Reference on EC 2.8.2.8 - [heparan sulfate]-glucosamine N-sulfotransferase and Organism(s) Mus musculus and UniProt Accession Q3UHN9
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Cheung, W.F.; Eriksson, I.; Kusche-Gulberg, M.; Lindahl, U.; Kjellen, L.
Expression of mouse mastocytoma glucosaminyl N-deacetylase/N-sulfotransferase in human kidney 293 cells results in increased N-sulfation of heparan sulfate
Biochemistry
35
5250-5256
1996
Mus musculus
Orellana, A.; Hirschberg, C.B.; Wei, Z.; Swiedler, S.J.; Ishihara, M.
Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line
J. Biol. Chem.
269
2270-2276
1994
Mus musculus
Eisenman, R.A.; Balasubramanian, A.S.; Marx, W.
3-Phosphoadenylylsulfate:N-desulfoheparin sulfotransferase associated with a postmicrosomal particulate mastocytoma fraction
Arch. Biochem. Biophys.
119
387-397
1967
Mus musculus
Jansson, L.; Hk, M.; Wasteson, A.; Lindahl, U.
Biosynthesis of heparin. Solubilization and partial characterization of N- and O-sulphotransferases
Biochem. J.
149
49-55
1975
Mus musculus
Kusche-Gullberg, M.; Eriksson, I.; Pikas, D.S.; Kjellen, L.
Identification and expression in mouse of two heparan sulfate glucosaminyl N-deacetylase/N-sulfotransferase genes
J. Biol. Chem.
273
11902-11907
1998
Rattus norvegicus, Mus musculus (Q3UHN9), Mus musculus
Aikawa, J.; Grobe, K.; Tsujimoto, M.; Esko, J.D.
Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4
J. Biol. Chem.
276
5876-5882
2001
Homo sapiens (O95803), Homo sapiens (Q9H3R1), Homo sapiens, Mus musculus (P52850), Mus musculus (Q3UHN9), Mus musculus (Q9EQH7), Mus musculus (Q9EQW8), Mus musculus
Grobe, K.; Ledin, J.; Ringvall, M.; Holmborn, K.; Forsberg, E.; Esko, J.D.; Kjellen, L.
Heparan sulfate and development: differential roles of the N-acetylglucosamine N-deacetylase/N-sulfotransferase isozymes
Biochim. Biophys. Acta
1573
209-215
2002
Caenorhabditis elegans, Drosophila melanogaster, Homo sapiens, Homo sapiens (O95803), Homo sapiens (Q9H3R1), Mus musculus, Mus musculus (Q9EQW8), vertebrata
Grobe, K.; Inatani, M.; Pallerla, S.R.; Castagnola, J.; Yamaguchi, Y.; Esko, J.D.
Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function
Development
132
3777-3786
2005
Mus musculus
Yabe, T.; Hata, T.; He, J.; Maeda, N.
Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain
Glycobiology
15
982-993
2005
Mus musculus
Pallerla, S.R.; Pan, Y.; Zhang, X.; Esko, J.D.; Grobe, K.
Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development
Dev. Dyn.
236
556-563
2007
Mus musculus
Pan, Y.; Woodbury, A.; Esko, J.D.; Grobe, K.; Zhang, X.
Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development
Development
133
4933-4944
2006
Mus musculus
Ledin, J.; Ringvall, M.; Thuveson, M.; Eriksson, I.; Wilen, M.; Kusche-Gullberg, M.; Forsberg, E.; Kjellen, L.
Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation
J. Biol. Chem.
281
35727-35734
2006
Mus musculus
Duelli, A.; Roennberg, E.; Waern, I.; Ringvall, M.; Kolset, S.O.; Pejler, G.
Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases
J. Immunol.
183
7073-7083
2009
Mus musculus
Holley, R.J.; Deligny, A.; Wei, W.; Watson, H.A.; Ninonuevo, M.R.; Dagaelv, A.; Leary, J.A.; Bigger, B.W.; Kjellen, L.; Merry, C.L.
Mucopolysaccharidosis type I, unique structure of accumulated heparan sulfate and increased N-sulfotransferase activity in mice lacking alpha-L-iduronidase
J. Biol. Chem.
286
37515-37524
2011
Mus musculus
Gesteira, T.F.; Coulson-Thomas, V.J.; Taunay-Rodrigues, A.; Oliveira, V.; Thacker, B.E.; Juliano, M.A.; Pasqualini, R.; Arap, W.; Tersariol, I.L.; Nader, H.B.; Esko, J.D.; Pinhal, M.A.
Inhibitory peptides of the sulfotransferase domain of the heparan sulfate enzyme, N-deacetylase-N-sulfotransferase-1
J. Biol. Chem.
286
5338-5346
2011
Mus musculus
Bush, K.T.; Crawford, B.E.; Garner, O.B.; Nigam, K.B.; Esko, J.D.; Nigam, S.K.
N-sulfation of heparan sulfate regulates early branching events in the developing mammary gland
J. Biol. Chem.
287
42064-42070
2012
Mus musculus
Deligny, A.; Dierker, T.; Dagaelv, A.; Lundequist, A.; Eriksson, I.; Nairn, A.V.; Moremen, K.W.; Merry, C.L.; Kjellen, L.
NDST2 (N-deacetylase/N-sulfotransferase-2) enzyme regulates heparan sulfate chain length
J. Biol. Chem.
291
18600-18607
2016
Mus musculus (P52850), Mus musculus
Chen, H.; Ambadapadi, S.; Wakefield, D.; Bartee, M.; Yaron, J.R.; Zhang, L.; Archer-Hartmann, S.A.; Azadi, P.; Burgin, M.; Borges, C.; Zheng, D.; Ergle, K.; Muppala, V.; Morshed, S.; Rand, K.; Clapp, W.; Proudfoot, A.; Lucas, A.
Selective deletion of heparan sulfotransferase enzyme, Ndst1, in donor endothelial and myeloid precursor cells significantly decreases acute allograft rejection
Sci. Rep.
8
13433
2018
Mus musculus (Q3UHN9), Mus musculus C57BL/6 (Q3UHN9)