3.8.1.11: 2-haloacid dehalogenase (configuration-retaining)

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Reaction

Synonyms

2-haloalkanoic acid dehalogenase, 2-haloalkanoid acid halidohydrolase, DL-2-haloacid dehalogenase, DL-DEXr

ECTree

     3 Hydrolases

         3.8 Acting on halide bonds

             3.8.1 In carbon-halide compounds

                3.8.1.11 2-haloacid dehalogenase (configuration-retaining)

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Systematic Name on EC 3.8.1.11 - 2-haloacid dehalogenase (configuration-retaining)

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SYSTEMATIC NAME

IUBMB Comments

(S)-2-haloacid dehalogenase (configuration-retaining)

Dehalogenates both (S)- and (R)-2-haloalkanoic acids to the corresponding (S)- and (R)-hydroxyalkanoic acids, respectively, with retention of configuration at C-2. [See also EC 3.8.1.2 (S)-2-haloacid dehalogenase, EC 3.8.1.9 (R)-2-haloacid dehalogenase and EC 3.8.1.10 2-haloacid dehalogenase (configuration-inverting)]