6.2.1.41: 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase

This is an abbreviated version!
For detailed information about 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase, go to the full flat file.

Reaction

Synonyms

fadD3, HIP-CoA ligase

ECTree

     6 Ligases

         6.2 Forming carbon-sulfur bonds

             6.2.1 Acid-thiol ligases

                6.2.1.41 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
367	AA Sequence
1	Cloned(Commentary)
1	Inhibitors
3	kcat/KM [mM/s]
3	KM Value [mM]
1	Natural Substrates/ Products (Substrates)
1	Organism
7	Pathway
1	Purification (Commentary)
1	Reaction
1	Reference
3	Substrates and Products (Substrate)
4	Synonyms
1	Systematic Name
3	Turnover Number [1/s]

Systematic Name

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Systematic Name on EC 6.2.1.41 - 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate-CoA ligase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Systematic Name Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

SYSTEMATIC NAME

IUBMB Comments

3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate:CoA ligase (AMP-forming)

The enzyme, characterized from actinobacterium Mycobacterium tuberculosis, catalyses a step in the degradation of cholesterol and cholate. The enzyme is very specific for its substrate, and requires that the side chain at C17 is completely removed.