3.5.4.28: S-adenosylhomocysteine deaminase

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For detailed information about S-adenosylhomocysteine deaminase, go to the full flat file.

deaminase, adenosylhomocysteine, MJ1541

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Results	in table
1	Activating Compound
7694	AA Sequence
1	CAS Registry Number
1	Cloned(Commentary)
2	General Information
1	General Stability
4	Inhibitors
4	kcat/KM [mM/s]
5	KM Value [mM]
4	Metals/Ions
4	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
3	Organism
2	PDB ID
1	pH Optimum
1	pH Range
5	Protein Variants
2	Purification (Commentary)
1	Reaction
1	Reaction Type
3	Reference
1	Specific Activity [micromol/min/mg]
4	Substrates and Products (Substrate)
3	Subunits
3	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
4	Temperature Stability [°C]
5	Turnover Number [1/s]

Engineering on EC 3.5.4.28 - S-adenosylhomocysteine deaminase

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C294S

the wild-type and the C294S mutant strains are stable after heating for 10 min at 60°C

E150R

less thermostable than wild-type enzyme, stable for 10 min at 50°C

Y136R

less thermostable than wild-type enzyme, stable for 10 min at 50°C

Y136R/E150R

no activity with adenosine

C294S

the wild-type and the C294S mutant strains are stable after heating for 10 min at 60°C