4.1.1.12: aspartate 4-decarboxylase

This is an abbreviated version!
For detailed information about aspartate 4-decarboxylase, go to the full flat file.

Word Map on EC 4.1.1.12

4.1.1.12

desulfurization

dibenzothiophene

dacunhae

2-hydroxybiphenyl

biodesulfurization

erythropolis

beta-decarboxylation

polythioesters

3,3'-dithiodipropionic

dtdp

carbon-sulfur

mimigardefordensis

betaproteobacterium

advenella

synthesis

industry

Reaction

Synonyms

ABDC, ADC, Aminomalonic decarboxylase, Asd, aspartate 4-carboxylyase, Aspartate beta-decarboxylase, Aspartate omega-decarboxylase, aspartate-beta-decarboxylase, Aspartic beta-decarboxylase, Aspartic omega-decarboxylase, Cysteine sulfinic desulfinase, Decarboxylase, aspartate 4-, Desulfinase, EC 4.1.1.10, L-Asparate 4-carboxy-lyase, L-aspartate 4-decarboxylase, L-Aspartate beta-decarboxylase, L-Cysteine sulfinate acid desulfinase, PanD

ECTree

4 Lyases

4.1 Carbon-carbon lyases

4.1.1 Carboxy-lyases

4.1.1.12 aspartate 4-decarboxylase

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Results	in table
42	Activating Compound
311	AA Sequence
4	Application
1	CAS Registry Number
9	Cloned(Commentary)
18	Cofactor
7	Crystallization (Commentary)
2	General Stability
46	Inhibitors
22	KM Value [mM]
2	Localization
9	Metals/Ions
12	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
46	Organism
5	Pathway
20	PDB ID
15	pH Optimum
6	pH Range
5	pH Stability
1	pI Value
30	Protein Variants
11	Purification (Commentary)
3	Reaction
4	Reaction Type
46	Reference
15	Source Tissue
14	Specific Activity [micromol/min/mg]
5	Storage Stability
74	Substrates and Products (Substrate)
13	Subunits
33	Synonyms
1	Systematic Name
10	Temperature Optimum [°C]
6	Temperature Range [°C]
3	Temperature Stability [°C]
10	Turnover Number [1/s]

Activating Compound

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Activating Compound on EC 4.1.1.12 - aspartate 4-decarboxylase

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2-mercaptoethanol

Pseudomonas sp.

Q53IZ1

1 mM, 7% activation

677736

2-Oxo-5-carbamidopentanoate

Alcaligenes faecalis

activates

3955

2-oxo-5-guanidinopentanoate

activates

2-oxoglutarate

2-Oxoisohexanoate

activates

2-oxoisopentanoate

activates

2-Oxomalonate

activates

2-oxophenylacetate

activates

acetaldehyde

activates

beta-cyano-L-Ala

competitive towards L-Asp

3955

D-2-Oxo-3-methylpentanoate

Alcaligenes faecalis

activates

3955

DL-erythro-3-hydroxyaspartate

Pseudomonas dacunhae

3958

DL-threo-3-hydroxyaspartate

Pseudomonas dacunhae

DTT

1 mM, 7% activation

EDTA

10-20 mM, 10% activation

glutamate

stimulates

Glyoxal

activates

glyoxylate

L-2-Oxo-3-methylpentanoate

activates

oxalacetate

phenylpyruvate

activates

pyruvate

Ser

acticates liver enzyme, competitively inhibits kidney and brain enzyme

3961

additional information

Alcaligenes faecalis

interacts with a number of vitamin B6 5'-phosphate analogues

3955