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5.4.99.41: lupeol synthase

This is an abbreviated version!
For detailed information about lupeol synthase, go to the full flat file.

Word Map on EC 5.4.99.41

Reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene
=
lupeol

Synonyms

2,3-oxidosqualene-triterpenoid cyclase, At1g78970, AtLUP1, BPY, LUP1, lupeol synthase, LUS, MdOSC5, OEW, OSC3, OSC5, RcLUS, TRW

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.41 lupeol synthase

Systematic Name

Systematic Name on EC 5.4.99.41 - lupeol synthase

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SYSTEMATIC NAME
IUBMB Comments
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, lupeol-forming)
Also forms some beta-amyrin. The recombinant enzyme from Arabidopsis thaliana [3] gives a 1:1 mixture of lupeol and lupan-3beta,20-diol with small amounts of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol. See EC 4.2.1.128 (lupan-3beta,20-diol synthase).