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4.1.3.41: 3-hydroxy-D-aspartate aldolase

This is an abbreviated version!
For detailed information about 3-hydroxy-D-aspartate aldolase, go to the full flat file.

Reaction

D-erythro-3-hydroxyaspartate
=
glycine
+
glyoxylate

Synonyms

D-3-hydroxyaspartate aldolase, d-HAA

ECTree

     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.41 3-hydroxy-D-aspartate aldolase

Substrates Products

Substrates Products on EC 4.1.3.41 - 3-hydroxy-D-aspartate aldolase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-amino-3-hydroxybutanedioic acid
aminoacetic acid + oxoacetic acid
show the reaction diagram
-
-
-
r
allo-threonine
?
show the reaction diagram
-
-
-
?
D-3-3,4-dihydroxyphenylserine
?
show the reaction diagram
-
-
-
?
D-erythro-3-3,4-methylenedioxyphenylserine
?
show the reaction diagram
-
-
-
?
D-erythro-3-hydroxyaspartate
glycine + glyoxylate
show the reaction diagram
the enzyme is strictly D-specific as to the alpha-position, whereas it does not distinguish between threo and erythro forms at the beta-position
-
-
?
D-erythro-3-phenylserine
?
show the reaction diagram
-
-
-
?
D-threo-3-3,4-methylenedioxyphenylserine
?
show the reaction diagram
-
-
-
?
D-threo-3-phenylserine
?
show the reaction diagram
-
-
-
?
additional information
?
-
the enzyme shows no activity towards L-erythro-3-hydroxyaspartate, L-threo-3-hydroxyaspartate, L-threonine, L-allo-threonine, L-erythro-3-phenylserine, L-threo-3-phenylserine, L-erythro-3-3,4-methylenedioxyphenylserine, and L-threo-3-3,4-methylenedioxyphenylserine
-
-
?