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Anemia
Paroxysmal nocturnal hemoglobinuria: new insights from murine Pig-a-deficient hematopoiesis.
Anemia, Aplastic
A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia.
Anemia, Aplastic
Analysis of PIG-A gene in a patient who developed reciprocal translocation of chromosome 12 and paroxysmal nocturnal hemoglobinuria during follow-up of aplastic anemia.
Anemia, Aplastic
CD59-deficient blood cells and PIG-A gene abnormalities in Japanese patients with aplastic anaemia.
Anemia, Aplastic
Circulating PIG-A mutant T lymphocytes in healthy adults and patients with bone marrow failure syndromes.
Anemia, Aplastic
Could aplastic anaemia be considered a pre-pre-leukaemic disorder?
Anemia, Aplastic
Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia.
Anemia, Aplastic
Genotypic, immunophenotypic and clinical features of Thai patients with paroxysmal nocturnal haemoglobinuria.
Anemia, Aplastic
High frequency of several PIG-A mutations in patients with aplastic anemia and myelodysplastic syndrome.
Anemia, Aplastic
Pathogenesis of selective expansion of PNH clones.
Anemia, Aplastic
PIG-A gene mutations in four Taiwanese patients with paroxysmal nocturnal haemoglobinuria following aplastic anaemia.
Anemia, Aplastic
PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis.
Anemia, Aplastic
The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells.
Anemia, Aplastic
[Immune pathophysiology of refractory anemias]
Anemia, Aplastic
[Paroxysmal nocturnal hemoglobinuria (PNH)]
Anemia, Hemolytic
Cloning and characterization of the mouse PIG-A gene.
Anemia, Hemolytic
Mutations in the PIG-A gene causing paroxysmal nocturnal hemoglobinuria are mainly of the frameshift type.
Anemia, Hemolytic
New insights into paroxysmal nocturnal hemoglobinuria.
Anemia, Hemolytic
Paroxysmal nocturnal hemoglobinuria and liver transplantation, a new paradigm.
Anemia, Hemolytic
Paroxysmal nocturnal hemoglobinuria: When delay in diagnosis and long therapy occurs.
Bone Marrow Failure Disorders
Circulating PIG-A mutant T lymphocytes in healthy adults and patients with bone marrow failure syndromes.
Bone Marrow Failure Disorders
Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm.
Bone Marrow Failure Disorders
Differential apoptosis and Fas expression on GPI-negative and GPI-positive stem cells: a mechanism for the evolution of paroxysmal nocturnal haemoglobinuria.
Bone Marrow Failure Disorders
Murine models of paroxysmal nocturnal hemoglobinuria.
Bone Marrow Failure Disorders
Paroxysmal nocturnal hemoglobinuria: When delay in diagnosis and long therapy occurs.
Breast Neoplasms
Evaluation of PIG-A-mutated granulocytes and ex-vivo binucleated micronucleated lymphocytes frequencies after breast cancer radiotherapy in humans.
Cleft Palate
Developmental abnormalities of glycosylphosphatidylinositol-anchor-deficient embryos revealed by Cre/loxP system.
COVID-19
COVID-19 infection presenting as paroxysmal nocturnal hemoglobinuria.
Down Syndrome
A novel gene, DSCR5, from the distal Down syndrome critical region on chromosome 21q22.2.
Down Syndrome
Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos.
Down Syndrome
Dysregulation of growth factor receptor-bound protein 2 and fascin in hippocampus of mice polytransgenic for chromosome 21 structures.
Down Syndrome
Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2.
Genetic Diseases, Inborn
The in vivo Pig-a gene mutation assay, a potential tool for regulatory safety assessment.
Hemoglobinuria
A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia.
Hemoglobinuria
A knock-out model of paroxysmal nocturnal hemoglobinuria: Pig-a(-) hematopoiesis is reconstituted following intercellular transfer of GPI-anchored proteins.
Hemoglobinuria
A patient with paroxysmal nocturnal hemoglobinuria bearing four independent PIG-A mutant clones.
Hemoglobinuria
A systematic analysis of bone marrow cells by flow cytometry defines a specific phenotypic profile beyond GPI deficiency in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Abnormalities of PIG-A transcripts in granulocytes from patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Acute myelogenous leukemia with PIG-A gene mutation evolved from aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome.
Hemoglobinuria
Analysis of PIG-A gene in a patient who developed reciprocal translocation of chromosome 12 and paroxysmal nocturnal hemoglobinuria during follow-up of aplastic anemia.
Hemoglobinuria
Association of HLA haplotypes with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Both paroxysmal nocturnal hemoglobinuria (PNH) type II cells and PNH type III cells can arise from different point mutations involving the same codon of the PIG-A gene.
Hemoglobinuria
Cancer as an evolutionary process at the cell level: an epidemiological perspective.
Hemoglobinuria
CD52/GPI- T-Cells Are Enriched for Alloreactive Specificity and Predict Acute Graft-Versus-Host-Disease After Stem Cell Transplantation.
Hemoglobinuria
Characterization of alternatively spliced PIG-A transcripts in normal and paroxysmal nocturnal hemoglobinuria cells.
Hemoglobinuria
Characterization of genomic PIG-A gene: a gene for glycosylphosphatidylinositol-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Circulating PIG-A mutant T lymphocytes in healthy adults and patients with bone marrow failure syndromes.
Hemoglobinuria
Clinical paroxysmal nocturnal hemoglobinuria is the result of expansion of glycosyl-phosphatidyl-inositol-anchored protein-deficient clone in the condition of deficient hematopoiesis.
Hemoglobinuria
Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals.
Hemoglobinuria
Cloning and characterization of the mouse PIG-A gene.
Hemoglobinuria
Consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria.
Hemoglobinuria
Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro.
Hemoglobinuria
Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Deletions of Xp22.2 including PIG-A locus lead to paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Detection of somatic mutations of the PIG-A gene in Brazilian patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm.
Hemoglobinuria
Different roles of glycosylphosphatidylinositol in various hematopoietic cells as revealed by a mouse model of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Eculizumab in the management of paroxysmal nocturnal hemoglobinuria: patient selection and special considerations.
Hemoglobinuria
Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Frequent detection of T cells with mutations of the hypoxanthine-guanine phosphoribosyl transferase gene in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Function and malfunction of hematopoietic stem cells in primary bone marrow failure syndromes.
Hemoglobinuria
Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells.
Hemoglobinuria
Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?".
Hemoglobinuria
Genetic instability and the etiology of somatic PIG-A mutations in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.
Hemoglobinuria
GPI-anchor synthesis in mammalian cells: genes, their products, and a deficiency.
Hemoglobinuria
Hemoglobinuria misidentified as hematuria: review of discolored urine and paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Hemolytic anemia.
Hemoglobinuria
Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
High frequency of several PIG-A mutations in patients with aplastic anemia and myelodysplastic syndrome.
Hemoglobinuria
How do PIG-A mutant paroxysmal nocturnal hemoglobinuria stem cells achieve clonal dominance?
Hemoglobinuria
Identification of a PIG-A related processed gene on chromosome 12.
Hemoglobinuria
Immune pathogenesis of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone.
Hemoglobinuria
Increased resistance of PIG-A- bone marrow progenitors to tumor necrosis factor a and interferon gamma: possible implications for the in vivo dominance of paroxysmal nocturnal hemoglobinuria clones.
Hemoglobinuria
Laboratory studies for paroxysmal nocturnal hemoglobinuria, with emphasis on flow cytometry.
Hemoglobinuria
Leukemia arising out of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Mean fluorescence intensity rate is a useful marker in the detection of paroxysmal nocturnal hemoglobinuria clones.
Hemoglobinuria
Molecular cloning of murine pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus.
Hemoglobinuria
Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.
Hemoglobinuria
Mutations in the PIG-A gene causing paroxysmal nocturnal hemoglobinuria are mainly of the frameshift type.
Hemoglobinuria
New insights into paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
New somatic mutation in the PIG-A gene emerges at relapse of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria and liver transplantation, a new paradigm.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome: a case report.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria: analysis of the effects of mutant PIG-A on gene expression.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria: molecular pathogenesis and molecular therapeutic approaches.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria: significant association with specific HLA-A, -B, -C, and -DR alleles in an Italian population.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria: Test to monitor the action of eculizumab treatment.
Hemoglobinuria
Paroxysmal nocturnal hemoglobinuria: When delay in diagnosis and long therapy occurs.
Hemoglobinuria
Pathogenesis of selective expansion of PNH clones.
Hemoglobinuria
Phenotypes and phosphatidylinositol glycan-class A gene abnormalities during cell differentiation and maturation from precursor cells to mature granulocytes in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
PIG-A gene abnormalities in Thai patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis.
Hemoglobinuria
PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor.
Hemoglobinuria
Postpartum thrombotic complication in a patient with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Proliferative capacity of single isolated CD34+ hematopoietic stem/progenitor cells in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Rare Hematological Disease of Paroxysmal Nocturnal Hemoglobinuria With Profound Implications for a Gastroenterologist: A Case Report and Literature Review.
Hemoglobinuria
Resistance to apoptosis caused by PIG-A gene mutations in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Response of paroxysmal nocturnal hemoglobinuria clone with aplastic anemia to rituximab.
Hemoglobinuria
Role of phosphatidylinositol-linked proteins in paroxysmal nocturnal hemoglobinuria pathogenesis.
Hemoglobinuria
Somatic mutation and clonal selection in the pathogenesis and in the control of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Somatic mutations and the hierarchy of hematopoiesis.
Hemoglobinuria
Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Structural and functional analysis of the Pig-a protein that is mutated in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
Successful unrelated donor bone marrow transplantation for paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
The distribution of PIG-A gene abnormalities in paroxysmal nocturnal hemoglobinuria granulocytes and cultured erythroblasts.
Hemoglobinuria
The mutation rate in PIG-A is normal in patients with paroxysmal nocturnal hemoglobinuria (PNH).
Hemoglobinuria
The Patterns of MHC Association in Aplastic and Non-aplastic Paroxysmal Nocturnal Hemoglobinuria.
Hemoglobinuria
The PIG-A gene somatic mutation responsible for paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
The PIG-A mutation and absence of glycosylphosphatidylinositol-linked proteins do not confer resistance to apoptosis in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria
The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells.
Hemoglobinuria
The spectrum of PIG-A gene mutations in aplastic anemia/paroxysmal nocturnal hemoglobinuria (AA/PNH): a high incidence of multiple mutations and evidence of a mutational hot spot.
Hemoglobinuria
The spectrum of somatic mutations in the PIG-A gene in paroxysmal nocturnal hemoglobinuria includes large deletions and small duplications.
Hemoglobinuria
The yeast spt14 gene is homologous to the human PIG-A gene and is required for GPI anchor synthesis.
Hemoglobinuria
[Eculizumab in paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria
[Gene diagnosis of hemolytic anemia]
Hemoglobinuria
[Immune pathophysiology of refractory anemias]
Hemoglobinuria
[Mutations in the PIG-A gene lead to GPI-deficiency in paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria
[Paroxysmal nocturnal hemoglobinuria--consequences of a missing anchor]
Hemoglobinuria
[Paroxysmal nocturnal hemoglobinuria.]
Hemoglobinuria
[PIG-A gene mutation and paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria
[Somatic mutations of PIG-A gene in Chinese patients with paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria
[Spontaneous recovery from pancytopenia in a young female patient with paroxysmal nocturnal hemoglobinuria(PNH): changes in the GPI-anchor expression on peripheral blood cells]
Hemoglobinuria
[The evaluation and comparative characteristic of detection of clone of paroxysmal nocturnal hemoglobinuria on reticulocytes using the technique of flow cytometry].
Hemoglobinuria, Paroxysmal
A cohort study of the nature of paroxysmal nocturnal hemoglobinuria clones and PIG-A mutations in patients with aplastic anemia.
Hemoglobinuria, Paroxysmal
A knock-out model of paroxysmal nocturnal hemoglobinuria: Pig-a(-) hematopoiesis is reconstituted following intercellular transfer of GPI-anchored proteins.
Hemoglobinuria, Paroxysmal
A patient with paroxysmal nocturnal hemoglobinuria bearing four independent PIG-A mutant clones.
Hemoglobinuria, Paroxysmal
A systematic analysis of bone marrow cells by flow cytometry defines a specific phenotypic profile beyond GPI deficiency in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Abnormalities of PIG-A transcripts in granulocytes from patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Analysis of PIG-A gene in a patient who developed reciprocal translocation of chromosome 12 and paroxysmal nocturnal hemoglobinuria during follow-up of aplastic anemia.
Hemoglobinuria, Paroxysmal
Association of HLA haplotypes with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Both paroxysmal nocturnal hemoglobinuria (PNH) type II cells and PNH type III cells can arise from different point mutations involving the same codon of the PIG-A gene.
Hemoglobinuria, Paroxysmal
Cancer as an evolutionary process at the cell level: an epidemiological perspective.
Hemoglobinuria, Paroxysmal
CD52/GPI- T-Cells Are Enriched for Alloreactive Specificity and Predict Acute Graft-Versus-Host-Disease After Stem Cell Transplantation.
Hemoglobinuria, Paroxysmal
Characterization of alternatively spliced PIG-A transcripts in normal and paroxysmal nocturnal hemoglobinuria cells.
Hemoglobinuria, Paroxysmal
Characterization of genomic PIG-A gene: a gene for glycosylphosphatidylinositol-anchor biosynthesis and paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Circulating PIG-A mutant T lymphocytes in healthy adults and patients with bone marrow failure syndromes.
Hemoglobinuria, Paroxysmal
Clinical paroxysmal nocturnal hemoglobinuria is the result of expansion of glycosyl-phosphatidyl-inositol-anchored protein-deficient clone in the condition of deficient hematopoiesis.
Hemoglobinuria, Paroxysmal
Clonal populations of hematopoietic cells with paroxysmal nocturnal hemoglobinuria genotype and phenotype are present in normal individuals.
Hemoglobinuria, Paroxysmal
Cloning and characterization of the mouse PIG-A gene.
Hemoglobinuria, Paroxysmal
Consensus statement for diagnosis and treatment of paroxysmal nocturnal haemoglobinuria.
Hemoglobinuria, Paroxysmal
Decreased susceptibility of leukemic cells with PIG-A mutation to natural killer cells in vitro.
Hemoglobinuria, Paroxysmal
Deficiency of the GPI anchor caused by a somatic mutation of the PIG-A gene in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Deletions of Xp22.2 including PIG-A locus lead to paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Detection of somatic mutations of the PIG-A gene in Brazilian patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm.
Hemoglobinuria, Paroxysmal
Different roles of glycosylphosphatidylinositol in various hematopoietic cells as revealed by a mouse model of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Eculizumab in the management of paroxysmal nocturnal hemoglobinuria: patient selection and special considerations.
Hemoglobinuria, Paroxysmal
Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Frequent detection of T cells with mutations of the hypoxanthine-guanine phosphoribosyl transferase gene in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Function and malfunction of hematopoietic stem cells in primary bone marrow failure syndromes.
Hemoglobinuria, Paroxysmal
Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells.
Hemoglobinuria, Paroxysmal
Genetic and environmental effects in paroxysmal nocturnal hemoglobinuria: this little PIG-A goes "Why? Why? Why?".
Hemoglobinuria, Paroxysmal
Genetic instability and the etiology of somatic PIG-A mutations in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Glycosylphosphatidylinositol-anchored protein deficiency confers resistance to apoptosis in PNH.
Hemoglobinuria, Paroxysmal
GPI-anchor synthesis in mammalian cells: genes, their products, and a deficiency.
Hemoglobinuria, Paroxysmal
Hemoglobinuria misidentified as hematuria: review of discolored urine and paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Hemolytic anemia.
Hemoglobinuria, Paroxysmal
Heterogeneous PIG-A mutations in different cell lineages in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
High frequency of several PIG-A mutations in patients with aplastic anemia and myelodysplastic syndrome.
Hemoglobinuria, Paroxysmal
How do PIG-A mutant paroxysmal nocturnal hemoglobinuria stem cells achieve clonal dominance?
Hemoglobinuria, Paroxysmal
Identification of a PIG-A related processed gene on chromosome 12.
Hemoglobinuria, Paroxysmal
Immune pathogenesis of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Impaired hematopoiesis in paroxysmal nocturnal hemoglobinuria/aplastic anemia is not associated with a selective proliferative defect in the glycosylphosphatidylinositol-anchored protein-deficient clone.
Hemoglobinuria, Paroxysmal
Increased resistance of PIG-A- bone marrow progenitors to tumor necrosis factor a and interferon gamma: possible implications for the in vivo dominance of paroxysmal nocturnal hemoglobinuria clones.
Hemoglobinuria, Paroxysmal
Laboratory studies for paroxysmal nocturnal hemoglobinuria, with emphasis on flow cytometry.
Hemoglobinuria, Paroxysmal
Leukemia arising out of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Long-term support of hematopoiesis by a single stem cell clone in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Mean fluorescence intensity rate is a useful marker in the detection of paroxysmal nocturnal hemoglobinuria clones.
Hemoglobinuria, Paroxysmal
Molecular cloning of murine pig-a, a gene for GPI-anchor biosynthesis, and demonstration of interspecies conservation of its structure, function, and genetic locus.
Hemoglobinuria, Paroxysmal
Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.
Hemoglobinuria, Paroxysmal
Mutations in the PIG-A gene causing paroxysmal nocturnal hemoglobinuria are mainly of the frameshift type.
Hemoglobinuria, Paroxysmal
New insights into paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
New somatic mutation in the PIG-A gene emerges at relapse of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
On the origin of multiple mutant clones in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria and liver transplantation, a new paradigm.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome: a case report.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria and the age of therapeutic complement inhibition.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria: analysis of the effects of mutant PIG-A on gene expression.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria: molecular pathogenesis and molecular therapeutic approaches.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria: significant association with specific HLA-A, -B, -C, and -DR alleles in an Italian population.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria: Test to monitor the action of eculizumab treatment.
Hemoglobinuria, Paroxysmal
Paroxysmal nocturnal hemoglobinuria: When delay in diagnosis and long therapy occurs.
Hemoglobinuria, Paroxysmal
Pathogenesis of selective expansion of PNH clones.
Hemoglobinuria, Paroxysmal
Phenotypes and phosphatidylinositol glycan-class A gene abnormalities during cell differentiation and maturation from precursor cells to mature granulocytes in patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
PIG-A gene abnormalities in Thai patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesis.
Hemoglobinuria, Paroxysmal
PIG-B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor.
Hemoglobinuria, Paroxysmal
Postpartum thrombotic complication in a patient with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Proliferative capacity of single isolated CD34+ hematopoietic stem/progenitor cells in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Rare Hematological Disease of Paroxysmal Nocturnal Hemoglobinuria With Profound Implications for a Gastroenterologist: A Case Report and Literature Review.
Hemoglobinuria, Paroxysmal
Resistance to apoptosis caused by PIG-A gene mutations in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Response of paroxysmal nocturnal hemoglobinuria clone with aplastic anemia to rituximab.
Hemoglobinuria, Paroxysmal
Role of phosphatidylinositol-linked proteins in paroxysmal nocturnal hemoglobinuria pathogenesis.
Hemoglobinuria, Paroxysmal
Somatic mutation and clonal selection in the pathogenesis and in the control of paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Somatic mutations and the hierarchy of hematopoiesis.
Hemoglobinuria, Paroxysmal
Somatic mutations of PIG-A in Thai patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Somatic mutations of the PIG-A gene found in Japanese patients with paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Structural and functional analysis of the Pig-a protein that is mutated in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
Successful unrelated donor bone marrow transplantation for paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
The distribution of PIG-A gene abnormalities in paroxysmal nocturnal hemoglobinuria granulocytes and cultured erythroblasts.
Hemoglobinuria, Paroxysmal
The mutation rate in PIG-A is normal in patients with paroxysmal nocturnal hemoglobinuria (PNH).
Hemoglobinuria, Paroxysmal
The Patterns of MHC Association in Aplastic and Non-aplastic Paroxysmal Nocturnal Hemoglobinuria.
Hemoglobinuria, Paroxysmal
The PIG-A gene somatic mutation responsible for paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
The PIG-A mutation and absence of glycosylphosphatidylinositol-linked proteins do not confer resistance to apoptosis in paroxysmal nocturnal hemoglobinuria.
Hemoglobinuria, Paroxysmal
The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells.
Hemoglobinuria, Paroxysmal
The spectrum of somatic mutations in the PIG-A gene in paroxysmal nocturnal hemoglobinuria includes large deletions and small duplications.
Hemoglobinuria, Paroxysmal
The yeast spt14 gene is homologous to the human PIG-A gene and is required for GPI anchor synthesis.
Hemoglobinuria, Paroxysmal
[Eculizumab in paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria, Paroxysmal
[Gene diagnosis of hemolytic anemia]
Hemoglobinuria, Paroxysmal
[Immune pathophysiology of refractory anemias]
Hemoglobinuria, Paroxysmal
[Mutations in the PIG-A gene lead to GPI-deficiency in paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria, Paroxysmal
[Paroxysmal nocturnal hemoglobinuria--consequences of a missing anchor]
Hemoglobinuria, Paroxysmal
[Paroxysmal nocturnal hemoglobinuria.]
Hemoglobinuria, Paroxysmal
[PIG-A gene mutation and paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria, Paroxysmal
[Somatic mutations of PIG-A gene in Chinese patients with paroxysmal nocturnal hemoglobinuria]
Hemoglobinuria, Paroxysmal
[Spontaneous recovery from pancytopenia in a young female patient with paroxysmal nocturnal hemoglobinuria(PNH): changes in the GPI-anchor expression on peripheral blood cells]
Hemoglobinuria, Paroxysmal
[The evaluation and comparative characteristic of detection of clone of paroxysmal nocturnal hemoglobinuria on reticulocytes using the technique of flow cytometry].
Hemoglobinuria, Paroxysmal
[THE METHODICAL APPROACHES TO DIAGNOSTIC OF NIGHT PAROXYSMAL HEMOGLOBINURIA].
Ichthyosis, Lamellar
Epidermal-specific defect of GPI anchor in Pig-a null mice results in Harlequin ichthyosis-like features.
Inflammatory Bowel Diseases
Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays.
Inflammatory Bowel Diseases
The potential application of human PIG-A assay on azathioprine-treated inflammatory bowel disease patients.
Leukemia
N-RAS gene mutation in patients with aplastic anemia and aplastic anemia/ paroxysmal nocturnal hemoglobinuria during evolution to clonal disease.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Somatic mutations and the hierarchy of hematopoiesis.
Leukemia, Myeloid, Acute
Acute myelogenous leukemia with PIG-A gene mutation evolved from aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome.
Lymphoma
The development of an in vitro Pig-a assay in L5178Y cells.
Malnutrition
Moderate malnutrition in rats induces somatic gene mutations.
Myelodysplastic Syndromes
High frequency of several PIG-A mutations in patients with aplastic anemia and myelodysplastic syndrome.
Myelodysplastic Syndromes
Pathogenesis of selective expansion of PNH clones.
Myelodysplastic Syndromes
The small population of PIG-A mutant cells in myelodysplastic syndromes do not arise from multipotent hematopoietic stem cells.
Myelodysplastic Syndromes
[Clinical and laboratory characteristics in patients of myelodysplastic syndrome with PNH clones].
Myeloproliferative Disorders
Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm.
Neoplasms
A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene.
Neoplasms
Biological and molecular characterization of PNH-like lymphocytes emerging after Campath-1H therapy.
Neoplasms
Monitoring genotoxicity in patients receiving chemotherapy for cancer: application of the PIG-A assay.
Neoplasms
Monitoring humans for somatic mutation in the endogenous pig-a gene using red blood cells.
Neoplasms, Plasma Cell
A quantitative analysis of genomic instability in lymphoid and plasma cell neoplasms based on the PIG-A gene.
Obesity
Diet-induced obesity increases the frequency of Pig-a mutant erythrocytes in male C57BL/6J mice.
Protein Deficiency
Glycosylphosphatidylinositol (GPI) anchored protein deficiency serves as a reliable reporter of Pig-a gene Mutation: Support from an in vitro assay based on L5178Y/Tk
Seizures
Generation of glycosylphosphatidylinositol anchor protein-deficient blood cells from human induced pluripotent stem cells.
Starvation
The PIG-A mutation and absence of glycosylphosphatidylinositol-linked proteins do not confer resistance to apoptosis in paroxysmal nocturnal hemoglobinuria.
Thrombophilia
Rare Hematological Disease of Paroxysmal Nocturnal Hemoglobinuria With Profound Implications for a Gastroenterologist: A Case Report and Literature Review.
Thrombosis
Development of paroxysmal nocturnal hemoglobinuria in CALR-positive myeloproliferative neoplasm.
Thrombosis
Paroxysmal nocturnal hemoglobinuria: When delay in diagnosis and long therapy occurs.
Thymoma
Direct evidence of involvement of glycosylphosphatidylinositol-anchored proteins in the heavy metal-mediated signal delivery into T lymphocytes.
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2.4.1.198 phosphatidylinositol N-acetylglucosaminyltransferase
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The reliability class of the localization prediction ranges from 1 (very reliable) to 5 (not reliable). 
