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3.6.1.63: alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase

This is an abbreviated version!
For detailed information about alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase, go to the full flat file.

Reaction

alpha-D-ribose 1-methylphosphonate 5-triphosphate
+
H2O
=
alpha-D-ribose 1-methylphosphonate 5-phosphate
+
diphosphate

Synonyms

phnM

ECTree

     3 Hydrolases
         3.6 Acting on acid anhydrides
             3.6.1 In phosphorus-containing anhydrides
                3.6.1.63 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase

General Information

General Information on EC 3.6.1.63 - alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
malfunction
-
in vivo complementation of the strains, in which phnC to phnP or phnH to phnP are deleted, with plasmids carrying various fragments of the phn operon reveal that the expression of phnC-phnP gene products is essential to restore growth on minimal medium with phosphonate as the sole phosphorus source, while phnG-phnM gene products are required for carbon-phosphorus lyase activity. The minimum size of the DNA required for the whole-cell carbon-phosphorus lyase activity is determined to be a 5.8-kb fragment, encompassing the phnG to phnM genes
physiological function
-
nine gene products (PhnG, PhnH, PhnI, PhnJ, PhnK, PhnL, PhnM, PhnN, and PhnP) comprise a membrane-associated carbon-phosphorus lyase enzyme complex