3.5.1.59: N-carbamoylsarcosine amidase
This is an abbreviated version!
For detailed information about N-carbamoylsarcosine amidase, go to the full flat file.
Word Map on EC 3.5.1.59
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3.5.1.59
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creatinine
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arthrobacter
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intersubunit
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n-methylhydantoin
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pyrazinamidase
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putida
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isomorphous
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r-factor
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cytosine
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isochorismatase
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sheet
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six-stranded
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cis-peptide
- 3.5.1.59
- creatinine
- arthrobacter
-
intersubunit
- n-methylhydantoin
- pyrazinamidase
- putida
-
isomorphous
-
r-factor
- cytosine
- isochorismatase
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sheet
-
six-stranded
-
cis-peptide
Reaction
Synonyms
amidase, carbamoylsarcosine, CSHase, N-carbamoylsarcosine amidase Ta0454, N-carbamoylsarcosine amidohydrolase
ECTree
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Substrates Products
Substrates Products on EC 3.5.1.59 - N-carbamoylsarcosine amidase
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REACTION DIAGRAM
N-carbamoyl-D-alanine + H2O
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hydrolysis at 7% the rate of N-carbamoylsarcosine
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-
?
N-carbamoylglycine + H2O
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hydrolysis at 10% the rate of N-carbamoylsarcosine
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?
N-methyl-N-carbamoyl-D-alanine + H2O
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hydrolysis at 13% the rate of N-carbamoylsarcosine
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-
?
N-carbamoylsarcosine + H2O
sarcosine + CO2 + NH3
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inducible enzyme
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?
N-carbamoylsarcosine + H2O
sarcosine + CO2 + NH3
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best substrate
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ir
N-carbamoylsarcosine + H2O
sarcosine + CO2 + NH3
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inducible enzyme
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?
N-carbamoylsarcosine + H2O
sarcosine + CO2 + NH3
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creatine pathway
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ir
N-carbamoylsarcosine + H2O
sarcosine + CO2 + NH3
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inducible enzyme
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?
N-carbamoylsarcosine + H2O
sarcosine + CO2 + NH3
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inducible enzyme
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?
?
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high substrate specificity: no hydrolysis of substrate analoges (N-carbamoyl amino acids)
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additional information
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poor substrates are N-carbamoyl derivatives of DL-tryptophan, DL-phenylalanine, 4-hydroxy-DL-phenylglycine, D-valine, 4-methyl-DL-phenylglycine, DL-2-amino-n-butyric acid, DL-threonine or D-leucine. No substrates are N-carbamoyl derivatives of L-glutamic acid, L-valine, L-tyrosine, L-isoleucine, L-histidine, L-asparagine, DL-aspartic acid, L-serine, DL-methionine or 2-aminoisobutyric acid
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?