4.2.3.77: (+)-germacrene D synthase

This is an abbreviated version!
For detailed information about (+)-germacrene D synthase, go to the full flat file.

Reaction

Synonyms

GDS, GDS1, Sc11, TPS2

ECTree

     4 Lyases

         4.2 Carbon-oxygen lyases

             4.2.3 Acting on phosphates

                4.2.3.77 (+)-germacrene D synthase

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9	AA Sequence
2	Application
5	Cloned(Commentary)
2	kcat/KM [mM/s]
3	KM Value [mM]
1	Localization
9	Metals/Ions
4	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
7	Organism
1	Pathway
1	pH Optimum
1	pH Range
2	pI Value
2	Protein Variants
2	Purification (Commentary)
2	Reaction
7	Reference
3	Source Tissue
7	Substrates and Products (Substrate)
3	Subunits
4	Synonyms
1	Systematic Name
3	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 4.2.3.77 - (+)-germacrene D synthase

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SYSTEMATIC NAME

IUBMB Comments

2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-D-forming]

Requires Mg2+, Mn2+, Ni2+ or Co2+. The formation of (+)-germacrene D involves a 1,2-hydride shift whereas for (-)-germacrene D there is a 1,3-hydride shift (see EC 4.2.3.75).