Outcomes of p.Val142Ile TTR Amyloidosis Cardiomyopathy: A Systematic Review.
Prevalence and Prognostic Significance of Frailty Among Patients With Transthyretin Amyloidosis Cardiomyopathy.
Prevalence and prognostic value of autonomic neuropathy assessed by Sudoscan® in transthyretin wild-type cardiac amyloidosis.
Prevalence of cardiac amyloidosis among elderly patients with systolic heart failure or conduction disorders.
Prevalence of hereditary transthyretin amyloid polyneuropathy in idiopathic progressive neuropathy in conurban areas.
Prevalence of Monoclonal Gammopathy in Wild-Type Transthyretin Amyloidosis.
Prevalence of Positive 99 mTc-DPD Scintigraphy as an Indicator of the Prevalence of Wild-type Transthyretin Amyloidosis in the Elderly.
Prevalence of the amyloidogenic transthyretin (TTR) V122I allele in 14?333 African-Americans.
Prevalence of transthyretin amyloid cardiomyopathy in male patients who underwent bilateral carpal tunnel surgery: The ACTUAL study.
Prevalence of transthyretin amyloidosis in patients with heart failure and no left ventricular hypertrophy.
Prevalence of wild type ATTR assessed as myocardial uptake in bone scan in the elderly population.
Prevalence of wild type transtyrethin cardiac amyloidosis in a heart failure clinic.
Prevalence, Incidence, and Impact on Mortality of Conduction System Disease in Transthyretin Cardiac Amyloidosis.
Prevention of transthyretin amyloid disease by changing protein misfolding energetics.
Primary prevention implantable cardioverter-defibrillators in transthyretin cardiac amyloidosis.
Probing conformational changes of monomeric transthyretin with second derivative fluorescence.
Probing solvent accessibility of transthyretin amyloid by solution NMR spectroscopy.
Production and functional analysis of normal and variant recombinant human transthyretin proteins.
Prognostic impact of light-chain and transthyretin-related categories in cardiac amyloidosis: a systematic review and meta-analysis.
Prognostic implication of relative regional strain ratio in cardiac amyloidosis.
Prognostic Role of Cardiopulmonary Exercise Testing in Wild-Type Transthyretin Amyloid Cardiomyopathy Patients Treated With Tafamidis.
Prognostic significance of incidental suspected transthyretin amyloidosis on routine bone scintigraphy.
Prognostic Significance of Occult Transthyretin Cardiac Amyloidosis in Patients With Severe Aortic Stenosis Undergoing Surgical Aortic Valve Replacement: An Unrecognized Disease Modifier.
Prognostic Utility of Echocardiographic Atrial and Ventricular Strain Imaging in Patients With Cardiac Amyloidosis.
Prognostic utility of the Perugini grading of 99mTc-DPD scintigraphy in transthyretin (ATTR) amyloidosis and its relationship with skeletal muscle and soft tissue amyloid.
Prognostic Value of Late Gadolinium Enhancement Cardiovascular Magnetic Resonance in Cardiac Amyloidosis.
Progress and challenges in the treatment of cardiac amyloidosis: a review of the literature.
Progression of cardiac amyloid deposition in hereditary transthyretin amyloidosis patients after liver transplantation.
Progression of cardiomyopathy after liver transplantation in patients with familial amyloidotic polyneuropathy, Portuguese type.
Progression of cardiomyopathy and neuropathy after liver transplantation in a patient with familial amyloidotic polyneuropathy caused by tyrosine-77 transthyretin variant.
Progression of transthyretin (TTR) amyloidosis in donors and recipients after domino liver transplantation-a prospective single-center cohort study.
Progression of transthyretin amyloid neuropathy after liver transplantation.
Progressive brachial plexus enlargement in hereditary transthyretin amyloidosis.
Progressive deterioration of frailty is associated with poor outcomes in patients with transthyretin cardiac amyloidosis.
Proportion between wild-type and mutant protein in truncated compared to full-length ATTR: an analysis on transplanted transthyretin T60A amyloidosis patients.
Proposing a minimal set of metrics and methods to predict probabilities of amyloidosis disease and onset age in individuals.
Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: The Transthyretin Amyloidosis Cardiac Study (TRACS).
Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis.
Proteome analysis of cerebrospinal fluid in Guillain-Barré syndrome (GBS).
Proteomic analysis of inclusion body myositis.
Proteomic characterization of amyloid deposits in transthyretin amyloidosis associated with various mutations.
Psychosocial burden and professional and social support in patients with hereditary transthyretin amyloidosis (ATTRv) and their relatives in Italy.
Pupillometry: An objective test to assess endocular hereditary transthyretin amyloidosis.
Purification of transthyretin and transthyretin fragments from amyloid-rich human tissues.
Q-Rich Yeast Prion [
Quadriceps tendon rupture in wild-type transthyretin amyloidosis (ATTRwt).
Quality of life assessment in amyloid transthyretin (ATTR) amyloidosis.
Quantification of cardiac amyloid with [18F]Flutemetamol in patients with V30M hereditary transthyretin amyloidosis.
Quantification of myocardial 99mTc-labeled bisphosphonate uptake with cadmium zinc telluride camera in patients with transthyretin-related cardiac amyloidosis.
Quantification of the thermodynamically linked quaternary and tertiary structural stabilities of transthyretin and its disease-associated variants: the relationship between stability and amyloidosis.
Quantification of transthyretin kinetic stability in human plasma using subunit exchange.
Quantitation of 99mTc-DPD uptake in patients with transthyretin-related cardiac amyloidosis.
Quantitative sensation and autonomic test abnormalities in transthyretin amyloidosis polyneuropathy.
Quantitative SPECT/CT parameters of myocardial 99mTechnetium-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) uptake in suspected cardiac transthyretin amyloidosis.
Quaternary structure, aggregation and cytotoxicity of transthyretin.
Radionuclide Imaging in the Diagnosis of Transthyretin Cardiac Amyloidosis: Different Sensitivity in Early-Onset V30M Mutation?
Radionuclide Imaging of Cardiac Amyloidosis and Sarcoidosis: Roles and Characteristics of Various Tracers.
Rapid decline in ejection fraction and persistent elevation of troponin associated with cardiac amyloidosis.
Rapid detection of wild-type and mutated transthyretins.
Rapid method to characterize mutations in transthyretin in cerebrospinal fluid from familial amyloidotic polyneuropathy patients by use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Rapidly Progressive Transthyretin-Mediated Amyloidosis in a Domino Liver Transplant Recipient of a Ser23Asn Donor.
Rare variant (p.Ser43Asn) of familial transthyretin amyloidosis associated with isolated cardiac phenotype: A case series with literature review.
Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis.
Rate of progression of transthyretin amyloidosis.
Rational design of potent human transthyretin amyloid disease inhibitors.
Rationale for a Singapore Transthyretin Amyloidosis Registry.
Real-world outcomes in non-endemic hereditary transthyretin amyloidosis with polyneuropathy: a 20-year German single-referral centre experience.
Recent Advances and Current Dilemmas in the Diagnosis and Management of Transthyretin Cardiac Amyloidosis.
Recent Advances in Oligonucleotide-Based Therapy for Transthyretin Amyloidosis: Clinical Impact and Future Prospects.
Recent advances in the diagnosis and management of amyloid cardiomyopathy.
Recent advances in the diagnosis and management of cardiac amyloidosis.
Recent advances in the noninvasive strategies of cardiac amyloidosis.
Recent advances in transthyretin amyloidosis therapy.
Recent progress in the understanding and treatment of transthyretin amyloidosis.
Recipient Aging Accelerates Acquired Transthyretin Amyloidosis After Domino Liver Transplantation.
Recognizing Transthyretin Cardiac Amyloidosis in Patients With Aortic Stenosis: Impact on Prognosis.
Recommendations for pre-symptomatic genetic testing for hereditary transthyretin amyloidosis in the era of effective therapy: a multicenter Italian consensus.
Recommendations for presymptomatic genetic testing and management of individuals at risk for hereditary transthyretin amyloidosis.
Recommendations for the diagnosis and management of transthyretin amyloidosis with gastrointestinal manifestations.
Recurrent subarachnoid hemorrhage associated with a new transthyretin variant (Gly53Glu).
Red flags in patients with hereditary transthyretin amyloidosis at diagnosis in a non-endemic area of Spain.
Reduced intraepidermal nerve fibre density in patients with hereditary transthyretin amyloidosis.
Reduced left atrial myocardial deformation irrespective of cavity size: a potential cause for atrial arrhythmia in hereditary transthyretin amyloidosis.
Reduced myocardial 123-iodine metaiodobenzylguanidine uptake: a prognostic marker in familial amyloid polyneuropathy.
Reduced trans-mitral A-wave velocity predicts the presence of wild-type transthyretin amyloidosis in elderly patients with left ventricular hypertrophy.
Reduction of free radical activity in amyloid deposits following liver transplantation for familial amyloidotic polyneuropathy.
Refractory Heart Failure of Unknown Etiology May Be Cardiac Amyloid If Preceded by Hereditary Neurological Symptoms.
Regional Variation in Technetium Pyrophosphate Uptake in Transthyretin Cardiac Amyloidosis and Impact on Mortality.
Regression of Bone-Tracer Uptake in Cardiac Transthyretin Amyloidosis.
Relation of clinical, echocardiographic and electrocardiographic features of cardiac amyloidosis to the presence of the transthyretin V122I allele in older African-American men.
Relationship between amyloid deposition and intracellular structural changes in familial amyloidotic polyneuropathy.
Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue.
Renal Infarction and Its Consequences for Renal Function in Patients With Cardiac Amyloidosis.
Renal Involvement in Hereditary Transthyretin Amyloidosis: An Italian Single-Centre Experience.
Reply: Liver transplantation in transthyretin amyloidosis: Issues and challenges.
Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity.
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
Responder analysis for neuropathic impairment and quality-of-life assessment in patients with hereditary transthyretin amyloidosis with polyneuropathy in the NEURO-TTR study.
Response: Atrial impairment in transthyretin cardiac amyloidosis: an early marker of cardiac involvement and a prognostic factor.
Restriction fragment length polymorphism analysis of mutated transthyretin in vitreous amyloidosis.
Restrictive cardiomyopathy in inherited ATTR amyloidosis (TTR-Ser23Asn) in a patient of German-Italian extraction.
Results of liver transplantation for familial amyloid polyneuropathy type I in Brazil.
Retinol binding protein 4 (RBP4) concentration identifies V122I transthyretin cardiac amyloidosis.
Reversible myocardial oedema due to acute myocardial infarction as differential diagnosis of cardiac transthyretin amyloidosis.
Review of Transthyretin Silencers, Stabilizers, and Fibril Removal Agents in the Treatment of Transthyretin Cardiac Amyloid.
Review: TTR amyloidosis-structural features leading to protein aggregation and their implications on therapeutic strategies.
Revised transthyretin Ile 122 allele frequency in African-Americans.
Revisiting transthyretin related cardiac amyloidosis: Case report and review of literature.
Rhabdomyolysis in the Setting of Concomitant Use of Tafamidis, Atorvastatin, and Amiodarone.
Right ventricular involvement in transthyretin amyloidosis.
Risk of transmission of systemic transthyretin amyloidosis after domino liver transplantation.
Role of natriuretic peptide to predict cardiac abnormalities in patients with hereditary transthyretin amyloidosis.
Role of Right Ventricular Strain Measured by Two-Dimensional Echocardiography in the Diagnosis of Cardiac Amyloidosis.
Role of serum amyloid P component for systemic amyloidosis in transgenic mice carrying human mutant transthyretin gene.
Role of the glutamic acid 54 residue in transthyretin stability and thyroxine binding.
Ruptured Bullae: A Case of Transthyretin Cardiac Amyloidosis.
S-sulfonation of transthyretin is an important trigger step in the formation of transthyretin-related amyloid fibril.
Safety and efficacy of a TTR specific antisense oligonucleotide in patients with transthyretin amyloid cardiomyopathy.
Safety and efficacy of long-term diflunisal administration in hereditary transthyretin (ATTR) amyloidosis.
Safety and efficacy of RNAi therapy for transthyretin amyloidosis.
Scavenger treatment of free radical injury in familial amyloidotic polyneuropathy: a study on Swedish transplanted and non-transplanted patients.
Schwann cells contribute to neurodegeneration in transthyretin amyloidosis.
Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review.
Scintigraphic images of transthyretin cardiac amyloidosis progression.
Screening for ATTR amyloidosis in the clinic: overlapping disorders, misdiagnosis, and multiorgan awareness.
Screening for genetic mutations in patients with neuropathy without definite etiology is useful.
Screening for hereditary transthyretin amyloidosis in Bulgaria.
Seeking confidence in the diagnosis of systemic AL (Ig light-chain) amyloidosis: patients can have both monoclonal gammopathies and hereditary amyloid proteins.
Selection of hereditary transthyretin amyloid patients for liver transplantation: the Swedish experience.
Selective silencing of a mutant transthyretin allele by small interfering RNAs.
Self-reported gastrointestinal symptoms are more common in liver transplanted transthyretin amyloidosis patients than in healthy controls and in patients transplanted for end-stage liver disease.
Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Senile cardiac amyloidosis associated with homozygosity for a transthyretin variant (ILE-122).
Senile cardiac amyloidosis: an underappreciated cause of heart failure.
Senile systemic amyloidosis affects 25% of the very aged and associates with genetic variation in alpha2-macroglobulin and tau: a population-based autopsy study.
Senile Systemic Amyloidosis Presenting as Hematuria: A Rare Presentation and Review of Literature.
Senile Systemic Amyloidosis: An Underdiagnosed Disease.
Senile systemic amyloidosis: clinical features at presentation and outcome.
Senile transthyretin cardiac amyloidosis in patients with plasma cell dyscrasias: importance of cardiac biopsy for making the correct diagnosis.
Serial scanning with technetium pyrophosphate ((99m)Tc-PYP) in advanced ATTR cardiac amyloidosis.
SERPINA1 modulates expression of amyloidogenic transthyretin.
Serum levels of NT-proBNP as surrogate for cardiac amyloid burden: new evidence from gadolinium-enhanced cardiac magnetic resonance imaging in patients with amyloidosis.
Serum Proteomic Variability Associated with Clinical Phenotype in Familial Transthyretin Amyloidosis (ATTRm).
Serum transthyretin levels in senile systemic amyloidosis: effects of age, gender and ethnicity.
Serum transthyretin monomer in patients with familial amyloid polyneuropathy.
Serum Transthyretin: Predictor of Amyloidosis Outcomes?
Seven factors predict a delayed diagnosis of cardiac amyloidosis.
Severe Aortic Stenosis and ATTRwt Amyloidosis - Beware in the Aging: A Case Report and Review of the Literature.
Severe hand pain as an extracardiac manifestation of transthyretin amyloidosis.
Severe heart disease in an unusual case of familial amyloid polyneuropathy type I.
Sex Differences in the Phenotype of Transthyretin Cardiac Amyloidosis Due to Val122Ile Mutation: Insights from Noninvasive Pressure-Volume Analysis.
Sex-Related Risk of Cardiac Involvement in Hereditary Transthyretin Amyloidosis: Insights From THAOS.
Single AAV-mediated CRISPR-Nme2Cas9 efficiently reduces mutant hTTR expression in a transgenic mouse model of transthyretin amyloidosis.
Single-centre experience of liver transplantation for familial amyloidotic polyneuropathy of non-Val30Met variants in Chinese patients.
Single-Dose Pharmacokinetics and Pharmacodynamics of Transthyretin Targeting N-acetylgalactosamine-Small Interfering Ribonucleic Acid Conjugate, Vutrisiran, in Healthy Subjects.
Small fiber neuropathy in Sjögren syndrome: Comparison with other small fiber neuropathies.
Small fiber neuropathy: Diagnosis, causes, and treatment.
Small gauge vitrectomy for vitreous amyloidosis and subsequent management of secondary glaucoma in patients with hereditary transthyretin amyloidosis.
Small interfering RNA from the lab discovery to patients' recovery.
Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses.
Small-Molecule Screening for Genetic Diseases.
Societal costs and burden of hereditary transthyretin amyloidosis polyneuropathy.
Solar Eruption in Hereditary Transthyretin Amyloidosis.
Solid Organ Transplantation in Amyloidosis.
Specific Disruption of Transthyretin(105-115) Fibrilization Using "Stabilizing" Inhibitors of Transthyretin Amyloidogenesis.
Specific pathogen free conditions prevent transthyretin amyloidosis in mouse models.
Specific postoperative complications of vitrectomy in hereditary transthyretin amyloidosis.
Specific Therapy for Transthyretin Cardiac Amyloidosis: A Systematic Literature Review and Evidence-Based Recommendations.
Speckle tracking echo to assess transthyretin amyloidosis type: is it useful (or necessary)?
Spectrum of Restrictive and Infiltrative Cardiomyopathies: Part 1 of a 2-Part Series.
Spectrum of transthyretin gene mutations and clinical characteristics of Polish patients with cardiac transthyretin amyloidosis.
Spinal multifocal amyloidosis derived from wild-type transthyretin.
Spinal Stenosis in Familial Transthyretin Amyloidosis.
Splenic regression of amyloid on multi-modality imaging in response to treatment with patisiran and diflunisal in hereditary transthyretin amyloidosis.
Spontaneous intramyocardial haemorrhage in a patient with wild-type transthyretin cardiac amyloidosis.
Sporadic Cardiac Amyloidosis by Amyloidogenic Transthyretin V122I Variant.
Sporadic transthyretin amyloidosis with a novel TTR gene mutation misdiagnosed as primary amyloidosis.
Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis.
Standard heart failure medication in cardiac transthyretin amyloidosis: useful or harmful?
Standardization of (99m)Technetium pyrophosphate imaging methodology to diagnose TTR cardiac amyloidosis.
State-of-the-art radionuclide imaging in cardiac transthyretin amyloidosis.
Strange case of biventricular heart failure.
Strategies to improve the quality of life in patients with hereditary transthyretin amyloidosis (hATTR) and autonomic neuropathy.
Stroke risk and atrial mechanical dysfunction in cardiac amyloidosis.
Strong transthyretin immunostaining: potential pitfall in cardiac amyloid typing.
Structural evidence for asymmetric ligand binding to transthyretin.
Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils.
Structural Stabilization of Human Transthyretin by Centella asiatica (L.) Urban Extract: Implications for TTR Amyloidosis.
Structure of Met30 variant of transthyretin and its amyloidogenic implications.
Structure of Monomeric Transthyretin Carrying the Clinically Important T119M Mutation.
Structure-activity relationships of flurbiprofen analogues as stabilizers of the amyloidogenic protein transthyretin.
Structure-based design of kinetic stabilizers that ameliorate the transthyretin amyloidoses.
Studies on plasma transthyretin (prealbumin) in familial amyloidotic polyneuropathy, Portuguese type.
Subclinical retinal angiopathy associated with hereditary transthyretin amyloidosis - assessed with optical coherence tomography angiography.
Substoichiometric inhibition of transthyretin misfolding by immune-targeting sparsely populated misfolding intermediates: a potential diagnostic and therapeutic for TTR amyloidoses.
Subthreshold Aortic Valve Calcium Scores in Severe Aortic Stenosis and Transthyretin Cardiac Amyloidosis.
Subtype-Specific Interactions and Prognosis in Cardiac Amyloidosis.
Successful Heart and Liver Transplantation in a Swiss Patient With Glu89Lys Transthyretin Amyloidosis.
Supercentenarians and transthyretin amyloidosis: the next frontier of human life extension.
Support for the multigenic hypothesis of amyloidosis: the binding stoichiometry of retinol-binding protein, vitamin A, and thyroid hormone influences transthyretin amyloidogenicity in vitro.
Supporting the Assessment of Hereditary Transthyretin Amyloidosis Patients Based On 3-D Gait Analysis and Machine Learning.
Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides.
Suppression of choroid plexus transthyretin levels by antisense oligonucleotide treatment.
Survival After Transplantation in Patients With Mutations Other Than Val30Met: Extracts From the FAP World Transplant Registry.
Sustained Ventricular Tachycardia as a Harbinger of Cardiac Amyloidosis.
Symptomatic Val122del mutated hereditary transthyretin amyloidosis: Need for early diagnosis and prioritization for heart and liver transplantation.
Syncope as a Phenotypic Expression of Hereditary Transthyretin Amyloidosis Val142Ile (Val122Ile).
Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
Synthesis and evaluation of transthyretin amyloidosis inhibitors containing carborane pharmacophores.
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
Synthesis of an analog of the thyroid hormone-binding protein transthyretin via regioselective chemical ligation.
Systemic amyloidosis in laying Japanese quail.
Systemic amyloidosis in transgenic mice carrying the human mutant transthyretin (Met 30) gene. Pathological and immunohistochemical similarity to human familial amyloidotic polyneuropathy, type I.
Systemic amyloidosis in transgenic mice carrying the human mutant transthyretin (Met30) gene. Pathologic similarity to human familial amyloidotic polyneuropathy, type I.
Systemic Amyloidosis Recognition, Prognosis, and Therapy: A Systematic Review.
Systemic amyloidosis.
Systemic angiopathy and axonopathy in hereditary transthyretin amyloidosis with Ala97Gly (p. Ala117Gly) mutation: a post-mortem analysis.
Systemic but asymptomatic transthyretin amyloidosis 8 years after domino liver transplantation.
Systemic transthyretin amyloidosis in a patient with bent spine syndrome.
Tafamidis for autonomic neuropathy in hereditary transthyretin (ATTR) amyloidosis: a review.
Tafamidis for the Treatment of Hereditary Transthyretin Amyloid Cardiomyopathy: A Case Report.
Tafamidis for the treatment of transthyretin amyloidosis.
Tafamidis for transthyretin amyloidosis.
Tafamidis in transthyretin amyloid cardiomyopathy: effects on transthyretin stabilization and clinical outcomes.
Tafamidis, a Noninvasive Therapy for Delaying Transthyretin Familial Amyloid Polyneuropathy: Systematic Review and Meta-Analysis.
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
Tafamidis.
Tafamidis: A Review in Transthyretin Amyloidosis with Polyneuropathy.
Tafamidis: a review of its use in familial amyloid polyneuropathy.
Tafamidis: a selective transthyretin stabilizer to treat wild-type ATTR amyloidosis and hereditary ATTR amyloidosis with cardiomyopathy.
Targeted Nuclear Imaging Probes for Cardiac Amyloidosis.
Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides.
Targeted Therapeutics for Transthyretin Cardiac Amyloidosis.
Targeting a rare amyloidotic disease through rationally designed polymer conjugates.
Targeting Different Transthyretin Binding Sites with Unusual Natural Compounds.
Targeting transthyretin - Mechanism-based treatment approaches and future perspectives in hereditary amyloidosis.
Targeting transthyretin amyloidosis in the eye with next-generation stabilizers: AT40 displays potent TTR stabilization in the human vitreous.
Tc-99m pyrophosphate imaging for transthyretin cardiac amyloidosis: Importance of estimation of cancer risk with the modality.
Teaching NeuroImages: Morphology of lumbosacral dorsal root ganglia and plexus in hereditary transthyretin amyloidosis.
Teaching NeuroImages: Neuromyopathy in a patient with hereditary transthyretin Thr60Ala amyloidosis.
Technetium 99m pyrophosphate radioisotope for diagnosis and prognosis of transthyretin cardiac amyloidosis: A call for collaboration.
Technetium pyrophosphate myocardial uptake and peripheral neuropathy in a rare variant of familial transthyretin (TTR) amyloidosis (Ser23Asn): a case report and literature review.
Technetium pyrophosphate uptake in transthyretin cardiac amyloidosis: Associations with echocardiographic disease severity and outcomes.
Tegsedi (Inotersen): An Antisense Oligonucleotide Approved for the Treatment of Adult Patients with Hereditary Transthyretin Amyloidosis.
Temporal Change in Longitudinal Strain After Domino Liver Transplantation With Liver Grafts Explanted From Patients With Hereditary Amyloidogenic Transthyretin Amyloidosis.
Ten years of international experience with liver transplantation for familial amyloidotic polyneuropathy: results from the Familial Amyloidotic Polyneuropathy World Transplant Registry.
Tenosynovial and Cardiac Transthyretin Amyloidosis in Japanese Patients Undergoing Carpal Tunnel Release.
Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation.
Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer.
Tetraparesis and sensorimotor axonal polyneuropathy due to co-occurrence of Pompe disease and hereditary ATTR amyloidosis.
THAOS - The Transthyretin Amyloidosis Outcomes Survey: initial report on clinical manifestations in patients with hereditary and wild-type transthyretin amyloidosis.
THAOS: gastrointestinal manifestations of transthyretin amyloidosis - common complications of a rare disease.
The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity.
The beta-slip: a novel concept in transthyretin amyloidosis.
The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin.
The Bioequivalence of Tafamidis 61-mg Free Acid Capsules and Tafamidis Meglumine 4 × 20-mg Capsules in Healthy Volunteers.
The challenging histological diagnosis of transthyretin (ATTR) amyloidosis.
The Clinical and Economic Burden of Newly Diagnosed Hereditary Transthyretin (ATTRv) Amyloidosis: A Retrospective Analysis of Claims Data.
The Clinical Implication of Incidental Prostatic Amyloidosis.
The crystal structure of transthyretin from chicken.
The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors.
The current status of quantitative SPECT/CT in the assessment of transthyretin cardiac amyloidosis.
The current status of the Transthyretin Amyloidosis Outcomes Survey (THAOS) in Japan.
The demographic, genetic, and clinical characteristics of Brazilian subjects enrolled in the Transthyretin Amyloidosis Outcomes Survey.
The demographic, genetic, and clinical characteristics of Latin American subjects enrolled in the Transthyretin Amyloidosis Outcomes Survey.
The diagnostic challenges of cardiac amyloidosis: A practical approach to the two main types.
The Effectiveness and Value of Patisiran and Inotersen for Hereditary Transthyretin Amyloidosis.
The electrocardiographic features associated with cardiac amyloidosis of variant transthyretin isoleucine 122 type in Afro-Caribbean patients.
The ever-growing understanding of transthyretin amyloidosis nephropathy.
The Evolving Role of Cardiovascular Magnetic Resonance Imaging in the Evaluation of Systemic Amyloidosis.
The Expression of Chemokines Is Downregulated in a Pre-Clinical Model of TTR V30M Amyloidosis.
The first Caucasian patient with p.Val122Ile mutated-transthyretin cardiac amyloidosis treated with isolated heart transplantation.
The flavonoid luteolin, but not luteolin-7-O-glucoside, prevents a transthyretin mediated toxic response.
The frequency of central nervous system complications in the Cypriot cohort of ATTRV30M neuropathy transplanted patients.
The genetic heterogeneity of hereditary transthyretin amyloidosis in a sample of the Brazilian population.
The identification of a transthyretin variant p.D38G in a Chinese family with early-onset leptomeningeal amyloidosis.
The impact of clinical heterogeneity on conducting network meta-analyses in transthyretin amyloidosis with polyneuropathy.
The importance of a gatekeeper residue on the aggregation of transthyretin: implications for transthyretin-related amyloidoses.
The liver in systemic amyloidosis: insights from 123I serum amyloid P component scintigraphy in 484 patients.
The molecular biology and clinical features of amyloid neuropathy.
The morphology of amyloid fibrils and their impact on tissue damage in hereditary transthyretin amyloidosis: An ultrastructural study.
The myocardial contraction fraction is superior to ejection fraction in predicting survival in patients with AL cardiac amyloidosis.
The neuropathy in hereditary transthyretin amyloidosis: A narrative review.
The pathologic spectrum of oculoleptomeningeal amyloidosis with Val30Gly transthyretin gene mutation in a postmortem case.
The pathological and biochemical identification of possible seed-lesions of transmitted transthyretin amyloidosis after domino liver transplantation.
The patient journey toward a diagnosis of hereditary transthyretin (ATTRv) amyloidosis.
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies.
The premortem recognition of systemic senile amyloidosis with cardiac involvement.
The prevalence and distribution of the amyloidogenic transthyretin (TTR) V122I allele in Africa.
The Prevalence and Management of Systemic Amyloidosis in Western Countries.
The Prevalence of Advanced Interatrial Block and Its Relationship to Left Atrial Function in Patients with Transthyretin Cardiac Amyloidosis.
The prevalence of TTR cardiac amyloidosis among patients undergoing bone scintigraphy.
The prostate as a good candidate organ for proving amyloid deposition in non-endemic late onset hereditary transthyretin amyloidosis: Report of two cases.
The proteome response to amyloid protein expression in vivo.
The quintessential form of diastolic heart failure in older adults: Wild type transthyretin cardiac amyloidosis.
The relative amounts of plasma transthyretin forms in familial transthyretin amyloidosis: a quantitative analysis by Fourier transform ion-cyclotron resonance mass spectrometry.
The role of fibrinogen glycation in ATTR: evidence for chaperone activity loss in disease.
The Role of Imaging in Diagnosing Transthyretin Cardiac Amyloidosis.
The Role of Multi-modality Imaging in the Diagnosis of Cardiac Amyloidosis: A Focused Update.
The sensitivity of DPD scintigraphy to detect transthyretin cardiac amyloidosis in V30M mutation depends on the phenotypic expression of the disease.
The Structural Understanding of Transthyretin Misfolding and the Inspired Drug Approaches for the Treatment of Heart Failure Associated With Transthyretin Amyloidosis.
The Swedish open-label diflunisal trial (DFNS01) on hereditary transthyretin amyloidosis and the impact of amyloid fibril composition.
The systemic amyloidoses.
The Tenosynovitis of Fingers Associated with Transthyretin Amyloidosis.
The transmissible amyloidoses: genetical control of spontaneous generation of infectious amyloid proteins by nucleation of configurational change in host precursors: kuru-CJD-GSS-scrapie-BSE.
The transthyretin amyloidoses: advances in therapy.
The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug.
The Transthyretin Amyloidosis Outcomes Survey (THAOS) registry: design and methodology.
The transthyretin cDNA sequence is normal in transthyretin-derived senile systemic amyloidosis.
The Truth Is Unfolding About Transthyretin Cardiac Amyloidosis.
The Ultrastructure of Tissue Damage by Amyloid Fibrils.
The use of diflunisal for transthyretin cardiac amyloidosis: a review.
The use of subcutaneous fat tissue for amyloid typing by enzyme-linked immunosorbent assay.
The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.
The Val142Ile transthyretin cardiac amyloidosis: more than an Afro-American pathogenic variant.
The Val142Ile transthyretin cardiac amyloidosis: not only an Afro-American pathogenic variant? A single-centre Italian experience.
The Value of Nerve Biopsy in Transthyretin Amyloidosis with Competing Comorbidities.
The value of screening biopsies in light-chain (AL) and transthyretin (ATTR) amyloidosis.
Therapeutic Potential of Polyamidoamine Dendrimer for Amyloidogenic Transthyretin Amyloidosis.
Thermodynamic Stability and Aggregation Kinetics of EF Helix and EF Loop Variants of Transthyretin.
Thyroxine binding to transthyretin Met 119. Comparative studies of different heterozygotic carriers and structural analysis.
Time Course of Common Clinical Manifestations in Patients with Transthyretin Cardiac Amyloidosis: Delay From Symptom Onset to Diagnosis.
Time Domain Optical Coherence Tomography in Familial Vitreous Amyloidosis Associated Transthyretin Met30 Mutation.
Tissue damage in the amyloidoses: Transthyretin monomers and nonnative oligomers are the major cytotoxic species in tissue culture.
Tolcapone, a potent aggregation inhibitor for the treatment of familial leptomeningeal amyloidosis.
Top-Down Analysis of Small Plasma Proteins Using an LTQ-Orbitrap. Potential for Mass Spectrometry-Based Clinical Assays for Transthyretin and Hemoglobin.
Tracheobronchial Amyloidosis in a Patient with Sjögren's Syndrome.
Trajectory of left ventricular geometry and diastolic dysfunction in hereditary transthyretin cardiac amyloidosis.
Transmission of systemic transthyretin amyloidosis by means of domino liver transplantation.
Transradial left ventricular endomyocardial biopsy feasibility, safety and clinical usefulness: Initial experience of a tertiary university center.
Transthyretin (ATTR) amyloidosis nephropathy: lessons from a TTR stabilizer molecule.
Transthyretin (ATTR) amyloidosis: clinical spectrum, molecular pathogenesis and disease-modifying treatments.
Transthyretin (TTR) Cardiac Amyloidosis.
Transthyretin Ala36Pro mutation in a Chinese pedigree of familial transthyretin amyloidosis with elevated vitreous and serum vascular endothelial growth factor.
Transthyretin Amyloid Cardiomyopathy-Current and Future Therapies.
Transthyretin amyloid cardiomyopathy.
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis.
Transthyretin Amyloid Fibril Disrupting Activities of Extracts and Fractions from Juglans mandshurica Maxim. var. cordiformis (Makino) Kitam.
Transthyretin amyloid fibrils alter primary fibroblast structure, function, and inflammatory gene expression.
Transthyretin Amyloid Goiter in a Renal Allograft Recipient.
Transthyretin amyloid neuropathy has earlier neural involvement but better prognosis than primary amyloid counterpart: an answer to the paradox?
Transthyretin Amyloid Neuropathy: The Schwann Cell Hypothesis.
Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of De Novo generation of Creutzfeldt-Jakob disease infectious amyloid by a spontaneous change in configuration of the host precursor protein.
Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of spontaneous generation of infectious amyloids by patterned configurational change in host precursors in Creutzfeldt-Jacob disease.
Transthyretin Amyloidosis (ATTR) - The Role of Multimodality in the Definitive Diagnosis.
Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy.
Transthyretin amyloidosis and herpes zoster infection: a mimic of temporal arteritis.
Transthyretin amyloidosis and superficial siderosis of the CNS.
Transthyretin amyloidosis and the kidney.
Transthyretin amyloidosis and two other aging-related amyloidoses in an aged vervet monkey.
Transthyretin amyloidosis associated with a novel variant (Trp41Leu) presenting with vitreous opacities.
Transthyretin amyloidosis in a patient of Iranian-Jewish extraction: a second Israeli-Jewish case.
Transthyretin amyloidosis in a septuagenarian masquerading as hypertrophic cardiomyopathy: the importance of multimodality imaging.
Transthyretin amyloidosis in patients with undifferentiated heart failure.
Transthyretin amyloidosis in Western Europe: a snapshot from the THAOS registry and a call for further perspectives.
Transthyretin Amyloidosis Mimicking Obstructive Hypertrophic Cardiomyopathy: A Great Imitator.
Transthyretin amyloidosis presenting with multifocal demyelinating mononeuropathies.
Transthyretin Amyloidosis Presenting With Upper-Extremity Neuropathy and Paucity of Autonomic Impairment.
Transthyretin amyloidosis with cardiomyopathy after domino liver transplantation: Results of a cross-sectional study.
Transthyretin Amyloidosis with Gastrointestinal Manifestation: a Case Report.
Transthyretin amyloidosis with pulmonary involvement in a patient with monoclonal gammapathy.
Transthyretin Amyloidosis: A "Zebra" of Many Stripes.
Transthyretin amyloidosis: A hidden diagnosis.
Transthyretin amyloidosis: a little history of hereditary amyloidosis.
Transthyretin amyloidosis: a new mutation associated with dementia.
Transthyretin amyloidosis: a phenocopy of hypertrophic cardiomyopathy.
Transthyretin amyloidosis: a tale of weak interactions.
Transthyretin amyloidosis: an under-recognized neuropathy and cardiomyopathy.
Transthyretin Amyloidosis: Chaperone Concentration Changes and Increased Proteolysis in the Pathway to Disease.
Transthyretin amyloidosis: new answers but many questions.
Transthyretin amyloidosis: Putting myopathy on the map.
Transthyretin amyloidosis: Testing strategies and model for center of excellence support.
Transthyretin Amyloidosis: Update on the Clinical Spectrum, Pathogenesis, and Disease-Modifying Therapies.
Transthyretin and amyloid in the islets of Langerhans in type-2 diabetes.
Transthyretin Anti-Amyloidogenic and Fibril Disrupting Activities of Bacopa monnieri (L.) Wettst (Brahmi) Extract.
Transthyretin Arg-83 mutation in vitreous amyloidosis.
Transthyretin Cardiac Amyloidoses in Older North Americans.
Transthyretin Cardiac Amyloidosis and Aortic Stenosis: Connection and Therapeutic Implications.
Transthyretin Cardiac Amyloidosis and Novel Therapies to Treat This Not-so-rare Cause of Cardiomyopathy.
Transthyretin Cardiac Amyloidosis as Diagnosed by 99mTc-PYP Scanning in Patients with Acute Heart Failure and Preserved Ejection Fraction.
Transthyretin cardiac amyloidosis diagnosed by analyzing a prostatic tissue sample: a case report.
Transthyretin Cardiac Amyloidosis Due to Homozygous Val122Ile Mutation in a Caucasian Man.
Transthyretin cardiac amyloidosis in aortic stenosis: Prevalence, diagnostic challenges, and clinical implications.
Transthyretin Cardiac Amyloidosis in Black Americans.
Transthyretin cardiac amyloidosis in continental Western Europe: an insight through the Transthyretin Amyloidosis Outcomes Survey (THAOS).
Transthyretin Cardiac Amyloidosis in Older Adults: Optimizing Cardiac Imaging to the Corresponding Diagnostic and Management Goal.
Transthyretin Cardiac Amyloidosis in Older Americans.
Transthyretin cardiac amyloidosis in patients with severe aortic stenosis.
Transthyretin Cardiac Amyloidosis in the Elderly-Tip of a Heart Failure Iceberg?
Transthyretin Cardiac Amyloidosis Scintigraphy Using Planar D-SPECT on Dedicated Cardiac CZT Camera.
Transthyretin Cardiac Amyloidosis.
Transthyretin cardiac amyloidosis.
Transthyretin Cardiac Amyloidosis: A Noninvasive Multimodality Approach to Diagnosis Using Transthoracic Echocardiography, 99m-Tc-Labeled Phosphate Bone Scanning, and Cardiac Magnetic Resonance Imaging.
Transthyretin cardiac amyloidosis: a review of the nuclear imaging findings with emphasis on the radiotracers mechanisms.
Transthyretin cardiac amyloidosis: A treatable form of heart failure with a preserved ejection fraction.
Transthyretin cardiac amyloidosis: an under-diagnosed cause of heart failure.
Transthyretin cardiac amyloidosis: an update on diagnosis and treatment.
Transthyretin Cardiac Amyloidosis: From Rare Monogenic Disease to Common Pathway in Heart Failure?
Transthyretin cardiac amyloidosis: pathogenesis, treatments, and emerging role in heart failure with preserved ejection fraction.
Transthyretin chemical chaperoning by flavonoids: Structure-activity insights towards the design of potent amyloidosis inhibitors.
Transthyretin deposition in familial amyloidotic polyneuropathy.
Transthyretin deposition in the eye in the era of effective therapy for hereditary ATTRV30M amyloidosis.
Transthyretin familial amyloid polyneuropathy (TTR-FAP): Parameters for early diagnosis.
Transthyretin forms amyloid fibrils at physiological pH with ultrasonication.
Transthyretin Ile 122 and cardiac amyloidosis in African-Americans. 2 case reports.
Transthyretin ILE20, a new variant associated with late-onset cardiac amyloidosis.
Transthyretin is up-regulated by sex hormones in mice liver.
Transthyretin Leu 68 in a form of cardiac amyloidosis.
Transthyretin Leu12Pro is associated with systemic, neuropathic and leptomeningeal amyloidosis.
Transthyretin Pro 36 associated with familial amyloidotic polyneuropathy in an Ashkenazic Jewish kindred.
Transthyretin Pro55, a variant associated with early-onset, aggressive, diffuse amyloidosis with cardiac and neurologic involvement.
Transthyretin Ser 6 gene frequency in individuals without amyloidosis.
Transthyretin Ser-44 mutation in a case with vitreous amyloidosis.
Transthyretin stability as a key factor in amyloidogenesis: X-ray analysis at atomic resolution.
Transthyretin stabilization activity of the catechol-O-methyltransferase inhibitor tolcapone (SOM0226) in hereditary ATTR amyloidosis patients and asymptomatic carriers: proof-of-concept study
Transthyretin Stabilization by AG10 in Symptomatic Transthyretin Amyloid Cardiomyopathy.
Transthyretin Stabilization: An Emerging Strategy for the Treatment of Alzheimer's Disease?
Transthyretin Stabilizer Is Associated With Expanding Apical Sparing Area and Improving Global Cardiac Function in a Patient With Wild-Type Cardiac Amyloidosis.
Transthyretin suppresses the toxicity of oligomers formed by misfolded proteins in vitro.
Transthyretin Tyr69-to-Ile mutation (double-nucleotide substitution in codon 69) in a Japanese familial amyloidosis patient with cardiomyopathy and carpal tunnel syndrome.
Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly African Americans.
Transthyretin V122I amyloidosis with clinical and histological evidence of amyloid neuropathy and myopathy.
Transthyretin VAL107, a new variant associated with familial cardiac and neuropathic amyloidosis.
Transthyretin Val122Ile amyloidosis associated with isolated gastrointestinal disease and bowel rupture in a Caucasian woman.
Transthyretin Val122Ile, accumulated Abeta, and inclusion-body myositis aspects in cultured muscle.
Transthyretin Val30Met mutation in an African American with cardiac amyloidosis.
Transthyretin valine-94-alanine, a novel variant associated with late-onset systemic amyloidosis with cardiac involvement.
Transthyretin-derived amyloidosis: Probably a common cause of lumbar spinal stenosis.
Transthyretin-derived senile systemic amyloidosis: clinicopathologic and structural considerations.
Transthyretin-related amyloid in a saphenous vein. Histological diagnosis in a patient undergoing coronary artery bypass surgery.
Transthyretin-related amyloidoses and the heart: a clinical overview.
Transthyretin-stabilising mutation T119M is not associated with protection against vascular disease or death in the UK Biobank.
Trapping of palindromic ligands within native transthyretin prevents amyloid formation.
Treatment of cardiac transthyretin amyloidosis: an update.
Treatment of hereditary and acquired forms of transthyretin amyloidosis in the era of personalized medicine: the role of randomized controlled trials.
Treatment success in hereditary transthyretin amyloidosis.
True, true unrelated? Coexistence of Waldenström macroglobulinemia and cardiac transthyretin amyloidosis.
TTR gene silencing therapy in post liver transplant hereditary ATTR amyloidosis patients.
TTRMDB: A database for structural and functional analysis on the impact of SNPs over transthyretin (TTR) using bioinformatic tools.
Tuning transthyretin amyloidosis inhibition properties of iododiflunisal by combinatorial engineering of the nonsalicylic ring substitutions.
Two transthyretin mutations (glu42gly, his90asn) in an Italian family with amyloidosis.
Two types of amyloidosis presenting in a single patient: a case series.
Two-tiered DNA-based diagnosis of transthyretin amyloidosis reveals two novel point mutations.
Tyr78Phe Transthyretin Mutation with Predominant Motor Neuropathy as the Initial Presentation.
Ultrastructure in Transthyretin Amyloidosis: From Pathophysiology to Therapeutic Insights.
Uncovering the Mechanism of Aggregation of Human Transthyretin.
Uncovering the Neuroprotective Mechanisms of Curcumin on Transthyretin Amyloidosis.
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.
Understanding the Disease Course and Therapeutic Benefit of Tafamidis Across Real-World Studies of Hereditary Transthyretin Amyloidosis with Polyneuropathy: A Proof of Concept for Integrative Data Analytic Approaches.
Unexplained cardiac failure leading to the identification of a Belgian family affected by hereditary amyloidosis.
Unfolding and aggregation of transthyretin by the truncation of 50 N-terminal amino acids.
Unfolding Cardiac Amyloidosis - From Pathophysiology to Cure.
United network for organ sharing outcomes after heart transplantation for al compared to ATTR cardiac amyloidosis.
Unmasking Early Wild-Type Transthyretin Amyloidosis Cardiomyopathy in a Patient With Refractory Atrial Fibrillation and Unremarkable Cardiac Imaging.
Untangling the physiology of transthyretin cardiac amyloidosis by leveraging echocardiographically derived pressure-volume indices.
Unusual high 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) tracer deposition on a heart scintigraphy in a patient with AL amyloidosis: A case report.
Unusual Pain Disorders - What Can Be Learned from Them?
Unveiling outcomes in coexisting severe aortic stenosis and transthyretin cardiac amyloidosis.
Unveiling transthyretin cardiac amyloidosis and its predictors among elderly patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.
Unveiling wild-type transthyretin cardiac amyloidosis as a significant and potentially modifiable cause of heart failure with preserved ejection fraction.
Update in recent clinical trials in heart failure.
Updates in Cardiac Amyloidosis Diagnosis and Treatment.
Upper limb onset of hereditary transthyretin amyloidosis is common in non-endemic areas.
Uptake of aggregating transthyretin by fat body in a Drosophila model for TTR-associated amyloidosis.
Use of a microchip device coupled with mass spectrometry for ligand screening of a multi-protein target.
Use of biomarkers to diagnose and manage cardiac amyloidosis.
Use of fluorine-18 sodium fluoride for the diagnosis of transthyretin cardiac amyloidosis: The birth of a new technique.
Use of Implantable Electronic Devices in Patients With Cardiac Amyloidosis.
Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin.
Use of Ventilatory Efficiency Slope as a Marker for Increased Mortality in Wild-Type Transthyretin Cardiac Amyloidosis.
Usefulness of (99m)Tc-HMDP scintigraphy for the etiologic diagnosis and prognosis of cardiac amyloidosis.
Usefulness of Combining Electrocardiographic and Echocardiographic Findings and Brain Natriuretic Peptide in Early Detection of Cardiac Amyloidosis in Subjects With Transthyretin Gene Mutation.
Usefulness of electron microscopy in the diagnosis of wild-type transthyretin cardiac amyloidosis.
Usefulness of plasma B-type natriuretic peptide as a prognostic marker of cardiac function in senile systemic amyloidosis and in familial amyloidotic polyneuropathy.
Utility of 99 mTc-Pyrophosphate Scintigraphy in Diagnosing Transthyretin Cardiac Amyloidosis in Real-World Practice.
Utility of Kumamoto Criteria in Diagnosing Transthyretin Cardiac Amyloidosis in Real-World Practice.
Utility of Kumamoto Criteria in Diagnosing Transthyretin Cardiac Amyloidosis in Real-World Practice?- Reply.
Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients.
Val50Met hereditary transthyretin amyloidosis: not just a medical problem, but a psychosocial burden.
Validation of the Kumamoto criteria for prediction of 99m technetium pyrophosphate scintigraphy positivity as a strategy for diagnosis of transthyretin cardiac amyloidosis: A retrospective cohort study in Kochi.
Value of Longitudinal Strain to Identify Wild-Type Transthyretin Amyloidosis in Patients With Aortic Stenosis.
Value of natriuretic peptides and tissue Doppler imaging in the estimation of left ventricular filling pressure in patients with cardiac amyloidosis.
Variable presentations of TTR-related familial amyloid polyneuropathy in seventeen patients.
Variant transthyretin (TTR) amyloidosis in Argentina. Detection of the trait by electrospray ionization mass spectrometry of lyophilized TTR immunoprecipitate.
Variant Transthyretin Amyloidosis (ATTRv) in Hungary: First Data on Epidemiology and Clinical Features.
Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans.
Variation in amount of wild-type transthyretin in different fibril and tissue types in ATTR amyloidosis.
Vascular endothelial growth factor helps differentiate neuropathies in rare plasma cell dyscrasias.
Visualization of multiple organ amyloid involvement in systemic amyloidosis using (11)C-PiB PET imaging.
Vitreal deposits in Val71Ala transthyretin amyloidosis.
Vitreous amyloidosis after liver transplantation in patients with familial amyloid polyneuropathy: ocular synthesis of mutant transthyretin.
Vitreous amyloidosis associated with homozygosity for the transthyretin methionine-30 gene.
Vitreous amyloidosis in alanine 71 transthyretin mutation.
Vitreous amyloidosis in familial amyloidotic polyneuropathy. Report of a case with the Val30Met transthyretin mutation.
Vitreous amyloidosis in two large mainland Chinese kindreds resulting from transthyretin variant Lys35Thr and Leu55Arg.
Vitreous amyloidosis in two sisters as the indication of transthyretin-related familial form of systemic amyloidosis among liver transplantation candidates.
Vitreous amyloidosis with autonomic neuropathy of the digestive tract associated with a novel transthyretin p.Gly87Arg variant in a Bangladeshi patient: a case report.
Vitreous amyloidosis without systemic or familial involvement.
When and how do patients with cardiac amyloidosis die?
When to suspect transthyretin amyloidosis in cases of isolated vitreous opacities?
Where Neurosurgery Meets Heart Failure: A Case Report of a Patient with Amyloid Transthyretin Wild Type in the Ligamentum Flavum and Cardiac Tissue with Bilateral Carpal Tunnel Syndrome.
White matter disorders with autosomal dominant heredity: a review with personal clinical case studies and their MRI findings.
Why are some amyloidoses systemic? Does hepatic "chaperoning at a distance" prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?
Widespread Cardiac and Vasomotor Autonomic Dysfunction in Non-Val30Met Hereditary Transthyretin Amyloidosis.
Wild type transthyretin amyloidosis, a reason not to be forgotten for heart failure of preserved ejection fraction in the elderly.
Wild type transthyretin amyloidosis: Don't miss diagnosis!
Wild type transthyretin cardiac amyloidosis in a young individual: A case report.
Wild-type transthyretin amyloid cardiomyopathy complicated by spinal canal stenosis, carpal tunnel syndrome, and rotator cuff tears: a case report.
Wild-type Transthyretin Amyloid Myopathy With an Inclusion Body Myositis Phenotype.
Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction.
Wild-Type Transthyretin Amyloidosis in Female Patients?- Consideration of Sex Differences.
Wild-Type Transthyretin Amyloidosis Occurring in the Ligamentum Flavum of the Cervicothoracic Spine.
Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), previously known as senile cardiac amyloidosis: clinical presentation, diagnosis, management and emerging therapies.
Wild-type transthyretin cardiac amyloidosis diagnosed in a patient in his 50s.
Wild-Type Transthyretin Cardiac Amyloidosis: Novel Insights From Advanced Imaging.
Wild-type transthyretin cardiac amyloidosis: When is a rare disease no longer a rare disease?
Wild-type TTR amyloidosis among patients with unexplained heart failure and systolic LV dysfunction.
Yield of Noncardiac Biopsy for the Diagnosis of Transthyretin Cardiac Amyloidosis.
[18F]-Florbetaben PET/CT for Differential Diagnosis Among Cardiac Immunoglobulin Light Chain, Transthyretin Amyloidosis, and Mimicking Conditions.
[18F]-NaF PET/CT imaging in cardiac amyloidosis.
[A selection of advances in neuromuscular medicine].
[AA Amyloidosis: recent knowledges on pathophysiology]
[Aged onset of amyloidosis caused by transthyretin gene mutations]
[Amyloid from insulin treatment: a pitfall for the pathologist and the diabetologist].
[Amyloid neuropathy resulting from an unknown protein.]
[Amyloidosis and aging]
[Amyloidosis and neurological disorders: Treatable amyloidosis].
[Antisense therapies for neurological diseases].
[Application to transthyretin analysis]
[Bone seeking tracers' scintigraphy for the diagnosis of transthyretin cardiac amyloidosis].
[Cardiac amyloidosis: How to recognize them and manage them?]
[Cardiac amyloidosis: Recent advances in the diagnosis and therapy].
[Cardiac amyloidosis: review of the literature]
[Cardiac amyloidosis]
[Cardiac amyloidosis].
[Cardiac manifestations of amyloidosis by deposits of transthyretin and apolipoprotein A1. Report of 3 families]
[Cardiac scintigraphy-centered diagnostic process in transthyretin cardiac amyloidosis].
[Classification of amyloidosis].
[Clinical characteristics of Hungarian-type familial meningo-cerebrovascular amyloidosis]
[Clinical diversity, diagnosis and treatment of hereditary amyloid neuropathy].
[Current approaches for treatment of hereditary transthyretin amyloidosis (ATTR)].
[Experience with tafamidis in a patient with transthyretin amyloidosis].
[Familial amyloidosis]
[Familial transthyretin amyloidosis with Gly47Arg mutation and cardiac involvement: a case report].
[Familial transthyretin amyloidosis]
[Fibril-forming proteins: the amyloidosis. New hopes for a disease that cardiologists must know]
[Gene therapy in familial amyloidotic polyneuropathy by single-stranded oligonucleotides (SSOs)]
[Hereditary amyloid cardiomyopathy related to a mutation at transthyretin protein number 111. A clinical, genetic and echocardiographic study of an affected Danish family]
[Hereditary and acquired transthyretin-mediated amyloidosis].
[Hereditary cardiac amyloidosis with transthyretin mutations : A cause of sudden death.]
[Histological and immunohistochemical examinations in the diagnosis of hepatic amyloidosis].
[In memoriam Prof. Dr. Ferenc Garzuly (1937-2021)].
[Indications for simultaneous origin of a German and American family with type II hereditary amyloid neuropathy]
[Multiple nodular pulmonary amyloidosis complicated with Sjögren syndrome]
[Non-invasive diagnosis of cardiac amyloidosis due to transthyretin. Case report].
[Novel tool for diagnosis of amyloidosis]
[Optimization of the immunohistochemical diagnosis of AL amyloidosis using novel antibodies].
[Pathogenesis and therapy for transthyretin related amyloidosis]
[Perioperative management for liver transplant in a patient with familial amyloid polyneuropathy with heart involvement.]
[Problems of diagnostics and treatment of transtiretinum amyloidosis with destruction of the heart in the elderly: Clinical experience.]
[Progress in the diagnosis and treatment of cardiac amyloidosis].
[Senile systemic amyloidosis: definition, diagnosis, why thinking about?].
[Senile systemic amyloidosis].
[Suspected cardiac amyloidosis - diagnostic steps for evaluation].
[The informative value of oral mucosal biopsy for the diagnosis of systemic amyloidosis].
[Transthyretin amyloidoses]
[Transthyretin amyloidosis in a cohort of old and very old patients with chronic heart failure].
[Transthyretin Arg-83 mutation in vitreous amyloidosis]
[Transthyretin cardiac amyloidosis].
[Transthyretin-related amyloidotic cardiomyopathy: looking for the etiological treatment].
[Treatment strategies of patients with transthyretin amyloidosis cardiomyopathy].
[What gnaws at the heart and gets on the nerves].
Amyloidosis, Familial
99mTc-DPD scintigraphy in transthyretin-related familial amyloidotic polyneuropathy.
A case of hereditary amyloidosis transthyretin variant Met 30 with amyloid cardiomyopathy, less polyneuropathy, and the presence of giant cells.
A case of renal and splenic LECT 2 amyloidosis: A recently recognized cause of renal and systemic amyloidosis.
A new genetic variant of hereditary apolipoprotein A-I amyloidosis: a case-report followed by discussion of diagnostic challenges and therapeutic options.
A new mutation (TTR Ala-47) in the transthyretin gene associated with hereditary amyloidosis.
A new transthyretin mutation associated with amyloid cardiomyopathy.
A new transthyretin variant (Ser23Asn) associated with familial amyloidosis in a Portuguese patient.
A Patient With Hereditary ATTR and a Novel AGel p.Ala578Pro Amyloidosis.
A possible role for miRNA silencing in disease phenotype variation in Swedish transthyretin V30M carriers.
A prospective evaluation of the transthyretin Ile122 allele frequency in an African-American population.
Advanced glycation end products (AGE) and the receptor for AGE are present in gastrointestinal tract of familial amyloidotic polyneuropathy patients but do not induce NF-kappaB activation.
Ageing and amyloid fibrillogenesis: lessons from apolipoprotein AI, transthyretin and islet amyloid polypeptide.
Amyloid diseases of the heart: current and future therapies.
Amyloid fibril protein in familial amyloidosis with cranial neuropathy and corneal lattice dystrophy (FAP type IV) is related to transthyretin.
An overview of drugs currently under investigation for the treatment of transthyretin-related hereditary amyloidosis.
Anesthetic management of a combined heart and liver transplantation in an amyloidotic patient: a case report.
Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity.
Capture of a dimeric intermediate during transthyretin amyloid formation.
Cardiac amyloidosis with gastrointestinal involvement: a case report.
Cardiac amyloidosis: a review and report of a new transthyretin (prealbumin) variant.
Clinical 3-D Gait Assessment of Patients With Polyneuropathy Associated With Hereditary Transthyretin Amyloidosis.
Clinical characteristics in patients with hereditary amyloidosis with Glu54Gln transthyretin identified in the Romanian population.
Clinical manifestations in hereditary amyloidosis with the variant Glu54Gln transthyretin.
Clinical manifestations in hereditary amyloidosis with the variant Glu54Gln transthyretin: a comment.
Clinical Presentation, Diagnosis and Treatment of TTR Amyloidosis.
Current treatment in cardiac amyloidosis.
Current trends in diagnosis and management of cardiac amyloidosis.
Deposits on Retinal Surface Seen on OCT in Ocular Amyloidosis.
Description of transthyretin S50A, S52P and G47A mutations in familial amyloidosis polyneuropathy.
Diagnosis and therapeutic approaches to transthyretin amyloidosis.
Discovery of ?-Mangostin as an Amyloidogenesis Inhibitor.
Early diagnostic tools in hereditary amyloidosis related to transthyretin (hATTR) V30M autonomic neuropathy.
Effect on disability and safety of Tafamidis in late onset of Met30 transthyretin familial amyloid polyneuropathy.
Electrochemical skin conductance in hereditary amyloidosis related to transthyretin V30M - a promising tool to assess treatment efficacy?
Electromyographic findings in transthyretin (TTR)-related familial amyloid polyneuropathy (FAP).
Erythropoietin production by distal nephron in normal and familial amyloidotic adult human kidneys.
Familial amyloidosis in a large Spanish kindred resulting from a D38V mutation in the transthyretin gene.
Familial amyloidosis with polyneuropathy type 1 caused by transthyretin mutation Val50Met (Val30Met): 4 cases in a non-endemic area.
Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells.
Haplotype analysis of common transthyretin mutations.
Hereditary amyloidosis related to transthyretin V30M: disease progression in treated and untreated patients.
Hereditary amyloidosis with cardiomyopathy caused by the novel variant transthyretin A36D.
Homozygosity and heterozygosity for the transthyretin Leu64 mutation: clinical, biochemical and molecular findings.
Identification of transthyretin variants by sequential proteomic and genomic analysis.
Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients.
Inhibition of transthyretin-met30 expression using Inosine(15.1)-Hammerhead ribozymes in cell culture.
Inosine(15.1) hammerhead ribozymes for targeting the transthyretin-30 mutation.
Investigation of AGE, their receptor and NF-kappaB activation and apoptosis in patients with ATTR and Gelsolin amyloidosis.
Liver transplantation for hereditary transthyretin amyloidosis.
Long-term effects of liver transplantation on small-fiber dysfunction in Japanese transthyretin (ATTR) V30M hereditary amyloidosis with polyneuropathy (FAP).
Low Prevalence of Clinically Apparent Cardiac Amyloidosis Among Carriers of Transthyretin V122I Variant in a Large Electronic Medical Record.
Mechanisms of transthyretin amyloidogenesis. Antigenic mapping of transthyretin purified from plasma and amyloid fibrils and within in situ tissue localizations.
Mutation and transcription analysis of transthyretin gene in Italian families with hereditary amyloidosis: a putative novel hot spot' in codon 47.
Neuropathy Associated with Systemic Amyloidosis.
Normal transthyretin and synthetic transthyretin fragments form amyloid-like fibrils in vitro.
Novel methods for detecting amyloidogenic proteins in transthyretin related amyloidosis.
Novel transthyretin missense mutation (Thr34) in an Italian family with hereditary amyloidosis.
Ocular Manifestations of Familial Transthyretin Amyloidosis.
Orthotopic liver transplantation for hereditary fibrinogen amyloidosis.
Patisiran in hATTR Amyloidosis: Six-Month Latency Period before Efficacy.
Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.
Postmortem findings in two familial amyloidosis patients with transthyretin variant Asp38Ala.
Pupil abnormality in amyloidosis with autonomic neuropathy.
Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS.
Rare variant (p.Ser43Asn) of familial transthyretin amyloidosis associated with isolated cardiac phenotype: A case series with literature review.
Regional difference and similarity of familial amyloidosis with polyneuropathy in France.
Screening and biochemical characterization of transthyretin variants in the Portuguese population.
Serum amyloid P component scintigraphy in familial amyloid polyneuropathy: regression of visceral amyloid following liver transplantation.
Speckle Tracking and Transthyretin Amyloid Cardiomyopathy.
STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein.
Targeting transthyretin - Mechanism-based treatment approaches and future perspectives in hereditary amyloidosis.
The premortem recognition of systemic senile amyloidosis with cardiac involvement.
The Transthyretin Amyloidosis Outcomes Survey (THAOS) registry: design and methodology.
The transthyretin cDNA sequence is normal in transthyretin-derived senile systemic amyloidosis.
The use of intravitreal ranibizumab to treat neovascular glaucoma because of retinal amyloid angiopathy in familial amyloidosis transthyretin v30m related.
Three Turkish families with different transthyretin mutations.
Transthyretin (prealbumin) gene in human primary hepatic cancer.
Transthyretin amyloidosis: a little history of hereditary amyloidosis.
Transthyretin amyloidosis: a tale of weak interactions.
Transthyretin Cardiac Amyloidosis.
Transthyretin proteins regulate angiogenesis by conferring different molecular identities to endothelial cells.
Transthyretin Tyr69-to-Ile mutation (double-nucleotide substitution in codon 69) in a Japanese familial amyloidosis patient with cardiomyopathy and carpal tunnel syndrome.
TRANSTHYRETIN V30M FAMILIAL AMYLOIDOSIS PRESENTING AS ISOLATED RETINAL ANGIOPATHY.
Transthyretin-associated neuropathic amyloidosis. Pathogenesis and treatment.
Transthyretin-Related Hereditary Amyloidosis in a Chinese Family with TTR Y114C Mutation.
TTR familial amyloid polyneuropathy: does a mitochondrial polymorphism entirely explain the parent-of-origin difference in penetrance?
Two transthyretin variants (TTR Ala-49 and TTR Gln-89) in two Sicilian kindreds with hereditary amyloidosis.
Tyr78Phe Transthyretin Mutation with Predominant Motor Neuropathy as the Initial Presentation.
Vitreous amyloidosis without systemic or familial involvement.
[Can amyloidosis regress?]
[Clinical case: non familial vitreous amyloidosis].
[Clinical characteristics of Hungarian-type familial meningo-cerebrovascular amyloidosis]
[Hereditary amyloidoses associated with transthyretin mutations]
[Neurology].
Anemia
Low erythropoietin production in familial amyloidosis TTR V30M is not related with renal congophilic amyloid deposition. A clinicopathologic study of twelve cases.
Proteomic analysis of plasma proteins of high-flux haemodialysis and on-line haemodiafiltration patients reveals differences in transthyretin levels related with anaemia.
Unwanted road to anaemia in transthyretin familial amyloid polyneuropathy may continue irrespective of tafamidis treatment.
Aneurysm, Dissecting
Acute aortic dissection associated with wild-type transthyretin amyloid.
Angina, Unstable
[Difference expressed protein study on unstable angina blood-stasis syndrome by fluorescence labelling method]
Aortic Valve Stenosis
Aortic stenosis and transthyretin cardiac amyloidosis: the chicken or the egg?
Aortic stenosis, transcatheter aortic valve replacement and transthyretin cardiac amyloidosis: are we progressively unraveling the tangle?
Association between aortic stenosis and hereditary transthyretin amyloidosis.
Cardiac amyloidosis in non-transplant cardiac surgery.
Dangerous relationships: aortic stenosis and transthyretin cardiac amyloidosis.
Early Progression of Aortic Stenosis Associated With Iatrogenic Variant Transthyretin Amyloidosis After Domino Liver Transplantation.
Estimating cancer risk from 99mTc pyrophosphate imaging for transthyretin cardiac amyloidosis.
Impact of afterload and infiltration on coexisting aortic stenosis and transthyretin amyloidosis.
In the midst of a dangerous intersection with unclear therapeutic strategies: a challenging case of severe aortic stenosis.
Light-chain and transthyretin cardiac amyloidosis in severe aortic stenosis: prevalence, screening possibilities, and outcome.
Occult Transthyretin Cardiac Amyloid in Severe Calcific Aortic Stenosis: Prevalence and Prognosis in Patients Undergoing Surgical Aortic Valve Replacement.
Prognostic assessment of relative apical sparing pattern of longitudinal strain for severe aortic valve stenosis.
Prognostic Significance of Occult Transthyretin Cardiac Amyloidosis in Patients With Severe Aortic Stenosis Undergoing Surgical Aortic Valve Replacement: An Unrecognized Disease Modifier.
Recognizing Transthyretin Cardiac Amyloidosis in Patients With Aortic Stenosis: Impact on Prognosis.
Subthreshold Aortic Valve Calcium Scores in Severe Aortic Stenosis and Transthyretin Cardiac Amyloidosis.
Transthyretin cardiac amyloid and aortic stenosis in the elderly, the role of nuclear imaging.
Transthyretin Cardiac Amyloidosis and Aortic Stenosis: Connection and Therapeutic Implications.
Transthyretin cardiac amyloidosis in aortic stenosis: Prevalence, diagnostic challenges, and clinical implications.
Transthyretin cardiac amyloidosis in patients with severe aortic stenosis.
Unveiling outcomes in coexisting severe aortic stenosis and transthyretin cardiac amyloidosis.
Unveiling transthyretin cardiac amyloidosis and its predictors among elderly patients with severe aortic stenosis undergoing transcatheter aortic valve replacement.
Value of Longitudinal Strain to Identify Wild-Type Transthyretin Amyloidosis in Patients With Aortic Stenosis.
Arrhythmias, Cardiac
Cardiac amyloidosis: An underdiagnosed/underappreciated disease.
Continuous development of arrhythmia is observed in Swedish transplant patients with familial amyloidotic polyneuropathy (amyloidogenic transthyretin Val30Met variant).
Reduced left atrial myocardial deformation irrespective of cavity size: a potential cause for atrial arrhythmia in hereditary transthyretin amyloidosis.
Arteriosclerosis
Significance of the amyloidogenic transthyretin Val 122 Ile allele in African Americans in the Arteriosclerosis Risk in Communities (ARIC) and Cardiovascular Health (CHS) Studies.
Arthritis
Autoimmune response to transthyretin in juvenile idiopathic arthritis.
Arthritis, Experimental
Proteins of rat serum V: adjuvant arthritis and its modulation by nonsteroidal anti-inflammatory drugs.
Arthritis, Juvenile
Autoimmune response to transthyretin in juvenile idiopathic arthritis.
Arthritis, Rheumatoid
A case of wild-type transthyretin cardiac amyloidosis with rheumatoid arthritis.
Amyloidosis and Ocular Involvement: an Overview.
Identification of Autoantibodies against Transthyretin for the Screening and Diagnosis of Rheumatoid Arthritis.
Retraction: Identification of Autoantibodies against Transthyretin for the Screening and Diagnosis of Rheumatoid Arthritis.
Transthyretin as a potential serological marker for the diagnosis of patients with early rheumatoid arthritis.
Astrocytoma
Transthyretin receptors on human astrocytoma cells.
Ataxia
A novel amyloidogenic transthyretin variant, Gly53Ala, associated with intermittent headaches and ataxia.
Atherosclerosis
Inflammatory and Molecular Pathways in Heart Failure-Ischemia, HFpEF and Transthyretin Cardiac Amyloidosis.
Atrial Fibrillation
Anticoagulation with warfarin compared to novel oral anticoagulants for atrial fibrillation in adults with transthyretin cardiac amyloidosis: comparison of thromboembolic events and major bleeding.
Atrial fibrillation ablation in patients with transthyretin cardiac amyloidosis.
Atrial Fibrillation and Central Nervous Complications in Liver Transplanted Hereditary Transthyretin Amyloidosis Patients.
Atrial Fibrillation and Ischemic Stroke With the Amyloidogenic V122I Transthyretin Variant Among Black Americans.
Atrial Fibrillation in Transthyretin Cardiac Amyloidosis: Predictors, Prevalence, and Efficacy of Rhythm Control Strategies.
Atrial Fibrillation in Transthyretin Cardiac Amyloidosis: The Growing Need to Look Forward.
Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology.
Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience.
Management Strategies for Atrial Fibrillation and Flutter in Patients with Transthyretin Cardiac Amyloidosis.
Prevalence and Outcomes of p.Val142Ile TTR Amyloidosis Cardiomyopathy: A Systematic Review.
Prevalence of Atrial Fibrillation and Thromboembolic Risk in Wild-Type Transthyretin Amyloid Cardiomyopathy.
Stroke risk and atrial mechanical dysfunction in cardiac amyloidosis.
Unmasking Early Wild-Type Transthyretin Amyloidosis Cardiomyopathy in a Patient With Refractory Atrial Fibrillation and Unremarkable Cardiac Imaging.
Bile Duct Neoplasms
Plasma retinol transport system and taste acuity in patients with obstructive jaundice.
Blindness
Failure of Tafamidis to Halt Progression of Ala36Pro TTR Oculomeningovascular Amyloidosis.
Blister
Ruptured Bullae: A Case of Transthyretin Cardiac Amyloidosis.
Bradycardia
Use of Implantable Electronic Devices in Patients With Cardiac Amyloidosis.
Brain Ischemia
Cerebrospinal fluid transthyretin neuroprotection in a mouse model of brain ischemia.
Combined proteomic approach with SELDI-TOF-MS and peptide mass fingerprinting identified the rapid increase of monomeric transthyretin in rat cerebrospinal fluid after transient focal cerebral ischemia.
Evidence for synergistic action of transthyretin and IGF-I over the IGF-I receptor.
Failure of Tafamidis to Halt Progression of Ala36Pro TTR Oculomeningovascular Amyloidosis.
Transthyretin provides trophic support via megalin by promoting neurite outgrowth and neuroprotection in cerebral ischemia.
Brain Neoplasms
Faecal proteome in clinically healthy dogs and cats: Findings in pooled faeces from 10 cats and 10 dogs.
ProApolipoprotein A1: a serum marker of brain metastases in lung cancer patients.
Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation.
Transthyretin immunoreactivity in choroid plexus neoplasms and brain metastases.
[Immunohistochemical study on distribution of transthyretin in normal human brain tissue and tumors]
Breast Neoplasms
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity.
Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.
PEL: an unbiased method for estimating age-dependent genetic disease risk from pedigree data unselected for family history.
Two-dimensional electrophoretic proteome study of serum thermostable fraction from patients with various tumor conditions.
Bronchiectasis
Nutritional depletion in patients on long-term oxygen therapy and/or home mechanical ventilation.
Bronchitis
[Bronchoalveolar lavage. The humoral parameter spectrum in bronchial carcinoma and chronic bronchitis]
Bronchitis, Chronic
[Bronchoalveolar lavage. The humoral parameter spectrum in bronchial carcinoma and chronic bronchitis]
Brugada Syndrome
Therapeutic Strategies Targeting Inherited Cardiomyopathies.
Bulbo-Spinal Atrophy, X-Linked
The Italian neuromuscular registry: a coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage.
Bundle-Branch Block
Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block.
Carcinogenesis
HCC Specific Protein Network Involving Interactions of EGFR with A-Raf and Transthyretin: Experimental Analysis and Computational Biology Correlates.
Carcinoma
Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach.
The choroid plexus carcinomas of childhood: histopathology, immunocytochemistry and clinicopathological correlations.
The use of immunomorphology to differentiate choroid plexus tumors from metastatic carcinomas.
Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas.
Transthyretin, identified by proteomics, is overabundant in pancreatic juice from pancreatic carcinoma and originates from pancreatic islets.
Transthyretin--an explanation of "anomalous" serum thyroid hormone values in severe illness?
Tumors of the choroid plexus.
[Prognostic markers in the histopathological diagnosis of tumors of the choroid plexus]
Carcinoma, Bronchogenic
Tracheobronchial amyloidosis.
[Bronchoalveolar lavage. The humoral parameter spectrum in bronchial carcinoma and chronic bronchitis]
Carcinoma, Embryonal
Induction of the expression of retinol-binding protein and transthyretin in F9 embryonal carcinoma cells differentiated to embryoid bodies.
Carcinoma, Hepatocellular
Adenovirus-mediated hepatocyte nuclear factor-4alpha overexpression maintains liver phenotype in cultured rat hepatocytes.
Clinical significance of serum transthyretin level in patients with hepatocellular carcinoma.
Decreased expression of hepatocyte nuclear factor 3 alpha during the acute-phase response influences transthyretin gene transcription.
Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
Differential regulation of hepatocyte-enriched transcription factors explains changes in albumin and transthyretin gene expression among hepatoma cells.
Functional activity of hepatocyte nuclear factor-1 is specifically decreased in amino acid-limited hepatoma cells.
Novel mutations in transthyretin gene associated with hepatocellular carcinoma.
Receptor-mediated uptake and internalization of transthyretin.
Studies on the synthesis and secretion of transthyretin by the human hepatoma cell line Hep G2.
Carcinoma, Non-Small-Cell Lung
Effect and Mechanism of Transthyretin over-Expression on Proliferation and Cell Cycle of Lung Cancer A549 Cells.
Prognostic impact of serum transthyretin in patients with non-small cell lung cancer.
Carcinoma, Ovarian Epithelial
Postoperative recurrence of epithelial ovarian cancer patients and chemoresistance related protein analyses.
Proteomic biomarkers apolipoprotein A1, truncated transthyretin and connective tissue activating protein III enhance the sensitivity of CA125 for detecting early stage epithelial ovarian cancer.
Carcinoma, Renal Cell
Amyloid and peripheral nervous system disease.
Receptor-mediated uptake and internalization of transthyretin.
Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas.
Cardiac Conduction System Disease
Reduced myocardial 123-iodine metaiodobenzylguanidine uptake: a prognostic marker in familial amyloid polyneuropathy.
Cardiomegaly
Diagnostic utility of cardiac troponin T level in patients with cardiac amyloidosis.
Cardiomyopathies
6MWT performance correlates with peripheral neuropathy but not with cardiac involvement in patients with hereditary transthyretin amyloidosis (hATTR).
99mTechnetium pyrophosphate scintigraphy with cadmium zinc telluride cameras is a highly sensitive and specific imaging modality to diagnose transthyretin cardiac amyloidosis.
A case of hereditary amyloidosis transthyretin variant Met 30 with amyloid cardiomyopathy, less polyneuropathy, and the presence of giant cells.
A case of transthyretin amyloidosis with myopathy, neuropathy, and cardiomyopathy resulting from an exceedingly rare mutation transthyretin Ala120Ser (c.418G?>?T, p.Ala140Ser).
A case of unilateral shoulder joint hydrarthrosis with wild-type amyloidogenic transthyretin amyloidosis.
A case report of an infiltrative cardiomyopathy in everyday practice: a specific cause that cannot be missed in the elderly.
A clinical, echocardiographic and genetic characterization of a Danish kindred with familial amyloid transthyretin methionine 111 linked cardiomyopathy.
A Danish kindred with familial amyloid cardiomyopathy revisited: identification of a mutant transthyretin-methionine111 variant in serum from patients and carriers.
A Heart too Stiff to Beat: A Case of Familial Transthyretin Amyloidosis Cardiomyopathy.
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells.
A look into amyloid formation by transthyretin: aggregation pathway and a novel kinetic model.
A machine learning model for identifying patients at risk for wild-type transthyretin amyloid cardiomyopathy.
A Narrative Review of the Role of Transthyretin in Health and Disease.
A new amyloidogenic transthyretin variant (Val122Ala) found in a compound heterozygous patient.
A new staging system for cardiac transthyretin amyloidosis.
A new transthyretin mutation associated with amyloid cardiomyopathy.
A new transthyretin variant (Glu61Gly) associated with cardiomyopathy.
A new transthyretin variant (Ser23Asn) associated with familial amyloidosis in a Portuguese patient.
A novel ATTR L32V mutation causes familial amyloid polyneuropathy in a Bolivian family.
A novel variant of transthyretin (Glu89Lys) associated with familial amyloidotic polyneuropathy.
A rare transthyretin mutation (Asp18Glu) associated with cardiomyopathy.
A serine protease secreted from Bacillus subtilis cleaves human plasma transthyretin to generate an amyloidogenic fragment.
A transthyretin variant, Asp18Asn, associated with amyloid cardiomyopathy: a new African-American variant?
Abdominal fat pad biopsies exhibit good diagnostic accuracy in patients with suspected transthyretin amyloidosis.
Advances in Diagnosis and Treatment of Cardiac and Renal Amyloidosis.
Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: a possible model for senile systemic amyloidosis.
Amyloid cardiomyopathy in a large integrated health care system.
Amyloid Cardiomyopathy in Hereditary Transthyretin V30M Amyloidosis - Impact of Sex and Amyloid Fibril Composition.
Amyloid Cardiomyopathy in the Rare Transthyretin Tyr78Phe Mutation.
Amyloid cardiomyopathy: a hidden heart failure cause that is often misdiagnosed.
Amyloid Fibril Composition as a Predictor of Development of Cardiomyopathy After Liver Transplantation for Hereditary Transthyretin Amyloidosis.
Amyloid Polyneuropathy Caused By Wild-Type Transthyretin.
Amyloidogenic and anti-amyloidogenic properties of recombinant transthyretin variants.
An Italian family with Ala-47 transthyretin mutation associated with cardiomyopathy and polyneuropathy.
Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry.
Beneficial Effect of Pimobendan for Severe Heart Failure Due to Transthyretin Cardiac Amyloidosis.
Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy.
Best Practices in Specialized Amyloidosis Centers in the United States: A Survey of Cardiologists, Nurses, Patients, and Patient Advocates.
Bio-Profiling of Transthyretin Amyloid Cardiomyopathy.
Biopsy Evidence of Sequential Transthyretin and Immunoglobulin Light-Chain Cardiac Amyloidosis in the Same Patient.
Burden of hereditary transthyretin amyloidosis on quality of life.
Cardiac amyloidosis: An underdiagnosed/underappreciated disease.
Cardiac Amyloidosis: Evolving Diagnosis and Management: A Scientific Statement From the American Heart Association.
Cardiac amyloidosis: from clinical suspicion to morphological diagnosis.
Cardiac amyloidosis: Updates in diagnosis and management.
Cardiac Scintigraphy With Technetium-99m-Labeled Bone-Seeking Tracers for Suspected Amyloidosis: JACC Review Topic of the Week.
Cardiac transthyretin amyloidosis.
Cardiomyopathy in a Japanese family with the Glu61Lys transthyretin variant: a new phenotype.
Cardiomyopathy in Swedish patients with the Gly53Glu and His88Arg transthyretin variants.
Causes of Cardiovascular Hospitalization and Death in Patients With Transthyretin Amyloid Cardiomyopathy (from the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial [ATTR-ACT]).
Change in N-terminal pro-B-type natriuretic peptide at 1 year predicts mortality in wild-type transthyretin amyloid cardiomyopathy.
Characterizing the High Disease Burden of Transthyretin Amyloidosis for Patients and Caregivers.
Circulating microRNAs Profile in Patients With Transthyretin Variant Amyloidosis.
Clinical characteristics and natural history of wild-type transthyretin amyloid cardiomyopathy in Japan.
Clinical characteristics and prognosis of Chinese patients with hereditary transthyretin amyloid cardiomyopathy.
Clinical comparison of V122I genotypic variant of transthyretin amyloid cardiomyopathy with wild-type and other hereditary variants: a systematic review.
Clinical features and survival in senile systemic amyloidosis: comparison to familial transthyretin cardiomyopathy.
Clinical Importance of Left Atrial Infiltration in Cardiac Transthyretin Amyloidosis.
Coexistent transthyretin amyloid cardiomyopathy and monoclonal gammopathy: Diagnostic challenges and prognostic implications.
Combined heart and liver transplantation for familial amyloidotic neuropathy: considerations from the hepatic point of view.
Combining ECG and echocardiography to identify transthyretin cardiac amyloidosis in heart failure.
Compassionate drug use for patients with transthyretin amyloid cardiomyopathy.
Contributions of Animal Models to the Mechanisms and Therapies of Transthyretin Amyloidosis.
Coronary ectasia in amyloid cardiomyopathy and neuropathy due to the transthyretin mutation c.323A>G.
Cost-Effectiveness of Tafamidis Therapy for Transthyretin Amyloid Cardiomyopathy.
Design and Rationale of the Phase 3 ATTR-ACT Clinical Trial (Tafamidis in Transthyretin Cardiomyopathy Clinical Trial).
Development of cardiomyopathy after liver transplantation in Swedish hereditary transthyretin amyloidosis (ATTR) patients.
Development of late amyloid cardiomyopathy following liver transplantation for hereditary Val30Met transthyretin amyloidosis.
Diagnosis of Transthyretin Amyloid Cardiomyopathy.
Diagnosis of wild-type transthyretin amyloid cardiomyopathy in Japan: red-flag symptom clusters and diagnostic algorithm.
Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis.
Diagnostic and lifetime hospital costs of patients suffering from wild-type transthyretin amyloid cardiomyopathy in Denmark.
Dietary curcumin counteracts extracellular transthyretin deposition: insights on the mechanism of amyloid inhibition.
Diflunisal tolerability in transthyretin cardiac amyloidosis: a single center's experience.
Diphosphonate single-photon emission computed tomography in cardiac transthyretin amyloidosis.
Diuretic Dose and NYHA Functional Class Are Independent Predictors of Mortality in Patients With Transthyretin Cardiac Amyloidosis.
Do troponin and B-natriuretic peptide detect cardiomyopathy in transthyretin amyloidosis?
Echocardiographic phenotype and prognosis in transthyretin cardiac amyloidosis.
Editorial Commentary: Advances in transthyretin amyloid cardiomyopathy.
Efficacy and safety of tafamidis doses in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and long-term extension study.
Efficacy of Tafamidis in Patients With Hereditary and Wild-Type Transthyretin Amyloid Cardiomyopathy: Further Analyses From ATTR-ACT.
Enthalpy-Driven Stabilization of Transthyretin by AG10 Mimics a Naturally Occurring Genetic Variant That Protects from Transthyretin Amyloidosis.
Establishment of an induced pluripotent stem cell line PUMCHi004-A from a hereditary transthyretin amyloid cardiomyopathy patient with transthyretin (TTR) p.Asp38Asn mutation.
Estimating the Gender Distribution of Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy: A Systematic Review and Meta-Analysis.
Estimating the health benefits of timely diagnosis and treatment of transthyretin amyloid cardiomyopathy.
Estimating the Prevalence of Transthyretin Amyloid Cardiomyopathy in a Large In-Hospital Database in Japan.
Etiology of Amyloidosis Determines Myocardial 99mTc-DPD Uptake in Amyloidotic Cardiomyopathy.
Evaluation of tafamidis as first-line therapeutic agent for transthyretin familial amyloidotic polyneuropathy.
Expert consensus on the monitoring of transthyretin amyloid cardiomyopathy.
Expert Consensus Recommendations for the Suspicion and Diagnosis of Transthyretin Cardiac Amyloidosis.
Extrapolation of Survival Benefits in Patients with Transthyretin Amyloid Cardiomyopathy Receiving Tafamidis: Analysis of the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial.
False-positive bone scintigraphy denoting transthyretin amyloid in elderly hypertrophic cardiomyopathy.
Familial amyloid polyneuropathy.
Familial wild-type transthyretin cardiomyopathy.
Fluorotryptophan incorporation modulates the structure and stability of transthyretin in a site-specific manner.
FRET studies of various conformational states adopted by transthyretin.
From Clinical Clues to Final Diagnosis: The Return of Detective Work to Clinical Medicine in Cardiac Amyloidosis.
Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis.
Glycosaminoglycans in extracts of cardiac amyloid fibrils from familial amyloid cardiomyopathy of Danish origin related to variant transthyretin Met 111.
Green tea extract as a treatment for patients with wild-type transthyretin amyloidosis: an observational study.
Green tea halts progression of cardiac transthyretin amyloidosis: an observational report.
Guideline of transthyretin-related hereditary amyloidosis for clinicians.
Health Impact of Tafamidis in Transthyretin Amyloid Cardiomyopathy patients: An Analysis from the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and the Open-Label Long-term Extension Studies.
Hereditary amyloidosis with cardiomyopathy caused by the novel variant transthyretin A36D.
Hereditary ATTR Amyloidosis with Cardiomyopathy Caused by the Novel Variant Transthyretin Y114S (p.Y134S).
Hereditary transthyretin amyloidosis caused by the rare Phe33Leu mutation.
Hereditary Transthyretin Amyloidosis: Clinical Presentation and Management Updates.
Identification of a novel TTR Gly67Glu mutant and the first case series of familial transthyretin amyloidosis in Hong Kong Chinese.
Imaging cardiac innervation in hereditary transthyretin (ATTRm) amyloidosis: A marker for neuropathy or cardiomyopathy in case of heart failure?
Imaging of cardiac amyloidosis by (99m)Tc-PYP scintigraphy.
Impact of Delayed Diagnosis and Misdiagnosis for Patients with Transthyretin Amyloid Cardiomyopathy (ATTR-CM): A Targeted Literature Review.
Impact of Tafamidis on Health-Related Quality of Life in Patients With Transthyretin Amyloid Cardiomyopathy (from the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial).
In brief: Tafamidis (Vyndaqel; Vyndamax) for transthyretin amyloid cardiomyopathy.
Inflammatory and Molecular Pathways in Heart Failure-Ischemia, HFpEF and Transthyretin Cardiac Amyloidosis.
Initial Experience With Tafamidis Treatment for Transthyretin Amyloid Cardiomyopathy.
Inotersen for the Treatment of Hereditary Transthyretin Amyloidosis.
Inotersen therapy of transthyretin amyloid cardiomyopathy.
Interatrial septal 99mTc-pyrophosphate uptake and reduced strain in wild-type transthyretin amyloid cardiomyopathy.
Involvement of human monogenic cardiomyopathy genes in experimental polygenic cardiac hypertrophy.
Isolated heart transplantation for familial transthyretin (TTR) V122I cardiac amyloidosis.
Kinetic analysis of the multistep aggregation pathway of human transthyretin.
Late-onset and fast progressive neuropathy and cardiomyopathy in Val32Ala transthyretin gene mutation.
Letter regarding the article 'Efficacy and safety of tafamidis doses in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and long-term extension study'.
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data.
Long-term outcome in patients treated with combined heart and liver transplantation for familial amyloidotic cardiomyopathy.
Markers of nutritional status and inflammation in transthyretin cardiac amyloidosis: association with outcomes and the clinical phenotype.
Matrix metalloproteinases and their tissue inhibitors in cardiac amyloidosis: relationship to structural, functional myocardial changes and to light chain amyloid deposition.
Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis.
Methods to evaluate the inhibition of TTR fibrillogenesis induced by small ligands.
Modeling of Survival and Frequency of Cardiovascular-Related Hospitalization in Patients with Transthyretin Amyloid Cardiomyopathy Treated with Tafamidis.
Molecular diagnosis of the transthyretin (TTR) Met111 mutation in familial amyloid cardiomyopathy of Danish origin.
Molecular dynamics simulation study of AG10 and tafamidis binding to the Val122Ile transthyretin variant.
Monitoring treatment response to tafamidis by serial native T1 and extracellular volume in transthyretin amyloid cardiomyopathy.
Multi-modality imaging in transthyretin amyloid cardiomyopathy.
Natural history and progression of transthyretin amyloid cardiomyopathy: insights from ATTR-ACT.
Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis.
Negative bone scintigraphy in wild-type transthyretin cardiac amyloidosis.
New pathological insights into cardiac amyloidosis: implications for non-invasive diagnosis.
Nonbiopsy Diagnosis of Cardiac Transthyretin Amyloidosis.
Noninvasive diagnosis of hereditary transthyretin-related cardiac amyloidosis: A case report.
Novel drugs targeting transthyretin amyloidosis.
Novel insights into rare cardiomyopathies: arrhythmogenic cardiomyopathy, non-compaction, and transthyretin amyloidosis.
Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management.
Orthotopic liver transplantation for familial amyloidotic polyneuropathy: a pathological study.
Outcome in patients treated with isolated liver transplantation for familial transthyretin amyloidosis to prevent cardiomyopathy.
Patient and family experience with transthyretin amyloid cardiomyopathy (ATTR-CM) and polyneuropathy (ATTR-PN) amyloidosis: results of two focus groups.
Patisiran, an RNAi therapeutic for the treatment of hereditary transthyretin-mediated amyloidosis.
Personalized medicine approach for optimizing the dose of tafamidis to potentially ameliorate wild-type transthyretin amyloidosis (cardiomyopathy).
Pharmacotherapy review: Emerging treatment modalities in transthyretin cardiac amyloidosis.
Phase 3 Multicenter Study of Revusiran in Patients with Hereditary Transthyretin-Mediated (hATTR) Amyloidosis with Cardiomyopathy (ENDEAVOUR).
Poor right ventricular function is associated with impaired exercise capacity and ventilatory efficiency in transthyretin cardiac amyloid patients.
Potent kinetic stabilizers that prevent transthyretin-mediated cardiomyocyte proteotoxicity.
Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions.
Prevalence and clinical phenotype of hereditary transthyretin amyloid cardiomyopathy in patients with increased left ventricular wall thickness.
Prevalence and Outcomes of p.Val142Ile TTR Amyloidosis Cardiomyopathy: A Systematic Review.
Prevalence and Prognostic Significance of Frailty Among Patients With Transthyretin Amyloidosis Cardiomyopathy.
Prevalence of Atrial Fibrillation and Thromboembolic Risk in Wild-Type Transthyretin Amyloid Cardiomyopathy.
Prevalence of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction.
Prevalence of transthyretin amyloid cardiomyopathy in male patients who underwent bilateral carpal tunnel surgery: The ACTUAL study.
Prevalence of TTR variants detected by whole-exome sequencing in hypertrophic cardiomyopathy.
Prevalence, Incidence, and Impact on Mortality of Conduction System Disease in Transthyretin Cardiac Amyloidosis.
Prognostic assessment of relative apical sparing pattern of longitudinal strain for severe aortic valve stenosis.
Prognostic Role of Cardiopulmonary Exercise Testing in Wild-Type Transthyretin Amyloid Cardiomyopathy Patients Treated With Tafamidis.
Progression of cardiomyopathy after liver transplantation in patients with familial amyloidotic polyneuropathy, Portuguese type.
Progression of cardiomyopathy and neuropathy after liver transplantation in a patient with familial amyloidotic polyneuropathy caused by tyrosine-77 transthyretin variant.
Prospective evaluation of the morbidity and mortality of wild-type and V122I mutant transthyretin amyloid cardiomyopathy: The Transthyretin Amyloidosis Cardiac Study (TRACS).
Psychosocial burden and professional and social support in patients with hereditary transthyretin amyloidosis (ATTRv) and their relatives in Italy.
Purification and characterization of amyloid-related transthyretin associated with familial amyloidotic cardiomyopathy.
Quaternary structure, aggregation and cytotoxicity of transthyretin.
Rate of progression of transthyretin amyloidosis.
Rational design of potent human transthyretin amyloid disease inhibitors.
Real-world versus trial patients with transthyretin amyloid cardiomyopathy.
Recent advances in the diagnosis and management of cardiac amyloidosis.
Recent advances in the treatment of chronic heart failure.
Recipe for Success in Transthyretin Cardiomyopathy: Monoclonal Protein Rule Out, SPECT Imaging, and Genetic Testing.
Reduced myocardial 123-iodine metaiodobenzylguanidine uptake: a prognostic marker in familial amyloid polyneuropathy.
Reduction in CMR Derived Extracellular Volume With Patisiran Indicates Cardiac Amyloid Regression.
Reply to the letter regarding the article 'Efficacy and safety of tafamidis doses in the Tafamidis in Transthyretin Cardiomyopathy Clinical Trial (ATTR-ACT) and long-term extension study'.
Reply: Bio-Profiling of Transthyretin Amyloid Cardiomyopathy.
Restrictive cardiac phenotype as primary cause of impaired aerobic capacity in Afro-Caribbean patients with val122ile variant transthyretin amyloid cardiomyopathy.
Retinal microangiopathy as an initial manifestation of familial amyloid cardiomyopathy associated with transthyretin e89k mutation.
Retrospective molecular detection of Transthyretin Met 111 mutation in a Danish kindred with familial amyloid cardiomyopathy, using DNA from formalin-fixed and paraffin-embedded tissues.
S-Homocysteinylation effects on transthyretin: worsening of cardiomyopathy onset.
Safety and efficacy of a TTR specific antisense oligonucleotide in patients with transthyretin amyloid cardiomyopathy.
Screening for Transthyretin Amyloid Cardiomyopathy in Everyday Practice.
Sex-Related Risk of Cardiac Involvement in Hereditary Transthyretin Amyloidosis: Insights From THAOS.
Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses.
Speckle Tracking and Transthyretin Amyloid Cardiomyopathy.
Spectrum of Restrictive and Infiltrative Cardiomyopathies: Part 1 of a 2-Part Series.
Sporadic Cardiac Amyloidosis by Amyloidogenic Transthyretin V122I Variant.
Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis.
Stabilizing Transthyretin to Treat ATTR Cardiomyopathy.
Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils.
Structure of the Val122Ile variant transthyretin - a cardiomyopathic mutant.
Structure-based analysis of A19D, a variant of transthyretin involved in familial amyloid cardiomyopathy.
Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides.
Synthesis and characterization of potent bivalent amyloidosis inhibitors that bind prior to transthyretin tetramerization.
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
Tafamidis (Vyndaqel; Vyndamax) for Transthyretin Amyloid Cardiomyopathy.
Tafamidis for the Treatment of Hereditary Transthyretin Amyloid Cardiomyopathy: A Case Report.
Tafamidis for Transthyretin Amyloid Cardiomyopathy.
Tafamidis for transthyretin amyloid cardiomyopathy: the solution or just the beginning of the end?
Tafamidis in transthyretin amyloid cardiomyopathy: effects on transthyretin stabilization and clinical outcomes.
Tafamidis Should Be Accessible for All Patients With Transthyretin Amyloid Cardiomyopathy.
Tafamidis Treatment for Patients with Transthyretin Amyloid Cardiomyopathy.
Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.
Tafamidis: A First-in-Class Transthyretin Stabilizer for Transthyretin Amyloid Cardiomyopathy.
Tafamidis: a novel treatment for transthyretin amyloid cardiomyopathy.
Tafamidis: A Review in Transthyretin Amyloid Cardiomyopathy.
Tafamidis: a selective transthyretin stabilizer to treat wild-type ATTR amyloidosis and hereditary ATTR amyloidosis with cardiomyopathy.
Tc-HDP quantitative SPECT/CT in transthyretin cardiac amyloid and the development of a reference interval for myocardial uptake in the non-affected population.
The "Wagshurst study": p.Val40Ile transthyretin gene variant causes late-onset cardiomyopathy.
The amyloidogenic V122I transthyretin variant in elderly black Americans.
The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin.
The flavonoid luteolin, but not luteolin-7-O-glucoside, prevents a transthyretin mediated toxic response.
The genetics of cardiac amyloidosis.
The polyphenol Oleuropein aglycone hinders the growth of toxic transthyretin amyloid assemblies.
The V122I cardiomyopathy variant of transthyretin increases the velocity of rate-limiting tetramer dissociation, resulting in accelerated amyloidosis.
Therapeutic Strategies Targeting Inherited Cardiomyopathies.
Therapy of Transthyretin Cardiomyopathy.
Three siblings of familial amyloid cardiomyopathy with isoleucine-50 transthyretin mutation.
Transthyretin Amyloid Cardiomyopathy Diagnosed on Incidental Myocardial Uptake During Bone Scintigraphy.
Transthyretin amyloid cardiomyopathy in women: frequency, characteristics, and diagnostic challenges.
Transthyretin Amyloid Cardiomyopathy Mimicking Hypertrophic Cardiomyopathy in an Older Patient.
Transthyretin Amyloid Cardiomyopathy-Current and Future Therapies.
Transthyretin amyloid cardiomyopathy.
Transthyretin amyloid cardiomyopathy: An uncharted territory awaiting discovery.
Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review.
Transthyretin amyloid cardiomyopathy: The emerging role of cardiac amyloid imaging.
Transthyretin amyloidosis with cardiomyopathy after domino liver transplantation: Results of a cross-sectional study.
Transthyretin amyloidosis: an under-recognized neuropathy and cardiomyopathy.
Transthyretin amyloidosis: Putting myopathy on the map.
Transthyretin Cardiac Amyloidosis and Novel Therapies to Treat This Not-so-rare Cause of Cardiomyopathy.
Transthyretin Cardiac Amyloidosis.
Transthyretin cardiac amyloidosis.
Transthyretin cardiac amyloidosis: A treatable form of heart failure with a preserved ejection fraction.
Transthyretin cardiac amyloidosis: an update on diagnosis and treatment.
Transthyretin Glu54Leu - an unknown mutation within the Swedish population associated with amyloid cardiomyopathy and a unique fibril type.
Transthyretin related familial amyloid polyneuropathy.
Transthyretin RNA profiling in livers from transplanted patients affected by familial amyloidotic polyneuropathy, and identification of a dual transcription start point.
Transthyretin Tyr69-to-Ile mutation (double-nucleotide substitution in codon 69) in a Japanese familial amyloidosis patient with cardiomyopathy and carpal tunnel syndrome.
Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly African Americans.
Transthyretin V122I amyloidosis with clinical and histological evidence of amyloid neuropathy and myopathy.
Treatment of hereditary and acquired forms of transthyretin amyloidosis in the era of personalized medicine: the role of randomized controlled trials.
Treatment of transthyretin cardiomyopathy with a TTR-specific antisense oligonucleotide (IONIS-TTRRx).
Treatment With Tafamidis Slows Disease Progression in Early-Stage Transthyretin Cardiomyopathy.
Two Siblings Diagnosed to Have Transthyretin-related Familial Amyloid Cardiomyopathy Around the Same Time at Different Hospitals.
Unmasking Early Wild-Type Transthyretin Amyloidosis Cardiomyopathy in a Patient With Refractory Atrial Fibrillation and Unremarkable Cardiac Imaging.
Updates in Cardiac Amyloidosis Diagnosis and Treatment.
Use of Ventilatory Efficiency Slope as a Marker for Increased Mortality in Wild-Type Transthyretin Cardiac Amyloidosis.
Usefulness of relative apical longitudinal strain index to predict positive 99m Tc-labeled pyrophosphate scintigraphy findings in advanced-age patients with suspected transthyretin amyloid cardiomyopathy.
V122I Transthyretin Cardiomyopathy: An Opportunity to Build Trust and Resolve Disparities.
Verification of the transthyretin Met 111 mutation in familial amyloid cardiomyopathy of Danish origin by DNA sequencing.
Wild type transthyretin cardiac amyloidosis in a young individual: A case report.
Wild-type transthyretin amyloid cardiomyopathy complicated by spinal canal stenosis, carpal tunnel syndrome, and rotator cuff tears: a case report.
Wild-Type Transthyretin Amyloid Cardiomyopathy: A Missed Cause of Heart Failure With Preserved Ejection Fraction With Evolving Treatment Implications.
Wild-type Transthyretin Amyloid Myopathy With an Inclusion Body Myositis Phenotype.
Yield of Noncardiac Biopsy for the Diagnosis of Transthyretin Cardiac Amyloidosis.
[Hereditary amyloid cardiomyopathy related to a mutation at transthyretin protein number 111. A clinical, genetic and echocardiographic study of an affected Danish family]
[Transthyretin amyloid cardiomyopathy].
[Transthyretin amyloidoses]
[Transthyretin gene V30M, H90N, and del9 mutations in cardiomyopathy patients from St. Petersburg].
Cardiomyopathy, Hypertrophic
Amyloid heart disease mimicking hypertrophic cardiomyopathy.
Can echocardiography and ECG discriminate hereditary transthyretin V30M amyloidosis from hypertrophic cardiomyopathy?
False-positive bone scintigraphy denoting transthyretin amyloid in elderly hypertrophic cardiomyopathy.
From hypertrophic cardiomyopathy to transthyretin amyloidosis: an unusual case and challenging diagnosis.
Hereditary transthyretin amyloidosis caused by the rare Phe33Leu mutation.
Left Atrial Morphology, Size and Function in Patients With Transthyretin Cardiac Amyloidosis and Primary Hypertrophic Cardiomyopathy?- Comparative Strain Imaging Study.
Transthyretin Amyloid Cardiomyopathy Mimicking Hypertrophic Cardiomyopathy in an Older Patient.
Transthyretin amyloidosis in a septuagenarian masquerading as hypertrophic cardiomyopathy: the importance of multimodality imaging.
Transthyretin Amyloidosis Mimicking Obstructive Hypertrophic Cardiomyopathy: A Great Imitator.
Transthyretin amyloidosis: a phenocopy of hypertrophic cardiomyopathy.
[Liver transplantation in familial amyloid polyneuropathy. Case report and review of the literature]
Cardiomyopathy, Restrictive
A clinical, echocardiographic and genetic characterization of a Danish kindred with familial amyloid transthyretin methionine 111 linked cardiomyopathy.
Cardiac amyloidosis associated with a novel transthyretin aspartic acid-18 glutamic acid de novo mutation.
Cardiac amyloidosis associated with the transthyretin Ile122 mutation in a Caucasian family.
Cardiac Amyloidosis: Evolving Diagnosis and Management: A Scientific Statement From the American Heart Association.
Demyelinating Neuropathy in a Patient Treated With Revusiran for Transthyretin (Thr60Ala) Amyloidosis.
Disease-Specific Biomarkers in Transthyretin Cardiac Amyloidosis.
Emerging Therapeutics for the Treatment of Light Chain and Transthyretin Amyloidosis.
Hereditary Amyloidosis with Recurrent Lung Infiltrates.
Hip and knee arthroplasty are common among patients with transthyretin cardiac amyloidosis, occurring years before cardiac amyloid diagnosis: can we identify affected patients earlier?
Myocardial Contraction Fraction by M-Mode Echocardiography Is Superior to Ejection Fraction in Predicting Mortality in Transthyretin Amyloidosis.
Novel drugs targeting transthyretin amyloidosis.
Senile cardiac amyloidosis associated with homozygosity for a transthyretin variant (ILE-122).
Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides.
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis.
Transthyretin Ile 122 and cardiac amyloidosis in African-Americans. 2 case reports.
Wild-type TTR amyloidosis among patients with unexplained heart failure and systolic LV dysfunction.
[Bone seeking tracers' scintigraphy for the diagnosis of transthyretin cardiac amyloidosis].
[Hereditary amyloid cardiomyopathy related to a mutation at transthyretin protein number 111. A clinical, genetic and echocardiographic study of an affected Danish family]
Cardiovascular Diseases
Acute Phase Reactants as Novel Predictors of Cardiovascular Disease.
Transthyretin: From Structural Stability to Osteoarticular and Cardiovascular Diseases.
Carpal Tunnel Syndrome
A case of unilateral shoulder joint hydrarthrosis with wild-type amyloidogenic transthyretin amyloidosis.
A case study of likely wild-type cardiac transthyretin amyloidosis causing rapid deterioration.
A new transthyretin variant (Glu61Gly) associated with cardiomyopathy.
A novel transthyretin Lys70Glu (p.Lys90Glu) mutation presenting with vitreous amyloidosis and carpal tunnel syndrome.
A transthyretin mutation (Tyr78Phe) associated with peripheral neuropathy, carpal tunnel syndrome and skin amyloidosis.
Amyloid and peripheral nervous system disease.
Cardiomyopathy in a Japanese family with the Glu61Lys transthyretin variant: a new phenotype.
Carpal tunnel syndrome and spinal canal stenosis: harbingers of transthyretin amyloid cardiomyopathy?
Carpal Tunnel Syndrome Due to Iatrogenic Amyloidosis After Domino Liver Transplantation From Hereditary Transthyretin Amyloidosis: A Case Report.
Carpal tunnel syndrome in cardiac amyloidosis: implications for early diagnosis and prognostic role across the spectrum of aetiologies.
Carpal Tunnel Syndrome in Transthyretin Cardiac Amyloidosis: Implications and Protocol for Diagnosis and Treatment.
Effect of synovial transthyretin amyloid deposition on preoperative symptoms and postoperative recovery of median nerve function among patients with idiopathic carpal tunnel syndrome.
Establishing and validating the fluorescent amyloid ligand h-FTAA (heptamer formyl thiophene acetic acid) to identify transthyretin amyloid deposits in carpal tunnel syndrome.
Familial amyloid polyneuropathy in a Spanish family with a transthyretin deletion (deltaVal 122) presenting with carpal tunnel syndrome.
Familial amyloidotic polyneuropathy presenting with carpal tunnel syndrome and a new transthyretin mutation, asparagine 70.
Familial carpal tunnel syndrome due to amyloidogenic transthyretin His 114 variant.
High prevalence of wild-type transthyretin deposition in patients with idiopathic carpal tunnel syndrome: a common cause of carpal tunnel syndrome in the elderly.
New mutant gene (transthyretin Arg 58) in cases with hereditary polyneuropathy detected by non-isotope method of single-strand conformation polymorphism analysis.
Nodular cutaneous amyloidosis and carpal tunnel syndrome due to the amyloidogenic transthyretin His 114 variant.
Non-senile wild-type transthyretin systemic amyloidosis presenting as bilateral carpal tunnel syndrome.
Prevalence and clinical phenotype of hereditary transthyretin amyloid cardiomyopathy in patients with increased left ventricular wall thickness.
Prevalence of transthyretin amyloid cardiomyopathy in male patients who underwent bilateral carpal tunnel surgery: The ACTUAL study.
Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses.
The significance of carpal tunnel syndrome in transthyretin Val30Met familial amyloid polyneuropathy.
The Tenosynovitis of Fingers Associated with Transthyretin Amyloidosis.
Transthyretin Tyr69-to-Ile mutation (double-nucleotide substitution in codon 69) in a Japanese familial amyloidosis patient with cardiomyopathy and carpal tunnel syndrome.
Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy.
Where Neurosurgery Meets Heart Failure: A Case Report of a Patient with Amyloid Transthyretin Wild Type in the Ligamentum Flavum and Cardiac Tissue with Bilateral Carpal Tunnel Syndrome.
Wild-type transthyretin amyloid cardiomyopathy complicated by spinal canal stenosis, carpal tunnel syndrome, and rotator cuff tears: a case report.
Wild-type Transthyretin Amyloid Myopathy With an Inclusion Body Myositis Phenotype.
[Carpal tunnel syndrome and ATTR-amyloidosis].
Cataract
Albumin and transthyretin as risk factors for cataract: the POLA study.
Identification of vitreous proteins in retinopathy of prematurity.
Celiac Disease
Transthyretin: a marker for celiac disease activity.
Cerebral Amyloid Angiopathy
Characterization of a transthyretin-related amyloid fibril protein from cerebral amyloid angiopathy in type I familial amyloid polyneuropathy.
Clinical aspects of cerebral amyloid angiopathy.
Coexistence of transthyretin- and A?-type cerebral amyloid angiopathy in a patient with hereditary transthyretin V30M amyloidosis.
Comparison of clinical features in transient focal neurological episodes between hereditary transthyretin type and A? type cerebral amyloid angiopathy.
Effect of liver transplantation on transthyretin Tyr114Cys-related cerebral amyloid angiopathy.
Recurrent subarachnoid bleeding and superficial siderosis in a patient with histopathologically proven cerebral amyloid angiopathy.
[Cerebral amyloid angiopathies]
[Cerebral amyloid angiopathy]
[Hereditary cerebral amyloid angiopathies]
Cerebral Amyloid Angiopathy, Familial
Effect of liver transplantation on transthyretin Tyr114Cys-related cerebral amyloid angiopathy.
Cerebral Hemorrhage
Effect of liver transplantation on transthyretin Tyr114Cys-related cerebral amyloid angiopathy.
Protein aging Extracellular amyloid formation and intracellular repair.
Cerebrospinal Fluid Rhinorrhea
Microfluidic validation of diagnostic protein markers for spontaneous cerebrospinal fluid rhinorrhea.
Cerebrovascular Disorders
Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy.
ProApolipoprotein A1: a serum marker of brain metastases in lung cancer patients.
Charcot-Marie-Tooth Disease
Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis.
The Italian neuromuscular registry: a coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage.
[What's new in hereditary neuropathies ?].
Cholangiocarcinoma
Serum levels of variants of transthyretin down-regulation in cholangiocarcinoma.
Cholangitis
EUS-guided Biliary Drainage for Malignant Perihilar Biliary Strictures after Further Transpapillary Intervention Has Been Judged to Be Impossible or Ineffective.
Cholangitis, Sclerosing
Systemic but asymptomatic transthyretin amyloidosis 8 years after domino liver transplantation.
Cholestasis
Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer.
Impaired synthesis of retinol-binding protein and transthyretin in rat liver with bile duct obstruction.
Choriocarcinoma
CARRIER MEDIATED THYROID HORMONE TRANSPORT INTO PLACENTA BY PLACENTAL TRANSTHYRETIN.
Oxygen concentration regulates expression and uptake of transthyretin, a thyroxine binding protein, in JEG-3 choriocarcinoma cells.
Choroid Plexus Neoplasms
Choroid plexus papilloma with stromal deposition of amyloid and elastic material.
Choroid plexus tumors in childhood. Histopathologic study and clinico-pathological correlation.
Clinicopathologic correlations in epithelial choroid plexus neoplasms: a study of 52 cases.
Transthyretin expression in medulloblastomas and medulloblastoma cell lines.
Transthyretin immunoreactivity in choroid plexus neoplasms and brain metastases.
Choroidal Neovascularization
Choroidal Neovascularization in Familial Transthyretin Amyloidosis.
Colorectal Neoplasms
Biomarkers for the early detection of relapses in metastatic colorectal cancers.
Detection of colorectal adenoma and cancer based on transthyretin and C3a-desArg serum levels.
Immunohistochemical Assessment of Transthyretin Association with Colorectal Adenocarcinoma.
Coma
Impact of a High-protein Nutritional Intake on the Clinical Outcome of the Neurocritical Patients.
Confusion
Systemic AL amyloidosis with unusual cutaneous presentation unmasked by carotenoderma.
Transthyretin for the routine assessment of malnutrition: A clinical dilemma highlighted by an international survey of experts in the field.
Congenital Abnormalities
Naso-maxillary deformity due to frontonasal expression of human transthyretin gene in transgenic mice.
Corneal Dystrophies, Hereditary
Amyloidosis and Ocular Involvement: an Overview.
Coronary Artery Disease
Changes in the proteomic profile of blood serum in coronary atherosclerosis.
Cough
Familial amyloid polyneuropathy with chronic paroxysmal dry cough in Mainland China: A Chinese family with a proven heterozygous missense mutation c.349G>T in the transthyretin gene.
COVID-19
ATTR amyloidosis during the COVID-19 pandemic: insights from a global medical roundtable.
Cranial Nerve Diseases
Amyloid fibril protein in familial amyloidosis with cranial neuropathy and corneal lattice dystrophy (FAP type IV) is related to transthyretin.
CREST Syndrome
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity.
Creutzfeldt-Jakob Syndrome
Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of De Novo generation of Creutzfeldt-Jakob disease infectious amyloid by a spontaneous change in configuration of the host precursor protein.
Crohn Disease
Immune activation and nutritional status in adult Crohn's disease patients.
Cystic Fibrosis
Involvement of hepatocyte nuclear factor 3 in endoderm differentiation of embryonic stem cells.
Deglutition Disorders
Cognitive Dysfunction and Malnutrition Are Independent Predictor of Dysphagia in Patients with Acute Exacerbation of Congestive Heart Failure.
Dementia
A novel amyloidogenic transthyretin variant, Gly53Ala, associated with intermittent headaches and ataxia.
Effect of liver transplantation on transthyretin Tyr114Cys-related cerebral amyloid angiopathy.
Effects of Chronic Stress on Prefrontal Cortex Transcriptome in Mice Displaying Different Genetic Backgrounds.
Inflammation and disability as risk factors for mortality in elderly acute care patients.
Molecular biology of brain aging and neurodegenerative disorders.
Plasma Transthyretin as a Predictor of Amnestic Mild Cognitive Impairment Conversion to Dementia.
Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia.
Recurrent subarachnoid hemorrhage associated with a new transthyretin variant (Gly53Glu).
Serum and cerebrospinal fluid levels of transthyretin in Lewy body disorders with and without dementia.
Serum transthyretin and risk of cognitive decline and dementia: 22-year longitudinal study.
Transthyretin amyloidosis: a new mutation associated with dementia.
Transthyretin as a potential CSF biomarker for Alzheimer's disease and dementia with Lewy bodies: effects of treatment with cholinesterase inhibitors.
[An immunocytochemical study of alpha 1-antichymotrypsin in the senescent cerebral amyloid]
Demyelinating Diseases
Transthyretin amyloidosis presenting with multifocal demyelinating mononeuropathies.
Dengue
Two-dimensional difference gel electrophoresis (DiGE) analysis of plasmas from dengue fever patients.
Diabetes Complications
Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.
Diabetes Mellitus
ALTERED CIRCULATING LEVELS OF RETINOL BINDING PROTEIN 4 AND TRANSTHYRETIN IN RELATION TO INSULIN RESISTANCE, OBESITY, AND GLUCOSE INTOLERANCE IN ASIAN INDIANS.
Association of retinol binding protein 4 and transthyretin with triglyceride levels and insulin resistance in rural thais with high type 2 diabetes risk.
Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology.
Creatinine index and transthyretin as additive predictors of mortality in haemodialysis patients.
Cysteinylated transthyretin as a discriminator of cardiovascular risk in patients with diabetes mellitus.
Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.
Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization.
Streptozotocin-induced diabetes lowers retinol-binding protein and transthyretin concentrations in rats.
Vitamin A homeostasis and diabetes mellitus.
Diabetes Mellitus, Type 1
Contrasting effects of type 2 and type 1 diabetes on plasma RBP4 levels: the significance of transthyretin.
Effect of metabolic control on serum protein concentrations in diabetes.
High-normal C-reactive protein levels do not affect the vitamin A transport complex in serum of children and adolescents with type 1 diabetes.
Sardinian Type 1 diabetes patients, Transthyretin and Mycobacterium avium subspecies paratuberculosis infection.
Diabetes Mellitus, Type 2
ALTERED CIRCULATING LEVELS OF RETINOL BINDING PROTEIN 4 AND TRANSTHYRETIN IN RELATION TO INSULIN RESISTANCE, OBESITY, AND GLUCOSE INTOLERANCE IN ASIAN INDIANS.
Association of retinol binding protein 4 and transthyretin with triglyceride levels and insulin resistance in rural thais with high type 2 diabetes risk.
Can complement factors 5 and 8 and transthyretin be used as biomarkers for MODY 1 (HNF4A-MODY) and MODY 3 (HNF1A-MODY)?
CCS/CHFS Heart Failure Guidelines: Clinical Trial Update on Functional Mitral Regurgitation, SGLT2 Inhibitors, ARNI in HFpEF, and Tafamidis in Amyloidosis.
Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology.
High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus.
Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.
Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization.
Transthyretin Predicts Cardiovascular Outcome in Hemodialysis Patients With Type 2 Diabetes.
Vitamin A homeostasis and diabetes mellitus.
[Biochemical studies of amyloidogenesis in two different types of amyloidoses--amyloid transthyretin variant in familial amyloidotic polyneuropathy and islet amyloid polypeptide in non-insulin-dependent diabetes mellitus]
Diabetes, Gestational
Association between transthyretin concentrations and gestational diabetes mellitus in Chinese women.
Maternal Circulating Transthyretin Level Is Longitudinally Associated With Increased Risk of Gestational Diabetes Mellitus: It Is Not Just an Indicator of Nutritional Status.
Serum concentrations of retinol-binding protein 4 in women with and without gestational diabetes.
Diabetic Nephropathies
[Effective usage of nutrition assessment proteins in patients with diabetic nephropathy]
Diabetic Neuropathies
Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy.
Diabetic Retinopathy
Negative effects of transthyretin in high myopic vitreous on diabetic retinopathy.
Repression of retinal microvascular endothelial cells by transthyretin under simulated diabetic retinopathy conditions.
Transcriptome analysis identified a novel 3-LncRNA regulatory network of transthyretin attenuating glucose induced hRECs dysfunction in diabetic retinopathy.
Transthyretin affects the proliferation and migration of human retinal microvascular endothelial cells in hyperglycemia via hnRNPA2B1.
Transthyretin Exerts Pro-Apoptotic Effects in Human Retinal Microvascular Endothelial Cells Through a GRP78-Dependent Pathway in Diabetic Retinopathy.
Transthyretin represses neovascularization in diabetic retinopathy.
Transthyretin Upregulates Long Non-Coding RNA MEG3 by Affecting PABPC1 in Diabetic Retinopathy.
Down Syndrome
Are Serum Protein Biomarkers Derived from Proteomic Analysis Useful in Screening for Trisomy 21 at 11-13 Weeks?
[Transthyretin levels in serum and cerebrospinal fluid sustain the nutrio-viral hypothesis of the Cuban epidemic neuropathy]
Dysautonomia, Familial
[Autonomic peripheral neuropathy].
Dysentery, Bacillary
Predictors of serum retinol in children with shigellosis.
Ecchymosis
Periorbital ecchymosis and shoulder pad sign in transthyretin amyloidosis.
Embolic Stroke
Stroke risk and atrial mechanical dysfunction in cardiac amyloidosis.
Ependymoma
Receptor-mediated endocytosis of transthyretin by ependymoma cells.
[Immunohistochemical study for choroid plexus papillomas and ependymomas]
Erectile Dysfunction
Effect of sildenafil citrate (Viagra) on erectile dysfunction in a patient with familial amyloidotic polyneuropathy ATTR Val30Met.
Exanthema
Vitamin a supplementation of vitamin a deficient measles patients lowers the risk of measles-related pneumonia in zambian children.
Fabry Disease
A prospective, observational study of patients with uncommon distal symmetric painful small-fiber neuropathy.
Charcot-Marie-Tooth Disease and Other Hereditary Neuropathies.
Diagnosis of small fiber neuropathy: A comparative study of five neurophysiological tests.
Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review.
Small fiber neuropathy: Diagnosis, causes, and treatment.
Fasciculation
Tongue atrophy and fasciculations in transthyretin familial amyloid neuropathy: An ALS mimicker.
Fatty Liver
Transthyretin Regulated by linc00657/miR-205-5p Promoted Cholesterol Metabolism by Inducing SREBP2-HMGCR and Inhibiting LXR?-CYP7A1.
Fetal Growth Retardation
Human placental transthyretin in fetal growth restriction in combination with preeclampsia and the HELLP syndrome.
Frontotemporal Dementia
Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia.
Ganglion Cysts
[An immunocytochemical study of alpha 1-antichymotrypsin in the senescent cerebral amyloid]
Gastrointestinal Diseases
Transthyretin Val122Ile amyloidosis associated with isolated gastrointestinal disease and bowel rupture in a Caucasian woman.
Gastrointestinal Neoplasms
Prognostic Value of Pretreatment Serum Transthyretin Level in Patients with Gastrointestinal Cancers.
Gastroparesis
Gastric peroral endoscopic myotomy for transthyretin amyloidosis gastroparesis.
Genetic Diseases, Inborn
Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis.
Bilateral optic neuropathy in a patient with familial amyloidotic polyneuropathy.
Characterization of population genetic structure of hereditary transthyretin amyloidosis in Bulgaria.
Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy.
Curcumin: A multi-target disease-modifying agent for late-stage transthyretin amyloidosis.
Erythropoietin production by distal nephron in normal and familial amyloidotic adult human kidneys.
Founder effect of the Glu89Gln TTR mutation in the Bulgarian population.
Gene expression profile in hereditary transthyretin amyloidosis: differences in targeted and source organs.
Genetic analysis of familial amyloidotic polyneuropathy, an autosomal dominant disease.
Glial cells in familial amyloidotic polyneuropathy.
Impact of Non-Cardiac Clinicopathologic Characteristics on Survival in Transthyretin Amyloid Polyneuropathy.
Inflammatory profiling of patients with familial amyloid polyneuropathy.
Molecular Tweezers Targeting Transthyretin Amyloidosis.
Novel drugs targeting transthyretin amyloidosis.
Population diversity of the genetically determined TTR expression in human tissues and its implications in TTR amyloidosis.
Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.
Somatostatin analogues for refractory diarrhoea in familial amyloid polyneuropathy.
Targeted suppression of an amyloidogenic transthyretin with antisense oligonucleotides.
The crystal structure of the green tea polyphenol (-)-epigallocatechin gallate-transthyretin complex reveals a novel binding site distinct from the thyroxine binding site.
The electrocardiographic features associated with cardiac amyloidosis of variant transthyretin isoleucine 122 type in Afro-Caribbean patients.
Update in the diagnosis and management of transthyretin familial amyloid polyneuropathy.
[Experience with tafamidis in a patient with transthyretin amyloidosis].
[Hereditary amyloidosis]
Giant Cell Arteritis
Transthyretin amyloidosis and herpes zoster infection: a mimic of temporal arteritis.
Glaucoma
A new transthyretin variant Leu55Gln in a patient with systemic amyloidosis.
Ahmed valve for secondary glaucoma in patients with hereditary transthyretin amyloidosis.
Baerveldt glaucoma drainage implant surgery for secondary glaucoma in patients with transthyretin-related familial amyloid polyneuropathy.
Excisional goniotomy with Kahook Dual Blade in a patient with glaucoma secondary to Transthyretin Amyloidosis.
Long-term outcomes and complications of trabeculectomy for secondary glaucoma in patients with familial amyloidotic polyneuropathy.
Secondary glaucoma in patients with familial amyloidotic polyneuropathy.
Small gauge vitrectomy for vitreous amyloidosis and subsequent management of secondary glaucoma in patients with hereditary transthyretin amyloidosis.
Systemic Alterations of Immune Response-Related Proteins during Glaucoma Development in the Murine Model DBA/2J.
Transthyretin and complex protein pattern in aqueous humor of patients with primary open-angle glaucoma.
Glaucoma, Neovascular
The use of intravitreal ranibizumab to treat neovascular glaucoma because of retinal amyloid angiopathy in familial amyloidosis transthyretin v30m related.
Glaucoma, Open-Angle
Transthyretin and complex protein pattern in aqueous humor of patients with primary open-angle glaucoma.
Glioma
Investigation of serum proteome alterations in human glioblastoma multiforme.
Multi-pronged proteomic analysis to study the glioma pathobiology using cerebrospinal fluid samples.
Transthyretin expression in medulloblastomas and medulloblastoma cell lines.
Glucose Intolerance
ALTERED CIRCULATING LEVELS OF RETINOL BINDING PROTEIN 4 AND TRANSTHYRETIN IN RELATION TO INSULIN RESISTANCE, OBESITY, AND GLUCOSE INTOLERANCE IN ASIAN INDIANS.
High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus.
Plasma Protein Biomarkers Correlated with the Development of Diet-Induced Type 2 Diabetes in Mice.
Glycogen Storage Disease Type II
Pompe Disease Could Mimic Exam Findings of Amyloidosis: Two Rare Diagnoses Bona Fide.
Goiter
Transthyretin Amyloid Goiter in a Renal Allograft Recipient.
Guillain-Barre Syndrome
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Hearing Loss
Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy.
Hearing Loss, Sensorineural
How your ears can tell what is hidden in your heart: wild-type transthyretin amyloidosis as potential cause of sensorineural hearing loss inelderly-AmyloDEAFNESS pilot study.
Heart Block
[Liver transplantation in familial amyloid polyneuropathy. Case report and review of the literature]
Heart Diseases
Cardiac amyloid imaging with 18F-florbetaben positron emission tomography: a pilot study.
Expert consensus on the monitoring of transthyretin amyloid cardiomyopathy.
Exploring the influence of mutation on transthyretin aggregation in heart disease.
Homozygous transthyretin mutation in an African American Male.
How to Image Cardiac Amyloidosis: A Practical Approach.
Renal Infarction and Its Consequences for Renal Function in Patients With Cardiac Amyloidosis.
Transthyretin Cardiac Amyloidosis in Black Americans.
Transthyretin Cardiac Amyloidosis.
Transthyretin V122I (pV142I)* cardiac amyloidosis: an age-dependent autosomal dominant cardiomyopathy too common to be overlooked as a cause of significant heart disease in elderly African Americans.
Variant-sequence transthyretin (isoleucine 122) in late-onset cardiac amyloidosis in black Americans.
[Transthyretin familial amyloid polyneuropathy - three Hungarian cases with rare mutations (His88Arg and Phe33Leu)].
Heart Failure
2021 Advocacy Statements for the Role of 99mTc-Pyrophosphate Scintigraphy in the Diagnosis of Transthyretin Cardiac Amyloidosis: A Report of the Taiwan Society of Cardiology and the Society of Nuclear Medicine of the Republic of China.
A case study of likely wild-type cardiac transthyretin amyloidosis causing rapid deterioration.
A Heart too Stiff to Beat: A Case of Familial Transthyretin Amyloidosis Cardiomyopathy.
A human antibody selective for transthyretin amyloid removes cardiac amyloid through phagocytic immune cells.
A machine learning model for identifying patients at risk for wild-type transthyretin amyloid cardiomyopathy.
A Patient With Hereditary ATTR and a Novel AGel p.Ala578Pro Amyloidosis.
A study of the neuropathy associated with transthyretin amyloidosis (ATTR) in the UK.
A transthyretin variant, Asp18Asn, associated with amyloid cardiomyopathy: a new African-American variant?
Acute cardiac failure secondary to senile systemic amyloidosis.
AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin.
An Italian family with Ala-47 transthyretin mutation associated with cardiomyopathy and polyneuropathy.
Assessment of Transthyretin Combined With Mini Nutritional Assessment on Admission Provides Useful Prognostic Information in Patients With Acute Decompensated Heart Failure.
Association of Carpal Tunnel Syndrome With Amyloidosis, Heart Failure, and Adverse Cardiovascular Outcomes.
Association of Low Plasma Transthyretin Concentration With Risk of Heart Failure in the General Population.
Association of the V122I Hereditary Transthyretin Amyloidosis Genetic Variant With Heart Failure Among Individuals of African or Hispanic/Latino Ancestry.
Association of the V122I Transthyretin Amyloidosis Genetic Variant With Cardiac Structure and Function in Middle-aged Black Adults: Coronary Artery Risk Development in Young Adults (CARDIA) Study.
Beneficial Effect of Pimobendan for Severe Heart Failure Due to Transthyretin Cardiac Amyloidosis.
Best Practices for Prognostic Evaluation of a Patient With Transthyretin Amyloid Cardiomyopathy.
Cardiac amyloidosis: An underdiagnosed/underappreciated disease.
Clinical Phenotyping of Transthyretin Cardiac Amyloidosis with Bone-Seeking Radiotracers in Heart Failure with Preserved Ejection Fraction.
Combining ECG and echocardiography to identify transthyretin cardiac amyloidosis in heart failure.
Cost-Effectiveness of Tafamidis Therapy for Transthyretin Amyloid Cardiomyopathy.
Deleterious effect of right ventricular pacing in patients with cardiac transthyretin amyloidosis: potential clinical benefit of cardiac resynchronization therapy.
Diagnosis and treatment of heart failure in hereditary transthyretin amyloidosis.
Diagnosis of Transthyretin Amyloid Cardiomyopathy.
Diflunisal for ATTR Cardiac Amyloidosis.
Echocardiographic phenotype and prognosis in transthyretin cardiac amyloidosis.
Elevated interleukin-6 levels are associated with impaired outcome in cardiac transthyretin amyloidosis.
Estimating cancer risk from 99mTc pyrophosphate imaging for transthyretin cardiac amyloidosis.
Features of atrial fibrillation in wild-type transthyretin cardiac amyloidosis: a systematic review and clinical experience.
Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt).
Genomic Screening Identifies Individuals at High Risk for Hereditary Transthyretin Amyloidosis.
Heart failure and cardiac involvement as isolated manifestation of familial form of transthyretin amyloidosis resulting from Val30Met mutation with no clinical signs of polyneuropathy.
Heart failure caused by a novel amyloidogenic mutation of the transthyretin gene: ATTR Ala45Ser.
Heart Failure Complicated by Alveolar Hemorrhage due to Vascular Collapse and Amyloid Deposits in Wild-Type Transthyretin Amyloidosis.
Heart Failure Resulting From Age-Related Cardiac Amyloid Disease Associated With Wild-Type Transthyretin: A Prospective, Observational Cohort Study.
Hereditary Amyloidosis with Recurrent Lung Infiltrates.
High prevalence of heart failure with reduced ejection fraction in patients with transthyretin cardiac amyloidosis.
How to Identify Transthyretin Cardiac Amyloidosis at an Early Stage.
Identification of Transthyretin Cardiac Amyloidosis Using Serum Retinol-Binding Protein 4 and a Clinical Prediction Model.
Inflammatory and Molecular Pathways in Heart Failure-Ischemia, HFpEF and Transthyretin Cardiac Amyloidosis.
Inotersen therapy of transthyretin amyloid cardiomyopathy.
Isolated heart transplantation for familial transthyretin (TTR) V122I cardiac amyloidosis.
Left atrial structure and function of the amyloidogenic V122I transthyretin variant in elderly African Americans.
Magnetic Resonance in Transthyretin Cardiac Amyloidosis.
Mechanisms of heart failure in transthyretin vs. light chain amyloidosis.
Misfolded Transthyretin as a Novel Risk Factor for Heart Failure: A Rich History With Implications for Future Diagnosis and Treatment.
Multicenter Study of Planar Technetium 99m Pyrophosphate Cardiac Imaging: Predicting Survival for Patients With ATTR Cardiac Amyloidosis.
Myocardial Contraction Fraction by M-Mode Echocardiography Is Superior to Ejection Fraction in Predicting Mortality in Transthyretin Amyloidosis.
Natural History of Wild-Type Transthyretin Cardiac Amyloidosis and Risk Stratification Using a Novel Staging System.
Natural History, Quality of Life, and Outcome in Cardiac Transthyretin Amyloidosis.
Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management.
Outcomes After Cardiac Transplant for Wild Type Transthyretin Amyloidosis.
Parenteral nutrition improves nutritional status, autonomic symptoms and quality of life in transthyretin amyloid polyneuropathy.
Patients with cardiac amyloidosis have a greater neurohormonal activation than those with non-amyloidotic heart failure.
Patisiran for advanced heart failure with hereditary transthyretin cardiac amyloidosis.
Phenotypic profile of Ile68Leu transthyretin amyloidosis: an underdiagnosed cause of heart failure.
Postmortem findings in two familial amyloidosis patients with transthyretin variant Asp38Ala.
Prevalence of Transthyretin Amyloid Cardiomyopathy in Heart Failure With Preserved Ejection Fraction.
Prevalence of transthyretin amyloidosis in patients with heart failure and no left ventricular hypertrophy.
Protein aging Extracellular amyloid formation and intracellular repair.
Rapid decline in ejection fraction and persistent elevation of troponin associated with cardiac amyloidosis.
Recent advances in the treatment of chronic heart failure.
Screening for Transthyretin Amyloid Cardiomyopathy in Everyday Practice.
Sex Differences in the Phenotype of Transthyretin Cardiac Amyloidosis Due to Val122Ile Mutation: Insights from Noninvasive Pressure-Volume Analysis.
Stabilization of Cardiac Function With Diflunisal in Transthyretin (ATTR) Cardiac Amyloidosis.
Standard heart failure medication in cardiac transthyretin amyloidosis: useful or harmful?
Structure of the Val122Ile variant transthyretin - a cardiomyopathic mutant.
Tafamidis: A First-in-Class Transthyretin Stabilizer for Transthyretin Amyloid Cardiomyopathy.
The amyloidogenic V122I transthyretin variant in elderly black Americans.
The electrocardiographic features associated with cardiac amyloidosis of variant transthyretin isoleucine 122 type in Afro-Caribbean patients.
The quintessential form of diastolic heart failure in older adults: Wild type transthyretin cardiac amyloidosis.
The Structural Understanding of Transthyretin Misfolding and the Inspired Drug Approaches for the Treatment of Heart Failure Associated With Transthyretin Amyloidosis.
Trajectory of left ventricular geometry and diastolic dysfunction in hereditary transthyretin cardiac amyloidosis.
Transthyretin amyloid cardiomyopathy in women: frequency, characteristics, and diagnostic challenges.
Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review.
Transthyretin amyloid fibrils alter primary fibroblast structure, function, and inflammatory gene expression.
Transthyretin amyloidosis in patients with undifferentiated heart failure.
Transthyretin Cardiac Amyloidosis as Diagnosed by 99mTc-PYP Scanning in Patients with Acute Heart Failure and Preserved Ejection Fraction.
Transthyretin cardiac amyloidosis in aortic stenosis: Prevalence, diagnostic challenges, and clinical implications.
Transthyretin Cardiac Amyloidosis in Older Adults: Optimizing Cardiac Imaging to the Corresponding Diagnostic and Management Goal.
Transthyretin Cardiac Amyloidosis in the Elderly-Tip of a Heart Failure Iceberg?
Transthyretin cardiac amyloidosis.
Transthyretin cardiac amyloidosis: A treatable form of heart failure with a preserved ejection fraction.
Transthyretin cardiac amyloidosis: an under-diagnosed cause of heart failure.
Transthyretin cardiac amyloidosis: pathogenesis, treatments, and emerging role in heart failure with preserved ejection fraction.
Transthyretin V122I in African Americans with congestive heart failure.
Unveiling wild-type transthyretin cardiac amyloidosis as a significant and potentially modifiable cause of heart failure with preserved ejection fraction.
Update in recent clinical trials in heart failure.
Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin.
Use of Ventilatory Efficiency Slope as a Marker for Increased Mortality in Wild-Type Transthyretin Cardiac Amyloidosis.
Usefulness of electron microscopy in the diagnosis of wild-type transthyretin cardiac amyloidosis.
Utility of 99 mTc-Pyrophosphate Scintigraphy in Diagnosing Transthyretin Cardiac Amyloidosis in Real-World Practice.
Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients.
Where Neurosurgery Meets Heart Failure: A Case Report of a Patient with Amyloid Transthyretin Wild Type in the Ligamentum Flavum and Cardiac Tissue with Bilateral Carpal Tunnel Syndrome.
Wild type transthyretin amyloidosis, a reason not to be forgotten for heart failure of preserved ejection fraction in the elderly.
Wild-Type Transthyretin Amyloid Cardiomyopathy: A Missed Cause of Heart Failure With Preserved Ejection Fraction With Evolving Treatment Implications.
Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction.
Wild-type TTR amyloidosis among patients with unexplained heart failure and systolic LV dysfunction.
[18F]-NaF PET/CT imaging in cardiac amyloidosis.
[Bone seeking tracers' scintigraphy for the diagnosis of transthyretin cardiac amyloidosis].
[Suspected cardiac amyloidosis - diagnostic steps for evaluation].
[Transthyretin amyloid cardiomyopathy].
Heart Failure, Diastolic
Cardiac transthyretin amyloidosis.
The quintessential form of diastolic heart failure in older adults: Wild type transthyretin cardiac amyloidosis.
Heart Failure, Systolic
Plasma hepatocyte growth factor is a novel marker of AL cardiac amyloidosis.
HELLP Syndrome
Human placental transthyretin in fetal growth restriction in combination with preeclampsia and the HELLP syndrome.
Hemangioblastoma
Transthyretin and transferrin in hemangioblastoma stromal cells.
Hematuria
Gross hematuria: An unusual presenting symptom of systemic wild-type transthyretinamyloidosis.
Hemoglobinopathies
Top-Down Analysis of Small Plasma Proteins Using an LTQ-Orbitrap. Potential for Mass Spectrometry-Based Clinical Assays for Transthyretin and Hemoglobin.
Hepatitis B
Characterization of liver specific promoters in a foamy viral vector pMD09.
Hepatitis C
Multimodality Imaging of Cardiac Transthyretin Amyloidosis 16 years after a Domino Liver Transplantation.
Hepatitis E
Plasma and urine biomarkers in acute viral hepatitis E.
Hepatomegaly
Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
Heredodegenerative Disorders, Nervous System
The impact of V30A mutation on transthyretin protein structural stability and cytotoxicity against neuroblastoma cells.
Hernias, Diaphragmatic, Congenital
Nitrofen interferes with trophoblastic expression of retinol-binding protein and transthyretin during lung morphogenesis in the nitrofen-induced congenital diaphragmatic hernia model.
Herpes Simplex
Gene targeting by a vector with hairpin-shaped oligonucleotide caps.
Structures of replacement vectors for efficient gene targeting.
Herpes Zoster
Transthyretin amyloidosis and herpes zoster infection: a mimic of temporal arteritis.
HIV Infections
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB.
Longitudinal evaluation of markers of inflammation in HIV-positive and HIV-negative Rwandan women.
Huntington Disease
Twenty Years of a Pre-Symptomatic Testing Protocol for Late-Onset Neurological Diseases in Portugal.
Hydrarthrosis
A case of unilateral shoulder joint hydrarthrosis with wild-type amyloidogenic transthyretin amyloidosis.
Hydrocephalus
Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia.
The Expression of Transthyretin and Amyloid-? Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.
[Case report of transthyretin Val30Met familial amyloid polyneuropathy presenting hydrocephalus].
Hydrocephalus, Normal Pressure
Quantitative analysis of transthyretin, tau and amyloid-beta in patients with dementia.
The Expression of Transthyretin and Amyloid-? Protein Precursor is Altered in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.
Hypercholesterolemia
Differential proteomic distribution of TTR (pre-albumin) forms in serum and HDL of patients with high cardiovascular risk.
Hyperglycemia
A novel transthyretin/STAT4/miR-223-3p/FBXW7 signaling pathway affects neovascularization in diabetic retinopathy.
Transthyretin affects the proliferation and migration of human retinal microvascular endothelial cells in hyperglycemia via hnRNPA2B1.
Hyperhomocysteinemia
S-homocysteinylation of transthyretin is detected in plasma and serum of humans with different types of hyperhomocysteinemia.
Vegetarianism produces subclinical malnutrition, hyperhomocysteinemia and atherogenesis.
Hyperinsulinism
Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults.
Hyperinsulinemia Provokes Synchronous Increases in Central Inflammation and {beta}-Amyloid in Normal Adults.
Hyperlipoproteinemia Type II
Development and Clinical Applications of Antisense Oligonucleotide Gapmers.
Invention and Early History of Gapmers.
Hypertension
A novel mouse model of advanced diabetic kidney disease.
Creatinine index and transthyretin as additive predictors of mortality in haemodialysis patients.
Hyperthyroidism
Transthyretin expression in the rat brain: effect of thyroid functional state and role in thyroxine transport.
Hyperthyroxinemia
A new family with hyperthyroxinemia caused by transthyretin Val109 misdiagnosed as thyrotoxicosis and resistance to thyroid hormone--a clinical research center study.
A novel variant of transthyretin (prealbumin), Thr119 to Met, associated with increased thyroxine binding.
A point mutation in transthyretin increases affinity for thyroxine and produces euthyroid hyperthyroxinemia.
Production and functional analysis of normal and variant recombinant human transthyretin proteins.
Thyroxine binding in a TTR Met 119 kindred.
Thyroxine binding to transthyretin Met 119. Comparative studies of different heterozygotic carriers and structural analysis.
Transthyretin mutations in hyperthyroxinemia and amyloid diseases.
X-ray crystal structure of the Ala-109-->Thr variant of human transthyretin which produces euthyroid hyperthyroxinemia.
[Thyroxine-binding proteins--familial euthyroid hyperthyroxinemia due to point mutations of transthyretin]
Hypertrophy, Left Ventricular
Plasma hepatocyte growth factor is a novel marker of AL cardiac amyloidosis.
Prevalence of transthyretin amyloid cardiomyopathy in male patients who underwent bilateral carpal tunnel surgery: The ACTUAL study.
Prevalence of transthyretin amyloidosis in patients with heart failure and no left ventricular hypertrophy.
Reduced trans-mitral A-wave velocity predicts the presence of wild-type transthyretin amyloidosis in elderly patients with left ventricular hypertrophy.
The electrocardiographic features associated with cardiac amyloidosis of variant transthyretin isoleucine 122 type in Afro-Caribbean patients.
Transthyretin Cardiac Amyloidosis.
Hypesthesia
Upper limb neuropathy such as carpal tunnel syndrome as an initial manifestation of ATTR Val30Met familial amyloid polyneuropathy.
Hypoalbuminemia
Down regulation of a harmful variant protein by replacement of its normal protein.
Hypotension, Orthostatic
A transthyretin variant (alanine 71) associated with familial amyloidotic polyneuropathy in a French family.
Blood pressure and orthostatic hypotension as measures of autonomic dysfunction in patients from the transthyretin amyloidosis outcomes survey (THAOS).
Familial Transthyretin Amyloidosis with Variant Asp38Ala Presenting with Orthostatic Hypotension and Chronic Diarrhea.
Orthostatic hypotension in hereditary transthyretin amyloidosis: epidemiology, diagnosis and management.
Hypothyroidism
CSF transthyretin in patients with depression.
Hypothyroidism Induced by Polychlorinated Biphenyls and Up-Regulation of Transthyretin.
Transthyretin is not necessary for thyroid hormone metabolism in conditions of increased hormone demand.
[Potentializing of tricyclics and serotoninergics by thyroid hormones in resistant depressive disorders]
Immune System Diseases
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.
Immunoglobulin Light-chain Amyloidosis
A practical approach to the diagnosis of systemic amyloidoses.
A review of the amyloidoses that infiltrate the heart.
A sporadic case of late-onset familial amyloid polyneuropathy with a monoclonal gammopathy.
Amyloid and peripheral nervous system disease.
Amyloid cardiomyopathy.
Amyloidosis and cardiovascular diseases: A clinical insight.
Amyloidosis.
Cardiac amyloidosis in African Americans: comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis.
Cardiac amyloidosis is associated with increased aortic stiffness.
Cardiac Amyloidosis: Diagnosis and Treatment Strategies.
Cardiac amyloidosis: the need for early diagnosis.
Cardiac Care of Patients with Cardiac Amyloidosis.
Clinical diagnosis and typing of systemic amyloidosis in subcutaneous fat aspirates by mass spectrometry-based proteomics.
Current treatment in cardiac amyloidosis.
Current trends in diagnosis and management of cardiac amyloidosis.
Diagnostic sensitivity of abdominal fat aspiration in cardiac amyloidosis.
Differential Myocyte Responses in Patients with Cardiac Transthyretin Amyloidosis and Light-Chain Amyloidosis: A Cardiac MR Imaging Study.
Imaging Techniques As An Aid In The Early Detection Of Cardiac Amyloidosis.
Keys to early diagnosis of cardiac amyloidosis: red flags from clinical, laboratory and imaging findings.
Macroglossia - not always AL amyloidosis.
Mass Spectrometric-Based Proteomic Analysis of Amyloid Neuropathy Type in Nerve Tissue.
Mucocutaneous manifestations in systemic amyloidosis A retrospective analytical study in a tertiary care center.
Multiparametric Echocardiography Scores for the Diagnosis of Cardiac Amyloidosis.
Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery.
Neurofilament light chain, a biomarker for polyneuropathy in systemic amyloidosis.
Non-invasive evaluation of the myocardial substrate of cardiac amyloidosis by gadolinium cardiac magnetic resonance.
Pupil abnormality in amyloidosis with autonomic neuropathy.
Renal Infarction and Its Consequences for Renal Function in Patients With Cardiac Amyloidosis.
Scientific Advances in and Clinical Approaches to Small-Fiber Polyneuropathy: A Review.
Sporadic transthyretin amyloidosis with a novel TTR gene mutation misdiagnosed as primary amyloidosis.
Two types of amyloidosis presenting in a single patient: a case series.
Use of biomarkers to diagnose and manage cardiac amyloidosis.
Wild-type transthyretin cardiac amyloidosis (ATTRwt-CA), previously known as senile cardiac amyloidosis: clinical presentation, diagnosis, management and emerging therapies.
[Amyloidosis and aging]
[An immunocytochemical study of alpha 1-antichymotrypsin in the senescent cerebral amyloid]
[Cardiac scintigraphy-centered diagnostic process in transthyretin cardiac amyloidosis].
[Senile systemic amyloidosis: definition, diagnosis, why thinking about?].
Infections
Biomarker discovery in subclinical mycobacterial infections of cattle.
C-reactive protein to transthyretin ratio for the early diagnosis and follow-up of postoperative infection.
Cloning and expression of the gene for soybean hydroxyisourate hydrolase. Localization and implications for function and mechanism.
Diagnostic value of C-reactive protein and transthyretin in bone infections of the lower limb.
Distinct neural stem cell tropism, early immune activation, and choroid plexus pathology following coxsackievirus infection in the neonatal central nervous system.
Effect of corticotherapy on proteomics of endometrial fluid from mares susceptible to persistent postbreeding endometritis.
Effect of Newcastle disease virus infection on vitamin A metabolism in chickens.
Effects of acute inflammation on plasma retinol, retinol-binding protein, and its mRNA in the liver and kidneys of vitamin A-sufficient rats.
Haemonchus contortus transthyretin domain - containing protein (HcTTR): A promising vaccine candidate against Haemonchus contortus infection.
Protein expression profiles distinguish between experimental invasive pulmonary aspergillosis and Pseudomonas pneumonia.
Repletion of the plasma pool of nutrient transport proteins occurs at different rates during the nutritional rehabilitation of severely malnourished children.
Sardinian Type 1 diabetes patients, Transthyretin and Mycobacterium avium subspecies paratuberculosis infection.
Serum transthyretin is a predictor of clinical outcomes in critically ill trauma patients.
The association between plasma levels of acute phase proteins, haptoglobin, alpha-1 acid glycoprotein (AGP), Pig-MAP, transthyretin and serum amyloid A (SAA) in Large White and Meishan pigs.
The molar ratio of serum retinol-binding protein (RBP) to transthyretin (TTR) is not useful to assess vitamin A status during infection in hospitalised children.
The negative acute phase response of serum transthyretin following Streptococcus suis infection in the pig.
Transthyretin amyloidosis and herpes zoster infection: a mimic of temporal arteritis.
Transthyretin as a potential biomarker for the differential diagnosis between lung cancer and lung infection.
[C-reactive protein and transthyretin in early diagnosis of infection after open fractures of the lower limbs (a preliminary study)]
Inflammatory Bowel Diseases
Retinol Binding Protein 4 in children with Inflammatory Bowel Disease: a negative correlation with the disease activity.
Influenza, Human
Rapidly progressive amyloid polyneuropathy associated with a novel variant transthyretin serine 25.
Insulin Resistance
ALTERED CIRCULATING LEVELS OF RETINOL BINDING PROTEIN 4 AND TRANSTHYRETIN IN RELATION TO INSULIN RESISTANCE, OBESITY, AND GLUCOSE INTOLERANCE IN ASIAN INDIANS.
Association between transthyretin concentrations and gestational diabetes mellitus in Chinese women.
Association of retinol binding protein 4 and transthyretin with triglyceride levels and insulin resistance in rural thais with high type 2 diabetes risk.
Elevated serum adiponectin and tumor necrosis factor-? and decreased transthyretin in Japanese elderly women with low grip strength and preserved muscle mass and insulin sensitivity.
Identification of cysteinylated transthyretin, a predictive biomarker of treatment response to partially hydrolyzed guar gum in type 2 diabetes rats, by surface-enhanced laser desorption/ionization time-of-flight mass spectrometry.
Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice.
Transthyretin contributes to insulin resistance and diminishes exercise-induced insulin sensitivity in obese mice by inhibiting AMPK activity in skeletal muscle.
Intellectual Disability
An association study between the transthyretin (TTR) gene and mental retardation.
Interatrial Block
The Prevalence of Advanced Interatrial Block and Its Relationship to Left Atrial Function in Patients with Transthyretin Cardiac Amyloidosis.
Iron Deficiencies
Recent advances in the treatment of chronic heart failure.
Serum transferrin receptor concentrations in women with mild malnutrition.
Iron Overload
Spectrum of Restrictive and Infiltrative Cardiomyopathies: Part 1 of a 2-Part Series.
Ischemic Stroke
Atrial Fibrillation and Ischemic Stroke With the Amyloidogenic V122I Transthyretin Variant Among Black Americans.
Cerebrospinal fluid transthyretin neuroprotection in a mouse model of brain ischemia.
Predictive value of serum transthyretin for outcome in acute ischemic stroke.
Kidney Diseases
Liver transplantation in transthyretin amyloidosis: Characteristics and management related to kidney disease.
Kidney Failure, Chronic
Characterization of end-stage renal disease after liver transplantation in transthyretin amyloidosis (ATTR V30M).
End-stage renal disease and dialysis in hereditary amyloidosis TTR V30M: presentation, survival and prognostic factors.
End-stage renal failure due to transthyretin amyloidosis after liver transplantation: outcomes in 19 registry cases.
Metabolism and clinical interest of serum transthyretin (prealbumin) in dialysis patients.
Observations with regard to the National Kidney Foundation K/DOQI clinical practice guidelines concerning serum transthyretin in chronic renal failure.
Proteomic analysis of plasma proteins of high-flux haemodialysis and on-line haemodiafiltration patients reveals differences in transthyretin levels related with anaemia.
Serum Retinol, Retinol-Binding Protein, and Transthyretin in Children Receiving Dialysis.
Leptospirosis
Potential serum biomarkers associated with mild and severe leptospirosis infection: A cohort study in the Malaysian population.
Leukemia
Substitution of murine transthyretin (prealbumin) regulatory sequences into the Moloney murine leukemia virus long terminal repeat yields infectious virus with altered biological properties.
[Transthyretin and albumin in cerebrospinal fluid in patients with acute leukemias or lymphomas of high grade malignancy]
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
CD5 molecule-like and transthyretin as putative biomarkers of chronic myeloid leukemia - an insight from the proteomic analysis of human plasma.
Small-Molecule Screening for Genetic Diseases.
Leukoencephalopathies
White matter disorders with autosomal dominant heredity: a review with personal clinical case studies and their MRI findings.
Liver Cirrhosis
Oral supplementation with branched-chain amino acids improves transthyretin turnover in rats with carbon tetrachloride-induced liver cirrhosis.
Liver Cirrhosis, Biliary
Impaired release of vitamin A from liver in primary biliary cirrhosis.
Liver Diseases
Amyloid Polyneuropathy and Myocardial Amyloidosis 10 Years after Domino Liver Transplantation from a Patient with a Transthyretin Ser50Arg Mutation.
Effect of tacrolimus and partial hepatectomy on transthyretin metabolism in rats.
Expression and function of thyroid hormone receptor variants in normal and chronically diseased human liver.
Relationship of insulin resistance to protein-energy malnutrition in patients with alcoholic liver cirrhosis: effect of short-term nutritional support.
Self-reported gastrointestinal symptoms are more common in liver transplanted transthyretin amyloidosis patients than in healthy controls and in patients transplanted for end-stage liver disease.
Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine.
Liver Failure
Iatrogenic amyloid polyneuropathy after domino liver transplantation.
Plasma levels of transthyretin and retinol-binding protein in Child-A cirrhotic patients in relation to protein-calorie status and plasma amino acids, zinc, vitamin A and plasma thyroid hormones.
Liver Neoplasms
Transthyretin (prealbumin) gene in human primary hepatic cancer.
Lung Neoplasms
A combined biomarker pattern improves the discrimination of lung cancer.
Diagnostic Value of Combining Tumor and Inflammatory Markers in Lung Cancer.
Effect and Mechanism of Transthyretin over-Expression on Proliferation and Cell Cycle of Lung Cancer A549 Cells.
Prognostic impact of serum transthyretin in patients with non-small cell lung cancer.
Proteomic analysis of serum in lung cancer induced by 3-methylcholanthrene.
Reduced transthyretin expression in sera of lung cancer.
Selective expression of transthyretin in subtypes of lung cancer.
Transthyretin as a potential biomarker for the differential diagnosis between lung cancer and lung infection.
Transthyretin Stimulates Tumor Growth through Regulation of Tumor, Immune, and Endothelial Cells.
[A new serum biomarker for lung cancer - transthyretin.]
Lymphocytic Choriomeningitis
Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells.
Lymphoma
[Transthyretin and albumin in cerebrospinal fluid in patients with acute leukemias or lymphomas of high grade malignancy]
Lymphoma, B-Cell
[Clinical Value of Serum Amyloid A and Misfolded Transthyretin for Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients].
Lymphoma, Large B-Cell, Diffuse
[Clinical Value of Serum Amyloid A and Misfolded Transthyretin for Relapsed/Refractory Diffuse Large B-Cell Lymphoma Patients].
Lymphoma, Non-Hodgkin
Amyloid and peripheral nervous system disease.
Lymphoma, T-Cell, Cutaneous
Confirmation of the biological significance of transthyretin as a biomarker for cutaneous T-cell lymphoma by its protein interaction partners.
Machado-Joseph Disease
Twenty Years of a Pre-Symptomatic Testing Protocol for Late-Onset Neurological Diseases in Portugal.
Macroglossia
High prevalence of recurrent nocturnal desaturations in systemic AL amyloidosis: a cross-sectional pilot study.
Pompe Disease Could Mimic Exam Findings of Amyloidosis: Two Rare Diagnoses Bona Fide.
Macular Degeneration
Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction: Potential Novel Therapeutics for Macular Degeneration, Transthyretin Amyloidosis, and Their Common Age-Related Comorbidities.
Malaria
The acute phase response and vitamin A status in malaria.
Malnutrition
Alteration of transthyretin microheterogeneity in serum of multiple trauma patients.
Assessment of nutritional status in organ transplant: is transthyretin a reliable indicator?
Assessment of the nutritional status of adult patients with acute myeloid leukemia during induction chemotherapy.
Assessment of Transthyretin Combined With Mini Nutritional Assessment on Admission Provides Useful Prognostic Information in Patients With Acute Decompensated Heart Failure.
Assessment of transthyretin cut-off values for a better screening of malnutrition: Retrospective determination and prospective validation.
Associations of decreased serum transthyretin with elevated high-sensitivity CRP, serum copper and decreased hemoglobin in ambulatory elderly women.
Biochemical indices to evaluate nutritional support for malignant disease.
Bioelectrical impedance analysis (BIA)-derived phase angle (PA) is a practical aid to nutritional assessment in hospital in-patients.
Body composition and nutritional parameters in HIV and AIDS patients.
Chemical pathology of homocysteine. V. Thioretinamide, thioretinaco, and cystathionine synthase function in degenerative diseases.
Clinical indications for plasma protein assays: transthyretin (prealbumin) in inflammation and malnutrition.
Exploring the Physiological Role of Transthyretin in Glucose Metabolism in the Liver.
Inflammation and disability as risk factors for mortality in elderly acute care patients.
Intestinal dysbiosis is common in systemic sclerosis and associated with gastrointestinal and extraintestinal features of disease.
Levels of plasma insulin-like growth factor I (IGF I), IGF II, IGF binding proteins, type 1 IGF receptor and growth hormone binding protein in community-dwelling elderly subjects with no malnutrition and no inflammation.
Low levels of plasma proteins: malnutrition or inflammation?
Malnutrition in alcoholic and virus-related cirrhosis.
Markers of nutritional status and inflammation in transthyretin cardiac amyloidosis: association with outcomes and the clinical phenotype.
Metabolism and clinical interest of serum transthyretin (prealbumin) in dialysis patients.
Nutritional depletion in patients on long-term oxygen therapy and/or home mechanical ventilation.
Nutritional regulation of visceral markers in rat liver and cultured hepatoma cells.
Nutritional status and muscle strength in patients with emphysema and severe alpha(1)-antitrypsin deficiency.
Quick and effective improvement of leucine enriched dietary supplement on malnutrition in acute stroke patients receiving enteral tube feeding.
Repletion of the plasma pool of nutrient transport proteins occurs at different rates during the nutritional rehabilitation of severely malnourished children.
Serum transferrin receptor concentrations in women with mild malnutrition.
Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition.
Short Nutritional Assessment Questionnaire as a predictor of undernutrition in cancer patients receiving outpatient chemotherapy: A retrospective study.
The role of visceral protein markers in protein calorie malnutrition.
Transthyretin (Prealbumin) and the Ambiguous Nature of Malnutrition.
Transthyretin for the routine assessment of malnutrition: A clinical dilemma highlighted by an international survey of experts in the field.
Transthyretin: its response to malnutrition and stress injury. clinical usefulness and economic implications.
[Assessment of nutritional status and body composition in patients with COPD: comparison of several methods]
[Transthyretin levels in serum and cerebrospinal fluid sustain the nutrio-viral hypothesis of the Cuban epidemic neuropathy]
Marfan Syndrome
Exome analysis of connective tissue dysplasia: Death and rebirth of clinical genetics?
Measles
A low molar ratio of retinol binding protein to transthyretin indicates vitamin A deficiency during inflammation: studies in rats and a posterior analysis of vitamin A-supplemented children with measles.
Vitamin a supplementation of vitamin a deficient measles patients lowers the risk of measles-related pneumonia in zambian children.
Medulloblastoma
Transthyretin expression in medulloblastomas and medulloblastoma cell lines.
Melanoma
Serum proteomic profile of cutaneous malignant melanoma and relation to cancer progression: Association to tumor derived alpha-N-acetylgalactosaminidase activity.
Memory Disorders
Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-?1-42 oligomers are revealed in vivo by using a novel animal model.
The common environmental pollutant dioxin-induced memory deficits by altering estrogen pathways and a major route of retinol transport involving transthyretin.
Transthyretin knockout mice display decreased susceptibility to AMPA-induced neurodegeneration.
Transthyretin: a key gene involved in the maintenance of memory capacities during aging.
Meningioma
Transthyretin expression in medulloblastomas and medulloblastoma cell lines.
Meningitis, Bacterial
Cerebrospinal fluid transthyretin in the neonate and blood-cerebrospinal fluid barrier permeability.
Meningitis, Viral
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Metabolic Diseases
Small fiber neuropathy: Diagnosis, causes, and treatment.
Small interfering RNA from the lab discovery to patients' recovery.
Metabolic Syndrome
Analysis of the factors contributing to serum retinol binding protein and transthyretin levels in Japanese adults.
Association of retinol binding protein 4 and transthyretin with triglyceride levels and insulin resistance in rural thais with high type 2 diabetes risk.
Transthyretin contributes to insulin resistance and diminishes exercise-induced insulin sensitivity in obese mice by inhibiting AMPK activity in skeletal muscle.
Migraine Disorders
Exome analysis of connective tissue dysplasia: Death and rebirth of clinical genetics?
Migraine with Aura
Exome analysis of connective tissue dysplasia: Death and rebirth of clinical genetics?
Miller Fisher Syndrome
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Mitral Valve Insufficiency
Cardiac devices in patients with transthyretin amyloidosis: Impact on functional class, left ventricular function, mitral regurgitation, and mortality.
Clinical practice update on heart failure 2019: pharmacotherapy, procedures, devices and patient management. An expert consensus meeting report of the Heart Failure Association of the European Society of Cardiology.
Recent advances in the treatment of chronic heart failure.
Monoclonal Gammopathy of Undetermined Significance
Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR).
Paraproteinemias and Peripheral Nerve Disease.
[Amyloid from insulin treatment: a pitfall for the pathologist and the diabetologist].
Mononeuropathies
Transthyretin amyloidosis presenting with multifocal demyelinating mononeuropathies.
Moyamoya Disease
Detection of a gamma-carboxy-glutamate as novel post-translational modification of human transthyretin.
Multiple Myeloma
Amyloid and peripheral nervous system disease.
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity.
Functional Amyloid Signaling via the Inflammasome, Necrosome, and Signalosome: New Therapeutic Targets in Heart Failure.
Gastrointestinal Tract Amyloidosis Presenting With Pneumatosis Intestinalis.
Paraproteinemias and Peripheral Nerve Disease.
Multiple Sclerosis
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Cerebrospinal fluid transthyretin in multiple sclerosis.
Oxidative modifications of cerebral transthyretin are associated with multiple sclerosis.
Muscle Weakness
A case of familial amyloid polyneuropathy (FAP ATTR Ile107Val) with proximal muscle weakness in the lower extremities.
A deceptive case of amyloid myopathy: clinical and magnetic resonance imaging features.
Muscular amyloid angiopathy with amyloidgenic transthyretin Ser50Ile and Tyr114Cys.
Muscular Atrophy
Muscular amyloid angiopathy with amyloidgenic transthyretin Ser50Ile and Tyr114Cys.
The Italian neuromuscular registry: a coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage.
Muscular Atrophy, Spinal
Comparison of the United Kingdom and United States approaches to approval of new neuromuscular therapies.
The Italian neuromuscular registry: a coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage.
[A selection of advances in neuromuscular medicine].
[Antisense therapies for neurological diseases].
Muscular Diseases
A case of transthyretin amyloidosis with myopathy, neuropathy, and cardiomyopathy resulting from an exceedingly rare mutation transthyretin Ala120Ser (c.418G?>?T, p.Ala140Ser).
A deceptive case of amyloid myopathy: clinical and magnetic resonance imaging features.
Muscular amyloid angiopathy with amyloidgenic transthyretin Ser50Ile and Tyr114Cys.
Transthyretin amyloidosis: Putting myopathy on the map.
Transthyretin V122I amyloidosis with clinical and histological evidence of amyloid neuropathy and myopathy.
Wild-type Transthyretin Amyloid Myopathy With an Inclusion Body Myositis Phenotype.
Muscular Dystrophy, Duchenne
The Italian neuromuscular registry: a coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage.
[Antisense therapies for neurological diseases].
Mycosis Fungoides
Confirmation of the biological significance of transthyretin as a biomarker for cutaneous T-cell lymphoma by its protein interaction partners.
Posttranslational modifications of transthyretin are serum markers in patients with mycosis fungoides.
Myocardial Infarction
Reversible myocardial oedema due to acute myocardial infarction as differential diagnosis of cardiac transthyretin amyloidosis.
Myocarditis
Inflammatory and Molecular Pathways in Heart Failure-Ischemia, HFpEF and Transthyretin Cardiac Amyloidosis.
Transradial left ventricular endomyocardial biopsy feasibility, safety and clinical usefulness: Initial experience of a tertiary university center.
Myopia
Correlation of misfolded transthyretin in abnormal vitreous and high myopia related ocular pathologies.
Functional analysis of misfolded transthyretin extracted from abnormal vitreous with high myopia related ocular pathologies.
Negative effects of transthyretin in high myopic vitreous on diabetic retinopathy.
Vitreous and serum levels of transthyretin (TTR) in high myopia patients are correlated with ocular pathologies.
Myositis
Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele.
Transthyretin Val122Ile, accumulated Abeta, and inclusion-body myositis aspects in cultured muscle.
Wild-type Transthyretin Amyloid Myopathy With an Inclusion Body Myositis Phenotype.
Myositis, Inclusion Body
Inclusion body myositis, muscle blood vessel and cardiac amyloidosis, and transthyretin Val122Ile allele.
Wild-type Transthyretin Amyloid Myopathy With an Inclusion Body Myositis Phenotype.
Neoplasm Metastasis
CM156, a sigma receptor ligand, reverses cocaine-induced place conditioning and transcriptional responses in the brain.
Comparative analysis of the prognostic utility of preoperative nutritional parameters in patients with resectable esophageal carcinoma.
Differential proteomic serum pattern of low molecular weight proteins expressed by adenocarcinoma lung cancer patients.
Neoplasms
2D-PAGE of ovarian cancer: analysis of soluble and insoluble fractions using medium-range immobilized pH gradients.
A 2-DE MALDI-TOF study to identify disease regulated serum proteins in lung cancer of c-myc transgenic mice.
A case of choroid plexus papilloma with stromal sclerosis and indistinct papillary structures.
A pediatric intramedullary spinal cord tumor with unusual solid-cystic and papillary features: a case report.
Amyloid and peripheral nervous system disease.
Amyloid in adrenal gland pheochromocytomas.
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity.
An ovarian cancer malignancy risk index composed of HE4, CA125, ultrasonographic score, and menopausal status: use in differentiation of ovarian cancers and benign lesions.
Biomarkers for the early detection of relapses in metastatic colorectal cancers.
Biomarkers of phenethyl isothiocyanate-mediated mammary cancer chemoprevention in a clinically relevant mouse model.
Cellular gene expression in papillomas of the choroid plexus from transgenic mice that express the simian virus 40 large T antigen.
Changes of transthyretin and clusterin after androgen ablation therapy and correlation with prostate cancer malignancy.
Choroid plexus papilloma in an infant.
Choroid plexus papilloma with stromal deposition of amyloid and elastic material.
Choroid plexus tumors in childhood. Histopathologic study and clinico-pathological correlation.
Clinicopathologic correlations in epithelial choroid plexus neoplasms: a study of 52 cases.
Clinicopathological features from long-term observation of a papillary tumor of the pineal region (PTPR): a case report.
Comparative analysis of the prognostic utility of preoperative nutritional parameters in patients with resectable esophageal carcinoma.
Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer.
Cytokeratin 7 and 20 expression in choroid plexus tumors: utility in differentiating these neoplasms from metastatic carcinomas.
Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice.
Detection of colorectal adenoma and cancer based on transthyretin and C3a-desArg serum levels.
Differential expression of transthyretin in papillary tumors of the endolymphatic sac and choroid plexus.
Differential proteome profiling of pleural effusions from lung cancer and benign inflammatory disease patients.
Differential proteomic serum pattern of low molecular weight proteins expressed by adenocarcinoma lung cancer patients.
Elevated risks for amyotrophic lateral sclerosis and blood disorders in Ashkenazi schizophrenic pedigrees suggest new candidate genes in schizophrenia.
Elevated serum adiponectin and tumor necrosis factor-? and decreased transthyretin in Japanese elderly women with low grip strength and preserved muscle mass and insulin sensitivity.
Estimating cancer risk from 99mTc pyrophosphate imaging for transthyretin cardiac amyloidosis.
Expression of renal cell markers and detection of 3p loss links endolymphatic sac tumor to renal cell carcinoma and warrants careful evaluation to avoid diagnostic pitfalls.
Four-year clinical and neuroradiological follow-up of a papillary tumor of the pineal region.
Hepatic gene expression changes in pigs experimentally infected with the lung pathogen Actinobacillus pleuropneumoniae as analysed with an innate immunity focused microarray.
Hydrophilic Small Molecules That Harness Transthyretin To Enhance the Safety and Efficacy of Targeted Chemotherapeutic Agents.
Hyperinsulinemia provokes synchronous increases in central inflammation and beta-amyloid in normal adults.
Hyperinsulinemia Provokes Synchronous Increases in Central Inflammation and {beta}-Amyloid in Normal Adults.
Immunohistochemical study of ependymal neoplasms: histological subtypes and glial and epithelial characteristics.
Investigation of serum proteome alterations in human glioblastoma multiforme.
Low Transthyretin Levels Predict Poor Prognosis in Cancer Patients in Palliative Care Settings.
Papillary neuroepithelial tumor of the pineal region. A case report.
Plasma proteomics analysis of tamoxifen resistance in breast cancer.
Plasma retinol transport system and taste acuity in patients with obstructive jaundice.
Pre-treatment plasma proteomic markers associated with survival in oesophageal cancer.
Pressure-temperature folding landscape in proteins involved in neurodegenerative diseases and cancer.
Prognosis and histopathologic features in papillary tumors of the pineal region: a retrospective multicenter study of 31 cases.
Prognostic Value of Pretreatment Serum Transthyretin Level in Patients with Gastrointestinal Cancers.
Proteomics based drug repositioning applied to improve in vitro fertilization implantation: an artificial intelligence model.
Rapid T cell-based identification of human tumor tissue antigens by automated two-dimensional protein fractionation.
Serum glutamine and hospital-acquired infections after aneurysmal subarachnoid hemorrhage.
Serum proteomics of lung adenocarcinomas induced by targeted overexpression of c-raf in alveolar epithelium identifies candidate biomarkers.
Serum transthyretin level is associated with prognosis of patients with gastric cancer.
Tc-99m pyrophosphate imaging for transthyretin cardiac amyloidosis: Importance of estimation of cancer risk with the modality.
The expression of viral and cellular genes in papillomas of the choroid plexus induced in transgenic mice.
Transthyretin and cystatin C are catabolized in proximal tubular epithelial cells and the proteins are not useful as markers for renal cell carcinomas.
Transthyretin expression in medulloblastomas and medulloblastoma cell lines.
Transthyretin immunoreactivity in choroid plexus neoplasms and brain metastases.
Transthyretin in endocrine pancreatic tumors.
Transthyretin messenger ribonucleic acid expression in the pancreas and in endocrine tumors of the pancreas and gut.
Transthyretin Stimulates Tumor Growth through Regulation of Tumor, Immune, and Endothelial Cells.
Transthyretin--an explanation of "anomalous" serum thyroid hormone values in severe illness?
Transthyretin-driven oncolytic adenovirus suppresses tumor growth in orthotopic and ascites models of hepatocellular carcinoma.
Validation of serum biomarkers for detection of early-stage ovarian cancer.
[Immunohistochemical study on distribution of transthyretin in normal human brain tissue and tumors]
[Mechanisms of electroacupuncture for improving Alzheimer's disease from reducing ? amyloid protein level].
[Prognostic markers in the histopathological diagnosis of tumors of the choroid plexus]
[Transthyretin and albumin in cerebrospinal fluid in patients with acute leukemias or lymphomas of high grade malignancy]
[Vitamins A and E in digestive cancers]
Neoplastic Cells, Circulating
Biomarkers for the early detection of relapses in metastatic colorectal cancers.
Nephrotic Syndrome
The Accumulation of Heparan Sulfate S-Domains in Kidney Transthyretin Deposits Accelerates Fibril Formation and Promotes Cytotoxicity.
Nervous System Diseases
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Capture of a dimeric intermediate during transthyretin amyloid formation.
TTR-FAP Progression Evaluation Based on Gait Analysis Using a Single RGB-D Camera.
Neuralgia
Biomarkers mapping of neuropathic pain in a nerve chronic constriction injury mice model.
Characterization of Pain in Familial Amyloid Polyneuropathy.
Multimodality Imaging of Cardiac Transthyretin Amyloidosis 16 years after a Domino Liver Transplantation.
Small fiber neuropathy: Diagnosis, causes, and treatment.
Spinal cord stimulation markedly ameliorated refractory neuropathic pain in transthyretin Val30Met familial amyloid polyneuropathy.
Neurilemmoma
Pro-oxidative effects of aggregated transthyretin in human Schwannoma cells.
Neuroblastoma
Receptor-mediated uptake and internalization of transthyretin.
The heat shock response in FAP: the role of the extracellular chaperone clusterin.
The impact of V30A mutation on transthyretin protein structural stability and cytotoxicity against neuroblastoma cells.
The systemic amyloid precursor transthyretin (TTR) behaves as a neuronal stress protein regulated by HSF1 in SH-SY5Y human neuroblastoma cells and APP23 Alzheimer's disease model mice.
Transthyretin inhibition of amyloid beta aggregation and toxicity.
Neurodegenerative Diseases
Activation of ERK1/2 MAP kinases in Familial Amyloidotic Polyneuropathy.
Activation of the heat shock response in familial amyloidotic polyneuropathy.
alphaB-crystallin (HspB5) in familial amyloidotic polyneuropathy.
An overview of drugs currently under investigation for the treatment of transthyretin-related hereditary amyloidosis.
Animal models of human amyloidoses: are transgenic mice worth the time and trouble?
Carvedilol treatment reduces transthyretin deposition in a familial amyloidotic polyneuropathy mouse model.
Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy.
Curcumin could reduce the monomer of TTR with Tyr114Cys mutation via autophagy in cell model of familial amyloid polyneuropathy.
Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates.
Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models.
Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways.
Gene therapy approach to FAP: in vivo influence of T119M in TTR deposition in a transgenic V30M mouse model.
Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging.
Impairment of the ubiquitin-proteasome system associated with extracellular transthyretin aggregates in familial amyloidotic polyneuropathy.
In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE).
Misfolded transthyretin causes behavioral changes in a Drosophila model for transthyretin-associated amyloidosis.
MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy.
Neurodegeneration in familial amyloid polyneuropathy: from pathology to molecular signaling.
Oligomeric TTR V30M aggregates compromise cell viability, erythropoietin gene expression and promoter activity in the human hepatoma cell line Hep3B.
Structural stabilization of transthyretin by a new compound, 6-benzoyl-2-hydroxy-1H-benzo[de]isoquinoline-1,3(2H)-dione.
Synthesis and structural analysis of halogen substituted fibril formation inhibitors of Human Transthyretin (TTR).
Tafamidis for transthyretin amyloidosis.
The Expression of Chemokines Is Downregulated in a Pre-Clinical Model of TTR V30M Amyloidosis.
The putative role of some conserved water molecules in the structure and function of human transthyretin.
The sour side of neurodegenerative disorders: the effects of protein glycation.
Transthyretin enhances nerve regeneration.
Transthyretin interacts with actin regulators in a Drosophila model of familial amyloid polyneuropathy.
Transthyretin internalization by sensory neurons is megalin mediated and necessary for its neuritogenic activity.
Transthyretin is not expressed by dorsal root ganglia cells.
Uptake of aggregating transthyretin by fat body in a Drosophila model for TTR-associated amyloidosis.
Variants in RBP4 and AR genes modulate age at onset in familial amyloid polyneuropathy (FAP ATTRV30M).
Neuroinflammatory Diseases
Intranasal Losartan Decreases Perivascular Beta Amyloid, Inflammation, and the Decline of Neurogenesis in Hypertensive Rats.
Neuromuscular Diseases
Nutritional depletion in patients on long-term oxygen therapy and/or home mechanical ventilation.
Non-alcoholic Fatty Liver Disease
Serum proteomic analysis of diet-induced steatohepatitis and metabolic syndrome in the Ossabaw miniature swine.
Obesity
ALTERED CIRCULATING LEVELS OF RETINOL BINDING PROTEIN 4 AND TRANSTHYRETIN IN RELATION TO INSULIN RESISTANCE, OBESITY, AND GLUCOSE INTOLERANCE IN ASIAN INDIANS.
Association of retinol binding protein 4 and transthyretin with triglyceride levels and insulin resistance in rural thais with high type 2 diabetes risk.
Protein profiling of low-density lipoprotein from obese subjects.
The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker.
Osteoarthritis
A case report of osteoarthritis associated with hereditary transthyretin amyloidosis ATTRV30M.
Expression of proteins in serum, synovial fluid, synovial membrane, and articular cartilage samples obtained from dogs with stifle joint osteoarthritis secondary to cranial cruciate ligament disease and dogs without stifle joint arthritis.
The delaying effect of alpha-glycerophosphocholine on senescence, transthyretin deposition, and osteoarthritis in senescence-accelerated mouse prone 8 mice.
Transthyretin deposition in articular cartilage: a novel mechanism in the pathogenesis of osteoarthritis.
Transthyretin deposition promotes progression of osteoarthritis.
Osteoarthritis, Knee
Knee osteoarthritis associated with different kinds of amyloid deposits and the impact of aging on type of amyloid.
Osteoporosis
Decreased retinol transport proteins in Thai post-menopausal women with osteoporosis.
Ovarian Diseases
Development of multiplexed bead-based immunoassays for the detection of early stage ovarian cancer using a combination of serum biomarkers.
Ovarian Neoplasms
A novel proteomic biomarker panel as a diagnostic tool for patients with ovarian cancer.
An ovarian cancer malignancy risk index composed of HE4, CA125, ultrasonographic score, and menopausal status: use in differentiation of ovarian cancers and benign lesions.
Classification of cancer types by measuring variants of host response proteins using SELDI serum assays.
Development of multiplexed bead-based immunoassays for the detection of early stage ovarian cancer using a combination of serum biomarkers.
Evaluation of apolipoprotein A1 and posttranslationally modified forms of transthyretin as biomarkers for ovarian cancer detection in an independent study population.
Evaluation of HE4 and TTR for diagnosis of ovarian cancer: Comparison with CA-125.
Microheterogeneity of transthyretin in serum and ascitic fluid of ovarian cancer patients.
Multi-peptide nLC-PC-IDMS-SRM-based assay for the quantification of biomarkers in the chicken ovarian cancer model.
Proteomic biomarkers for overall and progression-free survival in ovarian cancer patients.
Proteomic biomarkers in combination with CA 125 for detection of epithelial ovarian cancer using prediagnostic serum samples from the prostate, lung, colorectal, and ovarian (PLCO) cancer screening trial.
Transthyretin, a biomarker for nutritional status and ovarian cancer.
Two-dimensional electrophoretic proteome study of serum thermostable fraction from patients with various tumor conditions.
Validation of serum biomarkers for detection of early-stage ovarian cancer.
Pancreatic Neoplasms
Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer.
Pancreatitis
Protein status in pancreatitis--transthyretin is a sensitive biomarker of malnutrition in acute and chronic pancreatitis.
Pancreatitis, Chronic
Confounding effect of obstructive jaundice in the interpretation of proteomic plasma profiling data for pancreatic cancer.
Papilledema
Macular and optic disc edema and retinal vascular leakage in familial amyloid polyneuropathy with a transthyretin Val30Met mutation: a case report.
Papilloma
Choroid plexus papilloma with stromal deposition of amyloid and elastic material.
Differential expression of transthyretin in papillary tumors of the endolymphatic sac and choroid plexus.
Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach.
Primary choroid plexus papilloma located in the suprasellar region: case report.
Tumors of the choroid plexus.
[Immunohistochemical study for choroid plexus papillomas and ependymomas]
Papilloma, Choroid Plexus
Choroid plexus papilloma with stromal deposition of amyloid and elastic material.
Differential expression of transthyretin in papillary tumors of the endolymphatic sac and choroid plexus.
Identification of novel diagnostic markers for choroid plexus tumors: a microarray-based approach.
Primary choroid plexus papilloma located in the suprasellar region: case report.
Tumors of the choroid plexus.
[Immunohistochemical study for choroid plexus papillomas and ependymomas]
Paralysis
Coexistence of transthyretin familial amyloid polyneuropathy and hereditary neuropathy with liability to pressure palsy.
Paraproteinemias
Amyloidosis and Unexpected Death: A Review of Seven Cases.
Amyloidosis as a Systemic Disease in Context.
Amyloidosis: Multisystem Spectrum of Disease with Pathologic Correlation.
Canadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis.
Cardiac amyloidosis: the need for early diagnosis.
Coexistent transthyretin amyloid cardiomyopathy and monoclonal gammopathy: Diagnostic challenges and prognostic implications.
Diagnosis of amyloid neuropathy.
Diagnosis of small fiber neuropathy: A comparative study of five neurophysiological tests.
Familial amyloidosis in a large Spanish kindred resulting from a D38V mutation in the transthyretin gene.
Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients.
Interstitial amyloidosis in sporadic inclusion body myositis.
Isolated atrial amyloidosis and the importance of molecular classification.
Medullary amyloidosis associated with apolipoprotein A-IV deposition.
Monoclonal Gammopathy of Uncertain Significance and Transthyretin Cardiac Amyloidosis.
Monoclonal gammopathy of undetermined significance in systemic transthyretin amyloidosis (ATTR).
Paraproteinemias and Peripheral Nerve Disease.
Prevalence of Monoclonal Gammopathy in Wild-Type Transthyretin Amyloidosis.
Senile transthyretin cardiac amyloidosis in patients with plasma cell dyscrasias: importance of cardiac biopsy for making the correct diagnosis.
Strong transthyretin immunostaining: potential pitfall in cardiac amyloid typing.
Transthyretin amyloidosis with pulmonary involvement in a patient with monoclonal gammapathy.
Value of Longitudinal Strain to Identify Wild-Type Transthyretin Amyloidosis in Patients With Aortic Stenosis.
[Amyloid from insulin treatment: a pitfall for the pathologist and the diabetologist].
Paratuberculosis
Biomarker discovery in subclinical mycobacterial infections of cattle.
Sardinian Type 1 diabetes patients, Transthyretin and Mycobacterium avium subspecies paratuberculosis infection.
Paresthesia
Familial amyloid polyneuropathy involving a homozygous Val30Met mutation in the amyloidogenic transthyretin gene presenting with superficial siderosis: a case report.
Small fiber neuropathy: Diagnosis, causes, and treatment.
Parkinson Disease
Alanine-to-threonine substitutions and amyloid diseases: Butyrylcholinesterase as a case study.
Chromolaena odorata (Siam weed): A natural reservoir of bioactive compounds with potent anti-fibrillogenic, antioxidative, and cytocompatible properties.
Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins.
Imaging Amyloid Tissues Stained with Luminescent Conjugated Oligothiophenes by Hyperspectral Confocal Microscopy and Fluorescence Lifetime Imaging.
Nucleobindin 1 binds to multiple types of pre-fibrillar amyloid and inhibits fibrillization.
Use of haptoglobin and transthyretin as potential biomarkers for the preclinical diagnosis of Parkinson's disease.
Peripheral Nervous System Diseases
6MWT performance correlates with peripheral neuropathy but not with cardiac involvement in patients with hereditary transthyretin amyloidosis (hATTR).
A new transthyretin mutation associated with amyloid cardiomyopathy.
A new transthyretin variant (Glu61Gly) associated with cardiomyopathy.
A new transthyretin variant--ATTR Arg104Cys.
A novel amyloidogenic transthyretin variant, Gly53Ala, associated with intermittent headaches and ataxia.
A novel ATTR L32V mutation causes familial amyloid polyneuropathy in a Bolivian family.
A Patient With Hereditary ATTR and a Novel AGel p.Ala578Pro Amyloidosis.
A transthyretin mutation (Tyr78Phe) associated with peripheral neuropathy, carpal tunnel syndrome and skin amyloidosis.
Binding of amyloidogenic transthyretin to the plasma membrane alters membrane fluidity and induces neurotoxicity.
Brazilian consensus for diagnosis, management and treatment of transthyretin familial amyloid polyneuropathy.
Burden of hereditary transthyretin amyloidosis on quality of life.
Cardiomyopathy in a Japanese family with the Glu61Lys transthyretin variant: a new phenotype.
Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy.
Demyelinating Neuropathy in a Patient Treated With Revusiran for Transthyretin (Thr60Ala) Amyloidosis.
Discordant phenotype in monozygotic female twins with Lys35Thr TTR familial amyloidotic polyneuropathy.
Electro-clinical presentation of hereditary transthyretin related amyloidosis when presenting as a polyneuropathy of unknown origin in northern France.
Electrophysiological parameters that contribute to the pathogenesis of familial amyloid polyneuropathy caused by transthyretin mutations.
Homozygosity for the transthyretin-Met30-gene in seven individuals with familial amyloidosis with polyneuropathy detected by restriction enzyme analysis of amplified genomic DNA sequences.
Identification of a novel TTR Gly67Glu mutant and the first case series of familial transthyretin amyloidosis in Hong Kong Chinese.
Isolated atrial amyloidosis suspected by electrophysiological voltage mapping and diagnosed by 99m Tc-DPD scintigraphy.
Late-onset peripheral neuropathy in patients with wild type transthyretin amyloidosis (wtATTR).
Meningocerebrovascular amyloidosis associated with a novel transthyretin mis-sense mutation at codon 18 (TTRD 18G)
Ostertag revisited: the inherited systemic amyloidoses without neuropathy.
Paraproteinemias and Peripheral Nerve Disease.
Peripheral neuropathy symptoms in wild type transthyretin amyloidosis.
Plasma neurofilament light chain concentration is increased and correlates with the severity of neuropathy in hereditary transthyretin amyloidosis.
Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis.
Rate of progression of transthyretin amyloidosis.
Technetium pyrophosphate myocardial uptake and peripheral neuropathy in a rare variant of familial transthyretin (TTR) amyloidosis (Ser23Asn): a case report and literature review.
Transthyretin amyloid neuropathy has earlier neural involvement but better prognosis than primary amyloid counterpart: an answer to the paradox?
Transthyretin amyloidosis (serine 44) with headache, hearing loss, and peripheral neuropathy.
Transthyretin amyloidosis: a new mutation associated with dementia.
Transthyretin amyloidosis: Putting myopathy on the map.
Transthyretin RNA profiling in livers from transplanted patients affected by familial amyloidotic polyneuropathy, and identification of a dual transcription start point.
[Amyloid neuropathy resulting from an unknown protein.]
[An immunocytochemical study of alpha 1-antichymotrypsin in the senescent cerebral amyloid]
Phenylketonurias
Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid.
Pneumonia
A case of wild-type transthyretin amyloidosis associated with organizing pneumonia.
Protein expression profiles distinguish between experimental invasive pulmonary aspergillosis and Pseudomonas pneumonia.
POEMS Syndrome
Paraproteinemias and Peripheral Nerve Disease.
Polymyositis
A deceptive case of amyloid myopathy: clinical and magnetic resonance imaging features.
Polyneuropathies
1H-NMR structural studies of a cystine-linked peptide containing residues 71-93 of transthyretin and effects of a Ser84 substitution implicated in familial amyloidotic polyneuropathy.
4'-iodo-4'-deoxydoxorubicin and tetracyclines disrupt transthyretin amyloid fibrils in vitro producing noncytotoxic species: screening for TTR fibril disrupters.
99mTc-DPD scintigraphy in transthyretin-related familial amyloidotic polyneuropathy.
A basic transthyretin variant (Glu61-->Lys) causes familial amyloidotic polyneuropathy: protein and DNA sequencing and PCR-induced mutation restriction analysis.
A case of biopsy-proven leptomeningeal amyloidosis and intravenous Ig-responsive polyneuropathy associated with the Ala25Thr transthyretin gene mutation.
A case of familial amyloid polyneuropathy homozygous for the transthyretin Val30Met gene with motor-dominant sensorimotor polyneuropathy and unusual sural nerve pathological findings.
A case of hereditary amyloidosis transthyretin variant Met 30 with amyloid cardiomyopathy, less polyneuropathy, and the presence of giant cells.
A case of vitreous amyloidosis without systemic symptoms in familial amyloidotic polyneuropathy.
A chemometric approach for characterization of serum transthyretin in familial amyloidotic polyneuropathy type I (FAP-I) by electrospray ionization-ion mobility mass spectrometry.
A different amyloid formation mechanism: de novo oculoleptomeningeal amyloid deposits after liver transplantation.
A double-variant transthyretin allele (Ser 6, Ile 33) in the Israeli patient "SKO" with familial amyloidotic polyneuropathy.
A low amyloidogenic E61K transthyretin mutation may cause familial amyloid polyneuropathy.
A Narrative Review of the Role of Transthyretin in Health and Disease.
A new diagnostic procedure to detect unknown transthyretin (TTR) mutations in familial amyloidotic polyneuropathy (FAP).
A New Folding Kinetic Mechanism for Human Transthyretin and the Influence of the Amyloidogenic V30M Mutation.
A new nonamyloid transthyretin variant, G101S, detected by electrospray ionization/mass spectrometry. Mutations in brief no. 201. Online.
A new transthyretin variant from a patient with familial amyloidotic polyneuropathy has asparagine substituted for histidine at position 90.
A non-invasive method based on saliva to characterize transthyretin in familial amyloidotic polyneuropathy patients using FT-ICR high-resolution MS.
A novel tool for detecting amyloid deposits in systemic amyloidosis in vitro and in vivo.
A novel transthyretin mutation associated with familial amyloidotic polyneuropathy.
A novel transthyretin mutation at position 30 (Leu for Val) associated with familial amyloidotic polyneuropathy.
A novel transthyretin mutation V32A in a Chinese man with late-onset amyloid polyneuropathy.
A Novel Variant Mutation of Transthyretin Ile73Val-Related Amyloidotic Polyneuropathy in Taiwanese.
A novel variant of transthyretin (Glu89Lys) associated with familial amyloidotic polyneuropathy.
A novel variant of transthyretin (Tyr114 to Cys) deduced from the nucleotide sequences of gene fragments from familial amyloidotic polyneuropathy in Japanese sibling cases.
A phase II, open-label, extension study of long-term patisiran treatment in patients with hereditary transthyretin-mediated (hATTR) amyloidosis.
A possible role for miRNA silencing in disease phenotype variation in Swedish transthyretin V30M carriers.
A Review of Patisiran (ONPATTRO®) for the Treatment of Polyneuropathy in People with Hereditary Transthyretin Amyloidosis.
A second transthyretin mutation at position 33 (Leu/Phe) associated with familial amyloidotic polyneuropathy.
A severe form of amyloidotic polyneuropathy in a Costa Rican family with a rare transthyretin mutation (Glu54Lys).
A transgenic rat with the human ATTR V30M: a novel tool for analyses of ATTR metabolisms.
A transthyretin variant (alanine 49) associated with familial amyloidotic polyneuropathy in a French family.
A transthyretin variant (alanine 71) associated with familial amyloidotic polyneuropathy in a French family.
A trinucleotide deletion in the transthyretin gene (delta V 122) in a kindred with familial amyloidotic polyneuropathy.
Abnormal transthyretin in asymptomatic relatives in familial amyloidotic polyneuropathy.
Accelerating restrictive cardiomyopathy after liver transplantation in a patient with familial amyloidotic polyneuropathy: a case report.
Activation of ERK1/2 MAP kinases in Familial Amyloidotic Polyneuropathy.
Activation of the heat shock response in familial amyloidotic polyneuropathy.
Advanced glycation end products (AGE) and the receptor for AGE are present in gastrointestinal tract of familial amyloidotic polyneuropathy patients but do not induce NF-kappaB activation.
Advances in Treatment of ATTRv Amyloidosis: State of the Art and Future Prospects.
Aging and transthyretin-related amyloidosis: pathologic examinations in pulmonary amyloidosis.
Ala97Ser transthyretin amyloidosis-associated polyneuropathy, clinical and neurophysiological profiles in a Thai cohort.
alphaB-crystallin (HspB5) in familial amyloidotic polyneuropathy.
Alteration in molecular structure which results in disease: the Met-30 variant of human plasma transthyretin.
Amyloid and nonfibrillar deposits in mice transgenic for wild-type human transthyretin: a possible model for senile systemic amyloidosis.
Amyloid and peripheral nervous system disease.
Amyloid deposition in a mouse model humanized at the transthyretin and retinol-binding protein 4 loci.
Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology.
Amyloid deposits inside myocardial fibers in transthyretin-Met30 familial amyloidotic polyneuropathy. A histological and biochemical study.
Amyloid fibril composition is related to the phenotype of hereditary transthyretin V30M amyloidosis.
Amyloid fibril protein in familial amyloidotic polyneuropathy, Portuguese type. Definition of molecular abnormality in transthyretin (prealbumin).
Amyloid Polyneuropathy Caused By Wild-Type Transthyretin.
Amyloid proteins and amyloidoses: complexity updated.
Amyloidogenic and anti-amyloidogenic properties of recombinant transthyretin variants.
Amyloidosis and Ocular Involvement: an Overview.
Amyloidosis of the Breast: Three Different and Unusual Presentations of a Rare Entity.
An aggressive familial amyloidotic polyneuropathy caused by a new variant transthyretin Lys 54.
An Italian family with Ala-47 transthyretin mutation associated with cardiomyopathy and polyneuropathy.
An unusual transthyretin gene missense mutation (TTR Phe33Val) linked to familial amyloidotic polyneuropathy.
Analysis of amyloid deposition in a transgenic mouse model of homozygous familial amyloidotic polyneuropathy.
Analysis of Mitochondrial Haplogroups Associated With TTR Val30Ala Familial Amyloidotic Polyneuropathy in Chinese Patients.
Analysis of transthyretin amyloid fibrils from vitreous samples in familial amyloidotic polyneuropathy (Val30Met).
Analysis of transthyretin in human serum by capillary zone electrophoresis electrospray ionization time-of-flight mass spectrometry. Application to familial amyloidotic polyneuropathy type I.
Analysis of x-ray diffraction patterns from amyloid of biopsied vitreous humor and kidney of transthyretin (TTR) Met30 familial amyloidotic polyneuropathy (FAP) patients: axially arrayed TTR monomers constitute the protofilament.
Anti-apoptotic treatment reduces transthyretin deposition in a transgenic mouse model of Familial Amyloidotic Polyneuropathy.
Antibody recognition of amyloidogenic transthyretin variants in serum of patients with familial amyloidotic polyneuropathy.
Applications of gene therapy for familial amyloidotic polyneuropathy.
Applying an artificial neural network model for developing a severity score for patients with hereditary amyloid polyneuropathy.
Association of C3 and C4A complement types with familial amyloidotic polyneuropathy.
Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis: The APOLLO Study.
Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry.
Beyond genetic factors in familial amyloidotic polyneuropathy: protein glycation and the loss of fibrinogen's chaperone activity.
Bilateral optic neuropathy in a patient with familial amyloidotic polyneuropathy.
Biochemical and genetic characterization of type I familial amyloidotic polyneuropathy.
Biochemical marker in familial amyloidotic polyneuropathy, Portuguese type. Family studies on the transthyretin (prealbumin)-methionine-30 variant.
Biomarkers in the assessment of therapies for familial amyloidotic polyneuropathy.
Biophysical analyses of the transthyretin variants, Tyr114His and Tyr116Ser, associated with familial amyloidotic polyneuropathy.
Brazilian consensus for diagnosis, management and treatment of transthyretin familial amyloid polyneuropathy.
Canadian Guidelines for Hereditary Transthyretin Amyloidosis Polyneuropathy Management.
Capture of a dimeric intermediate during transthyretin amyloid formation.
Cardiac amyloidosis: a review and report of a new transthyretin (prealbumin) variant.
Carvedilol treatment reduces transthyretin deposition in a familial amyloidotic polyneuropathy mouse model.
Cellular consequences of transthyretin deposition.
Cerebrospinal fluid and vitreous body exposure to orally administered tafamidis in hereditary ATTRV30M (p.TTRV50M) amyloidosis patients.
Chain reaction of amyloid fibril formation with induction of basement membrane in familial amyloidotic polyneuropathy.
Chance or challenge, spoilt for choice? New recommendations on diagnostic and therapeutic considerations in hereditary transthyretin amyloidosis with polyneuropathy: the German/Austrian position and review of the literature.
Change in variant transthyretin levels in patients with familial amyloidotic polyneuropathy type I following liver transplantation.
Characterisation of serum transthyretin by electrospray ionisation-ion mobility mass spectrometry: Application to familial amyloidotic polyneuropathy type I (FAP-I).
Characteristics of Patients with Hereditary Transthyretin Amyloidosis and an Evaluation of the Safety of Tafamidis Meglumine in Japan: An Interim Analysis of an All-case Postmarketing Surveillance.
Characterization of a transthyretin (prealbumin) variant associated with familial amyloidotic polyneuropathy type II (Indiana/Swiss).
Characterization of cysteine and homocysteine bound to human serum transthyretin.
Characterization of end-stage renal disease after liver transplantation in transthyretin amyloidosis (ATTR V30M).
Characterization of Pain in Familial Amyloid Polyneuropathy.
Cholesterol and anionic phospholipids increase the binding of amyloidogenic transthyretin to lipid membranes.
Chromium(III) ion and thyroxine cooperate to stabilize the transthyretin tetramer and suppress in vitro amyloid fibril formation.
Clinical 3-D Gait Assessment of Patients With Polyneuropathy Associated With Hereditary Transthyretin Amyloidosis.
Clinical and histopathological features of familial amyloidotic polyneuropathy with transthyretin Val30Ala in a Chinese family.
Clinical and pathological findings in familial amyloid polyneuropathy caused by a transthyretin E61K mutation.
Clinicopathological features of senile systemic amyloidosis: an ante- and post-mortem study.
Clusterin overexpression and its possible protective role in transthyretin deposition in familial amyloidotic polyneuropathy.
Clusterin regulates transthyretin amyloidosis.
CNS involvement in V30M transthyretin amyloidosis: clinical, neuropathological and biochemical findings.
Combined heart and liver transplantation for familial amyloidotic neuropathy.
Common origin of the Val30Met mutation responsible for the amyloidogenic transthyretin type of familial amyloidotic polyneuropathy.
Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin.
Comparative studies of two transthyretin variants with protective effects on familial amyloidotic polyneuropathy: TTR R104H and TTR T119M.
Comparison of quantitative sensory testing and heart rate variability in Swedish Val30Met ATTR.
Complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuropathy TTR Val30Met.
Continuous development of arrhythmia is observed in Swedish transplant patients with familial amyloidotic polyneuropathy (amyloidogenic transthyretin Val30Met variant).
Correction to: A Review of Patisiran (ONPATTRO®) for the Treatment of Polyneuropathy in People with Hereditary Transthyretin Amyloidosis.
Curcumin: A multi-target disease-modifying agent for late-stage transthyretin amyloidosis.
Cutaneous nerve biomarkers in transthyretin familial amyloid polyneuropathy.
Cys114-linked dimers of transthyretin are compatible with amyloid formation.
Cysteine 10 is a key residue in amyloidogenesis of human transthyretin Val30Met.
Decreased thermodynamic stability as a crucial factor for familial amyloidotic polyneuropathy.
Denervation of eccrine glands in patients with familial amyloidotic polyneuropathy type I.
Deposition of transthyretin amyloid is not accelerated by the same amyloid in vivo.
Deposition of transthyretin in early stages of familial amyloidotic polyneuropathy: evidence for toxicity of nonfibrillar aggregates.
Description of transthyretin S50A, S52P and G47A mutations in familial amyloidosis polyneuropathy.
Destabilization of transthyretin by pathogenic mutations in the DE loop.
Detection and characterization of aggregates, prefibrillar amyloidogenic oligomers, and protofibrils using fluorescence spectroscopy.
Detection of different forms of variant transthyretin (Met30) in cerebrospinal fluid.
Detection of three transthyretin gene mutations in familial amyloidotic polyneuropathy by analysis of DNA extracted from formalin-fixed and paraffin-embedded tissues.
Development and validation of a liquid chromatography-tandem mass spectrometry method for the assay of tafamidis in rat plasma: Application to a pharmacokinetic study in rats.
Diagnosis and Treatment of Hereditary Transthyretin Amyloidosis (hATTR) Polyneuropathy: Current Perspectives on Improving Patient Care.
Diagnosis of familial amyloidotic polyneuropathy in Sweden by RFLP analysis.
Diagnostic challenges in hereditary transthyretin amyloidosis with polyneuropathy: avoiding misdiagnosis of a treatable hereditary neuropathy.
Diagnostic radioimmunoassay and DNA-analysis in Swedish and Japanese patients with familial amyloidotic polyneuropathy. Homozygosity for the TTR met30 gene.
Diflunisal tolerability in transthyretin cardiac amyloidosis: a single center's experience.
Dimeric transthyretin variant assembles into spherical neurotoxins.
Discordant penetrance of the trait for familial amyloidotic polyneuropathy in two pairs of monozygotic twins.
Discordant phenotype in monozygotic female twins with Lys35Thr TTR familial amyloidotic polyneuropathy.
DISCOVERY: prevalence of transthyretin (TTR) mutations in a US-centric patient population suspected of having cardiac amyloidosis.
Disulfide-bond formation in the transthyretin mutant Y114C prevents amyloid fibril formation in vivo and in vitro.
DJ-1 degrades transthyretin and an inactive form of DJ-1 is secreted in familial amyloidotic polyneuropathy.
Dominant cardiac type of familial amyloidotic polyneuropathy associated with a novel transthyretin variant Thr59Arg.
Down regulation of a harmful variant protein by replacement of its normal protein.
Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model.
Early changes of nerve integrity in preclinical carriers of hereditary transthyretin Ala117Ser amyloidosis with polyneuropathy.
Early data on long-term efficacy and safety of inotersen in patients with hereditary transthyretin amyloidosis: a 2-year update from the open-label extension of the NEURO-TTR trial.
Early Data on Long-term Impact of Inotersen on Quality-of-Life in Patients with Hereditary Transthyretin Amyloidosis Polyneuropathy: Open-Label Extension of NEURO-TTR.
Early onset vitreous amyloidosis in familial amyloidotic polyneuropathy with a transthyretin Glu54Gly mutation is associated with elevated vitreous VEGF.
Effect of age and sex differences on wild-type transthyretin amyloid formation in familial amyloidotic polyneuropathy: a proteomic approach.
Effect of albumin on transthyretin and amyloidogenic transthyretin Val30Met disposition and tissue deposition in familial amyloidotic polyneuropathy.
Effect of liver trasplantation on familial amyloidotic polyneuropathy (FAP) and its limt.
Effect of nitric oxide in amyloid fibril formation on transthyretin-related amyloidosis.
Effect of orthotopic liver transplantation on the progression of familial amyloidotic polyneuropathy.
Effect of serum amyloid P component level on transthyretin-derived amyloid deposition in a transgenic mouse model of familial amyloidotic polyneuropathy.
Effect of sildenafil citrate (Viagra) on erectile dysfunction in a patient with familial amyloidotic polyneuropathy ATTR Val30Met.
Effect of tacrolimus and partial hepatectomy on transthyretin metabolism in rats.
Effect on disability and safety of Tafamidis in late onset of Met30 transthyretin familial amyloid polyneuropathy.
Electrically neutral microheterogeneity of human plasma transthyretin (prealbumin) detected by isoelectric focusing in urea gradients.
Electro-clinical presentation of hereditary transthyretin related amyloidosis when presenting as a polyneuropathy of unknown origin in northern France.
Elevated interleukin-6 levels are associated with impaired outcome in cardiac transthyretin amyloidosis.
Endoplasmic reticulum stress associated with extracellular aggregates. Evidence from transthyretin deposition in familial amyloid polyneuropathy.
Endothelium-dependent vasodilatation in patients with familial amyloidotic polyneuropathy.
Enzyme-linked immunosorbent assay of transthyretin devised for semimicro plasma diagnosis of familial amyloidotic polyneuropathy.
Epigallocatechin-3-gallate as a potential therapeutic drug for TTR-related amyloidosis: "in vivo" evidence from FAP mice models.
Evaluation of Mortality During Long-Term Treatment with Tafamidis for Transthyretin Amyloidosis with Polyneuropathy: Clinical Trial Results up to 8.5 Years.
Evaluation of tafamidis as first-line therapeutic agent for transthyretin familial amyloidotic polyneuropathy.
Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro.
Examination of the structure of the transthyretin amyloid fibril by image reconstruction from electron micrographs.
Exertional chest pain is sometimes more than just coronary atherosclerosis.
Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy.
Extracellular matrix markers for disease progression and follow-up of therapies in familial amyloid polyneuropathy V30M TTR-related.
Failure of Tafamidis to Halt Progression of Ala36Pro TTR Oculomeningovascular Amyloidosis.
Familial amyloid polyneuropathy.
Familial amyloidosis in a large Spanish kindred resulting from a D38V mutation in the transthyretin gene.
Familial amyloidosis with polyneuropathy associated with TTR Ser50Arg mutation.
Familial amyloidosis with polyneuropathy type 1 caused by transthyretin mutation Val50Met (Val30Met): 4 cases in a non-endemic area.
Familial amyloidotic polyneuropathy (ATTR Ser50Ile): the first autopsy case report.
Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders. 2nd International Symposium. Skelleftea, Sweden, June 1-3, 1992. Abstracts.
Familial amyloidotic polyneuropathy and transthyretin.
Familial amyloidotic polyneuropathy in Sweden: geographical distribution, age of onset, and prevalence.
Familial amyloidotic polyneuropathy presenting with carpal tunnel syndrome and a new transthyretin mutation, asparagine 70.
Familial amyloidotic polyneuropathy type 1 in Brazil is associated with the transthyretin Val30Met variant.
Familial Amyloidotic Polyneuropathy Type 1: A Hereditary Legacy.
Familial amyloidotic polyneuropathy type I with extracellular superoxide dismutase mutation: a case report.
Familial amyloidotic polyneuropathy with late-onset and well-preserved autonomic function: a Japanese kindred with novel mutant transthyretin (Ala97 to Gly).
Familial amyloidotic polyneuropathy with severe renal involvement in association with transthyretin Gly47Glu in Dutch, British and American-Finnish families.
Familial amyloidotic polyneuropathy without familial occurrence: carrier detection by the radioimmunoassay of variant transthyretin.
Familial amyloidotic polyneuropathy: a new transthyretin position 30 mutation (alanine for valine) in a family of German descent.
Familial Amyloidotic Polyneuropathy: domino liver transplantation.
Familial amyloidotic polyneuropathy: report of patients heterozygous for the transthyretin Gly42 gene.
Familial amyloidotic polyneuropathy: transthyretin (prealbumin) variants in kindreds of Italian origin.
Family studies of the genetic abnormality in transthyretin (prealbumin) in Portuguese patients with familial amyloidotic polyneuropathy.
FAP neuropathy and emerging treatments.
Fibril in senile systemic amyloidosis is derived from normal transthyretin.
Formation of cytotoxic transthyretin is not dependent on inter-molecular disulphide bridges commonly found within the amyloid form.
Gastrointestinal amyloidosis associated with transthyretin Phe64Ser mutation.
Gene therapy approach to FAP: in vivo influence of T119M in TTR deposition in a transgenic V30M mouse model.
Generation of familial amyloidotic polyneuropathy-specific induced pluripotent stem cells.
Generation of transgenic mice producing a human transthyretin variant: a possible mouse model for familial amyloidotic polyneuropathy.
Genetic analysis of familial amyloidotic polyneuropathy, an autosomal dominant disease.
Genetic anticipation in Portuguese kindreds with familial amyloidotic polyneuropathy is unlikely to be caused by triplet repeat expansions.
Genetic expression of a transthyretin mutation in a case of amyloidotic polyneuropathy occurring in an African.
Genetic expression of a transthyretin mutation in typical and late-onset Portuguese families with familial amyloidotic polyneuropathy.
Genetics of familial amyloidotic polyneuropathy in a Hong Kong Chinese kindred.
Glial cells in familial amyloidotic polyneuropathy.
hATTR Pathology: Nerve Biopsy Results from Italian Referral Centers.
Health-related quality of life in hereditary transthyretin amyloidosis polyneuropathy: a prospective, observational study.
Heart failure and cardiac involvement as isolated manifestation of familial form of transthyretin amyloidosis resulting from Val30Met mutation with no clinical signs of polyneuropathy.
Hereditary Amyloidosis with Recurrent Lung Infiltrates.
Hereditary transthyretin amyloidosis: a model of medical progress for a fatal disease.
Homozygosity for the met30 transthyretin gene in a Turkish kindred with familial amyloidotic polyneuropathy.
Homozygosity for the transthyretin-Met30 gene in three Japanese siblings with type I familial amyloidotic polyneuropathy.
Homozygosity for the transthyretin-Met30-gene in seven individuals with familial amyloidosis with polyneuropathy detected by restriction enzyme analysis of amplified genomic DNA sequences.
Human transthyretin (prealbumin) gene and molecular genetics of familial amyloidotic polyneuropathy.
Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease.
Iatrogenic amyloid neuropathy in a Japanese patient after sequential liver transplantation.
Identification of a new transthyretin variant (Ile49) in familial amyloidotic polyneuropathy using electrospray ionization mass spectrometry and nonisotopic RNase cleavage assay.
Identification of a novel transthyretin variant (Val30----Leu) associated with familial amyloidotic polyneuropathy.
Immunization in familial amyloidotic polyneuropathy: counteracting deposition by immunization with a Y78F TTR mutant.
Immunogenicity Assessment of Inotersen, a 2'-O-(2-Methoxyethyl) Antisense Oligonucleotide in Animals and Humans: Effect on Pharmacokinetics, Pharmacodynamics, and Safety.
Impact of antibodies against amyloidogenic transthyretin (ATTR) on phenotypes of patients with familial amyloidotic polyneuropathy (FAP) ATTR Valine30Methionine.
Impact of Non-Cardiac Clinicopathologic Characteristics on Survival in Transthyretin Amyloid Polyneuropathy.
Impact of serotonin transporter and catechol-O-methyl transferase genes polymorphism on gastrointestinal dysfunction in Swedish and Japanese familial amyloidotic polyneuropathy patients.
Impaired in vitro growth response of plasma-treated cardiomyocytes predicts poor outcome in patients with transthyretin amyloidosis.
Impairment of the ubiquitin-proteasome system associated with extracellular transthyretin aggregates in familial amyloidotic polyneuropathy.
Improvement of transthyretin familial amyloidotic polyneuropathy after liver transplantation in Argentinian patients.
In vitro inhibition of transthyretin aggregate-induced cytotoxicity by full and peptide derived forms of the soluble receptor for advanced glycation end products (RAGE).
In vitro modelling of familial amyloidotic polyneuropathy allows quantitative detection of transthyretin amyloid fibril-like structures in hepatic derivatives of patient-specific induced pluripotent stem cells.
In vivo detection of nerve injury in familial amyloid polyneuropathy by magnetic resonance neurography.
Incidence of nonamyloidogenic mutations in the transthyretin gene in patients with autonomic and small fiber neuropathy.
Indications for liver transplantation in patients with amyloidosis: a single-center experience with 11 cases.
Inotersen for the Treatment of Hereditary Transthyretin Amyloidosis.
Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis.
Inotersen: new promise for the treatment of hereditary transthyretin amyloidosis.
Interaction of the receptor for advanced glycation end products (RAGE) with transthyretin triggers nuclear transcription factor kB (NF-kB) activation.
Invention and Early History of Gapmers.
Investigation into thiol conjugation of transthyretin in hereditary transthyretin amyloidosis.
Iodination of salicylic acid improves its binding to transthyretin.
Japanese monozygotic twins with familial amyloidotic polyneuropathy (FAP) (ATTR Val30Met).
Kind and distribution of cutaneous sensation loss in hereditary transthyretin amyloidosis with polyneuropathy.
Kinetic analysis of the multistep aggregation pathway of human transthyretin.
Kinetic assay for high-throughput screening of in vitro transthyretin amyloid fibrillogenesis inhibitors.
Late-onset Familial Amyloidotic Polyneuropathy with Bence Jones Proteinuria and Cardiomyopathy.
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data.
Lipid droplets are present in amyloid deposits in familial amyloidotic polyneuropathy and dialysis related amyloidosis.
Liver transplantation and new therapeutic approaches for familial amyloidotic polyneuropathy (FAP).
Liver transplantation for familial amyloidotic polyneuropathy in Australia.
Liver transplantation in familial amyloidotic polyneuropathy. Follow-up of the first 20 Swedish patients.
Liver transplantation in transthyretin familial amyloid polyneuropathy: first report from Argentina.
Long-term effects of liver transplantation on small-fiber dysfunction in Japanese transthyretin (ATTR) V30M hereditary amyloidosis with polyneuropathy (FAP).
Long-term outcome of patients with hereditary transthyretin V30M amyloidosis with polyneuropathy after liver transplantation.
Long-term outcomes and complications of trabeculectomy for secondary glaucoma in patients with familial amyloidotic polyneuropathy.
Loss of functional albumin triggers acceleration of transthyretin amyloid fibril formation in familial amyloidotic polyneuropathy.
Lysozyme amyloidosis: report of 4 cases and a review of the literature.
Magnetization transfer ratio quantifies polyneuropathy in hereditary transthyretin amyloidosis.
Marked cardiomegaly in a patient with familial amyloidotic polyneuropathy after orthotopic liver transplantation: a case study.
Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis.
Methods to evaluate the inhibition of TTR fibrillogenesis induced by small ligands.
Misfolded transthyretin causes behavioral changes in a Drosophila model for transthyretin-associated amyloidosis.
Mitochondrial haplogroup is associated with the phenotype of familial amyloidosis with polyneuropathy in Swedish and French patients.
MMP-14 overexpression correlates with the neurodegenerative process in familial amyloidotic polyneuropathy.
mNIS+7 and lower limb function in inotersen treatment of hereditary transthyretin-mediated amyloidosis.
Modifications of transthyretin in amyloid fibrils: analysis of amyloid from homozygous and heterozygous individuals with the Met30 mutation.
Molecular diagnosis of transthyretin Met30 mutation in an Italian family with familial amyloidotic polyneuropathy.
Nerve ultrasonography features in hereditary transthyretin amyloidosis with V30M mutation and polyneuropathy.
Nerve ultrasonography findings as possible pitfall in differential diagnosis between hereditary transthyretin amyloidosis with polyneuropathy and chronic inflammatory demyelinating polyneuropathy.
Nerve Ultrasound Comparison Between Transthyretin Familial Amyloid Polyneuropathy and Chronic Inflammatory Demyelinating Polyneuropathy.
Neurofilament light chain, a biomarker for polyneuropathy in systemic amyloidosis.
Neuroradiologic and clinicopathologic features of oculoleptomeningeal type amyloidosis.
New mutant gene (transthyretin Arg 58) in cases with hereditary polyneuropathy detected by non-isotope method of single-strand conformation polymorphism analysis.
New structural information and update on liver transplantation in transthyretin-associated amyloidosis. Report from the 4th International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Related Disorders & the 3rd International Workshop on Liver Transplantation in Familial Amyloid Polyneuropathy, Umeå Sweden, June 1999.
New transthyretin variants SER 91 and SER 116 associated with familial amyloidotic polyneuropathy. Mutations in brief no. 151. Online.
Novel Antibody for the Treatment of Transthyretin Amyloidosis.
Novel methods for detecting amyloidogenic proteins in transthyretin related amyloidosis.
Ocular amyloid angiopathy associated with familial amyloidotic polyneuropathy caused by amyloidogenic transthyretin Y114C.
Ocular microangiopathy in familial amyloidotic polyneuropathy, type I.
Orthotopic liver transplantation for familial amyloidotic polyneuropathy: a pathological study.
Outcome of exercise electrocardiography in familial amyloidotic polyneuropathy patients, Portuguese type, under evaluation for liver transplantation.
Outcome of liver transplantation for familial amyloidotic polyneuropathy.
Outcome of liver transplantation for transthyretin amyloidosis: follow-up of Japanese familial amyloidotic polyneuropathy patients.
Outcomes of domino liver transplantation: a single institution's experience.
Overexpression of Protocadherin-10 in Transthyretin-Related Familial Amyloidotic Polyneuropathy.
Pathological changes long after liver transplantation in a familial amyloidotic polyneuropathy patient.
Pathology of familial amyloidotic polyneuropathy with TTR met 30 in Kumamoto, Japan.
Patient and family experience with transthyretin amyloid cardiomyopathy (ATTR-CM) and polyneuropathy (ATTR-PN) amyloidosis: results of two focus groups.
Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.
Polyacrylamide gel electrophoresis followed by sodium dodecyl sulfate gradient polyacrylamide gel electrophoresis for the study of the dimer to monomer transition of human transthyretin.
Polymeric monolithic microcartridges with gold nanoparticles for the analysis of protein biomarkers by on-line solid-phase extraction capillary electrophoresis-mass spectrometry.
Population Pharmacokinetic-Pharmacodynamic Modeling of Inotersen, an Antisense Oligonucleotide for Treatment of Patients with Hereditary Transthyretin Amyloidosis.
Potential treatment of transthyretin-type amyloidoses by sulfite.
Potential use of glucuronylglucosyl-?-cyclodextrin as a novel therapeutic tool for familial amyloidotic polyneuropathy.
Potential use of glucuronylglucosyl-?-cyclodextrin/dendrimer conjugate (G2) as a siRNA carrier for the treatment of familial amyloidotic polyneuropathy.
Potential use of lactosylated dendrimer (G3)/?-cyclodextrin conjugates as hepatocyte-specific siRNA carriers for the treatment of familial amyloidotic polyneuropathy.
Preimplantation genetic diagnosis for familial amyloidotic polyneuropathy (FAP).
Prenatal diagnosis of familial amyloidotic polyneuropathy: evidence for an early expression of the associated transthyretin methionine 30.
Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions.
Presence of a plasma transthyretin (prealbumin) variant in familial amyloidotic polyneuropathy in a kindred of Greek origin.
Presence of an abnormal transthyretin (prealbumin) in Portuguese patients with familial amyloidotic polyneuropathy.
Presence of N-glycosylated transthyretin in plasma of V30M carriers in familial amyloidotic polyneuropathy: an escape from ERAD.
Presence of variant transthyretin in aqueous humor of a patient with familial amyloidotic polyneuropathy after liver transplantation.
Prevalence of hereditary transthyretin amyloid polyneuropathy in idiopathic progressive neuropathy in conurban areas.
Production and functional analysis of normal and variant recombinant human transthyretin proteins.
Production of recombinant human transthyretin with biological activities toward the understanding of the molecular basis of familial amyloidotic polyneuropathy (FAP).
Progression of cardiomyopathy and neuropathy after liver transplantation in a patient with familial amyloidotic polyneuropathy caused by tyrosine-77 transthyretin variant.
Progressive brachial plexus enlargement in hereditary transthyretin amyloidosis.
Proline at position 36: a new transthyretin mutation associated with familial amyloidotic polyneuropathy.
Protective role of anakinra against transthyretin-mediated axonal loss and cell death in a mouse model of familial amyloidotic polyneuropathy.
Psychosocial impact of presymptomatic genetic testing for transthyretin amyloidotic polyneuropathy.
Q-Rich Yeast Prion [
Quantified sensory abnormalities in early genetically verified transthyretin amyloid polyneuropathy.
Quantitative analysis of amyloid fibril protein in systemic organs of patients with familial amyloidotic polyneuropathy.
Quantitative analysis of post-translational modifications in human serum transthyretin associated with familial amyloidotic polyneuropathy by targeted LC-MS and intact protein MS.
Quantitative sensation and autonomic test abnormalities in transthyretin amyloidosis polyneuropathy.
Quantitative sudomotor test helps differentiate transthyretin familial amyloid polyneuropathy from chronic inflammatory demyelinating polyneuropathy.
Rapid method to characterize mutations in transthyretin in cerebrospinal fluid from familial amyloidotic polyneuropathy patients by use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Rate of neuropathic progression in hereditary transthyretin amyloidosis with polyneuropathy and other peripheral neuropathies: a systematic review and meta-analysis.
RE-INTERVENTION IN DE NOVO VITREOUS OPACITIES AFTER PARS PLANA VITRECTOMY IN FAMILIAL AMYLOIDOTIC POLYNEUROPATHY TTR VAL30METPORTUGUESE PATIENTS.
Real-world outcomes in non-endemic hereditary transthyretin amyloidosis with polyneuropathy: a 20-year German single-referral centre experience.
Recent Advances in Oligonucleotide-Based Therapy for Transthyretin Amyloidosis: Clinical Impact and Future Prospects.
Recent advances in transthyretin amyloidosis therapy.
Recurrent syncope as persistently isolated feature of transthyretin amyloidotic polyneuropathy.
Red flags in patients with hereditary transthyretin amyloidosis at diagnosis in a non-endemic area of Spain.
Regional difference and similarity of familial amyloidosis with polyneuropathy in France.
Relationship between amyloid deposition and intracellular structural changes in familial amyloidotic polyneuropathy.
Report from the Familial Amyloidotic Polyneuropathy World Transplant Registry (FAPWTR) and the Domino Liver Transplant Registry (DLTR).
Responder analysis for neuropathic impairment and quality-of-life assessment in patients with hereditary transthyretin amyloidosis with polyneuropathy in the NEURO-TTR study.
Restriction fragment analysis confirms the position 33 mutation in transthyretin from an Israeli patient (SKO) with familial amyloidotic polyneuropathy.
Role of VLDL/chylomicron in amyloid formation in familial amyloidotic polyneuropathy.
Safety and efficacy of long-term diflunisal administration in hereditary transthyretin (ATTR) amyloidosis.
Scavenger treatment of free radical injury in familial amyloidotic polyneuropathy: a study on Swedish transplanted and non-transplanted patients.
Schwann cells contribute to neurodegeneration in transthyretin amyloidosis.
Secondary glaucoma in patients with familial amyloidotic polyneuropathy.
SELDI-TOF Mass Spectrometry Evaluation of Variant Transthyretins for Diagnosis and Pathogenesis of Familial Amyloidotic Polyneuropathy.
Selective binding to transthyretin and tetramer stabilization in serum from patients with familial amyloidotic polyneuropathy by an iodinated diflunisal derivative.
Selective silencing of a mutant transthyretin allele by small interfering RNAs.
Serum transthyretin levels in senile systemic amyloidosis: effects of age, gender and ethnicity.
Serum transthyretin levels in Swedish TTR V30M carriers.
Severe congestive heart failure with cardiac liver cirrhosis 10 years after orthotopic liver transplantation for familial amyloidotic polyneuropathy.
Simple detection of abnormal serum transthyretin from patients with familial amyloidotic polyneuropathy by high-performance liquid chromatography/electrospray ionization mass spectrometry using material precipitated with specific antiserum.
Simplified method for screening populations at risk for transthyretin Met30-associated familial amyloidotic polyneuropathy.
Small transthyretin (TTR) ligands as possible therapeutic agents in TTR amyloidoses.
Societal costs and burden of hereditary transthyretin amyloidosis polyneuropathy.
Somatic mosaicism with reversion to normality of a mutated transthyretin allele related to a familial amyloidotic polyneuropathy.
Specific Disruption of Transthyretin(105-115) Fibrilization Using "Stabilizing" Inhibitors of Transthyretin Amyloidogenesis.
Specific removal of transthyretin from plasma of patients with familial amyloidotic polyneuropathy: optimization of an immunoadsorption procedure.
Structural distribution of mutations associated with familial amyloidotic polyneuropathy in human transthyretin.
Structural insight to mutated Y116S transthyretin by molecular dynamics simulation.
Structural insights into a zinc-dependent pathway leading to Leu55Pro transthyretin amyloid fibrils.
Structurally abnormal transthyretin causing familial amyloidotic polyneuropathy in Sweden.
Structure of Met30 variant of transthyretin and its amyloidogenic implications.
Studies on plasma transthyretin (prealbumin) in familial amyloidotic polyneuropathy, Portuguese type.
Study of an anti-human transthyretin immunoadsorbent. Influence of coupling chemistry on binding capacity and ligand leakage.
Sulfite and base for the treatment of familial amyloidotic polyneuropathy: two additive approaches to stabilize the conformation of human amyloidogenic transthyretin.
Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides.
Suppression of transthyretin expression by ribozymes: a possible therapy for familial amyloidotic polyneuropathy.
Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous beta-sheet helix.
Synergy of combined doxycycline/TUDCA treatment in lowering Transthyretin deposition and associated biomarkers: studies in FAP mouse models.
Synthesis of an analog of the thyroid hormone-binding protein transthyretin via regioselective chemical ligation.
Systemic amyloidosis in transgenic mice carrying the human mutant transthyretin (Met 30) gene. Pathological and immunohistochemical similarity to human familial amyloidotic polyneuropathy, type I.
Systemic amyloidosis in transgenic mice carrying the human mutant transthyretin (Met30) gene. Pathologic similarity to human familial amyloidotic polyneuropathy, type I.
Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/?-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy.
Tafamidis, a Noninvasive Therapy for Delaying Transthyretin Familial Amyloid Polyneuropathy: Systematic Review and Meta-Analysis.
Tafamidis.
Tafamidis: A Review in Transthyretin Amyloidosis with Polyneuropathy.
Tafamidis: a review of its use in familial amyloid polyneuropathy.
Targeting a rare amyloidotic disease through rationally designed polymer conjugates.
Tertiary structures of amyloidogenic and non-amyloidogenic transthyretin variants: new model for amyloid fibril formation.
Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer.
Tetraparesis and sensorimotor axonal polyneuropathy due to co-occurrence of Pompe disease and hereditary ATTR amyloidosis.
The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution.
The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin.
The crystal structure of amyloidogenic Leu55 --> Pro transthyretin variant reveals a possible pathway for transthyretin polymerization into amyloid fibrils.
The crystal structure of transthyretin from chicken.
The Extracellular Protein, Transthyretin Is an Oxidative Stress Biomarker.
The flavonoid luteolin, but not luteolin-7-O-glucoside, prevents a transthyretin mediated toxic response.
The high frequency of TTR M30 in familial amyloidotic polyneuropathy is not due to a founder effect.
The impact of clinical heterogeneity on conducting network meta-analyses in transthyretin amyloidosis with polyneuropathy.
The impact of V30A mutation on transthyretin protein structural stability and cytotoxicity against neuroblastoma cells.
The Italian neuromuscular registry: a coordinated platform where patient organizations and clinicians collaborate for data collection and multiple usage.
The transmissible amyloidoses: genetical control of spontaneous generation of infectious amyloid proteins by nucleation of configurational change in host precursors: kuru-CJD-GSS-scrapie-BSE.
Tissue remodeling after interference RNA mediated knockdown of transthyretin in a familial amyloidotic polyneuropathy mouse model.
Transgenic mouse model of familial amyloidotic polyneuropathy.
Transthyretin (prealbumin) in familial amyloidotic polyneuropathy: genetic and functional aspects.
Transthyretin ALA 71: a new transthyretin variant in a Spanish family with familial amyloidotic polyneuropathy.
Transthyretin Ala97Ser is associated with familial amyloidotic polyneuropathy in a Chinese-Taiwanese family.
Transthyretin Amyloid Cardiomyopathy-Current and Future Therapies.
Transthyretin Amyloid Goiter in a Renal Allograft Recipient.
Transthyretin amyloid polyneuropathies mimicking a demyelinating polyneuropathy.
Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of De Novo generation of Creutzfeldt-Jakob disease infectious amyloid by a spontaneous change in configuration of the host precursor protein.
Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of spontaneous generation of infectious amyloids by patterned configurational change in host precursors in Creutzfeldt-Jacob disease.
Transthyretin amyloidosis: an under-recognized neuropathy and cardiomyopathy.
Transthyretin and familial amyloidotic polyneuropathy.
Transthyretin and familial amyloidotic polyneuropathy. Recent progress in understanding the molecular mechanism of neurodegeneration.
Transthyretin deposition in familial amyloidotic polyneuropathy.
Transthyretin familial amyloid polyneuropathy (TTR-FAP): Parameters for early diagnosis.
Transthyretin familial amyloid polyneuropathy due to lle107Val mutation mimicking atypical chronic inflammatory demyelinating polyneuropathy: case report.
Transthyretin familial amyloidotic polyneuropathy: histopathological study of the explanted livers.
Transthyretin fibrillogenesis entails the assembly of monomers: a molecular model for in vitro assembled transthyretin amyloid-like fibrils.
Transthyretin forms amyloid fibrils at physiological pH with ultrasonication.
Transthyretin Ile73Val is associated with familial amyloidotic polyneuropathy in a Bangladeshi family. Mutations in brief no. 158. Online.
Transthyretin is not expressed by dorsal root ganglia cells.
Transthyretin oligomers induce calcium influx via voltage-gated calcium channels.
Transthyretin Pro 36 associated with familial amyloidotic polyneuropathy in an Ashkenazic Jewish kindred.
Transthyretin proteins regulate angiogenesis by conferring different molecular identities to endothelial cells.
Transthyretin related familial amyloid polyneuropathy.
Transthyretin RNA profiling in livers from transplanted patients affected by familial amyloidotic polyneuropathy, and identification of a dual transcription start point.
Transthyretin synthesis in rabbit ciliary pigment epithelium.
Transthyretin Thr60Ala Appalachian-type mutation in a Japanese family with familial amyloidotic polyneuropathy.
TRANSTHYRETIN V30M FAMILIAL AMYLOIDOSIS PRESENTING AS ISOLATED RETINAL ANGIOPATHY.
Transthyretin Val71Ala mutation in a Dutch family with familial amyloidotic polyneuropathy.
Transthyretin valine-94-alanine, a novel variant associated with late-onset systemic amyloidosis with cardiac involvement.
Transthyretin-related familial amyloidotic polyneuropathy-Progress in Kumamoto, Japan (1967-2010)-.
TTR-familial amyloid polyneuropathy--neurological aspects.
TTR-related amyloid neuropathy: clinical, electrophysiological and pathological findings in 15 unrelated patients.
Two novel variants of transthyretin identified in Japanese cases with familial amyloidotic polyneuropathy: transthyretin (Glu42 to Gly) and transthyretin (Ser50 to Arg).
Two transthyretin mutations (glu42gly, his90asn) in an Italian family with amyloidosis.
Two-tiered DNA-based diagnosis of transthyretin amyloidosis reveals two novel point mutations.
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.
Understanding the Disease Course and Therapeutic Benefit of Tafamidis Across Real-World Studies of Hereditary Transthyretin Amyloidosis with Polyneuropathy: A Proof of Concept for Integrative Data Analytic Approaches.
Unusual self-association properties of transthyretin Y114C related to familial amyloidotic polyneuropathy: effects on detection and quantification.
Uptake of aggregating transthyretin by fat body in a Drosophila model for TTR-associated amyloidosis.
Use of Drugs for ATTRv Amyloidosis in the Real World: How Therapy Is Changing Survival in a Non-Endemic Area.
Variable Presentation of Hereditary Transthyretin-Mediated Amyloidosis at a Single Center.
Variant transthyretin in cerebrospinal fluid in familial amyloidotic polyneuropathy.
VIth International Symposium on Familial Amyloidotic Polyneuropathy and Other Transthyretin Disorders and the Vth International Workshop on Liver Transplantation in Familial Amyloidotic Polyneuropathy 24-26 August 2005 La Jolla, CA, USA.
Vitreous amyloidosis associated with homozygosity for the transthyretin methionine-30 gene.
Vitreous amyloidosis in familial amyloidotic polyneuropathy. Report of a case with the Val30Met transthyretin mutation.
Vitreous amyloidosis in two sisters as the indication of transthyretin-related familial form of systemic amyloidosis among liver transplantation candidates.
Vitreous amyloidosis without systemic or familial involvement.
Vitreous opacities in a case of familial amyloidotic polyneuropathy associated with a transthyretin Lys 54.
Wild-type transthyretin-derived amyloidosis in various ligaments and tendons.
X-ray absorption spectroscopy reveals a substantial increase of sulfur oxidation in transthyretin (TTR) upon fibrillization.
[A late onset familial amyloidotic polyneuropathy (FAP) with a novel variant transthyretin characterized by a basic-for-acidic amino acid substitution (Glu61-->Lys)]
[Amyloidogenesis of variant transthyretin in familial amyloidotic polyneuropathy]
[Amyloidosis and neurological disorders: Treatable amyloidosis].
[An immunocytochemical study of alpha 1-antichymotrypsin in the senescent cerebral amyloid]
[Application to transthyretin analysis]
[Biochemical studies of amyloidogenesis in two different types of amyloidoses--amyloid transthyretin variant in familial amyloidotic polyneuropathy and islet amyloid polypeptide in non-insulin-dependent diabetes mellitus]
[Case report; The first transthyretin Thr49Ala variant case of familial amyloidotic polyneuropathy in Japan].
[Clinical and genetic heterogeneity in familial amyloidotic polyneuropathy associated with variant transthyretin]
[Clinical characteristics of Hungarian-type familial meningo-cerebrovascular amyloidosis]
[Familial amyloidotic polyneuropathy with a transthyretin variant (Val30-->Leu)]
[Familial amyloidotic polyneuropathy without familial occurrence but with asymptomatic carriers discovered by radioimmunoassay of variant transthyretin]
[Gene therapy in familial amyloidotic polyneuropathy by single-stranded oligonucleotides (SSOs)]
[Hereditary transthyretin amyloidosis].
[Liver disease recurrence after liver transplantation]
[Liver transplantation in familial amyloid polyneuropathy. Case report and review of the literature]
[Myocardiopathy caused by Portuguese-type familial amyloidotic polyneuropathy. Sequential morphologic and functional study of 60 patients]
[Novel tool for diagnosis of amyloidosis]
[Prenatal diagnosis of familial amyloidotic polyneuropathy]
[Protein and DNA sequencing analyses of transthyretin in familial amyloidotic polyneuropathy]
[Review of the recent literature on peripheral neuropathies: therapeutic advances].
[The importance of TTR met 30 in the diagnosis of familial amyloidotic polyneuropathy in the absence of a positive family history]
[The use of FD-6 monoclonal antibody in diagnosing and detecting the carriers of familial amyloidotic polyneuropathy type I]
[Transthyretin familial amyloid polyneuropathy - three Hungarian cases with rare mutations (His88Arg and Phe33Leu)].
[Two brother cases of late-onset familial amyloidotic polyneuropathy in Kyoto]
[What gnaws at the heart and gets on the nerves].
Polyradiculoneuropathy
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
Analyses of transthyretin concentration in the cerebrospinal fluid of patients with Guillain-Barré syndrome and other neurological disorders.
Candidate biomarkers of chronic inflammatory demyelinating polyneuropathy (CIDP): proteome analysis of cerebrospinal fluid.
Hard to swallow: atypical transthyretin amyloid neuropathy mistaken for CIDP.
Porphyrias
Unusual Pain Disorders - What Can Be Learned from Them?
Porphyrias, Hepatic
Development of siRNA Therapeutics for the Treatment of Liver Diseases.
Pre-Eclampsia
Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia.
An altered pattern of circulating apolipoprotein E3 isoforms is implicated in preeclampsia.
Human placental transthyretin in fetal growth restriction in combination with preeclampsia and the HELLP syndrome.
MicroRNA regulation of transthyretin in trophoblast biofunction and preeclampsia.
Multifactorial Analysis of Affinity-Mass Spectrometry Data from Serum Protein Samples: A Strategy to Distinguish Patients with Preeclampsia from Matching Control Individuals.
Oxidized transthyretin in amniotic fluid as an early marker of preeclampsia.
Preeclampsia is associated with low placental transthyretin levels.
Transthyretin as a novel candidate biomarker for preeclampsia.
Transthyretin Is Dysregulated in Preeclampsia, and Its Native Form Prevents the Onset of Disease in a Preclinical Mouse Model.
Pressure Ulcer
Inflammation and disability as risk factors for mortality in elderly acute care patients.
Primary Dysautonomias
6MWT performance correlates with peripheral neuropathy but not with cardiac involvement in patients with hereditary transthyretin amyloidosis (hATTR).
Cardiac Dysautonomia and Survival in Hereditary Transthyretin Amyloidosis.
Cardiac Dysautonomia Predicts Long-Term Survival in Hereditary Transthyretin Amyloidosis After Liver Transplantation.
Circulating microRNAs Profile in Patients With Transthyretin Variant Amyloidosis.
Prion Diseases
Benefit of doxycycline treatment on articular disability caused by dialysis related amyloidosis.
The Ultrastructure of Tissue Damage by Amyloid Fibrils.
Prostatic Hyperplasia
Identification of potential complementary serum biomarkers to differentiate prostate cancer from benign prostatic hyperplasia using gel- and lectin-based proteomics analyses.
Prostatic Neoplasms
Changes of transthyretin and clusterin after androgen ablation therapy and correlation with prostate cancer malignancy.
Tetraiodothyroacetic acid and transthyretin silencing inhibit pro-metastatic effect of L-thyroxin in anoikis-resistant prostate cancer cells through regulation of MAPK/ERK pathway.
Protein Deficiency
Expression of liver-specific genes coding for plasma proteins in protein deficiency.
Protein-Energy Malnutrition
Chemical pathology of homocysteine. V. Thioretinamide, thioretinaco, and cystathionine synthase function in degenerative diseases.
Low levels of plasma proteins: malnutrition or inflammation?
Plasma levels of transthyretin and retinol-binding protein in Child-A cirrhotic patients in relation to protein-calorie status and plasma amino acids, zinc, vitamin A and plasma thyroid hormones.
Repletion of the plasma pool of nutrient transport proteins occurs at different rates during the nutritional rehabilitation of severely malnourished children.
Structural modifications of serum transthyretin in rats during protein-energy malnutrition.
Value of serum transthyretin measurements in the assessment of marginal protein-energy malnutrition in rats.
Proteinuria
Albumin/creatinine (uACR) and protein/creatinine (uPCR) ratios in spot urine samples can be used to evaluate albuminuria and proteinuria in hereditary transthyretin amyloidosis patients.
Clinical associations of an increased transthyretin band in routine serum and urine protein electrophoresis.
Transthyretin Is Dysregulated in Preeclampsia, and Its Native Form Prevents the Onset of Disease in a Preclinical Mouse Model.
Proteostasis Deficiencies
Impact of Genetic Testing in Transthyretin (ATTR) Cardiac Amyloidosis.
Mechanisms of transthyretin cardiomyocyte toxicity inhibition by resveratrol analogs.
Native state kinetic stabilization as a strategy to ameliorate protein misfolding diseases: a focus on the transthyretin amyloidoses.
Structural Stabilization of Human Transthyretin by Centella asiatica (L.) Urban Extract: Implications for TTR Amyloidosis.
The proteome response to amyloid protein expression in vivo.
Pulmonary Disease, Chronic Obstructive
Nutritional depletion in patients on long-term oxygen therapy and/or home mechanical ventilation.
Transthyretin--an explanation of "anomalous" serum thyroid hormone values in severe illness?
Pyometra
The plasma proteome and the acute phase protein response in canine pyometra.
Renal Insufficiency
Metabolism and clinical interest of serum transthyretin (prealbumin) in dialysis patients.
Metabolomics analysis for diagnosis and biomarker discovery of transthyretin amyloidosis.
[Amyloid from insulin treatment: a pitfall for the pathologist and the diabetologist].
Renal Insufficiency, Chronic
Human TTRV30M localization within podocytes in a transgenic mouse model of transthyretin related amyloidosis: does the environment play a role?
Respiratory Insufficiency
Nutritional depletion in patients on long-term oxygen therapy and/or home mechanical ventilation.
Retinal Vein Occlusion
Intravitreal bevacizumab upregulates transthyretin in experimental branch retinal vein occlusion.
Rhabdomyolysis
Rhabdomyolysis in the Setting of Concomitant Use of Tafamidis, Atorvastatin, and Amiodarone.
Sarcoidosis
A quantitative proteomic analysis of soluble bronchoalveolar fluid proteins from patients with sarcoidosis and chronic beryllium disease.
Small fiber neuropathy: Diagnosis, causes, and treatment.
Sarcoma, Avian
Optimized AAV-protein phosphatase 5 helper-viruses for efficient liver transduction by single-stranded AAV vectors: Therapeutic expression of Factor IX at reduced vector doses.
Sarcopenia
A proposed nomenclature and diagnostic criteria for protein-energy wasting in acute and chronic kidney disease.
Assessment of body protein: energy status in chronic kidney disease.
Plasma Transthyretin as A Biomarker of Sarcopenia in Elderly Subjects.
Schistosomiasis
Protein C deficiency in the compensated form of hepatosplenic schistosomiasis.
Scrapie
Amyloidosis.
Molecular biology of brain aging and neurodegenerative disorders.
Scurvy
Scurvy in hospitalized elderly patients.
Seizures
Effects of Chronic Stress on Prefrontal Cortex Transcriptome in Mice Displaying Different Genetic Backgrounds.
Oculoleptomeningeal amyloidosis in a patient with a TTR Val30Gly mutation in the transthyretin gene.
Peony root extract upregulates transthyretin and phosphoglycerate mutase in mouse cobalt focus seizure.
Recurrent subarachnoid hemorrhage associated with a new transthyretin variant (Gly53Glu).
Sepsis
Continuous evaluation of changes in the serum proteome from early to late stages of sepsis caused by Klebsiella pneumoniae.
Measurement of granulocyte maturation may improve the early diagnosis of the septic state.
Serum transthyretin levels in patients with burn injury.
Shock, Cardiogenic
Characterization of untyped cardiac amyloidosis by mass spectrometry in a patient with Gly6Ser transthyretin polymorphism in fatal cardiogenic shock.
Siderosis
Failure of Tafamidis to Halt Progression of Ala36Pro TTR Oculomeningovascular Amyloidosis.
Familial amyloid polyneuropathy involving a homozygous Val30Met mutation in the amyloidogenic transthyretin gene presenting with superficial siderosis: a case report.
Familial leptomeningeal amyloidosis with a transthyretin variant Asp18Gly representing repeated subarachnoid haemorrhages with superficial siderosis.
Transthyretin amyloidosis and superficial siderosis of the CNS.
Sigmoid Neoplasms
Significant deposition of wild type transthyretin-derived amyloid in the gastrointestinal tract of aged individuals.
Silicosis
[Utilizing 2-DE and MALDI-TOF MS/MS to screen differentially expressed serum proteins of silicosis]
Small Fiber Neuropathy
Electro-clinical presentation of hereditary transthyretin related amyloidosis when presenting as a polyneuropathy of unknown origin in northern France.
Incidence of nonamyloidogenic mutations in the transthyretin gene in patients with autonomic and small fiber neuropathy.
Potential Role of In Vivo Confocal Microscopy for Imaging Corneal Nerves in Transthyretin Familial Amyloid Polyneuropathy.
Small fiber neuropathy in Sjögren syndrome: Comparison with other small fiber neuropathies.
Smoldering Multiple Myeloma
Coexistent transthyretin amyloid cardiomyopathy and monoclonal gammopathy: Diagnostic challenges and prognostic implications.
Pilot Study of F18-Florbetapir in the Early Evaluation of Cardiac Amyloidosis.
Spinal Cord Diseases
Recurrent subarachnoid hemorrhage associated with a new transthyretin variant (Gly53Glu).
Spinal Stenosis
Increased thickness of lumbar spine ligamentum flavum in wild-type transthyretin amyloidosis.
Lumbar ligamentum flavum burden: Evaluating the role of ATTRwt amyloid deposition in ligamentum flavum thickness at all lumbar levels.
Lumbosacral stenosis in Labrador retriever military working dogs - an exomic exploratory study.
Spinal Stenosis in Familial Transthyretin Amyloidosis.
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis.
Spinocerebellar Ataxias
Coexistence of familial transthyretin amyloidosis ATTR Val30Met and spinocerebellar ataxia type 1 in a Japanese family--a follow-up autopsy report.
Spinocerebellar Degenerations
Twenty Years of a Pre-Symptomatic Testing Protocol for Late-Onset Neurological Diseases in Portugal.
Spondylarthropathies
Early destructive spondyloarthropathy from combined beta2-microglobulin and transthyretin Met30 amyloidosis in a dialysed patient.
Squamous Cell Carcinoma of Head and Neck
Analysis of the saliva proteome from patients with head and neck squamous cell carcinoma reveals differences in abundance levels of proteins associated with tumour progression and metastasis.
ST Elevation Myocardial Infarction
Plasma Exosome Profile in ST-Elevation Myocardial Infarction Patients with and without Out-of-Hospital Cardiac Arrest.
Starvation
Pretreatment of starved rats with ornithine alpha-ketoglutarate: effects on hepatic mRNA levels and plasma concentrations of three liver-secreted proteins.
Stomach Neoplasms
Diagnostic value of apolipoprotein C-I, transthyretin and apolipoprotein C-III in gastric cancer.
Serum transthyretin level is associated with prognosis of patients with gastric cancer.
[Use of serum protein profiling for early diagnosis of gastric cancer.]
Stroke
Acute-phase proteins before cerebral ischemia in stroke-prone rats: identification by proteomics.
Quick and effective improvement of leucine enriched dietary supplement on malnutrition in acute stroke patients receiving enteral tube feeding.
Transthyretin Concentrations in Acute Stroke Patients Predict Convalescent Rehabilitation.
Transthyretin expression in the postischemic brain.
Strongyloidiasis
Shotgun proteomics of Strongyloides venezuelensis infective third stage larvae: Insights into host-parasite interaction and novel targets for diagnostics.
Subarachnoid Hemorrhage
Recurrent subarachnoid hemorrhage associated with a new transthyretin variant (Gly53Glu).
Syncope
Cardiac amyloidosis associated with a novel transthyretin aspartic acid-18 glutamic acid de novo mutation.
Recurrent syncope as persistently isolated feature of transthyretin amyloidotic polyneuropathy.
Syncope as a Phenotypic Expression of Hereditary Transthyretin Amyloidosis Val142Ile (Val122Ile).
Tenosynovitis
The Tenosynovitis of Fingers Associated with Transthyretin Amyloidosis.
Teratocarcinoma
Induction of the expression of retinol-binding protein and transthyretin in F9 embryonal carcinoma cells differentiated to embryoid bodies.
Thrombocytopenia
Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia.
Thrombosis
No Association Between CHADS-VASc Score and Left Atrial Appendage Thrombus in Patients With Transthyretin Amyloidosis.
Stroke risk and atrial mechanical dysfunction in cardiac amyloidosis.
Thyrotoxicosis
A new family with hyperthyroxinemia caused by transthyretin Val109 misdiagnosed as thyrotoxicosis and resistance to thyroid hormone--a clinical research center study.
Isoelectric focussing of human thyroxine binding globulin (thyropexin) and human prealbumin (transthyretin).
Trisomy 18 Syndrome
Molecular analysis of the expression of transthyretin in intestine and liver from trisomy 18 fetuses.
Typhoid Fever
Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis.
Urinary Bladder Neoplasms
Transthyretin in bladder cancer.
Uterine Cervical Neoplasms
Identification of potential cervical cancer serum biomarkers in Thai patients.
Uveitis
Vitreous amyloidosis with autonomic neuropathy of the digestive tract associated with a novel transthyretin p.Gly87Arg variant in a Bangladeshi patient: a case report.
Vascular Diseases
Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy.
ProApolipoprotein A1: a serum marker of brain metastases in lung cancer patients.
Vasculitis, Central Nervous System
Transthyretin amyloid-related cerebral angiitis after liver transplantation.
Ventricular Dysfunction, Left
Speckle Tracking and Transthyretin Amyloid Cardiomyopathy.
Virus Diseases
[Transthyretin levels in serum and cerebrospinal fluid sustain the nutrio-viral hypothesis of the Cuban epidemic neuropathy]
Vitamin A Deficiency
A low molar ratio of retinol binding protein to transthyretin indicates vitamin A deficiency during inflammation: studies in rats and a posterior analysis of vitamin A-supplemented children with measles.
Proxy markers of serum retinol concentration, used alone and in combination, to assess population vitamin A status in Kenyan children: a cross-sectional study.
Vitreoretinopathy, Proliferative
[Differential expression and significance of complement C4b and transthyretin in proliferative vitreoretinopathy].
Waldenstrom Macroglobulinemia
Amyloid and peripheral nervous system disease.
Paraproteinemias and Peripheral Nerve Disease.
True, true unrelated? Coexistence of Waldenström macroglobulinemia and cardiac transthyretin amyloidosis.
Wasting Syndrome
Parenteral nutrition improves nutritional status, autonomic symptoms and quality of life in transthyretin amyloid polyneuropathy.