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5.4.99.31: thalianol synthase

This is an abbreviated version!
For detailed information about thalianol synthase, go to the full flat file.

Reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene
=
thalianol

Synonyms

At5g48010, THAS1

ECTree

     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.31 thalianol synthase

Cloned

Cloned on EC 5.4.99.31 - thalianol synthase

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CLONED (Commentary)
ORGANISM
UNIPROT
LITERATURE
gene THAS1, recombinant expression in Rhodobacter capsulatus strain SB1003. and Synechocystis sp. PCC 6803 using promoters Pnif and PcoaT, coexpression with CAS1, LUP1, and MRN1. Subcloning in Saccharomyces cerevisiae strain GIL77. Isolation of triterpenes, while cycloartenol and lupeol represent typical plant triterpenes with tetracyclic plant sterol and pentacyclic plant triterpene scaffolds, respectively, thalianol and marneral exhibit more unusual tri- and monocyclic structures