6.3.2.39: aerobactin synthase

This is an abbreviated version!
For detailed information about aerobactin synthase, go to the full flat file.

Reaction

Synonyms

aerC, EC 6.3.2.27, iuacC, iucC

ECTree

     6 Ligases

         6.3 Forming carbon-nitrogen bonds

             6.3.2 Acid—amino-acid ligases (peptide synthases)

                6.3.2.39 aerobactin synthase

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Results	in table
208	AA Sequence
1	CAS Registry Number
1	General Information
2	Inhibitors
1	Metals/Ions
2	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
9	Organism
7	Pathway
1	Purification (Commentary)
1	Reaction
7	Reference
8	Substrates and Products (Substrate)
5	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Substrates Products

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Substrates Products on EC 6.3.2.39 - aerobactin synthase

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SUBSTRATE

PRODUCT                       

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

Reversibility
r=reversible
ir=irreversible
?=not specified

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

2 entries

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

6 entries

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Escherichia coli

-

-

719292

-

-

?

2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine

Escherichia coli

-

the enzyme is involved in biosynthesis of aerobactin

719292

-

-

?

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

Escherichia coli

-

-

720473

-

-

?

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

Escherichia coli

Q47318

-

486099

-

-

?

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

Klebsiella aerogenes

-

-

492296

-

-

?

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

Klebsiella aerogenes

-

the enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate in biosynthesis of aerobactin. Aerobactin is excreted by cultures of Aerobacter aerogenes 62-I and related strains when growing in an iron-deficient medium

719001

-

-

?

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

Klebsiella aerogenes 62-1

-

-

492296

-

-

?

2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O

2 ADP + 2 phosphate + aerobactin

Klebsiella aerogenes 62-1

-

the enzyme catalyses the second of two synthase reactions to link N6-acetyl-N6-hydroxy-L-lysine and citrate in biosynthesis of aerobactin. Aerobactin is excreted by cultures of Aerobacter aerogenes 62-I and related strains when growing in an iron-deficient medium

719001

-

-

?