5.4.99.19: 16S rRNA pseudouridine516 synthase

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For detailed information about 16S rRNA pseudouridine516 synthase, go to the full flat file.

Reaction

Synonyms

16S PSI516 synthase, 16S RNA pseudouridine 516 synthase, 16S RNA PSI516 synthase, PSI-synthase RsuA, RNA pseudouridine synthase RsuA, RsuA

ECTree

     5 Isomerases

         5.4 Intramolecular transferases

             5.4.99 Transferring other groups

                5.4.99.19 16S rRNA pseudouridine516 synthase

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Results	in table
201	AA Sequence
2	Cloned(Commentary)
1	Crystallization (Commentary)
1	General Information
1	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
3	Organism
1	pH Optimum
2	Protein Variants
2	Purification (Commentary)
1	Reaction
3	Reference
2	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Natural Substrates Products

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Natural Substrates Products on EC 5.4.99.19 - 16S rRNA pseudouridine516 synthase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

16S rRNA uridine516

16S rRNA pseudouridine516

Escherichia coli

P0AA43

in vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins, suggesting that pseudouridylation occurs at an intermediate stage of 30S assembly in vivo

702191

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