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Disease on EC 3.2.1.14 - chitinase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
Assay for Assessing Mucin Binding to Bacteria and Bacterial Proteins.
Crystallization and preliminary X-ray analysis of a chitinase from the fungal pathogen Coccidioides immitis.
Acute Coronary Syndrome
Serum Chitotriosidase Activity in Acute Coronary Syndrome.
Acute Kidney Injury
Diagnosis of cardiac surgery-associated acute kidney injury: differential roles of creatinine, chitinase 3-like protein 1 and neutrophil gelatinase-associated lipocalin: a prospective cohort study.
Urinary cell cycle arrest biomarkers and chitinase 3-like protein 1 (CHI3L1) to detect acute kidney injury in the critically ill: a post hoc laboratory analysis on the FINNAKI cohort.
Urinary chitinase 3-like protein 1 for early diagnosis of acute kidney injury: a prospective cohort study in adult critically ill patients.
Urine YKL-40 is associated with progressive acute kidney injury or death in hospitalized patients.
Adenocarcinoma
Effect of antifreeze proteins on frozen primary prostatic adenocarcinoma cells.
SI-CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor-associated macrophages.
Adenoma
Molecular pathology of murine ureteritis causing obstructive uropathy with hydronephrosis.
Adrenoleukodystrophy
Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy.
Airway Obstruction
Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease.
The activity and expression of chitinase in the equine lung and its activity in normal horses and animals with recurrent airway obstruction.
Alagille Syndrome
The expanding spectrum of disorders with elevated plasma chitotriosidase activity: an update.
Albuminuria
Changes in glycosylation of human blood plasma chitotriosidase in patients with type 2 diabetes.
Alzheimer Disease
Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients.
Cerebrospinal fluid microglial markers in Alzheimer's disease: elevated chitotriosidase activity but lack of diagnostic utility.
Cerebrospinal Fluid YKL-40 and Chitotriosidase Levels in Frontotemporal Dementia Vary by Clinical, Genetic and Pathological Subtype.
Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease.
Chitinase expression in Alzheimer's disease and non-demented brains regions.
Chitinase1 contributed to a potential protection via microglia polarization and A? oligomer reduction in D-galactose and aluminum-induced rat model with cognitive impairments.
Chitotriosidase and Alzheimer's disease.
Chitotriosidase and inflammatory mediator levels in Alzheimer's disease and cerebrovascular dementia.
Chitotriosidase attenuates brain inflammation via HDAC3/NF-?B pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
Extreme Stability of Chitotriosidase in Cerebrospinal Flulid makes it a Suitable Marker for Microglial Activation in Clinical Trials.
Frontal cortex chitinase and pentraxin neuroinflammatory alterations during the progression of Alzheimer's disease.
Functional Properties of Mouse Chitotriosidase Expressed in the Periplasmic Space of Escherichia coli.
Increased Levels of Chitotriosidase and YKL-40 in Cerebrospinal Fluid from Patients with Alzheimer's Disease.
Plasma level of chitinase 3-like 1 protein increases in patients with early Alzheimer's disease.
Amebiasis
Chitinase-gene-based analysis of the genetic variability among the clinical isolates of
Amyloidosis
A case of type I Gaucher disease with cardiopulmonary amyloidosis and chitotriosidase deficiency.
Amyotrophic Lateral Sclerosis
Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.
Chitotriosidase - a putative biomarker for sporadic amyotrophic lateral sclerosis.
Chitotriosidase and lysosomal enzymes as potential biomarkers of disease progression in amyotrophic lateral sclerosis: a survey clinic-based study.
Chitotriosidase as biomarker for early stage amyotrophic lateral sclerosis: a multicenter study.
Chitotriosidase, a biomarker of amyotrophic lateral sclerosis, accentuates neurodegeneration in spinal motor neurons through neuroinflammation.
Chitotriosidase: shucking the role of microglia in amyotrophic lateral sclerosis.
Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes.
CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia.
CSF chitinase proteins in amyotrophic lateral sclerosis.
CSF chitinases before and after symptom onset in amyotrophic lateral sclerosis.
Etiogenic factors present in the cerebrospinal fluid from amyotrophic lateral sclerosis patients induce predominantly pro-inflammatory responses in microglia.
Evaluation of Chitotriosidase and CC-Chemokine Ligand 18 as Biomarkers of Microglia Activation in Amyotrophic Lateral Sclerosis.
Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy.
Monocyte-Derived Macrophages Contribute to Chitinase Dysregulation in Amyotrophic Lateral Sclerosis: A Pilot Study.
Anaplasmosis
Anaplasmosis complement-fixation antigen production.
Anemia
Acute Gaucher Disease-Like Condition in an Indian Infant with a Novel Biallelic Mutation in the Prosaposin Gene.
Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children.
Generation of osteoclasts from type 1 Gaucher patients and correlation with clinical and genetic features of disease.
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
Anemia, Hypochromic
Putrescine (1,4-diaminobutane) as an indicator of pollution-induced stress in higher plants: barley and rape stressed with Cr(III) or Cr(VI).
Anemia, Sickle Cell
Plasma chitotriosidase and carotid intima-media thickness in children with sickle cell disease.
Angina, Unstable
Serum Chitotriosidase Activity in Acute Coronary Syndrome.
Appendicitis
Serum chitotriosidase activity in acute appendicitis: preliminary results.
Arteritis
Serum Chitotriosidase Activity in Acute Coronary Syndrome.
Arthritis
Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients.
Chitotriosidase activity in juvenile idiopathic arthritis.
Human secreted protein SI-CLP aggravates the inflammation of rheumatoid arthritis and is a potential macrophage inflammatory regulator.
[Some data concerning the incidence of infectious, nonspecific polyarthritis in 1 of the districs of Chita]
Arthritis, Juvenile
Chitinase 3-like-1 is produced by human Th17 cells and correlates with the level of inflammation in juvenile idiopathic arthritis patients.
Chitotriosidase activity in juvenile idiopathic arthritis.
Arthritis, Rheumatoid
Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization.
Human secreted protein SI-CLP aggravates the inflammation of rheumatoid arthritis and is a potential macrophage inflammatory regulator.
Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects.
Aspartylglucosaminuria
Plasma chitotriosidase in male Fabry patients: a marker for monitoring lipid-laden macrophages and their correction by enzyme replacement therapy.
Aspergillosis
Chitinase Induction Prior to Caspofungin Treatment of Experimental Invasive Aspergillosis in Neutropenic Rats Does Not Enhance Survival.
Immuno-polymerase chain reaction for detection ofAspergillus fumigatus.
Induction of chitinase in response to Aspergillus infection in sorghum (Sorghum bicolor (L) Moench).
Asthma
A chitinase-like protein in the lung and circulation of patients with severe asthma.
A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts.
A genetic variation in CHI3L1 is associated with bronchial asthma.
A possible role of chitin in the pathogenesis of asthma and allergy.
Acidic Chitinase-Chitin Complex Is Dissociated in a Competitive Manner by Acetic Acid: Purification of Natural Enzyme for Supplementation Purposes.
Acidic Mammalian chitinase and the eye: implications for ocular inflammatory diseases.
Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation.
Acidic mammalian chitinase in dry eye conditions.
Acidic Mammalian Chitinase Negatively Affects Immune Responses during Acute and Chronic Aspergillus fumigatus Exposure.
Acidic mammalian chitinase--a potential target for asthma therapy.
Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor.
Association between risk of asthma and gene polymorphisms in CHI3L1 and CHIA: a systematic meta-analysis.
Association of 24 bp Duplication of Human CHIT1 Gene with Asthma in a Heterozygous Population of North India: A Case-Control Study.
Association of IL13R alpha 1 +1398A/G polymorphism in a North Indian population with asthma: A case-control study.
Benzoxazepine-Derived Selective, Orally Bioavailable Inhibitor of Human Acidic Mammalian Chitinase.
CHI3L1 polymorphisms associate with asthma in a Taiwanese population.
CHI3L1 polymorphisms, cord blood YKL-40 levels and later asthma development.
CHIT1 mutations: genetic risk factor for severe asthma with fungal sensitization?
Chitinase 3-like 1 polymorphisms and risk of chronic obstructive pulmonary disease and asthma in a Chinese population.
Chitinase 3-like 1 protein plays a critical role in respiratory syncytial virus-induced airway inflammation.
Chitinase activates protease-activated receptor-2 in human airway epithelial cells.
Chitinase activation in patients with fungus-associated cystic fibrosis lung disease.
Chitinase levels in the tears of subjects with ocular allergies.
Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases - Current Concepts and Potential Applications.
Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies.
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Chitotriosidase inhibits allergic asthmatic airways via regulation of TGF-? expression and Foxp3
Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit.
Chitotriosidase: a marker and modulator of lung disease.
Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity.
Comparison of serum biomarkers between patients with asthma and with chronic obstructive pulmonary disease.
Dexamethasone alters bronchoalveolar lavage fluid proteome in a mouse asthma model.
Differences in the chitinolytic activity of mammalian chitinases on soluble and insoluble substrates.
Differential allergy responses to Metarhizium anisopliae fungal component extracts in BALB/c mice.
Differential enzymatic activity of common haplotypic versions of the human acidic mammalian chitinase protein.
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Duplication in CHIT1 gene and the risk for Aspergillus lung disease in CF patients.
Effect of Onchocerca volvulus chitinase on MUC5B expression in human airway epithelial cells.
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
Evolutionary and biochemical differences between human and monkey acidic mammalian chitinases.
Expression and role of acidic mammalian chitinase and eotaxin-3 in chronic rhinosinusitis with nasal polyps.
Fungal chitin from asthma-associated home environments induces eosinophilic lung infiltration.
Fungal exposure modulates the effect of polymorphisms of chitinases on emergency department visits and hospitalizations.
Genetic association of acidic mammalian chitinase with atopic asthma and serum total IgE levels.
Genetic polymorphisms of chitotriosidase in Caucasian children with bronchial asthma.
Genetic variation in chitinase 3-like 1 (CHI3L1) contributes to asthma severity and airway expression of YKL-40.
Graphene oxide attenuates Th2-type immune responses, but augments airway remodeling and hyperresponsiveness in a murine model of asthma.
Human acidic mammalian chitinase as a novel target for anti-asthma drug design using in silico screening.
Human chitinases and chitinase-like proteins as indicators for inflammation and cancer.
Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Identification and characterization of acidic mammalian chitinase inhibitors.
Improved fluorescent labeling of chitin oligomers: Chitinolytic properties of acidic mammalian chitinase under somatic tissue pH conditions.
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS.
Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis.
Increased expression of acidic mammalian chitinase in chronic rhinosinusitis with nasal polyps.
Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease.
Inhibition of Acidic Mammalian Chitinase by RNA Interference Suppresses OVA-sensitized Allergic Asthma.
Joint influences of Acidic-Mammalian-Chitinase with Interleukin-4 and Toll-like receptor-10 with Interleukin-13 in the genetics of asthma.
Kinetic characterization of recombinant human acidic Mammalian chitinase.
Loss and Gain of Human Acidic Mammalian Chitinase Activity by Nonsynonymous SNPs.
Marked differences in tissue-specific expression of chitinases in mouse and man.
Measurement of Chitinase Activity in Biological Samples.
Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1.
NOD
Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease.
Polymorphisms and haplotypes of acid mammalian chitinase are associated with bronchial asthma.
Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells.
Protein A-mouse acidic mammalian chitinase-V5-His expressed in periplasmic space of Escherichia coli possesses chitinase functions comparable to CHO-expressed protein.
Pulmonary cryptococcosis induces chitinase in the rat.
Role of Mammalian Chitinases in Asthma.
Role of mammalian chitinases in inflammatory conditions.
Role of YKL-40 in Bronchial Smooth Muscle Remodeling in Asthma.
Segmental allergen challenge enhances chitinase activity and levels of CCL18 in mild atopic asthma.
Serum chitotriosidase levels in patients with allergic and non-allergic asthma.
Significant Association of Chitinase 3-like 1 Genotypes to Asthma Risk in Taiwan.
Structure-based dissection of the natural product cyclopentapeptide chitinase inhibitor argifin.
Targeting Acidic Mammalian chitinase Is Effective in Animal Model of Asthma.
The biology of the Gaucher cell: the cradle of human chitinases.
The CHI3L1 rs4950928 polymorphism is associated with asthma-related hospital admissions in children and young adults.
The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.
The composition of house dust mite is critical for mucosal barrier dysfunction and allergic sensitisation.
The Correlation between Chitin and Acidic Mammalian Chitinase in Animal Models of Allergic Asthma.
The effects of an insertion in the 5'UTR of the AMCase on gene expression and pulmonary functions.
The Journal of Epithelial Biology and Pharmacology.
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.
YKL-40 in asthmatic patients, and its correlations with exacerbation, eosinophils and immunoglobulin E.
[Study on the discovery of novel chitinase inhibitors based on natural products].
Astrocytoma
The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.
Atherosclerosis
Chitinase inhibition promotes atherosclerosis in hyperlipidemic mice.
Chitotriosidase as a novel biomarker of early atherosclerosis in hemodialysis patients.
Chitotriosidase as a possible marker of clinically evidenced atherosclerosis in dyslipidemic children.
Chitotriosidase enzyme activity: is this a possible chronic inflammation marker in children with common variable immunodeficiency and early atherosclerosis?
Chitotriosidase genotype and serum activity in subjects with combined hyperlipidemia: effect of the lipid-lowering agents, atorvastatin and bezafibrate.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Expression of Chitotriosidase in Macrophages Modulates Atherosclerotic Plaque Formation in Hyperlipidemic Mice.
Increased Expression of Chitinase 3-Like 1 in Aorta of Patients with Atherosclerosis and Suppression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Chitinase 3-Like 1 Gene Silencing.
Increased Risk of Atherosclerosis in Patients with Sarcoidosis.
Plasma Chitotriosidase Activity and Arteriogenic Erectile Dysfunction: Association with the Presence, Severity, and Duration.
Plasma chitotriosidase and carotid intima-media thickness in children with sickle cell disease.
Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events.
Premature atherosclerosis in children with ?-thalassemia major.
Role of changes in serum chitotriosidase activity in mice under conditions of hyperlipidemia and lipid-lowering effect of carboxymethylated (1-3)-?-D-glycan.
Serum chitotriosidase activity is increased in subjects with atherosclerosis disease.
Serum cystatin C and chitotriosidase in acute P-407 induced dyslipidemia: Can they serve as potential early biomarkers for atherosclerosis?
Strong induction of members of the chitinase family of proteins in atherosclerosis: chitotriosidase and human cartilage gp-39 expressed in lesion macrophages.
The effect of nonsurgical periodontal treatment on serum and saliva chitotriosidase activities in patients with periodontitis and coronary artery disease.
The Journal of Epithelial Biology and Pharmacology.
[Chitotriosidase of human macrophages and mammalian chitinases: biological functions and abnormalities in pathology]
[Effect of statins on activity of matrix metalloproteases and serum concentration of cystatin C in patients with various risk of development of ischemic heart disease and in patients after coronary artery bypass surgery].
Autoimmune Diseases
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Bacterial Infections
Antivirulence properties of an antifreeze protein.
Characterization and expression analysis of chitinase genes (CHIT1, CHIT2 and CHIT3) in turbot (Scophthalmus maximus L.) following bacterial challenge.
CHI3L1 alleviate acute liver injury by inhibiting Th1 cells differentiation through STAT3 signaling pathway.
Chitinase 3-like-1 deficient donor splenocytes accentuated the pathogenesis of acute graft-versus-host diseases through regulating T cell expansion and type I inflammation.
Chitotriosidase in neonates with fungal and bacterial infections.
Genetic engineering strategies for biotic and abiotic stress tolerance and quality enhancement in horticultural crops: a comprehensive review.
Promoter activation of pepper class II basic chitinase gene, CAChi2, and enhanced bacterial disease resistance and osmotic stress tolerance in the CAChi2-overexpressing Arabidopsis.
The Listeria monocytogenes ChiA Chitinase Enhances Virulence through Suppression of Host Innate Immunity.
beta-Thalassemia
Elevated plasma chemokine CCL18/PARC in beta-thalassemia.
Plasma chitotriosidase activity in beta-thalassemia major: a comparative study between Sicilian and Sardinian patients.
Plasma chitotriosidase activity in patients with beta-thalassemia.
Plasma chitotriosidase activity is a marker of recovery in transplanted patients affected by beta-thalassemia major.
Serum YKL-40 levels and chitotriosidase activity in patients with beta-thalassemia major.
Blister
Association of a Novel Pinus monticola Chitinase Gene (PmCh4B) with Quantitative Resistance to Cronartium ribicola
Association of a novel Pinus monticola chitinase gene (PmCh4B) with quantitative resistance to Cronartium ribicola.
Certain factors associated with blister blight resistance in Camellia sinensis (L.) O. Kuntze.
Enhanced resistance to blister blight in transgenic tea (Camellia sinensis [L.] O. Kuntze) by overexpression of class I chitinase gene from potato (Solanum tuberosum).
Bone Resorption
Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells.
Determination of chitinases family during osteoclastogenesis.
Brain Injuries, Traumatic
Exacerbation of experimental autoimmune encephalomyelitis in the absence of breast regression protein 39/chitinase 3-like 1.
Role for mammalian chitinase 3-like protein 1 in traumatic brain injury.
Brain Ischemia
Chitotriosidase in patients with acute ischemic stroke.
Prognostic value of plasma chitotriosidase activity in acute stroke patients.
Brain Neoplasms
Transcriptional Effects of Dietary Exposure of Oil-Contaminated Calanus finmarchicus in Atlantic Herring (Clupea harengus).
Breast Neoplasms
Chitinase induces lysis of MCF-7 cells in culture and of human breast cancer xenograft B11-2 in SCID mice.
Chitotriosidase, a marker of innate immunity, is elevated in patients with primary breast cancer.
Fibroblasts drive an immunosuppressive and growth-promoting microenvironment in breast cancer via secretion of Chitinase 3-like 1.
Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer.
SI-CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor-associated macrophages.
Bronchial Hyperreactivity
Chitinase-Induced Airway Hyperreactivity and Inflammation in a Mouse Model of Nonallergic Asthma.
Polymorphisms and haplotypes of acid mammalian chitinase are associated with bronchial asthma.
Bronchiectasis
Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis.
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS.
Brucellosis
Evaluating the validity of serum neopterin and chitotriosidase levels in follow-up brucellosis patients.
[Epidemiology of brucellosis in the Chita region.]
Candidiasis
Chitotriosidase Activity Is Counterproductive in a Mouse Model of Systemic Candidiasis.
Serial chitotriosidase activity estimations in neonatal systemic candidiasis.
Candidiasis, Oral
Fluorescence staining vs. routine KOH smear for rapid diagnosis of oral candidiasis-A diagnostic test.
Candidiasis, Vulvovaginal
Chitooligosaccharides and Thermostable Chitinase Against Vulvovaginal Candidiasis and Saprophyte Fungi: LC Mass Studies of Shrimp Shell Fermentation by Bacillus altitudinis.
Carcinogenesis
Chitinase 3 like 1 suppresses the stability and activity of p53 to promote lung tumorigenesis.
Roles of chitinase 3-like 1 in the development of cancer, neurodegenerative diseases, and inflammatory diseases.
Carcinoma
Chitinase 3-like 1 secreted by peritumoral macrophages in esophageal squamous cell carcinoma is a favorable prognostic factor for survival.
High expression of Chitinase 3-like-1 is an unfavorable prognostic factor in urothelial carcinoma of upper urinary tract and urinary bladder.
Increased expression and possible role of chitinase 3-like-1 in a colitis-associated carcinoma model.
Increased expression of Chitinase 3-like 1 and microvessel density predicts metastasis and poor prognosis in clear cell renal cell carcinoma.
M2 Macrophage Marker Chitinase 3-Like 2 (CHI3L2) Associates With Progression of Conventional Renal Cell Carcinoma.
Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia.
Carcinoma, Hepatocellular
Chitinase 3-like-1, Tolloid-like protein 1, and intergenic gene polymorphisms are predictors for hepatocellular carcinoma development after hepatitis C virus eradication by direct-acting antivirals.
Correlation of Chitinase 3-Like 1 Single Nucleotide Polymorphisms with Hepatocellular Carcinoma in Taiwan.
The expression of chitinase 3-like 1: a novel prognostic predictor for hepatocellular carcinoma.
Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy.
Carcinoma, Non-Small-Cell Lung
Increased expression of chitinase 3-like 1 is a prognosis marker for non-small cell lung cancer correlated with tumor angiogenesis.
Carcinoma, Ovarian Epithelial
Preoperative serum YKL-40 is a marker for detection and prognosis of endometrial cancer.
Carcinoma, Renal Cell
Increased expression of Chitinase 3-like 1 and microvessel density predicts metastasis and poor prognosis in clear cell renal cell carcinoma.
M2 Macrophage Marker Chitinase 3-Like 2 (CHI3L2) Associates With Progression of Conventional Renal Cell Carcinoma.
Cardiovascular Diseases
[Primary disability in cardiovascular diseases in Chita during the years 1967-1971]
Carotid Stenosis
Serum chitotriosidase activity is increased in subjects with atherosclerosis disease.
Celiac Disease
Identification of Chitinase-3-like protein 1 as a novel neutrophil antigenic target in Crohn's disease.
Chickenpox
An uncommon cause of early infantile liver disease and raised chitotriosidase.
chitinase deficiency
A case of type I Gaucher disease with cardiopulmonary amyloidosis and chitotriosidase deficiency.
Acidic chitinase primes the protective immune response to gastrointestinal nematodes.
Acidic Mammalian Chitinase Negatively Affects Immune Responses during Acute and Chronic Aspergillus fumigatus Exposure.
CCL18 as an alternative marker in Gaucher and Niemann-Pick disease with chitotriosidase deficiency.
Chitinase activation in patients with fungus-associated cystic fibrosis lung disease.
Chitotriosidase deficiency in Brazil: evaluation of enzyme activity and genotypes.
Chitotriosidase deficiency in survivors of Candida sepsis.
Chitotriosidase deficiency in the Cypriot population: Identification of a novel deletion in the CHIT1 gene.
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population.
Chitotriosidase Deficiency: A Mutation Update in an African Population.
Clinical evaluation of chitotriosidase enzyme activity in Gaucher and Niemann Pick A/B diseases: A retrospective study from India.
High prevalence of chitotriosidase deficiency in Peruvian Amerindians exposed to chitin-bearing food and enteroparasites.
Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Plasma chitotriosidase activity in acute Plasmodium falciparum malaria.
Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae.
The human chitotriosidase gene. Nature of inherited enzyme deficiency.
[Application of plasma glucosylsphingosine detection in the follow-up of patients with Gaucher disease].
Cholera
Cholera, copepods, and chitinase.
Proteomic analysis of the vibrio cholerae type II secretome reveals new proteins including three related serine proteases.
The extracellular transport signal of the Vibrio cholerae endochitinase (ChiA) is a structural motif located between amino acids 75 and 555.
[Cholera vibrios lectins as main pathogenicity and persistence factors (biotechnological aspects of use)].
Cholestasis
Oxysterol/chitotriosidase based selective screening for Niemann-Pick type C in infantile cholestasis syndrome patients.
Cholesterol Ester Storage Disease
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
Chromoblastomycosis
Diagnostic value of fluorescein-labeled chitinase staining in formalin-fixed and paraffin-embedded tissues of fungal disease.
Chronic Limb-Threatening Ischemia
Evaluation of Chitotriosidase as a Marker of Inflammatory Status in Critical Limb Ischemia.
Chronic Periodontitis
The effect of nonsurgical periodontal treatment on serum and saliva chitotriosidase activities in patients with periodontitis and coronary artery disease.
Coccidioidomycosis
Disruption of the gene which encodes a serodiagnostic antigen and chitinase of the human fungal pathogen Coccidioides immitis.
Colitis
A Review of Selected IBD Biomarkers: From Animal Models to Bedside.
Chitinase 3-like 1 Synergistically Activates IL6-mediated STAT3 Phosphorylation in Intestinal Epithelial Cells in Murine Models of Infectious Colitis.
Oral caffeine administration ameliorates acute colitis by suppressing chitinase 3-like 1 expression in intestinal epithelial cells.
Role of mammalian chitinases in inflammatory conditions.
Colitis, Ulcerative
Identification of Chitinase-3-like protein 1 as a novel neutrophil antigenic target in Crohn's disease.
Colitis-Associated Neoplasms
Chitinase 3-like 1 induces survival and proliferation of intestinal epithelial cells during chronic inflammation and colitis-associated cancer by regulating S100A9.
Potential association between TLR4 and chitinase 3-like 1 (CHI3L1/YKL-40) signaling on colonic epithelial cells in inflammatory bowel disease and colitis-associated cancer.
Colorectal Neoplasms
Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer.
Chitinase 3-Like 1, Nestin, and Testin Proteins as Novel Biomarkers of Potential Clinical Use in Colorectal Cancer: A Review.
Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis.
Plasma chitinase 3-like 1 is persistently elevated during first month after minimally invasive colorectal cancer resection.
Polymorphisms in the CHIT1 gene: Associations with colorectal cancer.
Serum chitinase activity prognosticates metastasis of colorectal cancer.
Common Variable Immunodeficiency
Chitotriosidase enzyme activity: is this a possible chronic inflammation marker in children with common variable immunodeficiency and early atherosclerosis?
Communicable Diseases
Chitotriosidase in patients with acute ischemic stroke.
Elevated plasma chitotriosidase activity in various lysosomal storage disorders.
Identification of Salivary Microbiota and Its Association With Host Inflammatory Mediators in Periodontitis.
The chitinases expression is related to Simian Immunodeficiency Virus Encephalitis (SIVE) and in HIV encephalitis (HIVE).
The Journal of Epithelial Biology and Pharmacology.
Confusion
Plasma methylumbelliferyl-tetra-N-acetyl-chitotetraoside hydrolase: further study of its characteristics as a chitinase and comparison with its activity on Remazol Brilliant Violet carboxymethyl chitin.
Conjunctivitis, Allergic
Acidic Mammalian chitinase and the eye: implications for ocular inflammatory diseases.
Effect of chitinase inhibitors on endotoxin-induced uveitis (EIU) in rabbits.
Coronary Artery Disease
24 bp duplication of CHIT1 gene is not correlated with coronary artery disease in Corsica Island (France).
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Genetic polymorphisms in chitinase 3-like 1 (CHI3L1) are associated with circulating YKL-40 levels, but not with angiographic coronary artery disease in a Chinese population.
Increased Expression of Chitinase 3-Like 1 in Aorta of Patients with Atherosclerosis and Suppression of Atherosclerosis in Apolipoprotein E-Knockout Mice by Chitinase 3-Like 1 Gene Silencing.
Serum chitotriosidase activity in patients with coronary artery disease.
The effect of nonsurgical periodontal treatment on serum and saliva chitotriosidase activities in patients with periodontitis and coronary artery disease.
Coronary Disease
Chitinase 3-like 1 gene-329G/A polymorphism, plasma concentration and risk of coronary heart disease in a Chinese population.
Serum Chitotriosidase Activity, a Marker of Activated Macrophages, Predicts New Cardiovascular Events Independently of C-Reactive Protein.
COVID-19
Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19.
Proteomic characteristics of bronchoalveolar lavage fluid in critical COVID-19 patients.
Creutzfeldt-Jakob Syndrome
CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia.
Crohn Disease
Identification of Chitinase-3-like protein 1 as a novel neutrophil antigenic target in Crohn's disease.
Cryptococcosis
Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection.
Chitotriosidase and gene therapy for fungal infections.
Pulmonary cryptococcosis induces chitinase in the rat.
Cystic Fibrosis
Chitinase activation in patients with fungus-associated cystic fibrosis lung disease.
Functional Properties of Mouse Chitotriosidase Expressed in the Periplasmic Space of Escherichia coli.
Cystinosis
Chitotriosidase as a Novel Biomarker for Therapeutic Monitoring of Nephropathic Cystinosis.
Chitotriosidase plasma activity in nephropathic cystinosis.
Clinical utility of chitotriosidase enzyme activity in nephropathic cystinosis.
Cysts
Biology of Giardia lamblia. Detection of N-acetyl-D-glucosamine as the only surface saccharide moiety and identification of two distinct subsets of trophozoites by lectin binding.
Chitinase activity in encysting Entamoeba invadens and its inhibition by allosamidin.
Chitinase dependent control of protozoan cyst burden in the brain.
Different structure and mRNA expression of Entamoeba invadens chitinases in the encystation and excystation.
Entamoeba Chitinase is Required for Mature Round Cyst Formation.
Evidence for a "wattle and daub" model of the cyst wall of entamoeba.
Giardia cyst wall-specific carbohydrate: evidence for the presence of galactosamine.
Identification and partial characterization of three chitinase forms in Entamoeba invadens with emphasis on their inhibition by allosamidin.
Identification of chitin as a structural component of Giardia cysts.
Responses of Entamoeba invadens to heat shock and encystation are related.
The cyst wall of Entamoeba invadens contains chitosan (deacetylated chitin).
The Jacob2 lectin of the Entamoeba histolytica cyst wall binds chitin and is polymorphic.
The most abundant glycoprotein of amebic cyst walls (Jacob) is a lectin with five Cys-rich, chitin-binding domains.
The parasitic and lethal effects of Trichoderma longibrachiatum against Heterodera avenae
Transcriptional profiling of Entamoeba histolytica trophozoites.
Unique posttranslational modifications of chitin-binding lectins of Entamoeba invadens cyst walls.
[Parasitic and lethal action of Trichoderma longibrachiatum against Heterodera avenae].
Dehydration
Antifreeze protein complements cryoprotective dehydration in the freeze-avoiding springtail Megaphorura arctica.
Cloning of a cDNA for a chitinase homologue which lacks chitin-binding sites and is down-regulated by water stress and wounding.
Induced expression of the class II chitinase gene during cold acclimation and dehydration of bermudagrass (Cynodon sp.). [Erratum: Dec 2001, v. 103 (8), p. 1312].
Isolation of an osmotic stress- and abscisic acid-induced gene encoding an acidic endochitinase from Lycopersicon chilense.
[Intercellular 27 kD protein is a chitinase induced by water stress or Pseudoperonospora cubensis in cucumber leaves]
Dementia
Chitotriosidase and inflammatory mediator levels in Alzheimer's disease and cerebrovascular dementia.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Serum markers of monocyte/macrophage activation in patients with Alzheimer's disease and other types of dementia.
Demyelinating Diseases
Increased cerebrospinal fluid chitinase 3-like 1 and neurofilament light chain in pediatric acquired demyelinating syndromes.
Dermatitis
Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice.
Dermatitis, Contact
Expression of chitinase-like proteins in the skin of chronic proliferative dermatitis (cpdm/cpdm) mice.
Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Dermatomycoses
Utilization of chitinase in treatment of dermatomycosis. I. Influence of Bacilli chitinovori on the culture of dermatophytes.
Utilization of chitinase in treatment of dermatomycosis. II. Influence of crude chitinase fluid on the culture of fungi.
Diabetes Complications
Chitinase 3 Like-1: An Emerging Molecule Involved in Diabetes and Diabetic Complications.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Diabetes Mellitus
Chitotriosidase activity predicts endothelial dysfunction in type-2 diabetes mellitus.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Evaluation of Chitotriosidase and Neopterin as Biomarkers of Microvascular Complications in Patients with Type 1 Diabetes Mellitus.
Serum chitotriosidase enzyme activity is closely related to HbA1c levels and the complications in patients with diabetes mellitus type 2.
Diabetes Mellitus, Type 1
Chitinase expression in parotid glands of non-obese diabetic mice.
Evaluation of Chitotriosidase and Neopterin as Biomarkers of Microvascular Complications in Patients with Type 1 Diabetes Mellitus.
Diabetes Mellitus, Type 2
Association of chitotriosidase enzyme activity and genotype with the risk of nephropathy in type 2 diabetes.
Changes in glycosylation of human blood plasma chitotriosidase in patients with type 2 diabetes.
Increased chitotriosidase activity in plasma of patients with type 2 diabetes.
Neutrophils as a Source of Chitinases and Chitinase-Like Proteins in Type 2 Diabetes.
Diabetic Angiopathies
Increased chitotriosidase activity in plasma of patients with type 2 diabetes.
Diabetic Nephropathies
Association of chitotriosidase enzyme activity and genotype with the risk of nephropathy in type 2 diabetes.
Diabetic Neuropathies
Evaluation of Chitotriosidase and Neopterin as Biomarkers of Microvascular Complications in Patients with Type 1 Diabetes Mellitus.
Diabetic Retinopathy
C-reactive protein and chitinase 3-like protein 1 as biomarkers of spatial redistribution of retinal blood vessels on digital retinal photography in patients with diabetic retinopathy.
The changing features of serum adropin, copeptin, neprilysin and chitotriosidase which are associated with vascular endothelial function in type 2 diabetic retinopathy patients.
Diphtheria
[Studies on epidemiology and prevention of diphtheria in Chita.]
Disorders of Excessive Somnolence
Cerebrospinal fluid biomarkers of neurodegeneration are decreased or normal in narcolepsy.
Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy.
Drug Hypersensitivity
Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Dry Eye Syndromes
Acidic Mammalian chitinase and the eye: implications for ocular inflammatory diseases.
Acidic mammalian chitinase in dry eye conditions.
Dyslipidemias
Serum cystatin C and chitotriosidase in acute P-407 induced dyslipidemia: Can they serve as potential early biomarkers for atherosclerosis?
Elephantiasis
Differential recognition of microfilarial chitinase, a transmission-blocking vaccine candidate antigen, by sera from patients with Brugian and Bancroftian filariasis.
Elephantiasis, Filarial
Differential recognition of microfilarial chitinase, a transmission-blocking vaccine candidate antigen, by sera from patients with Brugian and Bancroftian filariasis.
Evaluation of recombinant chitinase antigen in serological diagnosis and surveillance of lymphatic filariasis.
The Genetic Polymorphisms of 24 Base Pair Duplication and Point G102S of Human Chitotriosidase to Bancroftian Filariasis at the Thai?Myanmar Border.
Transmission-blocking antibodies recognize microfilarial chitinase in brugian lymphatic filariasis.
Encephalitis
Chitotriosidase attenuates brain inflammation via HDAC3/NF-?B pathway in D-galactose and aluminum-induced rat model with cognitive impairments.
The chitinases expression is related to Simian Immunodeficiency Virus Encephalitis (SIVE) and in HIV encephalitis (HIVE).
Encephalomyelitis
An attempt to produce a complement-fixation antigen for the avian encephalomyelitis virus from infected chick embryo brains.
Endometrial Neoplasms
YKL-40 Protein Levels and Clinical Outcome of Human Endometrial Cancer.
Endometriosis
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Chitotriosidase levels in patients with severe endometriosis.
Eosinophilia
Analyzing airway inflammation with chemical biology: dissection of acidic mammalian chitinase function with a selective drug-like inhibitor.
Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-?B.
Fungal chitin from asthma-associated home environments induces eosinophilic lung infiltration.
The Correlation between Chitin and Acidic Mammalian Chitinase in Animal Models of Allergic Asthma.
Eosinophilic Esophagitis
Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis.
Erectile Dysfunction
Plasma Chitotriosidase Activity and Arteriogenic Erectile Dysfunction: Association with the Presence, Severity, and Duration.
Escherichia coli Infections
Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection.
Esophageal Squamous Cell Carcinoma
Chitinase 3-like 1 secreted by peritumoral macrophages in esophageal squamous cell carcinoma is a favorable prognostic factor for survival.
Eye Diseases
Chitinase levels in the tears of subjects with ocular allergies.
High-level expression of a tobacco chitinase gene in Nicotiana sylvestris. Susceptibility of transgenic plants to Cercospora nicotianae infection.
Fabry Disease
Plasma chitotriosidase in male Fabry patients: a marker for monitoring lipid-laden macrophages and their correction by enzyme replacement therapy.
Familial Mediterranean Fever
Decreased Chitotriosidase Activity and Levels in Familial Mediterranean Fever.
S1000A12, Chitotriosidase, and Resolvin D1 as Potential Biomarkers of Familial Mediterranean Fever.
Fatty Liver
Adiponectin and the steatosis marker Chi3L1 decrease following switch to raltegravir compared to continued PI/NNRTI-based antiretroviral therapy.
Association of chitotriosidase genotype with the development of non-alcoholic fatty liver disease.
Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease.
Potential role of chitotriosidase gene in nonalcoholic Fatty liver disease evolution.
Filariasis
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population.
Evaluation of recombinant chitinase and SXP1 antigens as antimicrofilarial vaccines.
Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis.
[Evaluation of DNA recombinant chitinase fusion protein antigens in serological diagnosis for filariasis]
Food Hypersensitivity
Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization.
Maize food allergy: lipid-transfer proteins, endochitinases, and alpha-zein precursor are relevant maize allergens in double-blind placebo-controlled maize-challenge-positive patients.
Foot Rot
Differential induction of chitinase in Piper colubrinum in response to inoculation with Phytophthora capsici, the cause of foot rot in black pepper.
Frontotemporal Dementia
Cerebrospinal Fluid YKL-40 and Chitotriosidase Levels in Frontotemporal Dementia Vary by Clinical, Genetic and Pathological Subtype.
Frontotemporal Lobar Degeneration
Cerebrospinal Fluid YKL-40 and Chitotriosidase Levels in Frontotemporal Dementia Vary by Clinical, Genetic and Pathological Subtype.
Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.
CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia.
Fucosidosis
The expanding spectrum of disorders with elevated plasma chitotriosidase activity: an update.
Fusariosis
Immunolocalization of a class III chitinase in two muskmelon cultivars reacting differently to Fusarium oxysporum f. sp. melonis.
Gangliosidoses
Dual Diagnosis of Dihydropyrimidine Dehydrogenase Deficiency and GM(1) Gangliosidosis.
Gangliosidosis, GM1
The Clinical and Molecular Spectrum of GM1 Gangliosidosis.
Gastritis
CHIT1 and AMCase expression in human gastric mucosa: correlation with inflammation and Helicobacter pylori infection.
Gastroenteritis
A Listeria monocytogenes ST2 clone lacking chitinase ChiB from an outbreak of non-invasive gastroenteritis.
Gaucher Disease
A case of type I Gaucher disease with cardiopulmonary amyloidosis and chitotriosidase deficiency.
A Rare Cause of Elevated Chitotriosidase Activity: Glycogen Storage Disease Type IV.
A rare form of Gaucher disease resulting from saposin C deficiency.
Aberrant progranulin, YKL-40, cathepsin D and cathepsin S in Gaucher disease.
Accuracy of chitotriosidase activity and CCL18 concentration in assessing type I Gaucher disease severity. A systematic review with meta-analysis of individual participant data.
Acute Gaucher Disease-Like Condition in an Indian Infant with a Novel Biallelic Mutation in the Prosaposin Gene.
Allele frequency of a 24?bp duplication in exon 10 of the CHIT1 gene in the general Korean population and in Korean patients with Gaucher disease.
Allelic frequency determination of the 24-bp chitotriosidase duplication in the Portuguese population by real-time PCR.
Biochemical and molecular characterization of adult patients with type I Gaucher disease and carrier frequency analysis of Leu444Pro - a common Gaucher disease mutation in India.
Biochemical and Molecular Chitotriosidase Profiles in Patients with Gaucher Disease Type 1 in Minas Gerais, Brazil: New Mutation in CHIT1 Gene.
Biochemical characterization of chitotriosidase enzyme: comparison between normal individuals and patients with Gaucher and with Niemann-Pick diseases.
Biochemical study on beta-glucosidase in individuals with Gaucher's disease and normal subjects.
Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease.
Biomarkers in Serbian patients with Gaucher disease.
Changes in serum chitotriosidase activity with cessation of replacement enzyme (cerebrosidase) administration in Gaucher disease.
Chitotriosidase Activity and Gene Polymorphism in Iranian Patients with Gaucher Disease and Sibling Carriers.
Chitotriosidase activity as additional biomarker in the diagnosis of lysosomal storage diseases.
Chitotriosidase as a marker of macrophage stimulation.
Chitotriosidase deficiency in survivors of Candida sepsis.
Chitotriosidase Deficiency: A Mutation Update in an African Population.
Chitotriosidase determination in plasma and in dried blood spots: a comparison using two different substrates in a microplate assay.
Chitotriosidase genotype and plasma activity in patients type 1 Gaucher's disease and their relatives (carriers and non carriers).
Chitotriosidase on treatment-naïve patients with Gaucher disease: A genotype vs phenotype study.
Chitotriosidase plasma activity in nephropathic cystinosis.
Chitotriosidase variants in patients with Gaucher disease. Implications for diagnosis and therapeutic monitoring.
Clinical evaluation of chitotriosidase enzyme activity in Gaucher and Niemann Pick A/B diseases: A retrospective study from India.
Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages.
Common G102S polymorphism in chitotriosidase differentially affects activity towards 4-methylumbelliferyl substrates.
Comparative functional analysis between human and mouse chitotriosidase: Substitution at amino acid 218 modulates the chitinolytic and transglycosylation activity.
Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for Gaucher disease.
Correlation of surrogate markers of Gaucher disease. Implications for long-term follow up of enzyme replacement therapy.
Could GSD type I expand the spectrum of disorders with elevated plasma chitotriosidase activity?
Critical assessment of chitotriosidase analysis in the rational laboratory diagnosis of children with Gaucher disease and Niemann-Pick disease type A/B and C.
Design and synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates.
Elevated plasma chemokine CCL18/PARC in beta-thalassemia.
Elevated plasma chitotriosidase activity in various lysosomal storage disorders.
Functional Properties of Mouse Chitotriosidase Expressed in the Periplasmic Space of Escherichia coli.
Gaucher disease and miscellaneous.
Gaucher disease: single gene molecular characterization of one-hundred Indian patients reveals novel variants and the most prevalent mutation.
High levels of human chitotriosidase hinder the formation of peritrophic membrane in anopheline vectors.
Human chitinases and chitinase-like proteins as indicators for inflammation and cancer.
Human chitotriosidase CHIT1 cross reacts with mammalian-like substrates.
Human chitotriosidase: a potential new marker of sarcoidosis severity.
Identification and use of biomarkers in Gaucher disease and other lysosomal storage diseases.
Identification of chitotriosidase isoforms in plasma of Gaucher disease patients by two dimensional gel electrophoresis.
Improvement In Symptoms Of Gaucher's Disease By Enzyme Replacement Therapy.
Incremental biomarker and clinical outcomes after switch from enzyme therapy to eliglustat substrate reduction therapy in Gaucher disease.
Marked differences in tissue-specific expression of chitinases in mouse and man.
Marked elevation of plasma chitotriosidase activity. A novel hallmark of Gaucher disease.
Marked elevation of the chemokine CCL18/PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention.
Measurement of Chitinase Activity in Biological Samples.
Misdiagnosis of Niemann-Pick disease type C as Gaucher disease.
Modelling long-term evolution of chitotriosidase in non-neuronopathic Gaucher disease.
Monitoring of Gaucher patients with a novel chitotriosidase assay.
New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis.
Plasma chitotriosidase activity in beta-thalassemia major: a comparative study between Sicilian and Sardinian patients.
Plasma chitotriosidase activity in Gaucher disease patients who have been treated either by bone marrow transplantation or by enzyme replacement therapy with alglucerase.
Plasma chitotriosidase activity in patients with beta-thalassemia.
Plasma chitotriosidase activity versus CCL18 level for assessing type I Gaucher disease severity: protocol for a systematic review with meta-analysis of individual participant data.
Plasma chitotriosidase activity versus plasma glucosylsphingosine in wide spectrum of Gaucher disease phenotypes - A statistical insight.
Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease.
Plasma chitotriosidase in male Fabry patients: a marker for monitoring lipid-laden macrophages and their correction by enzyme replacement therapy.
Plasmalogen levels in Gaucher disease.
Purification and characterization of human chitotriosidase, a novel member of the chitinase family of proteins.
Rapid screening for lipid storage disorders using biochemical markers. Expert center data and review of the literature.
Reduction in imiglucerase dosage causes immediate rise of chitotriosidase activity in patients with Gaucher disease.
Serum chitotriosidase enzyme activity is closely related to HbA1c levels and the complications in patients with diabetes mellitus type 2.
Serum Chitotriosidase, a Putative Marker of Chronically Activated Macrophages, Increases With Normal Aging.
Splenomegaly, cardiomegaly, and osteoporosis in a child with Gaucher disease.
Strong induction of members of the chitinase family of proteins in atherosclerosis: chitotriosidase and human cartilage gp-39 expressed in lesion macrophages.
Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins.
Superior effects of high-dose enzyme replacement therapy in type 1 Gaucher disease on bone marrow involvement and chitotriosidase levels: a 2-center retrospective analysis.
Sustained therapeutic effects of oral miglustat (Zavesca, N-butyldeoxynojirimycin, OGT 918) in type I Gaucher disease.
The Journal of Epithelial Biology and Pharmacology.
TNF-alpha levels and TNF-alpha gene polymorphism in type I Gaucher disease.
Transglycosidase activity of chitotriosidase: improved enzymatic assay for the human macrophage chitinase.
Twenty- five years of biochemical diagnosis of Gaucher disease: the Egyptian experience.
Type 1 Gaucher disease: null and hypomorphic novel chitotriosidase mutations-implications for diagnosis and therapeutic monitoring.
Type I Gaucher disease with severe skeletal destruction, extraosseous extension, and monoclonal gammopathy.
Validating glycoprotein non-metastatic melanoma B (gpNMB, osteoactivin), a new biomarker of Gaucher disease.
Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy.
[24-bp duplication on CHIT1 gene in Mexican population].
[Application of plasma glucosylsphingosine detection in the follow-up of patients with Gaucher disease].
[Biochemical and genetic diagnosis of Gaucher disease and its phenotypical heterogeneity]
[Chitotriosidase of human macrophages and mammalian chitinases: biological functions and abnormalities in pathology]
[Comparison and clinical application of two methods for determination of plasma chitotriosidase activity].
[Effect of enzyme replacement therapy on lipid profile in patients with Gaucher's disease]
[Gaucher disease and chitotriosidase]
[Plasma chitotriosidase activity in Argentinian patients with Gaucher disease, various lysosomal diseases and other inherited metabolic disorders]
[The possibility of increasing the precision of biochemical diagnostics of Gaucher disease]
Genetic Diseases, Inborn
Measurement of Chitinase Activity in Biological Samples.
Gingivitis
Chitinase in whole and glandular human salivas and in whole saliva of patients with periodontal inflammation.
Salivary Total Protease Activity Based on a Broad-Spectrum Fluorescence Resonance Energy Transfer Approach to Monitor Induction and Resolution of Gingival Inflammation.
Glioblastoma
Association between YKL-40 and adult primary astrocytoma.
Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma.
Chitinase 3-like 2 protein monoclonal antibodies.
Chitinase 3-like protein 2 (CHI3L2, YKL-39) activates phosphorylation of extracellular signal-regulated kinases ERK1/ERK2 in human embryonic kidney (HEK293) and human glioblastoma (U87 MG) cells.
Glucose Intolerance
Inflammatory marker levels in obese adolescents with glucose intolerance: Increased chitotriosidase activity.
glucosylceramidase deficiency
A case of type I Gaucher disease with cardiopulmonary amyloidosis and chitotriosidase deficiency.
Glycogen Storage Disease
A Rare Cause of Elevated Chitotriosidase Activity: Glycogen Storage Disease Type IV.
Could GSD type I expand the spectrum of disorders with elevated plasma chitotriosidase activity?
The expanding spectrum of disorders with elevated plasma chitotriosidase activity: an update.
Glycogen Storage Disease Type I
Could GSD type I expand the spectrum of disorders with elevated plasma chitotriosidase activity?
Glycogen Storage Disease Type IV
A Rare Cause of Elevated Chitotriosidase Activity: Glycogen Storage Disease Type IV.
Distinctly Elevated Chitotriosidase Activity in a Child with Congenital Andersen Disease (Glycogen Storage Disease Type IV).
The expanding spectrum of disorders with elevated plasma chitotriosidase activity: an update.
Graft vs Host Disease
Chitinase 3-like-1 deficient donor splenocytes accentuated the pathogenesis of acute graft-versus-host diseases through regulating T cell expansion and type I inflammation.
Chitinase 3-Like-1-Deficient Splenocytes Deteriorated the Pathogenesis of Acute Graft-Versus-Host Disease via Regulating Differentiation of Tfh Cells.
Granulomatosis with Polyangiitis
Serum chitotriosidase activity and Wegener's granulomatosis.
Heart Failure
Clinical significance of chitotriosidase in outpatients with advanced heart failure.
Hemorrhagic Fever, Crimean
Serum chitotriosidase enzyme activity in patients with Crimean-Congo hemorrhagic fever.
Hemorrhoids
[Detection and analysis of the characteristic expression of microRNAs of anal fistula patients].
Hepatitis
Chitinase 3-like-1 Promotes Intrahepatic Activation of Coagulation Through Induction of Tissue Factor in Mice.
Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells.
The clinical significance of serum chitinase 3-like 1 in hepatitis B-related chronic liver diseases.
Hepatitis B
Evaluation of Chitinase 3-like 1 (CHI3L1) as a noninvasive biomarker of hepatic fibrosis in patients with Hepatitis B virus-related compensated chronic liver disease.
The clinical significance of serum chitinase 3-like 1 in hepatitis B-related chronic liver diseases.
Hepatitis B, Chronic
Changes of serum Chitinase 3-like 1 levels correlate with changes of liver fibrosis measured by the two established quantitative methods in chronic hepatitis B patients following antiviral therapy.
Hepatitis C
Chitinase 3-like-1, Tolloid-like protein 1, and intergenic gene polymorphisms are predictors for hepatocellular carcinoma development after hepatitis C virus eradication by direct-acting antivirals.
Hepatomegaly
Elevated plasma chitotriosidase activity in various lysosomal storage disorders.
Glucosylsphingosine is a key biomarker of Gaucher disease.
Outcome of enzyme replacement therapy in patients with Gaucher disease type I. The Romanian experience.
Prominent increase in plasma ganglioside GM3 is associated with clinical manifestations of type I Gaucher disease.
Herpes Zoster
An uncommon cause of early infantile liver disease and raised chitotriosidase.
Optical coherence tomography-based assessment of retinal vascular pathology in cerebral small vessel disease.
Hookworm Infections
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population.
Hydrocephalus
Cerebrospinal fluid and serum chitotriosidase levels in patients with aneurysmal subarachnoid haemorrhage: preliminary results.
Increased plasma levels of chitinase 3-like 1 (CHI3L1) protein in patients with idiopathic normal-pressure hydrocephalus.
Hydrops Fetalis
The expanding spectrum of disorders with elevated plasma chitotriosidase activity: an update.
Hyperlipidemias
Chitotriosidase genotype and serum activity in subjects with combined hyperlipidemia: effect of the lipid-lowering agents, atorvastatin and bezafibrate.
Effect of atorvastatin on activities of matrix metalloproteinases and chitotriosidase in male and female mice with experimental hyperlipidemia.
Hypolipidemic Effect of Mannan in Mice with Acute Lipemia Induced by Poloxamer 407.
Role of changes in serum chitotriosidase activity in mice under conditions of hyperlipidemia and lipid-lowering effect of carboxymethylated (1-3)-?-D-glycan.
Selective effect of conjugated linoleic acid isomers on atherosclerotic lesion development in apolipoprotein E knockout mice.
[The role of changes in matrix metalloproteases and chitotriosidase in the mechanism of protective effect of atorvastatin in experimental murine lipemia]
Hypersensitivity
A possible role of chitin in the pathogenesis of asthma and allergy.
Association of 24 bp Duplication of Human CHIT1 Gene with Asthma in a Heterozygous Population of North India: A Case-Control Study.
Chitinase levels in the tears of subjects with ocular allergies.
Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies.
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Chitins and chitosans as immunoadjuvants and non-allergenic drug carriers.
Class I chitinases as potential panallergens involved in the latex-fruit syndrome.
Class I endochitinase containing a hevein domain is the causative allergen in latex-associated avocado allergy.
Expression and role of acidic mammalian chitinase and eotaxin-3 in chronic rhinosinusitis with nasal polyps.
Hevein-like protein domains as a possible cause for allergen cross-reactivity between latex and banana.
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS.
Inflammation during Schistosoma haematobium infection and anti-allergy in pre-school-aged children living in a rural endemic area in Zimbabwe.
Maize food allergy: lipid-transfer proteins, endochitinases, and alpha-zein precursor are relevant maize allergens in double-blind placebo-controlled maize-challenge-positive patients.
Safety evaluation of the food enzyme chitinase from Streptomyces violaceoruber (strain pChi).
Severe immediate allergic reactions to grapes: part of a lipid transfer protein-associated clinical syndrome.
Spectrum of allergens for Japanese cedar pollinosis and impact of component-resolved diagnosis on allergen-specific immunotherapy.
[Expression of AMCase mRNA in nasal mucosa of allergic rhinitis in SD rats].
Hypersplenism
[Enzyme therapy in children with severe forms of Gaucher's disease]
Hypertension
Association of chitotriosidase enzyme activity and genotype with the risk of nephropathy in type 2 diabetes.
Hypertension, Pulmonary
Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy.
Hypothyroidism
Increased serum chitotriosidase activity following restoration of euthyroidism in patients with subclinical hypothyroidism.
[Fatty acid composition of the blood serum and erythrocyte membrane lipids in patients with hypothyroidism and left ventricular diastolic dysfunction]
Idiopathic Hypersomnia
Cerebrospinal fluid biomarkers of neurodegeneration are decreased or normal in narcolepsy.
Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy.
Idiopathic Pulmonary Fibrosis
Chitinase 1 regulates pulmonary fibrosis by modulating TGF-?/SMAD7 pathway via TGFBRAP1 and FOXO3.
Chitotriosidase activity in patients with interstitial lung diseases.
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Two sides of a coin: the dual roles of chitinase 3-like 1 in idiopathic pulmonary fibrosis.
Immune System Diseases
Serum YKL-40 and IL 17 in Psoriasis: Reliability as prognostic markers for disease severity and responsiveness to treatment.
Infections
A Class IV Chitinase Is Up-Regulated by Fungal Infection and Abiotic Stresses and Associated with Slow-Canker-Growth Resistance to Cronartium ribicola in Western White Pine (Pinus monticola).
A class IV chitinase is up-regulated by fungal infection and abiotic stresses and associated with slow-canker-growth resistance to Cronartium ribicola in western white pine (Pinus monticola).
A Listeria monocytogenes ST2 clone lacking chitinase ChiB from an outbreak of non-invasive gastroenteritis.
A noncoding plant pathogen provokes both transcriptional and posttranscriptional alterations in tomato.
A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut.
A plant chitinase controls cortical infection thread progression and nitrogen-fixing symbiosis.
Accumulation of defense related transcripts in sunflower hypocotyls (Helianthus annuus L.) infected with Plasmopara halstedii.
Acidic and basic class III chitinase mRNA accumulation in response to TMV infection of tobacco.
Acidic mammalian chitinase tuning after enteric helminths eradication in inflammatory respiratory disease patients.
Activation of autophagic programmed cell death and innate immune gene expression reveals immuno-competence of integumental epithelium in Bombyx mori infected by a dipteran parasitoid.
Activity, stability and folding analysis of the chitinase from Entamoeba histolytica.
An acidic class III chitinase in sugar beet: induction by Cercospora beticola, characterization, and expression in transgenic tobacco plants.
An agglutinating chitinase with two chitin-binding domains confers fungal protection in transgenic potato.
An uncommon cause of early infantile liver disease and raised chitotriosidase.
Analysis of a chitinase from EpapGV, a fast killing betabaculovirus.
Analysis of variation in virulence of Beauveria bassiana against insect pests of pigeonpea using qPCR.
Aspergillus fumigatus corneal infection is regulated by chitin synthases and by neutrophil-derived acidic mammalian chitinase.
Assay for Assessing Mucin Binding to Bacteria and Bacterial Proteins.
Assessment of relations between clinical outcome of ischemic stroke and activity of inflammatory processes in the acute phase based on examination of selected parameters.
Association of the hydrolytic enzyme chitinase against Rhizoctonia solani in rhizobacteria-treated rice plants.
Biological control of the root-knot nematode Meloidogyne javanica by Trichoderma harzianum
BjMYB1, a transcription factor implicated in plant defence through activating BjCHI1 chitinase expression by binding to a W-box-like element.
Changes in gene expression profiles as they relate to the adult plant leaf rust resistance in the wheat cv. Toropi.
Characterisation and antifungal activity of extracellular chitinase from a biocontrol fungus, Trichoderma asperellum PQ34.
Characterization and expression analysis of a chitinase gene (PmChi-4) from black tiger shrimp (Penaeus monodon) under pathogen infection and ambient ammonia nitrogen stress.
Characterization and expression analysis of a chitinase gene (PmChi-5) from black tiger shrimp (Penaeus monodon) under pathogens infection and ambient ammonia-N stress.
Characterization and Ultrastructural Localization of Chitinases from Metarhizium anisopliae, M. flavoviride, and Beauveria bassiana during Fungal Invasion of Host (Manduca sexta) Cuticle.
Characterization of root-associated bacteria from paddy and its growth-promotion efficacy.
Characterization of the Maize Chitinase Genes and Their Effect on Aspergillus flavus and Aflatoxin Accumulation Resistance.
Chikungunya virus titration, detection and diagnosis using N-Acetylglucosamine (GlcNAc) specific lectin based virus capture assay.
CHIT1 and AMCase expression in human gastric mucosa: correlation with inflammation and Helicobacter pylori infection.
Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection.
Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1? and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia.
Chitinase 3-like 1 protein levels are elevated in Schistosoma haematobium infected children.
Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells.
Chitinase cDNA Cloning and mRNA Induction by Fungal Elicitor, Wounding, and Infection.
Chitinase Gene Positively Regulates Hypersensitive and Defense Responses of Pepper to Colletotrichum acutatum Infection.
Chitinase in roots of mycorrhizal Allium porrum: regulation and localization.
Chitinase levels in guinea pig blood are increased after systemic infection with Aspergillus fumigatus.
Chitinases and chitinase-like proteins: potential therapeutic targets for the treatment of T-helper type 2 allergies.
Chitinases of human parasites and their implications as antiparasitic targets.
Chitins and chitosans as immunoadjuvants and non-allergenic drug carriers.
Chitotriosidase and gene therapy for fungal infections.
Chitotriosidase: a marker and modulator of lung disease.
Cloning and characterization of a pathogen-induced chitinase in Brassica napus.
Cloning of the gene Lecanicillium psalliotae chitinase Lpchi1 and identification of its potential role in the biocontrol of root-knot nematode Meloidogyne incognita.
Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia.
Comparative analysis of shrimp (Penaeus vannamei) miRNAs expression profiles during WSSV infection under experimental conditions and in pond culture.
Comparative proteomic analysis of the sweetpotato provides insights into response mechanisms to Fusarium oxysporum f. sp. batatas.
Comparison of protein profiles and enzymes in non-mycorrhizal and mycorrhizal roots of Pennisetum pedicellatum.
Conferred resistance to Botrytis cinerea in Lilium by overexpression of the RCH10 chitinase gene.
Coordinated expression of defense-related genes by TMV infection or salicylic acid treatment in tobacco.
Crystallization and preliminary crystallographic analysis of a chitinase from Clonostachys rosea.
Dataset on recombinant expression of an ancient chitinase gene from different species of Leishmania parasites in bacteria and in Spodoptera frugiperda cells using baculovirus.
Defense Responses in Infected and Elicited Cucumber (Cucumis sativus L.) Hypocotyl Segments Exhibiting Acquired Resistance.
Deletion of the Autographa californica nucleopolyhedrovirus chitinase KDEL motif and in vitro and in vivo analysis of the modified virus.
Development of a high-efficiency gene knockout system for Pochonia chlamydosporia.
Developmental and Pathogen-Induced Activation of the Arabidopsis Acidic Chitinase Promoter.
Differential expression of eight chitinase genes in Medicago truncatula roots during mycorrhiza formation, nodulation, and pathogen infection.
Differential induction and accumulation of beta-1,3-glucanase and chitinase isoforms in soybean hypocotyls and leaves after compatible and incompatible infection with Phytophthora megasperma f.sp. glycinea.
Disruption of the gene which encodes a serodiagnostic antigen and chitinase of the human fungal pathogen Coccidioides immitis.
Distribution of chitinase in guinea pig tissues and increases in levels of this enzyme after systemic infection with Aspergillus fumigatus.
DNA immunisation with Onchocerca volvulus chitinase induces partial protection against challenge infection with L3 larvae in mice.
Dual function of a secreted fungalysin metalloprotease in Ustilago maydis.
Effect of chitinase antisense RNA expression on disease susceptibility of Arabidopsis plants.
Effect of geminivirus infection and Bemisia infestation on accumulation of pathogenesis-related proteins in tomato.
Effect of Introducing Chitinase Gene on the Resistance of Tuber Mustard against White Mold.
Effects of enhanced UV-B radiation on the interaction between rice and Magnaporthe oryzae in Yuanyang terrace.
Effects of Listeria monocytogenes EGD-e and Salmonella enterica ser. Typhimurium LT2 chitinases on intracellular survival in Dictyostelium discoideum and mammalian cell lines.
Effects of Rhizoctonia infection and drought on peroxidase and chitinase activity in Norway spruce (Picea abies).
Endochitinase CHI2 of the biocontrol fungus Metarhizium anisopliae affects its virulence toward the cotton stainer bug Dysdercus peruvianus.
Ethylene: Symptom, Not Signal for the Induction of Chitinase and beta-1,3-Glucanase in Pea Pods by Pathogens and Elicitors.
Evaluation of recombinant chitinase and SXP1 antigens as antimicrofilarial vaccines.
Evidence of alternative splicing of the chi2 chitinase gene from Metarhizium anisopliae.
Expression of a chitinase gene and lysis of the host cell wall during Chlorella virus CVK2 infection.
Expression of heterologous lycopene ?-cyclase gene in flax can cause silencing of its endogenous counterpart by changes in gene-body methylation and in ABA homeostasis mechanism.
Functional and Promoter Analysis of ChiIV3, a Chitinase of Pepper Plant, in Response to Phytophthora capsici Infection.
Galectins, Eosinophiles, and Macrophages May Contribute to Schistosoma japonicum Egg-Induced Immunopathology in a Mouse Model.
Gene expression analysis of the biocontrol fungus Trichoderma harzianum in the presence of tomato plants, chitin, or glucose using a high-density oligonucleotide microarray.
Genes upregulated in human fetal membranes by infection or labor.
Genetic polymorphisms in molecules of innate immunity and susceptibility to infection with Wuchereria bancrofti in South India.
Genome-wide association study in two populations to determine genetic variants associated with Toxoplasma gondii infection and relationship to schizophrenia risk.
Genome-wide survey for baculoviral host homologs using the Bombyx genome sequence.
Greenhouse and field testing of transgenic wheat plants stably expressing genes for thaumatin-like protein, chitinase and glucanase against Fusarium graminearum.
High-level expression of a tobacco chitinase gene in Nicotiana sylvestris. Susceptibility of transgenic plants to Cercospora nicotianae infection.
Hydrogen peroxide regulates elicitor PB90-induced cell death and defense in non-heading Chinese cabbage.
Identification and characterization of a new soybean promoter induced by Phakopsora pachyrhizi, the causal agent of Asian soybean rust.
Identification and preliminary characterization of a chitinase gene in the Autographa californica nuclear polyhedrosis virus genome.
Identification of chitinase as the immunodominant filarial antigen recognized by sera of vaccinated rodents.
Identification of Critical Host Mitochondrion-Associated Genes during Ehrlichia chaffeensis Infections.
Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki strain E. IV. Persistence of immunity and a note as to differing complement-fixation antigen requirements in post-infection and post-vaccination sera.
Immunolocalization of a class III chitinase in two muskmelon cultivars reacting differently to Fusarium oxysporum f. sp. melonis.
Immunomodulation of Host Chitinase 3-Like 1 During a Mammary Pathogenic Escherichia coli Infection.
Improved Carica papaya tolerance to carmine spider mite by the expression of Manduca sexta chitinase transgene.
Increased chitotriosidase activity in serum of leprosy patients: Association with bacillary leprosy.
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS.
Induced resistance in Yali pear (Pyrus bretschneideri Rehd.) fruit against infection of Penicillium expansum by postharvest infiltration of acibenzolar-S-methyl.
Induction and purification of chitinase in Brassica napus L. ssp. oleifera infected with Phoma lingam.
Induction by pathogen, salt and drought of a basic class II chitinase mRNA and its in situ localization in pepper (Capsicum annuum).
Induction of chitinase in response to Aspergillus infection in sorghum (Sorghum bicolor (L) Moench).
Induction of Defense Responses in Cucumber Plants by Using the Cell-free Filtrate of the Plant Growth-Promoting Fungus Penicillium simplicissimum GP17-2.
Induction of different chitinase and beta-1,3-glucanase isoenzymes in sunflower (Helianthus annuus L.) seedlings in response to infection by Plasmopara halstedii.
Induction of Direct or Priming Resistance against Botrytis cinerea in Strawberries by ?-Aminobutyric Acid and Their Effects on Sucrose Metabolism.
Induction of resistance in host against the infection of leaf blight pathogen (Alternaria palandui) in onion (Allium cepa var aggregatum).
Inflammation during Schistosoma haematobium infection and anti-allergy in pre-school-aged children living in a rural endemic area in Zimbabwe.
Influence of the mouse Bcg, Tbc-1 and xid genes on resistance and immune responses to tuberculosis infection and efficacy of bacille Calmette-Guérin (BCG) vaccination.
Inheritance, expression, and silencing of a chitinase transgene in rice.
Involvement of ethylene biosynthesis and perception in the susceptibility of citrus fruits to Penicillium digitatum infection and the accumulation of defence-related mRNAs.
Isoform patterns of chitinase and beta-1,3-glucanase in maturing corn kernels (Zea mays L.) associated with Aspergillus flavus milk stage infection.
LeCTR2, a CTR1-like protein kinase from tomato, plays a role in ethylene signalling, development and defence.
Legionella pneumophila type II secretome reveals unique exoproteins and a chitinase that promotes bacterial persistence in the lung.
Melatonin Mitigates the Infection of Colletotrichum gloeosporioides via Modulation of the Chitinase Gene and Antioxidant Activity in Capsicum annuum L.
Metarhizium anisopliae chitinase CHIT30 is involved in heat-shock stress and contributes to virulence against Dysdercus peruvianus.
Molecular and immunohistochemical characterization of the chitinase gene from Pieris rapae granulovirus.
Molecular characterization of plantain class i chitinase gene and its expression in response to infection by Gloeosporium musarum Cke and Massee and other abiotic stimuli.
Molecular mechanism of BjCHI1-mediated plant defense against Botrytis cinerea infection.
Molecular size and net charge of pathogenesis-related enzymes from barley (Hordeum vulgare L., v. Karat) infected with Drechslera teres f. teres (Sacch.) Shoem.
Multitrophic interactions of the silverleaf whitefly, host plants, competing herbivores, and phytopathogens.
N-linked glycans located in the pro-region of Bombyx mori nucleopolyhedrovirus V-CATH are essential for the proper folding of V-CATH and V-CHIA.
Nematocidal activity of extracellular enzymes produced by the nematophagous fungus Duddingtonia flagrans on cyathostomin infective larvae.
Non-canonical fungal G-protein coupled receptors promote Fusarium head blight on wheat.
Pepper gene encoding a basic class II chitinase is inducible by pathogen and ethephon.
Peptidoglycan from fermentation by-product triggers defense responses in grapevine.
Phyllosticta musarum Infection-Induced Defences Suppress Anthracnose Disease Caused by Colletotrichum musae in Banana Fruits cv 'Embul'.
Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis.
Primary structure and expression of acidic (class II) chitinase in potato.
Primary structure and expression of mRNAs encoding basic chitinase and 1,3-beta-glucanase in potato.
Production and regulation of extracellular chitinase from the entomopathogenic fungus Isaria fumosorosea.
Prolactin induces chitotriosidase gene expression in human monocyte-derived macrophages.
Proteomic analysis of tobacco mosaic virus-infected tomato (Lycopersicon esculentum M.) fruits and detection of viral coat protein.
Protocol: transient expression system for functional genomics in the tropical tree Theobroma cacao L.
Pulmonary cryptococcosis induces chitinase in the rat.
Quantitative changes in serum concentration of bovine gut chitinase in Theileria infection.
Rapid detection of phylloplane bacterium Enterobacter cloacae based on chitinase gene transformation and lytic infection by specific bacteriophages.
Real-time quantitative RT-PCR assay of gene expression in plant roots during fungal pathogenesis.
Refractoriness of Sergentomyia schwetzi to Leishmania spp is mediated by the peritrophic matrix.
Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae.
Regulation of Chitinase in Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae) During Infection by Heliothis virescens ascovirus 3h (HvAV-3h).
Reprogramming the chiA expression profile of Autographa californica multiple nucleopolyhedrovirus.
Rickettsia-like organisms and chitinase production in relation to transmission of trypanosomes by tsetse flies.
Sequential Expression of Bacterial Virulence and Plant Defense Genes During Infection of Tomato with Clavibacter michiganensis subsp. michiganensis
Sequential expression of bacterial virulence and plant defense genes during infection of tomato with Clavibacter michiganensis subsp. michiganensis.
Serum chitotriosidase levels in cancer patients undergoing high dose chemotherapy and stem cell transplantation.
Signal transduction by Tga3, a novel G protein alpha subunit of Trichoderma atroviride.
Studies on the Cloning and Expression of Bbchit1 Gene of Beauveria bassiana NCIM 1216.
Surface ?-1,3-Glucan Facilitates Fungal Stealth Infection by Interfering with Innate Immunity in Plants.
Systemic acquired resistance induced by BTH in papaya
The effect of chitosan and Bion on resistance to pink snow mould in perennial ryegrass and winter wheat.
The Journal of Epithelial Biology and Pharmacology.
The Listeria monocytogenes ChiA Chitinase Enhances Virulence through Suppression of Host Innate Immunity.
The LysM Receptor-Like Kinase LysM RLK1 Is Required to Activate Defense and Abiotic-Stress Responses Induced by Overexpression of Fungal Chitinases in Arabidopsis Plants.
The microbial environment and intestinal nematode infections of Heligmosomoides polygyrus in laboratory mice.
The promoter of the potato chitinase C gene directs expression to epidermal cells.
The role of chitosan in protection of soybean from sudden death syndrome caused by Fusarium solani f. sp. glycines.
The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis.
The symptoms of infection by Bacillus thuringiensis + Chitinase formulation in larvae of Choristoneura fumiferana.
Tobacco-expressed Brassica juncea chitinase BjCHI1 shows antifungal activity in vitro.
Toxicological and biochemical basis of synergism between the entomopathogenic fungus Lecanicillium muscarium and the insecticide matrine against Bemisia tabaci (Gennadius).
Transcriptomic profiling of susceptible and resistant flax seedlings after Fusarium oxysporum lini infection.
Transgenic wheat expressing a barley class II chitinase gene has enhanced resistance against Fusarium graminearum.
Ultrastructural observation of Botrytis cinerea and physical changes in resistant and susceptible grapevines.
Virulence Vs. Immunomodulation: Roles of the Paracoccin Chitinase and Carbohydrate-Binding Sites in Paracoccidioides brasiliensis Infection.
[Cloning and expression of the chitinase gene Chit1 from entomopathogenic fungus Nomuraea rileyi CQ]
[Effect of multi-generation culture on virulence of Lecanicilliurn lecanii in different media]
[Further study of hantavirus circulation in the Russian Federation]
[Intercellular 27 kD protein is a chitinase induced by water stress or Pseudoperonospora cubensis in cucumber leaves]
[Studies on recombinant chitinase and SXP-1 antigens as antimicrofilarial vaccines]
[Survival of helminth eggs in the wastewater mud in the sludge beds of Chita waterworks]
[The relationship between activities of chitinase and beta-1,3-glucanase and resistance to rhizomania in sugar beet]
[Tuberculosis infection rate among adult population of the Chernyshevsk district of the Chita region]
Inflammatory Bowel Diseases
Chitinase 3-like 1 Synergistically Activates IL6-mediated STAT3 Phosphorylation in Intestinal Epithelial Cells in Murine Models of Infectious Colitis.
Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseases.
Faecal chitinase 3-like-1: a novel biomarker of disease activity in paediatric inflammatory bowel disease.
Novel methylxanthine derivative-mediated anti-inflammatory effects in inflammatory bowel disease.
Potential association between TLR4 and chitinase 3-like 1 (CHI3L1/YKL-40) signaling on colonic epithelial cells in inflammatory bowel disease and colitis-associated cancer.
Potential role of chitinase 3-like-1 in inflammation-associated carcinogenic changes of epithelial cells.
Serum concentrations of fibrosis markers in children with inflammatory bowel disease.
Influenza, Human
[Clinical aspects of influenza in 1965 (based on data of the Chita Hospital and military unit hospitals]
[Pathological anatomy in A/H1N1 influenza]
Insulin Resistance
Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease.
Women with polycystic ovary syndrome have increased plasma chitotriosidase activity: a pathophysiological link between inflammation and impaired insulin sensitivity?
Insulinoma
Antifreeze Protein Prolongs the Life-Time of Insulinoma Cells during Hypothermic Preservation.
Intestinal Volvulus
A computational analysis of the binding mode of closantel as inhibitor of the Onchocerca volvulus chitinase: insights on macrofilaricidal drug design.
Chitinase genes expressed by infective larvae of the filarial nematodes, Acanthocheilonema viteae and Onchocerca volvulus.
Chitinase is stored and secreted from the inner body of microfilariae and has a role in exsheathment in the parasitic nematode Brugia malayi.
Design, synthesis, and biological activities of closantel analogues: structural promiscuity and its impact on Onchocerca volvulus.
DNA immunisation with Onchocerca volvulus chitinase induces partial protection against challenge infection with L3 larvae in mice.
Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting.
Effect of Onchocerca volvulus chitinase on MUC5B expression in human airway epithelial cells.
Expression and secretion of a larval-specific chitinase (family 18 glycosyl hydrolase) by the infective stages of the parasitic nematode, Onchocerca volvulus.
Human immune responses to infective stage larval-specific chitinase of filarial parasite, Onchocerca volvulus, Ov-CHI-1.
Identification of T helper cell-recognized epitopes in the chitinase of the filarial nematode Onchocerca volvulus.
Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.
Invasive Fungal Infections
Chitin, chitinase responses, and invasive fungal infections.
Iron Overload
Plasma chitotriosidase activity in beta-thalassemia major: a comparative study between Sicilian and Sardinian patients.
Plasma chitotriosidase activity in patients with beta-thalassemia.
Ischemic Stroke
24 bp duplication of CHIT1 gene is not correlated with coronary artery disease in Corsica Island (France).
Chitotriosidase in patients with acute ischemic stroke.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Serum Chitotriosidase Activity, a Marker of Activated Macrophages, Predicts New Cardiovascular Events Independently of C-Reactive Protein.
Latex Hypersensitivity
Latex-allergic patients sensitized to the major allergen hevein and hevein-like domains of class I chitinases show no increased frequency of latex-associated plant food allergy.
Legionnaires' Disease
Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation.
Leishmaniasis
Dataset on recombinant expression of an ancient chitinase gene from different species of Leishmania parasites in bacteria and in Spodoptera frugiperda cells using baculovirus.
Molecular characterization of Llchit1, a midgut chitinase cDNA from the leishmaniasis vector Lutzomyia longipalpis.
Leishmaniasis, Visceral
Alternative splicing originates different domain structure organization of Lutzomyia longipalpis chitinases.
Leprosy
Increased chitotriosidase activity in serum of leprosy patients: Association with bacillary leprosy.
Leukemia, Myeloid, Acute
Common genetic variants in the interleukin-6 and chitotriosidase genes are associated with the risk for serious infection in children undergoing therapy for acute myeloid leukemia.
Leukodystrophy, Globoid Cell
Comparison between the biochemical properties of plasma chitotriosidase from normal individuals and from patients with Gaucher disease, GM1-gangliosidosis, Krabbe disease and heterozygotes for Gaucher disease.
Lipidoses
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
Liver Abscess
Chitinase-gene-based analysis of the genetic variability among the clinical isolates of
Two different chitinase genotypes in a patient with an amebic liver abscess: a case report.
Liver Abscess, Amebic
Two different chitinase genotypes in a patient with an amebic liver abscess: a case report.
Liver Cirrhosis
A noninvasive diagnostic model for significant liver fibrosis in patients with chronic hepatitis B based on CHI3L1 and routine clinical indicators.
Changes of serum Chitinase 3-like 1 levels correlate with changes of liver fibrosis measured by the two established quantitative methods in chronic hepatitis B patients following antiviral therapy.
Chitinase 3-like 1 deficiency ameliorates liver fibrosis by promoting hepatic macrophage apoptosis.
Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis.
Decrease in Chitinase 3-Like Protein 1 Levels Reflects Improvement in Liver Fibrosis after HCV Eradication.
The clinical significance of serum chitinase 3-like 1 in hepatitis B-related chronic liver diseases.
Liver Diseases
A Rare Cause of Elevated Chitotriosidase Activity: Glycogen Storage Disease Type IV.
Adiponectin and the steatosis marker Chi3L1 decrease following switch to raltegravir compared to continued PI/NNRTI-based antiretroviral therapy.
An uncommon cause of early infantile liver disease and raised chitotriosidase.
Association of chitotriosidase genotype with the development of non-alcoholic fatty liver disease.
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Evaluation of Chitinase 3-like 1 (CHI3L1) as a noninvasive biomarker of hepatic fibrosis in patients with Hepatitis B virus-related compensated chronic liver disease.
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
Potential role of chitotriosidase gene in nonalcoholic Fatty liver disease evolution.
Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease.
Serum YKL-40 levels and chitotriosidase activity in patients with beta-thalassemia major.
The clinical significance of serum chitinase 3-like 1 in hepatitis B-related chronic liver diseases.
Liver Neoplasms
Mortality from liver disease among Italian vinyl chloride monomer/polyvinyl chloride manufacturers.
Serum chitinase activity prognosticates metastasis of colorectal cancer.
Lung Diseases
Chitinase 3-like 1 polymorphisms and risk of chronic obstructive pulmonary disease and asthma in a Chinese population.
Chitinase 3-like-1 and its receptors in Hermansky-Pudlak syndrome-associated lung disease.
Chitinase activation in patients with fungus-associated cystic fibrosis lung disease.
Chitotriosidase activity in patients with interstitial lung diseases.
Chitotriosidase activity in sarcoidosis and some other pulmonary diseases.
Chitotriosidase: a marker and modulator of lung disease.
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Duplication in CHIT1 gene and the risk for Aspergillus lung disease in CF patients.
Macrophage chitinase 1 stratifies chronic obstructive lung disease.
Marked differences in tissue-specific expression of chitinases in mouse and man.
Successful within-patient dose escalation of olipudase alfa in acid sphingomyelinase deficiency.
Lung Diseases, Fungal
Association of 24 bp Duplication of Human CHIT1 Gene with Asthma in a Heterozygous Population of North India: A Case-Control Study.
Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection.
Lung Diseases, Interstitial
Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-?1 Signaling.
Chitinase 1 regulates pulmonary fibrosis by modulating TGF-?/SMAD7 pathway via TGFBRAP1 and FOXO3.
Chitotriosidase activity in patients with interstitial lung diseases.
Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD.
Clinical Significance of Serum Chitotriosidase Level in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease.
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Lung Injury
Chitotriosidase is a biomarker for the resistance to World Trade Center lung injury in New York City firefighters.
Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury.
Lung Neoplasms
Chitotriosidase activity in sarcoidosis and some other pulmonary diseases.
Elevated Serum Concentration of Chitinase 3-Like 1 is an Independent Prognostic Biomarker for Poor Survival in Lung Cancer Patients.
Increased expression of chitinase 3-like 1 is a prognosis marker for non-small cell lung cancer correlated with tumor angiogenesis.
Stat3 downstream gene product chitinase 3-like 1 is a potential biomarker of inflammation-induced lung cancer in multiple mouse lung tumor models and humans.
The diagnostic value of tumor markers in bronchoalveolar lavage fluid for the peripheral pulmonary carcinoma.
[Serum activity of chitotriosidase, lysozyme and cathepsin H in patients with lung cancer and patients with inflammatory exudate (preliminary report)]
Lymphatic Metastasis
Serum chitinase activity prognosticates metastasis of colorectal cancer.
Lymphedema
Polymorphisms of innate immunity genes and susceptibility to lymphatic filariasis.
Lymphocytic Choriomeningitis
[Complement-fixation antigen in lymphocytic choriomeningitis prepared by bentonine purification.]
Lymphoma
Knockdown of Chitinase 3-Like-1 Inhibits Cell Proliferation, Promotes Apoptosis, and Enhances Effect of Anti-Programmed Death Ligand 1 (PD-L1) in Diffuse Large B Cell Lymphoma Cells.
Potential Diagnostic Value of the Peripheral Blood Mononuclear Cell Transcriptome From Cattle With Bovine Tuberculosis.
Lymphoma, B-Cell
Knockdown of Chitinase 3-Like-1 Inhibits Cell Proliferation, Promotes Apoptosis, and Enhances Effect of Anti-Programmed Death Ligand 1 (PD-L1) in Diffuse Large B Cell Lymphoma Cells.
Potential Diagnostic Value of the Peripheral Blood Mononuclear Cell Transcriptome From Cattle With Bovine Tuberculosis.
Lymphoma, Large B-Cell, Diffuse
Knockdown of Chitinase 3-Like-1 Inhibits Cell Proliferation, Promotes Apoptosis, and Enhances Effect of Anti-Programmed Death Ligand 1 (PD-L1) in Diffuse Large B Cell Lymphoma Cells.
Lymphoma, Non-Hodgkin
Chitotriosidase as a new marker of macrophage stimulation in a tumor model treated with cyclophosphamide and Ukrain.
Lysosomal Storage Diseases
A Rare Cause of Elevated Chitotriosidase Activity: Glycogen Storage Disease Type IV.
Allelic Frequency of a 24-bp Duplication in Exon 10 of the CHIT1 Gene in the General Iranian Population.
Biochemical and Molecular Chitotriosidase Profiles in Patients with Gaucher Disease Type 1 in Minas Gerais, Brazil: New Mutation in CHIT1 Gene.
Chitotriosidase activity as additional biomarker in the diagnosis of lysosomal storage diseases.
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
Human chitotriosidase: a potential new marker of sarcoidosis severity.
Identification and use of biomarkers in Gaucher disease and other lysosomal storage diseases.
Plasma chitotriosidase in lysosomal storage diseases.
[Chitotriosidase of human macrophages and mammalian chitinases: biological functions and abnormalities in pathology]
Malaria
A fine functional homology between chitinases from host and parasite is relevant for malaria transmissibility.
An anti-Chitinase malaria transmission-blocking single-chain antibody as an effector molecule for creating a Plasmodium falciparum-refractory mosquito.
Bioconversion of Chitin to Bioactive Chitooligosaccharides: Amelioration and Coastal Pollution Reduction by Microbial Resources.
Characterization of a novel gut-specific chitinase gene from the human malaria vector Anopheles gambiae.
Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children.
Chitinases of the avian malaria parasite Plasmodium gallinaceum, a class of enzymes necessary for parasite invasion of the mosquito midgut.
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population.
Comparative genomic analysis of chitinase and chitinase-like genes in the African malaria mosquito (Anopheles gambiae).
Different effects of modulation of mosquito (Diptera:Culicidae) trypsin activity on the infectivity of two human malaria (Hemosporidia:Plasmodidae) parasites.
Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study.
Enzymatic characterization of the Plasmodium vivax chitinase, a potential malaria transmission-blocking target.
High levels of human chitotriosidase hinder the formation of peritrophic membrane in anopheline vectors.
Hygiene hypothesis: innate immunity, malaria and multiple sclerosis.
Identification of an eosinophil chemotactic factor from anopheline mosquitoes as a chitinase family protein.
Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes.
Malaria parasite chitinase and penetration of the mosquito peritrophic membrane.
Molecular identification of the chitinase genes in Plasmodium relictum.
Monoclonal antibody against the Plasmodium falciparum chitinase, PfCHT1, recognizes a malaria transmission-blocking epitope in Plasmodium gallinaceum ookinetes unrelated to the chitinase PgCHT1.
Plasma chitotriosidase activity and malaria.
Plasma chitotriosidase activity in acute Plasmodium falciparum malaria.
Plasmodium ookinete-secreted chitinase and parasite penetration of the mosquito peritrophic matrix.
Plasmodium ookinete-secreted proteins secreted through a common micronemal pathway are targets of blocking malaria transmission.
Plasmodium: parasite chitinase and its role in malaria transmission.
Prolactin induces chitotriosidase gene expression in human monocyte-derived macrophages.
Synthetic propeptide inhibits mosquito midgut chitinase and blocks sporogonic development of malaria parasite.
The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences.
The Journal of Epithelial Biology and Pharmacology.
Transmission-blocking activity of a chitinase inhibitor and activation of malarial parasite chitinase by mosquito protease.
Malaria, Avian
An anti-Chitinase malaria transmission-blocking single-chain antibody as an effector molecule for creating a Plasmodium falciparum-refractory mosquito.
Chitinases of the avian malaria parasite Plasmodium gallinaceum, a class of enzymes necessary for parasite invasion of the mosquito midgut.
Disruption of Plasmodium falciparum chitinase markedly impairs parasite invasion of mosquito midgut.
Knockout of the rodent malaria parasite chitinase pbCHT1 reduces infectivity to mosquitoes.
Molecular identification of the chitinase genes in Plasmodium relictum.
The chitinase PfCHT1 from the human malaria parasite Plasmodium falciparum lacks proenzyme and chitin-binding domains and displays unique substrate preferences.
Malaria, Cerebral
Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children.
Malaria, Falciparum
Chitinase 3-like 1 is induced by Plasmodium falciparum malaria and predicts outcome of cerebral malaria and severe malarial anaemia in a case-control study of African children.
Plasma chitotriosidase activity in acute Plasmodium falciparum malaria.
Prolactin induces chitotriosidase gene expression in human monocyte-derived macrophages.
Measles
The measles specificity of the lymphocyte stimulation test with measles complement-fixation antigen.
Meibomian Gland Dysfunction
Acidic mammalian chitinase in dry eye conditions.
Melanoma
Incremental biomarker and clinical outcomes after switch from enzyme therapy to eliglustat substrate reduction therapy in Gaucher disease.
Melanoma Associated Chitinase 3-Like 1 Promoted Endothelial Cell Activation and Immune Cell Recruitment.
Role of chitinase 3-like-1 and semaphorin 7a in pulmonary melanoma metastasis.
Metabolic Diseases
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Motor Neuron Disease
Cerebrospinal fluid phosphorylated neurofilament heavy chain and chitotriosidase in primary lateral sclerosis.
CSF chitinase proteins in amyotrophic lateral sclerosis.
Mucolipidoses
Type II sialidosis: review of the clinical spectrum and identification of a new splicing defect with chitotriosidase assessment in two patients.
Multiple Myeloma
Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy.
Multiple Sclerosis
Breast regression protein-39 is not required for experimental autoimmune encephalomyelitis induction.
Cerebrospinal fluid chitinase 3-like 1 levels are associated with conversion to multiple sclerosis.
Cerebrospinal fluid chitinase-3-like 2 and chitotriosidase are potential prognostic biomarkers in early multiple sclerosis.
Cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain predict multiple sclerosis development and disability after optic neuritis.
CHIT1 at Diagnosis Reflects Long-Term Multiple Sclerosis Disease Activity.
Chitinase 3-like 1 is associated with the response to interferon-beta treatment in multiple sclerosis.
Chitinase 3-like 1 is neurotoxic in primary cultured neurons.
Chitinase 3-like 1 is not a target antigen in patients with multiple sclerosis.
Chitinase 3-like 1 plasma levels are increased in patients with progressive forms of multiple sclerosis.
Chitinase 3-like 1: prognostic biomarker in clinically isolated syndromes.
Chitinase 3-like proteins as diagnostic and prognostic biomarkers of multiple sclerosis.
Chitinase effects on immune cell response in neuromyelitis optica and multiple sclerosis.
Chitotriosidase activity in controls and multiple sclerosis.
Chitotriosidase in multiple sclerosis.
Cognitive impairment in early stages of multiple sclerosis is associated with high cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain.
CSF Chitinase 3-Like 2 Is Associated With Long-term Disability Progression in Patients With Progressive Multiple Sclerosis.
Determination of chitinase 3-like 1 in cerebrospinal fluid in multiple sclerosis and other neurological diseases.
Exacerbation of experimental autoimmune encephalomyelitis in the absence of breast regression protein 39/chitinase 3-like 1.
Extreme Stability of Chitotriosidase in Cerebrospinal Flulid makes it a Suitable Marker for Microglial Activation in Clinical Trials.
Increased cerebrospinal fluid chitotriosidase index in patients with multiple sclerosis.
Intrathecal chitotriosidase and the outcome of multiple sclerosis.
Neurofilament light chain and oligoclonal bands are prognostic biomarkers in radiologically isolated syndrome.
Peripheral chitotriosidase in patients with multiple sclerosis.
Plasma chitotriosidase activity in multiple sclerosis.
Protein-Based Classifier to Predict Conversion from Clinically Isolated Syndrome to Multiple Sclerosis.
Muscle Cramp
Proteins induced by telomere dysfunction are associated with human IgA nephropathy.
Muscular Atrophy, Spinal
Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy.
Mycetoma
A Polymorphism in the Chitotriosidase Gene Associated with Risk of Mycetoma Due to Madurella mycetomatis Mycetoma--A Retrospective Study.
Mycoses
(123)I-Labeled chitinase as specific radioligand for in vivo detection of fungal infections in mice.
A Class IV Chitinase Is Up-Regulated by Fungal Infection and Abiotic Stresses and Associated with Slow-Canker-Growth Resistance to Cronartium ribicola in Western White Pine (Pinus monticola).
A class IV chitinase is up-regulated by fungal infection and abiotic stresses and associated with slow-canker-growth resistance to Cronartium ribicola in western white pine (Pinus monticola).
A study of some biochemical and histopathological responses of wet-stored recalcitrant seeds of Avicennia marina infected by Fusarium moniliforme.
Activation of a Bean Chitinase Promoter in Transgenic Tobacco Plants by Phytopathogenic Fungi.
Antifungal genes expressed in transgenic pea (Pisum sativum L.) do not affect root colonization of arbuscular mycorrhizae fungi.
BjMYB1, a transcription factor implicated in plant defence through activating BjCHI1 chitinase expression by binding to a W-box-like element.
CHIT1 mutations: genetic risk factor for severe asthma with fungal sensitization?
Chitin nanofibers trigger membrane bound defense signaling and induce elicitor activity in plants.
Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection.
Chitin, chitinase responses, and invasive fungal infections.
Chitinases in biological control.
Chitinolytic assay of indigenous Trichoderma isolates collected from different geographical locations of Chhattisgarh in Central India.
Chitotriosidase and gene therapy for fungal infections.
Chitotriosidase deficiency in survivors of Candida sepsis.
Chitotriosidase in neonates with fungal and bacterial infections.
Co-expression of chimeric chitinase and a polygalacturonase-inhibiting protein in transgenic canola (Brassica napus) confers enhanced resistance to Sclerotinia sclerotiorum.
Cuticle-induced endo/exoacting chitinase CHIT30 from Metarhizium anisopliae is encoded by an ortholog of the chi3 gene.
Defence-related gene expression in transgenic lemon plants producing an antimicrobial Trichoderma harzianum endochitinase during fungal infection.
Diagnostic value of fluorescein-labeled chitinase staining in formalin-fixed and paraffin-embedded tissues of fungal disease.
Differential physiological and biochemical responses of Quercus infectoria and Q. libani to drought and charcoal disease.
Electrical Stimulation Enhances Plant Defense Response in Grapevine through Salicylic Acid-Dependent Defense Pathway.
Endochitinase CHI2 of the biocontrol fungus Metarhizium anisopliae affects its virulence toward the cotton stainer bug Dysdercus peruvianus.
Enhanced resistance to Sclerotinia sclerotiorum in Brassica napus by co-expression of defensin and chimeric chitinase genes.
Ethylene: Symptom, Not Signal for the Induction of Chitinase and beta-1,3-Glucanase in Pea Pods by Pathogens and Elicitors.
Expression analysis of chitinase upon challenge inoculation to Alternaria wounding and defense inducers in Brassica juncea.
Expression of a fungal endochitinase gene in transgenic tomato and tobacco results in enhanced tolerance to fungal pathogens.
Family 19 chitinase of Streptomyces griseus HUT6037 increases plant resistance to the fungal disease.
Field performance of chitinase transgenic silver birches (Betula pendula): resistance to fungal diseases.
Genetic transformation of pigeonpea with rice chitinase gene.
Heterologous expression of genes mediating enhanced fungal resistance in transgenic wheat.
Human chitotriosidase CHIT1 cross reacts with mammalian-like substrates.
Identification of fungus-responsive cis-acting element in the promoter of Brassica juncea chitinase gene, BjCHI1.
Isolation and characterization of two chitinase-encoding genes (cts1, cts2) from the fungus Coccidioides immitis.
Molecular cloning and characterization of a pea chitinase gene expressed in response to wounding, fungal infection and the elicitor chitosan.
Molecular cloning and characterization of the promoter for the multiple stress-inducible gene BjCHI1 from Brassica juncea.
Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome.
Proteome responses to individual pathogens and abiotic conditions in rice seedlings.
Pulmonary cryptococcosis induces chitinase in the rat.
Radiolabeled white blood cells and direct targeting of micro-organisms for infection imaging.
Searching for new-type antifungal drugs (an outline for possible new strategies).
Spatial distribution of chitinases and beta-1,3-glucanase transcripts in bean arbuscular mycorrhizal roots under low and high soil phosphate conditions.
The chitinase gene (Bbchit1) from Beauveria bassiana enhances resistance to Cytospora chrysosperma in Populus tomentosa Carr.
The Lupinus albus class-III chitinase gene, IF3, is constitutively expressed in vegetative organs and developing seeds.
The Role of Fungi in the Etiology of Multiple Sclerosis.
Transformants of Metarhizium anisopliae sf. anisopliae overexpressing chitinase from Metarhizium anisopliae sf. acridum show early induction of native chitinase but are not altered in pathogenicity to Manduca sexta.
Transformation of blackgram (Vigna mungo (L.) Hepper) by barley chitinase and ribosome-inactivating protein genes towards improving resistance to Corynespora leaf spot fungal disease.
Truncation of class IV chitinases from Arabidopsis by secreted fungal proteases.
[Lytic enzymes of Trichoderma and their role in protecting plants from fungal diseases]
Myocardial Infarction
Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events.
Serum Chitotriosidase Activity in Acute Coronary Syndrome.
Serum Chitotriosidase Activity, a Marker of Activated Macrophages, Predicts New Cardiovascular Events Independently of C-Reactive Protein.
Myocardial Ischemia
24 bp duplication of CHIT1 gene is not correlated with coronary artery disease in Corsica Island (France).
Serum chitotriosidase activity is increased in subjects with atherosclerosis disease.
[Effect of statins on activity of matrix metalloproteases and serum concentration of cystatin C in patients with various risk of development of ischemic heart disease and in patients after coronary artery bypass surgery].
Narcolepsy
Cerebrospinal fluid biomarkers of neurodegeneration are decreased or normal in narcolepsy.
Cerebrospinal Fluid Biomarkers of Neurodegeneration Are Decreased or Normal in Narcolepsy.
Nasal Polyps
Chitinolytic activity in nasal polyps.
Expression and role of acidic mammalian chitinase and eotaxin-3 in chronic rhinosinusitis with nasal polyps.
Increased expression of acidic mammalian chitinase in chronic rhinosinusitis with nasal polyps.
Role of acidic mammalian chitinase and chitotriosidase in nasal polyps.
Nematode Infections
Chitinase and Fizz family members are a generalized feature of nematode infection with selective upregulation of Ym1 and Fizz1 by antigen-presenting cells.
Chitotriosidase deficiency is not associated with human hookworm infection in a Papua New Guinean population.
Neoplasm Metastasis
Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through ?-catenin/Erk/Akt signaling in gastric cancer.
Chitotriosidase, a marker of innate immunity, is elevated in patients with primary breast cancer.
Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer.
Increased expression of Chitinase 3-like 1 and microvessel density predicts metastasis and poor prognosis in clear cell renal cell carcinoma.
Key biomarkers within the colorectal cancer related inflammatory microenvironment.
M2 Macrophage Marker Chitinase 3-Like 2 (CHI3L2) Associates With Progression of Conventional Renal Cell Carcinoma.
Mobilization of epithelial mesenchymal transition genes distinguishes active from inactive lesional tissue in patients with ulcerative colitis.
RIG-like Helicase Regulation of Chitinase 3-like 1 Axis and Pulmonary Metastasis.
Role of chitinase 3-like-1 and semaphorin 7a in pulmonary melanoma metastasis.
Serum chitinase activity prognosticates metastasis of colorectal cancer.
SI-CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor-associated macrophages.
Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR-125a-3p-mediated up-regulation of USF1.
Neoplasms
?Np63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer.
An in vivo study of antifreeze protein adjuvant cryosurgery.
Astrogliosis Releases Pro-Oncogenic Chitinase 3-Like 1 Causing MAPK Signaling in Glioblastoma.
CHF5074 (CSP-1103) induces microglia alternative activation in plaque-free Tg2576 mice and primary glial cultures exposed to beta-amyloid.
CHI3L1 (YKL-40) is expressed in human gliomas and regulates the invasion, growth and survival of glioma cells.
CHI3L1 alleviate acute liver injury by inhibiting Th1 cells differentiation through STAT3 signaling pathway.
CHI3L1 promotes proliferation and improves sensitivity to cetuximab in colon cancer cells by down-regulating p53.
Chitinase 3 like 1 is associated with tumor angiogenesis in cervical cancer.
Chitinase 3 like 1 suppresses the stability and activity of p53 to promote lung tumorigenesis.
Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1? and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia.
Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization.
Chitinase 3-like 1 promotes macrophage recruitment and angiogenesis in colorectal cancer.
Chitinase 3-Like-1 (CHI3L1): a putative disease marker at the interface of proteomics and glycomics.
Chitinase 3-like-1 deficient donor splenocytes accentuated the pathogenesis of acute graft-versus-host diseases through regulating T cell expansion and type I inflammation.
Chitinase 3-like-1 expression in colonic epithelial cells as a potentially novel marker for colitis-associated neoplasia.
Chitinase induces lysis of MCF-7 cells in culture and of human breast cancer xenograft B11-2 in SCID mice.
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Chitotriosidase activity in sarcoidosis and some other pulmonary diseases.
Chitotriosidase as a new marker of macrophage stimulation in a tumor model treated with cyclophosphamide and Ukrain.
Chitotriosidase, a marker of innate immunity, is elevated in patients with primary breast cancer.
Chitotriosidase, interleukin-1 beta and tumor necrosis factor alpha levels in mild preeclampsia.
Clinical utility of chitotriosidase enzyme activity in nephropathic cystinosis.
Comparative Profiling of Metastatic 4T1- vs. Non-metastatic Py230-Based Mammary Tumors in an Intraductal Model for Triple-Negative Breast Cancer.
Comparison of the Adipose and Luminal Mammary Gland Compartment as Orthotopic Inoculation Sites in a 4T1-Based Immunocompetent Preclinical Model for Triple-Negative Breast Cancer.
Cytotoxicity against tumor cell lines and anti-inflammatory properties of chitinases from Calotropis procera latex.
Detection of bacterial chitinase activity in transformed plant tumour cells using a specific exochitinase substrate.
Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study.
Effect of interferon-gamma, interleukin-10, lipopolysaccharide and tumor necrosis factor-alpha on chitotriosidase synthesis in human macrophages.
Elevated Serum Concentration of Chitinase 3-Like 1 is an Independent Prognostic Biomarker for Poor Survival in Lung Cancer Patients.
Elevated YKL40 is associated with advanced prostate cancer (PCa) and positively regulates invasion and migration of PCa cells.
Flounder antifreeze peptides increase the efficacy of cryosurgery.
G721-0282 inhibits cell growth and induces apoptosis in human osteosarcoma through down-regulation of the STAT3 pathway.
Gene Encoding Chitinase 3-Like 1 Protein (CHI3L1) is a Putative Oncogene.
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
High Endogenous Expression of Chitinase 3-Like 1 and Excessive Epithelial Proliferation with Colonic Tumor Formation in MOLF/EiJ Mice.
hYKL-40 cancer biomarker electroanalysis in serum samples and model cell lysates: capacitive immunosensing compared with enzyme label immunosorbent assays (ELISA).
Increased expression of Chitinase 3-like 1 and microvessel density predicts metastasis and poor prognosis in clear cell renal cell carcinoma.
Increased expression of chitinase 3-like 1 is a prognosis marker for non-small cell lung cancer correlated with tumor angiogenesis.
Interferon-gamma, tumor necrosis factor-alpha, and lipopolysaccharide promote chitotriosidase gene expression in human macrophages.
Key biomarkers within the colorectal cancer related inflammatory microenvironment.
Linking molecular biomarkers with higher level condition indicators to identify effects of copper exposures on the endangered delta smelt (Hypomesus transpacificus).
Melanoma Associated Chitinase 3-Like 1 Promoted Endothelial Cell Activation and Immune Cell Recruitment.
Molecular Profiling for Predictors of Radiosensitivity in Patients with Breast or Head-and-Neck Cancer.
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Occupational exposure to gasoline in gasoline station male attendants promotes M1 polarization in macrophages.
Plasma level of chitinase 3-like 1 protein increases in patients with early Alzheimer's disease.
Polymorphisms in the CHIT1 gene: Associations with colorectal cancer.
Preoperative serum YKL-40 is a marker for detection and prognosis of endometrial cancer.
Profiling of a few immune responsive genes expressed in postlarvae of Fenneropenaeus indicus challenged with Vibrio harveyi D3.
Role of chitinase-like proteins in cancer.
Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis.
Roles of chitinase 3-like 1 in the development of cancer, neurodegenerative diseases, and inflammatory diseases.
Serum chitotriosidase levels in cancer patients undergoing high dose chemotherapy and stem cell transplantation.
Serum chitotriosidase: a circulating biomarker in polycythemia vera.
Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia.
SI-CLP inhibits the growth of mouse mammary adenocarcinoma by preventing recruitment of tumor-associated macrophages.
Stat3 downstream gene product chitinase 3-like 1 is a potential biomarker of inflammation-induced lung cancer in multiple mouse lung tumor models and humans.
Suppression of metastasis through inhibition of chitinase 3-like 1 expression by miR-125a-3p-mediated up-regulation of USF1.
Systems Biology-Derived Biomarkers to Predict Progression of Renal Function Decline in Type 2 Diabetes.
The chitinase 3-like protein human cartilage glycoprotein 39 inhibits cellular responses to the inflammatory cytokines interleukin-1 and tumour necrosis factor-alpha.
The Evaluation of AREG, MMP-2, CHI3L1, GFAP, and OPN Serum Combined Value in Astrocytic Glioma Patients' Diagnosis and Prognosis.
The expression of chitinase 3-like 1: a novel prognostic predictor for hepatocellular carcinoma.
The mechanism of the anticancer function of M1 macrophages and their use in the clinic.
The Role of CHI3L1 Expression in Angiogenesis in Invasive Ductal Breast Carcinoma.
Tissue Indices of Telomere Length and p53 in Patients with Different Gastrointestinal Tumors: Correlation with Clinicopathological Status.
Two closely related human members of chitinase-like family, CHI3L1 and CHI3L2, activate ERK1/2 in 293 and U373 cells but have the different influence on cell proliferation.
YKL-40 in the brain and cerebrospinal fluid of neurodegenerative dementias.
YKL-40 Protein Levels and Clinical Outcome of Human Endometrial Cancer.
[Adipose-derived stem cells promote the polarization from M1 macrophages to M2 macrophages].
[Serum activity of chitotriosidase, lysozyme and cathepsin H in patients with lung cancer and patients with inflammatory exudate (preliminary report)]
Neurodegenerative Diseases
Chitotriosidase (CHIT1) is increased in microglia and macrophages in spinal cord of amyotrophic lateral sclerosis and cerebrospinal fluid levels correlate with disease severity and progression.
Increased chitotriosidase 1 concentration following nusinersen treatment in spinal muscular atrophy.
Roles of chitinase 3-like 1 in the development of cancer, neurodegenerative diseases, and inflammatory diseases.
Neuroinflammatory Diseases
Chitotriosidase and lysosomal enzymes as potential biomarkers of disease progression in amyotrophic lateral sclerosis: a survey clinic-based study.
Chitotriosidase, a biomarker of amyotrophic lateral sclerosis, accentuates neurodegeneration in spinal motor neurons through neuroinflammation.
Fungal infection in neural tissue of patients with amyotrophic lateral sclerosis.
Monocyte-Derived Macrophages Contribute to Chitinase Dysregulation in Amyotrophic Lateral Sclerosis: A Pilot Study.
Neurologic Manifestations
Gaucher disease and miscellaneous.
Neuromyelitis Optica
Chitinase effects on immune cell response in neuromyelitis optica and multiple sclerosis.
Niemann-Pick Disease, Type B
Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease.
Niemann-Pick Disease, Type C
Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: a prospective observational study.
Niemann-Pick Diseases
Allelic Frequency of a 24-bp Duplication in Exon 10 of the CHIT1 Gene in the General Iranian Population.
Assessment of plasma chitotriosidase activity, CCL18/PARC concentration and NP-C suspicion index in the diagnosis of Niemann-Pick disease type C: a prospective observational study.
Biochemical characterization of chitotriosidase enzyme: comparison between normal individuals and patients with Gaucher and with Niemann-Pick diseases.
CCL18 as an alternative marker in Gaucher and Niemann-Pick disease with chitotriosidase deficiency.
Chitotriosidase activity as additional biomarker in the diagnosis of lysosomal storage diseases.
Critical assessment of chitotriosidase analysis in the rational laboratory diagnosis of children with Gaucher disease and Niemann-Pick disease type A/B and C.
Hematopoietic stem cell transplantation in Niemann-Pick disease type B monitored by chitotriosidase activity.
Lysosomal Storage Disorders in Indian Children with Neuroregression Attending a Genetic Center.
Neonatal chitotriosidase activity is not predictive for Niemann-Pick disease type A/B: implications for newborn screening for lysosomal storage disorders.
Plasma chitotriosidase and CCL18: early biochemical surrogate markers in type B Niemann-Pick disease.
[Comparison and clinical application of two methods for determination of plasma chitotriosidase activity].
Non-alcoholic Fatty Liver Disease
Association of chitotriosidase genotype with the development of non-alcoholic fatty liver disease.
Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease.
Chitotriosidase: A New Inflammatory Marker in Diabetic Complications.
Potential role of chitotriosidase gene in nonalcoholic Fatty liver disease evolution.
Role of Chitinase 3-Like 1 Protein in the Pathogenesis of Hepatic Insulin Resistance in Nonalcoholic Fatty Liver Disease.
Obesity
Evaluation of chitotriosidase as a biomarker for adipose tissue inflammation in overweight individuals and type 2 diabetic patients.
Multidimensional endotyping in patients with severe asthma reveals inflammatory heterogeneity in matrix metalloproteinases and chitinase 3-like protein 1.
Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study.
The impact of acute aerobic exercise on chitinase 3-like protein 1 and intelectin-1 expression in obesity.
Obstetric Labor, Premature
Increased neopterin level and chitotriosidase activity in pregnant women with threatened preterm labor.
Oligospermia
Investigation of seminal plasma chitotriosidase-1 and leukocyte elastase as potential markers for 'silent' inflammation of the reproductive tract of the infertile male - a pilot study.
Onchocerciasis
Dual protonophore-chitinase inhibitors dramatically affect O. volvulus molting.
Optic Neuritis
Cerebrospinal fluid chitinase-3-like 2 and chitotriosidase are potential prognostic biomarkers in early multiple sclerosis.
Cerebrospinal fluid levels of chitinase 3-like 1 and neurofilament light chain predict multiple sclerosis development and disability after optic neuritis.
Osteoarthritis
Co-Expression and Co-Localization of Cartilage Glycoproteins CHI3L1 and Lubricin in Osteoarthritic Cartilage: Morphological, Immunohistochemical and Gene Expression Profiles.
Human cartilage chitinase 3-like protein 2: cloning, expression, and production of polyclonal and monoclonal antibodies for osteoarthritis detection and identification of potential binding partners.
Machine learning application for development of a data-driven predictive model able to investigate quality of life scores in a rare disease.
Osteolysis
Adverse local tissue reaction (ALTR) associated with corrosion products in metal-on-metal and dual modular neck total hip replacements is associated with upregulation of interferon gamma-mediated chemokine signaling.
An Alternative Macrophage Activation Pathway Regulator, CHIT1, May Provide a Serum and Synovial Fluid Biomarker of Periprosthetic Osteolysis.
Osteomyelitis
CHI3L1 regulation of inflammation and the effects on osteogenesis in a Staphylococcus aureus-induced murine model of osteomyelitis.
Osteonecrosis
Osseous manifestations of adult Gaucher disease in the era of enzyme replacement therapy.
Osteoporosis
Erratum to: Serum chitotriosidase in postmenopausal women with severe osteoporosis.
Serum chitotriosidase in postmenopausal women with severe osteoporosis.
Ovarian Neoplasms
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Overweight
Evaluation of chitotriosidase as a biomarker for adipose tissue inflammation in overweight individuals and type 2 diabetic patients.
Pancreatic Neoplasms
Chitinase 3-like-1 and fibronectin in the cargo of extracellular vesicles shed by human macrophages influence pancreatic cancer cellular response to gemcitabine.
Multiplexed proximity ligation assays to profile putative plasma biomarkers relevant to pancreatic and ovarian cancer.
Prognostic Value of Combined Detection of Serum IL6, YKL-40, and C-reactive Protein in Patients with Unresectable Pancreatic Cancer.
[Detection of chitinase 3-like 1 combined with other biomarkers for diagnosis of pancreatic cancer].
Panniculitis, Peritoneal
Hepatosplenomegalic lipidosis: what unless Gaucher? Adult cholesteryl ester storage disease (CESD) with anemia, mesenteric lipodystrophy, increased plasma chitotriosidase activity and a homozygous lysosomal acid lipase -1 exon 8 splice junction mutation.
Paracoccidioidomycosis
Virulence Vs. Immunomodulation: Roles of the Paracoccin Chitinase and Carbohydrate-Binding Sites in Paracoccidioides brasiliensis Infection.
Paralysis
Niemann-Pick disease type C in adults.
Paraproteinemias
Type I Gaucher disease with severe skeletal destruction, extraosseous extension, and monoclonal gammopathy.
Parasitic Diseases
A 24-bp duplication in exon 10 of human chitotriosidase gene from the sub-Saharan to the Mediterranean area: role of parasitic diseases and environmental conditions.
Acidic mammalian chitinase tuning after enteric helminths eradication in inflammatory respiratory disease patients.
Parkinson Disease
Value of plasma chitotriosidase to assess non-neuronopathic Gaucher disease severity and progression in the era of enzyme replacement therapy.
Periodontitis
Chitinase in whole and glandular human salivas and in whole saliva of patients with periodontal inflammation.
Comparing periodontitis biomarkers in saliva, oral rinse and gingival crevicular fluid: A pilot study.
Effect of periodontal treatment on the activity of chitinase in whole saliva of periodontitis patients.
Identification of Salivary Microbiota and Its Association With Host Inflammatory Mediators in Periodontitis.
The effect of nonsurgical periodontal treatment on serum and saliva chitotriosidase activities in patients with periodontitis and coronary artery disease.
Persistent Infection
Chitinase dependent control of protozoan cyst burden in the brain.
Phytoplasma Disease
A Trichoderma harzianum chitinase destroys the cell wall of the phytopathogen Crinipellis perniciosa, the causal agent of witches' broom disease of cocoa
A trichoderma harzianum chitinase destroys the cell wall of the phytopathogen Crinipellis perniciosa, the causal agent of witches' broom disease of cocoa.
Purification, characterization and structural determination of chitinases produced by Moniliophthora perniciosa.
Use of response surface methodology to examine chitinase regulation in the basidiomycete Moniliophthora perniciosa.
Plague
A comparative study of molecular diagnostic methods designed to detect the crayfish plague pathogen, Aphanomyces astaci.
Analysis of chitinase expression in the crayfish plague fungus Aphanomyces astaci.
Plant Diseases
A chitinase with antifungal activity from naked oat (Avena chinensis) seeds.
Both extracellular chitinase and a new cyclic lipopeptide, chromobactomycin, contribute to the biocontrol activity of Chromobacterium sp. C61.
Cloning and characterization of a novel chitinase gene (chi46) from Chaetomium globosum and identification of its biological activity.
Control of plant diseases by chitinase expressed from cloned DNA in Escherichia coli.
Differential expression of maize chitinases in the presence or absence of Trichoderma harzianum strain T22 and indications of a novel exo- endo-heterodimeric chitinase activity.
Enhancing plant disease suppression by Burkholderia vietnamiensis through chromosomal integration of Bacillus subtilis chitinase gene chi113
Enhancing plant disease suppression by Burkholderia vietnamiensis through chromosomal integration of Bacillus subtilis chitinase gene chi113.
Gene expression profiling of papaya (Carica papaya L.) immune response induced by CTS-N after inoculating PLDMV.
Identification and characterization of a novel chitinase with antifungal activity from 'Baozhu' pear (Pyrus ussuriensis Maxim.).
Identification of an endo-chitinase from Corallococcus sp. EGB and evaluation of its antifungal properties.
The cell factory approach toward biotechnological production of high-value chitosan oligomers and their derivatives: an update.
Pleural Effusion
Chitotriosidase activity in pleural effusions.
Pneumococcal Infections
Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1? and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia.
Pneumonia
A novel chitinase having a unique mode of action from Aspergillus fumigatus YJ-407.
Acidic Mammalian Chitinase Is Not A Critical Target For Allergic Airway Disease.
An IL-4/IL-13 Dual Antagonist Reduces Lung Inflammation, Airway Hyperresponsiveness, and IgE Production in Mice.
Biomarkers of Host Response Predict Primary End-Point Radiological Pneumonia in Tanzanian Children with Clinical Pneumonia: A Prospective Cohort Study.
Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1? and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia.
Functional comparison of recombinant acidic mammalian chitinase with enzyme from murine bronchoalveolar lavage.
Lung chitinolytic activity and chitotriosidase are elevated in chronic obstructive pulmonary disease and contribute to lung inflammation.
Microbial diversity in bioaerosol samples causing ODTS compared to reference bioaerosol samples as measured using Illumina sequencing and MALDI-TOF.
Structure and functional analysis of the Legionella pneumophila chitinase ChiA reveals a novel mechanism of metal-dependent mucin degradation.
Pneumonia, Pneumocystis
Chitinases in Pneumocystis carinii pneumonia.
Polycystic Kidney Diseases
Catalytic efficiency of a multi-domain transglycosylating chitinase from Enterobacter cloacae subsp. cloacae (EcChi2) is influenced by polycystic kidney disease domains.
Characterization of an exochitinase from Epiphyas postvittana nucleopolyhedrovirus (family Baculoviridae).
Role of the N-terminal polycystic kidney disease domain in chitin degradation by chitinase A from a marine bacterium, Alteromonas sp. strain O-7.
Polycystic Ovary Syndrome
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Women with polycystic ovary syndrome have increased plasma chitotriosidase activity: a pathophysiological link between inflammation and impaired insulin sensitivity?
Polycythemia Vera
Serum chitotriosidase: a circulating biomarker in polycythemia vera.
Pre-Eclampsia
Chitotriosidase, interleukin-1 beta and tumor necrosis factor alpha levels in mild preeclampsia.
First-trimester maternal serum metastin, placental growth factor and chitotriosidase levels in pre-eclampsia.
Umbilical artery serum chitotriosidase concentration in pregnancies complicated by preeclampsia and relationship between chitotriosidase levels and fetal blood flow velocity.
Premature Birth
Comparison of early pregnancy serum concentration of neopterin, neopterin/creatinine ratio, C-reactive protein, and chitotriosidase, in pregnant women with birth at term and spontaneous preterm birth.
Primary Myelofibrosis
Serum chitotriosidase: a circulating biomarker in polycythemia vera.
Prion Diseases
CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia.
Prostatic Hyperplasia
Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia.
Prostatic Neoplasms
Elevated YKL40 is associated with advanced prostate cancer (PCa) and positively regulates invasion and migration of PCa cells.
Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia.
Protozoan Infections
Quantitative changes in serum concentration of bovine gut chitinase in Theileria infection.
Psoriasis
A novel marker of systemic inflammation in psoriasis and related comorbidities: chitotriosidase.
Pulmonary Disease, Chronic Obstructive
Chitinase 3-like 1 polymorphisms and risk of chronic obstructive pulmonary disease and asthma in a Chinese population.
Chitinases and Chitinase-Like Proteins in Obstructive Lung Diseases - Current Concepts and Potential Applications.
Chitotriosidase Activity in Plasma and COPD Exacerbations.
Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD.
Chitotriosidase: a marker and modulator of lung disease.
Comparison of serum biomarkers between patients with asthma and with chronic obstructive pulmonary disease.
Functional Properties of Mouse Chitotriosidase Expressed in the Periplasmic Space of Escherichia coli.
Genetic association between human chitinases and lung function in COPD.
INCREASED CHITOTRIOSIDASE IS ASSOCIATED WITH ASPERGILLUS AND FREQUENT EXACERBATIONS IN SOUTH-EAST ASIANS WITH BRONCHIECTASIS.
Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease.
Lung chitinolytic activity and chitotriosidase are elevated in chronic obstructive pulmonary disease and contribute to lung inflammation.
Macrophage chitinase 1 stratifies chronic obstructive lung disease.
New immune pathways from chronic post-viral lung disease.
Overexpression of chitinase 3-like 1/YKL-40 in lung-specific IL-18-transgenic mice, smokers and COPD.
Overexpression of chitotriosidase and YKL-40 in peripheral blood and sputum of healthy smokers and patients with chronic obstructive pulmonary disease.
Upregulation of Chitinase 1 in Alveolar Macrophages of HIV-Infected Smokers.
Pulmonary Eosinophilia
A semisynthetic diterpenoid lactone inhibits NF-?B signalling to ameliorate inflammation and airway hyperresponsiveness in a mouse asthma model.
Pulmonary Fibrosis
A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-?1 Signaling.
Chitinase 1 regulates pulmonary fibrosis by modulating TGF-?/SMAD7 pathway via TGFBRAP1 and FOXO3.
Chitotriosidase activity in patients with interstitial lung diseases.
Chitotriosidase: a marker and modulator of lung disease.
Measurement of Chitinase Activity in Biological Samples.
Modifiers of TGF-?1 effector function as novel therapeutic targets of pulmonary fibrosis.
Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease.
Q Fever
[Q fever in the Chita region.]
Rabies
[Results of a study of natural foci of rabies and evaluation of the risk of hydrophobia in new construction areas of Eastern Siberia and the Far East]
Renal Insufficiency
Clinical utility of chitotriosidase enzyme activity in nephropathic cystinosis.
Respiratory Hypersensitivity
Attenuation of allergic airway inflammation in a murine model of asthma by Licochalcone A.
Kinetic characterization of recombinant human acidic Mammalian chitinase.
Rhinitis, Allergic
Correlation of acidic mammalian chitinase expression with disease severity in patients with moderate/severe persistent allergic rhinitis.
Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Increased expression of acidic mammalian chitinase and chitotriosidase in the nasal mucosa of patients with allergic rhinitis.
[Expression of AMCase mRNA in nasal mucosa of allergic rhinitis in SD rats].
Rhinitis, Allergic, Seasonal
NMR assignments and ligand-binding studies on a two-domain family GH19 chitinase allergen from Japanese cedar (Cryptomeria japonica) pollen.
Wine anaphylaxis in a German patient: IgE-mediated allergy against a lipid transfer protein of grapes.
Sarcoidosis
A CHI3L1 gene polymorphism is associated with serum levels of YKL-40, a novel sarcoidosis marker.
Antifungal medication is efficient in treatment of sarcoidosis.
Bronchoalveolar lavage chitotriosidase activity as a biomarker of sarcoidosis.
Chitotriosidase activity in patients with interstitial lung diseases.
Chitotriosidase activity in sarcoidosis and some other pulmonary diseases.
Chitotriosidase activity in the serum of patients with sarcoidosis and pulmonary tuberculosis.
Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis.
Chitotriosidase and soluble IL-2 receptor: comparison of two markers of sarcoidosis severity.
Chitotriosidase as a marker of disease activity in sarcoidosis.
Chitotriosidase gene polymorphisms and mutations limit the determination of chitotriosidase expression in sarcoidosis.
Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis.
Clinically-useful serum biomarkers for diagnosis and prognosis of sarcoidosis.
Combined application of angiotensin converting enzyme and chitotriosidase analysis improves the laboratory diagnosis of sarcoidosis.
Common chitotriosidase duplication gene polymorphism and clinical outcome status in sarcoidosis.
Correction to: Chitotriosidase: a biomarker of activity and severity in patients with sarcoidosis.
Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis.
Human chitotriosidase: a potential new marker of sarcoidosis severity.
Human Chitotriosidase: a Sensitive Biomarker of Sarcoidosis.
Identification of Active Sarcoidosis Using Chitotriosidase and Angiotensin-Converting Enzyme.
Increased Risk of Atherosclerosis in Patients with Sarcoidosis.
Plasma chitotriosidase and CCL18 as surrogate markers for granulomatous macrophages in sarcoidosis.
Prognostic Biomarkers of Sarcoidosis: A Comparative Study of Serum Chitotriosidase, ACE, Lysozyme, and KL-6.
Serial chitotriosidase measurements in sarcoidosis - Two to five year follow-up study.
Serum chitotriosidase activity in sarcoidosis patients.
Serum levels of chitotriosidase as a marker of disease activity and clinical stage in sarcoidosis.
The Role of Urinary Calcium and Chitotriosidase in a Cohort of Chronic Sarcoidosis Patients.
Verifying Sarcoidosis Activity: Chitotriosidase versus ACE in Sarcoidosis - a Case-control Study.
[Serum chitotriosidase activity as a biomarker of pulmonary sarcoidosis].
Sarcoidosis, Pulmonary
Chitotriosidase activity in the serum of patients with sarcoidosis and pulmonary tuberculosis.
Chitotriosidase analysis in bronchoalveolar lavage of patients with sarcoidosis.
Sarcoma
Glycine rich segments adopt polyproline II helices: Implications for biomolecular condensate formation.
Schistosomiasis
Inflammation during Schistosoma haematobium infection and anti-allergy in pre-school-aged children living in a rural endemic area in Zimbabwe.
Scleroderma, Systemic
Cells from the skin of patients with systemic sclerosis secrete chitinase 3-like protein 1.
Chitotriosidase activity in patients with interstitial lung diseases.
Sepsis
Chitotriosidase deficiency in survivors of Candida sepsis.
Clinical use of plasma chitotriosidase in severe sepsis.
Sepsis in acute myeloid leukaemia patients receiving high-dose chemotherapy: No impact of chitotriosidase and mannose-binding lectin polymorphisms.
Sialic Acid Storage Disease
Novel biochemical abnormalities and genotype in Farber disease.
Siderosis
Serum YKL-40 levels and chitotriosidase activity in patients with beta-thalassemia major.
Silicosis
Identification of differentially expressed genes in rat silicosis model by suppression subtractive hybridization analysis.
[Data on the problem of prevention of silicosis in mines in the Chita region.]
Skin Ulcer
Virulence patterns of Aeromonas eucrenophila isolated from water and infected fish.
Sleep Apnea Syndromes
Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study.
Sleep Apnea, Obstructive
24 bp duplication of CHIT1 gene and determinants of human chitotriosidase activity among participants of EPISONO, a population-based cross-sectional study, São Paulo, Brazil.
Obesity modulates the association between sleep apnea treatment and CHI3L1 levels but not CHIT1 activity in moderate to severe OSA: an observational study.
Spondylitis, Ankylosing
Serum chitotriosidase and neopterin levels in patients with ankylosing spondylitis.
Sporotrichosis
Diagnostic value of fluorescein-labeled chitinase staining in formalin-fixed and paraffin-embedded tissues of fungal disease.
Starvation
Autolysis and aging of Penicillium chrysogenum cultures under carbon starvation: Chitinase production and antifungal effect of allosamidin.
Characterization and functional analyses of the chitinase-encoding genes in the nematode-trapping fungus Arthrobotrys oligospora.
Characterization and heterologous expression of an age-dependent fungal/bacterial type chitinase of Aspergillus nidulans.
Expression of the ech42 (endochitinase) gene of Trichoderma atroviride under carbon starvation is antagonized via a BrlA-like cis-acting element.
Expression of two major chitinase genes of Trichoderma atroviride (T. harzianum P1) is triggered by different regulatory signals.
Fusarium graminearum growth inhibition due to glucose starvation caused by osthol.
Interaction of ammonium, glucose, and chitin regulates the expression of cell wall-degrading enzymes in Trichoderma atroviride strain P1.
Primary structure and expression pattern of the 33-kDa chitinase gene from the mycoparasitic fungus Trichoderma harzianum.
Regulation of chitinase 33 (chit33) gene expression in Trichoderma harzianum.
Transcriptional regulation of a chitinase gene by 20-hydroxyecdysone and starvation in the oriental fruit fly, Bactrocera dorsalis.
Use of a promoterless lacZ gene insertion to investigate chitinase gene expression in the marine bacterium Pseudoalteromonas sp. strain S9.
Stomach Neoplasms
Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through ?-catenin/Erk/Akt signaling in gastric cancer.
Stomatognathic Diseases
Chitinases: Therapeutic Scaffolds for Allergy and Inflammation.
Stroke
Chitotriosidase in patients with acute ischemic stroke.
Plasma levels of the proinflammatory chitin-binding glycoprotein YKL-40, variation in the chitinase 3-like 1 gene (CHI3L1), and incident cardiovascular events.
Prognostic value of plasma chitotriosidase activity in acute stroke patients.
Serum chitotriosidase activity is increased in subjects with atherosclerosis disease.
[Stroke epidemiology and evaluation of risk factors significance for survival of patients during 28 poststroke days in the open population of Chita]
Subarachnoid Hemorrhage
Cerebrospinal fluid and serum chitotriosidase levels in patients with aneurysmal subarachnoid haemorrhage: preliminary results.
Superinfection
The Role of CHI3L1 (Chitinase-3-Like-1) in the Pathogenesis of Infections in Burns in a Mouse Model.
Thrombocythemia, Essential
Serum chitotriosidase: a circulating biomarker in polycythemia vera.
Thrombocytopenia
Acute Gaucher Disease-Like Condition in an Indian Infant with a Novel Biallelic Mutation in the Prosaposin Gene.
Plasma chitotriosidase activity in acute Plasmodium falciparum malaria.
Trichomonas Infections
The chitinase system from Trichomonas vaginalis as a potential target for antimicrobial therapy of urogenital trichomoniasis.
Tuberculosis
Chitotriosidase activity in the serum of patients with sarcoidosis and pulmonary tuberculosis.
Efficacy of serum chitotriosidase activity in early treatment of patients with active tuberculosis and a negative sputum smear.
Evidence for the cytotoxic effects of Mycobacterium tuberculosis phospholipase C towards macrophages.
Evidence for the expression of native Mycobacterium tuberculosis phospholipase C: recognition by immune sera and detection of promoter activity.
Human chitotriosidase polymorphisms G354R and A442V associated with reduced enzyme activity.
Influence of the mouse Bcg, Tbc-1 and xid genes on resistance and immune responses to tuberculosis infection and efficacy of bacille Calmette-Guérin (BCG) vaccination.
The relationship between chitotriosidase activity and tuberculosis.
[Complex exzmination for tuberculosis of the inhabitants of the Tungokochensk region of the Chita district]
[Epidemiologic shifts in tuberculosis in the Chita region]
[Genetic aspects of BCG vaccination in experimental tuberculosis]
[Tuberculosis infection rate among adult population of the Chernyshevsk district of the Chita region]
Tuberculosis, Pulmonary
Chitotriosidase activity in the serum of patients with sarcoidosis and pulmonary tuberculosis.
Serum chitotriosidase activity in pulmonary tuberculosis: response to treatment and correlations with clinical parameters.
Typhoid Fever
A holin/peptidoglycan hydrolase-dependent protein secretion system.
Typhus, Epidemic Louse-Borne
Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki strain E. IV. Persistence of immunity and a note as to differing complement-fixation antigen requirements in post-infection and post-vaccination sera.
Urinary Bladder Neoplasms
Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus.
Uterine Cervical Neoplasms
Chitinase 3 like 1 (CHI3L1) promotes vasculogenic mimicry formation in cervical cancer.
Chitinase 3 like 1 is associated with tumor angiogenesis in cervical cancer.
Correlation of chitinase 3-like 1 single nucleotide polymorphisms and haplotypes with uterine cervical cancer in Taiwanese women.
Uveitis
Effect of chitinase inhibitors on endotoxin-induced uveitis (EIU) in rabbits.
Virus Diseases
Deletion of the Autographa californica nucleopolyhedrovirus chitinase KDEL motif and in vitro and in vivo analysis of the modified virus.
Differential expression of bean chitinase genes by virus infection, chemical treatment and UV irradiation.
Expression of the Cydia pomonella granulovirus matrix metalloprotease enhances Autographa californica multiple nucleopolyhedrovirus virulence and can partially substitute for viral cathepsin.
Partial redistribution of the Autographa californica nucleopolyhedrovirus chitinase in virus-infected cells accompanies mutation of the carboxy-terminal KDEL ER-retention motif.
Silencing of Mythimna separata chitinase genes via oral delivery of in planta-expressed RNAi effectors from a recombinant plant virus.
The expanding spectrum of disorders with elevated plasma chitotriosidase activity: an update.
Wound Infection
[Method of estimation of lysozyme activity in serum with chitin azure as substrate]
Xerostomia
Chitinase expression in parotid glands of non-obese diabetic mice.