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6.3.1.14: diphthine-ammonia ligase

This is an abbreviated version!
For detailed information about diphthine-ammonia ligase, go to the full flat file.

Reaction

ATP
+
diphthine-[translation elongation factor 2]
+
NH3
=
AMP
+
diphosphate
+
diphthamide-[translation elongation factor 2]

Synonyms

Diphthamide synthase, diphthamide synthetase, DPH6, EC 6.3.2.22, Synthetase, diphthamide, YLR143w

ECTree

     6 Ligases
         6.3 Forming carbon-nitrogen bonds
             6.3.1 Acid—ammonia (or amine) ligases (amide synthases)
                6.3.1.14 diphthine-ammonia ligase

Natural Substrates Products

Natural Substrates Products on EC 6.3.1.14 - diphthine-ammonia ligase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
ATP + diphthine-[translation elongation factor 2] + NH3
AMP + diphosphate + diphthamide-[translation elongation factor 2]
show the reaction diagram